SG11201913229PA - Silk-hyaluronic acid based tissue fillers and methods of using the same - Google Patents

Silk-hyaluronic acid based tissue fillers and methods of using the same

Info

Publication number
SG11201913229PA
SG11201913229PA SG11201913229PA SG11201913229PA SG11201913229PA SG 11201913229P A SG11201913229P A SG 11201913229PA SG 11201913229P A SG11201913229P A SG 11201913229PA SG 11201913229P A SG11201913229P A SG 11201913229PA SG 11201913229P A SG11201913229P A SG 11201913229PA
Authority
SG
Singapore
Prior art keywords
silk
methods
same
hyaluronic acid
acid based
Prior art date
Application number
SG11201913229PA
Other languages
English (en)
Inventor
Gregory H Altman
Peng Xu
Erlei Jin
Original Assignee
Evolved By Nature Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evolved By Nature Inc filed Critical Evolved By Nature Inc
Publication of SG11201913229PA publication Critical patent/SG11201913229PA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402—Anaestetics, analgesics, e.g. lidocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG11201913229PA 2017-06-26 2018-06-26 Silk-hyaluronic acid based tissue fillers and methods of using the same SG11201913229PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762525131P 2017-06-26 2017-06-26
US201862641095P 2018-03-09 2018-03-09
PCT/US2018/039574 WO2019005848A1 (en) 2017-06-26 2018-06-26 HYALURONIC SILK ACID TISSUE FILLING AGENTS AND METHODS OF USE THEREOF

Publications (1)

Publication Number Publication Date
SG11201913229PA true SG11201913229PA (en) 2020-01-30

Family

ID=64742709

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201913229PA SG11201913229PA (en) 2017-06-26 2018-06-26 Silk-hyaluronic acid based tissue fillers and methods of using the same

Country Status (13)

Country Link
EP (2) EP4169539B1 (https=)
JP (3) JP2020525253A (https=)
KR (1) KR20200032103A (https=)
CN (1) CN111263646A (https=)
AU (2) AU2018290810C1 (https=)
CA (1) CA3068296A1 (https=)
CO (1) CO2020000774A2 (https=)
ES (2) ES2935887T3 (https=)
IL (2) IL299584A (https=)
MA (1) MA49520A (https=)
SG (1) SG11201913229PA (https=)
UA (1) UA127350C2 (https=)
WO (1) WO2019005848A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11660372B2 (en) 2017-06-26 2023-05-30 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue fillers and methods of using the same
US12296067B2 (en) 2018-12-19 2025-05-13 Evolved By Nature, Inc. Silk-hyaluronic acid tissue fillers and methods of making and using the same
US12611484B2 (en) 2023-04-25 2026-04-28 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue filers and methods of using the same

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6508431B1 (ja) 2017-09-21 2019-05-08 住友電気工業株式会社 半絶縁性ヒ化ガリウム結晶基板
US20220193305A1 (en) * 2019-03-29 2022-06-23 Trustees Of Tufts College Crosslinked silk fibroin-based compositions, and methods of making and using the same
AU2020289479A1 (en) * 2019-06-06 2022-02-03 Evolved By Nature, Inc. Silk stimulated collagen production and methods of use thereof
WO2020262596A1 (en) * 2019-06-26 2020-12-30 Compagnie Generale Des Etablissements Michelin A noise improving tread
CN110339398A (zh) * 2019-07-18 2019-10-18 王月玲 一种含氨基酸透明质酸钠注射剂及其制备方法
EP4017537A4 (en) * 2019-08-20 2023-08-16 Evolved by Nature, Inc. SILK PERSONAL CARE PRODUCTS
EP3995530B1 (en) * 2019-09-27 2025-05-28 LG Chem, Ltd. A method of preparing polymer microparticles, polymer microparticles, medical composition, cosmetic composition, medical articles, and cosmetic articles using the same
PL4077402T3 (pl) * 2019-12-19 2024-07-29 Croma-Pharma Gmbh Kwas hialuronowy modyfikowany tiolem i hydrożel zawierający usieciowany kwas hialuronowy
CN116507315A (zh) * 2020-06-19 2023-07-28 自然进化公司 用于组织填充、组织间隔和组织膨胀的丝-透明质酸组合物
US20250295691A1 (en) * 2020-06-19 2025-09-25 Evolved By Nature, Inc. Silk-Hyaluronic Acid Compositions For Tissue Filling, Tissue Spacing, and Tissue Bulking
JP2024519426A (ja) * 2020-09-29 2024-05-14 ジロパ・インコーポレイテッド 疼痛の緩和及び麻痺のための組成物及び方法
TR202101065A1 (tr) * 2021-01-25 2022-08-22 Hacettepe Ueniversitesi Hyaluroni̇k asi̇t jel i̇çeren bi̇r doku dolgu malzemesi̇ ve üreti̇m yöntemi̇
CN114213517B (zh) * 2021-02-08 2024-07-09 复向丝泰医疗科技(苏州)有限公司 利用切向流超滤技术制备可控高浓度丝素蛋白溶液的方法
JP7695344B2 (ja) 2021-05-21 2025-06-18 ケンブリッジ クロップス インコーポレイテッド． ドゥーイングビジネスアズ モリ 絹フィブロイン溶液及び絹フィブロインを含む粉末を製造するためのシステム及び方法
WO2023275278A1 (en) * 2021-06-30 2023-01-05 Merz Pharma Gmbh & Co. Kgaa Hyaluronic acid dermal fillers crosslinked with polyethylene glycol diglycidyl ether, method for making same and uses thereof
CN113368220A (zh) * 2021-07-05 2021-09-10 云南维他源生物科技有限公司 一种ahco组合物及其制剂与应用
KR20230013682A (ko) 2021-07-16 2023-01-27 주식회사 휴메딕스 Pegde로 가교된 히알루론산 필러 및 이의 제조방법
US11864569B2 (en) 2021-08-16 2024-01-09 Cambridge Crops, Inc. Systems and methods for improving the performance of cereal using a silk fibroin solution and powders containing silk fibroin
CN114028610B (zh) * 2021-10-26 2022-10-25 北京诺康达医药科技股份有限公司 一种亲水性注射型皮肤填充组合物及其制备方法与应用
KR102766244B1 (ko) * 2024-02-16 2025-02-10 충남대학교 산학협력단 Lc-ms/ms 기반의 히알루론산, bdde 및 bdde 가교된 히알루론산의 정량방법

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH453269A4 (https=) 1968-03-29 1973-01-31
FR2334107A1 (fr) 1975-12-05 1977-07-01 Pasteur Institut Procede de couplage de substances biologiques par des liaisons covalentes
US4355023A (en) 1980-09-30 1982-10-19 The Massachusetts General Hospital Antibody fragment compositions and process
US4657853A (en) 1984-09-14 1987-04-14 E. I. Du Pont De Nemours And Company Immunoassays utilizing covalent conjugates of polymerized enzyme and antibody
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
US20060105022A1 (en) 2004-11-15 2006-05-18 Shiseido Co., Ltd. Process for preparing crosslinked hyaluronic acid gel
US8357795B2 (en) * 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
US20110189292A1 (en) 2009-04-20 2011-08-04 Allergan, Inc. Dermal fillers comprising silk fibroin hydrogels and uses thereof
WO2011059325A2 (en) * 2009-11-11 2011-05-19 University Of Twente, Institute For Biomedical Technology And Technical Medicine (Mira) Dextran-hyaluronic acid based hydrogels
KR102238406B1 (ko) * 2011-06-03 2021-04-08 알러간 인더스트리 에스에이에스 항산화제를 포함하는 피부 충전제 조성물
CN108379112A (zh) * 2011-09-14 2018-08-10 阿勒根公司 用于细纹治疗的真皮填充剂组合物
CN102836465B (zh) * 2012-08-30 2014-06-04 浙江星月生物科技股份有限公司 一种注射用丝素蛋白透明质酸复合凝胶及其制备与应用
WO2014055895A1 (en) * 2012-10-05 2014-04-10 Allergan, Inc. Injectable device and method for sculpting, augmenting or correcting facial features such as the chin
US20140315828A1 (en) * 2013-04-22 2014-10-23 Allergan, Inc. Cross-linked silk-hyaluronic acid compositions
HK1224315A1 (zh) 2013-06-28 2017-08-18 Galderma S.A. 用於制备交联的透明质酸产物的方法
CA2925820C (en) * 2013-09-30 2021-11-30 Silk Therapeutics, Inc. Silk protein fragment compositions and articles manufactured therefrom
EA035551B1 (ru) 2014-12-02 2020-07-06 Силк Терапьютикс, Инк. Изделие
MX2017013949A (es) * 2015-04-29 2018-11-09 Silk Therapeutics Inc Composiciones mectantes a base de seda y sus metodos.
US10175996B2 (en) 2016-05-02 2019-01-08 Norman R. Byrne Information display and control for work areas
EP3503841A4 (en) * 2016-08-24 2020-04-22 Allergan, Inc. CO-CROSSLINKED HYALURONIC ACID-FIBROIN HYDROGELS FOR IMPROVING THE SUSTAINABILITY OF TISSUE GRAFTS AND FOR INCREASING SOFT TISSUES

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11660372B2 (en) 2017-06-26 2023-05-30 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue fillers and methods of using the same
US12296067B2 (en) 2018-12-19 2025-05-13 Evolved By Nature, Inc. Silk-hyaluronic acid tissue fillers and methods of making and using the same
US12611484B2 (en) 2023-04-25 2026-04-28 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue filers and methods of using the same

Also Published As

Publication number Publication date
JP2020525253A (ja) 2020-08-27
EP4169539A1 (en) 2023-04-26
AU2024219582A1 (en) 2024-10-03
ES2935887T3 (es) 2023-03-13
AU2018290810C1 (en) 2024-09-12
US20230338614A1 (en) 2023-10-26
UA127350C2 (uk) 2023-07-26
JP2025020289A (ja) 2025-02-12
EP3645063A4 (en) 2021-04-14
EP4169539B1 (en) 2025-01-29
EP4169539C0 (en) 2025-01-29
JP2023139249A (ja) 2023-10-03
WO2019005848A1 (en) 2019-01-03
KR20200032103A (ko) 2020-03-25
AU2018290810B2 (en) 2024-06-13
JP7660619B2 (ja) 2025-04-11
EP3645063A1 (en) 2020-05-06
CN111263646A (zh) 2020-06-09
CA3068296A1 (en) 2019-01-03
CO2020000774A2 (es) 2020-05-05
IL299584A (en) 2023-03-01
IL271692B2 (en) 2023-06-01
ES3018883T3 (en) 2025-05-19
IL271692A (en) 2020-02-27
EP3645063B1 (en) 2022-09-28
MA49520A (fr) 2021-04-14
AU2018290810A1 (en) 2020-02-13
BR112019027687A2 (pt) 2020-09-15

Similar Documents

Publication Publication Date Title
IL271692A (en) Tissue fillers based on hyaluronic acid and silk and methods of using them
IL284082A (en) Silk-hyaluronic acid tissue fillers and methods for their preparation and use
IL268406A (en) Preparations and methods for treating hemoglobin diseases
IL260257A (en) Preparations and methods for the treatment of hemoglobinopathies
GB201513461D0 (en) Methods and devices for the production of decellularised tissue scaffolds
EP3242709A4 (en) Cardiac stimulation of atrial-ventricle pathways and/or associated tissue
EP3185795A4 (en) Bone fixation devices and methods
EP3154533A4 (en) Methods of anesthetizing nerve tissue in the trigeminal nerve pathway and medical uses thereof
IL275182A (en) Preparations and methods for the treatment of metabolic conditions
ZA202104969B (en) Compositions comprising 15-hepe and methods of using the same
SG11201705450SA (en) Bacteria-comprising compositions and methods of using the same for treating and/or preventing gastrointestinal, metabolic and/or other diseases
EP3224362A4 (en) Therapeutic compositions comprising transcription factors and methods of making and using the same
IL272937A (en) Preparations and methods for the treatment of diseases involving fibrosis
EP3496804A4 (en) BIOELECTRIC DEVICES AND METHODS OF USE
EP3209340A4 (en) Microfabricated tissue scaffolds and methods of making and using the same
GB201709840D0 (en) Methods and medical uses
IL248210A0 (en) Methods and preparations for the treatment of blood vessel malformations
EP3282857A4 (en) Human milk compositions and methods of making and using same
EP3139850A4 (en) Methods and devices for attaching or reattaching soft tissue to bone
WO2019070510A9 (en) Intrabody osteotomy implant and methods of use
EP3229826A4 (en) Methods of promoting tissue healing and repair
MX2019010640A (es) Formas cristalinas de acido obeticolico.
EP3334730A4 (en) Pyrrolomycins and methods of using the same
ZA201900984B (en) Methods and compositions for the treatment of warts
SG10201606557RA (en) Oxygen-enriched water composition, biocompatible composition comprising the same, and methods of preparing and using the same