SG11201705991XA - Rotavirus-like particle production in plants - Google Patents

Rotavirus-like particle production in plants

Info

Publication number
SG11201705991XA
SG11201705991XA SG11201705991XA SG11201705991XA SG11201705991XA SG 11201705991X A SG11201705991X A SG 11201705991XA SG 11201705991X A SG11201705991X A SG 11201705991XA SG 11201705991X A SG11201705991X A SG 11201705991XA SG 11201705991X A SG11201705991X A SG 11201705991XA
Authority
SG
Singapore
Prior art keywords
rotavirus
plants
particle production
particle
production
Prior art date
Application number
SG11201705991XA
Other languages
English (en)
Inventor
Pierre-Olivier Lavoie
Marc-Andre D'aoust
Original Assignee
Medicago Inc
Mitsubishi Tanabe Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicago Inc, Mitsubishi Tanabe Pharma Corp filed Critical Medicago Inc
Publication of SG11201705991XA publication Critical patent/SG11201705991XA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04Inactivation or attenuation; Producing viral sub-units
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02Recovery or purification
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12311Rotavirus, e.g. rotavirus A
    • C12N2720/12322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12311Rotavirus, e.g. rotavirus A
    • C12N2720/12323Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12311Rotavirus, e.g. rotavirus A
    • C12N2720/12334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12311Rotavirus, e.g. rotavirus A
    • C12N2720/12351Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SG11201705991XA 2015-01-23 2016-01-21 Rotavirus-like particle production in plants SG11201705991XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562106941P 2015-01-23 2015-01-23
PCT/CA2016/050043 WO2016115630A1 (en) 2015-01-23 2016-01-21 Rotavirus-like particle production in plants

Publications (1)

Publication Number Publication Date
SG11201705991XA true SG11201705991XA (en) 2017-08-30

Family

ID=56416224

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201705991XA SG11201705991XA (en) 2015-01-23 2016-01-21 Rotavirus-like particle production in plants

Country Status (17)

Country Link
US (2) US10287555B2 (de)
EP (1) EP3256575B1 (de)
JP (1) JP6841762B2 (de)
KR (1) KR20170104595A (de)
CN (1) CN107208072A (de)
AU (1) AU2016208999A1 (de)
BR (1) BR112017014160A2 (de)
CA (1) CA2974438A1 (de)
EA (1) EA201791683A1 (de)
ES (1) ES2826402T3 (de)
HK (1) HK1245333A1 (de)
IL (1) IL253040A0 (de)
MX (1) MX2017009568A (de)
PH (1) PH12017501330A1 (de)
SG (1) SG11201705991XA (de)
WO (1) WO2016115630A1 (de)
ZA (1) ZA201705555B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102647829B1 (ko) * 2020-04-22 2024-03-14 포항공과대학교 산학협력단 삼량체를 형성하는 코로나-19 바이러스 (COVID-19, Coronavirus Disease 2019)의 재조합 스파이크 단백질 및 식물에서의 상기 재조합 스파이크 단백질의 대량 생산 방법과 이를 기반으로하는 백신조성물 제조 방법
CN112251461B (zh) * 2020-10-22 2022-08-23 植链(上海)生物科技有限公司 一种采用本氏烟作为生物反应器制备的轮状病毒疫苗及其制备方法和应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5428147A (en) 1983-04-15 1995-06-27 Mycogen Plant Science, Inc. Octopine T-DNA promoters
EP0152295B1 (de) 1984-02-09 1991-03-20 Royal Children's Hospital Research Foundation Lebender attenuierter menschlicher Rotavirus-Impfstoff und Herstellung desselben
US4636385A (en) 1985-02-15 1987-01-13 The Wistar Institute Of Anatomy & Biology Vaccine, method for its preparation, and use thereof in vaccinating humans against rotavirus infection
US4704275A (en) 1985-08-26 1987-11-03 The United States Of America As Represented By The Department Of Health And Human Services Vaccine against rotavirus diseases
US4751080A (en) 1985-08-26 1988-06-14 The United States Of America As Represented By The Department Of Health And Human Services Vaccine against rotavirus diseases
US4927628A (en) 1987-09-21 1990-05-22 The United States Of America As Represented By The Department Of Health And Human Services Vaccine against rotavirus diseases and method of preparing same
CA2096315C (en) 1990-11-16 1996-11-19 Richard L. Ward Human rotaviruses, vaccines and methods
US20050186219A1 (en) 1997-10-07 2005-08-25 Langridge William H. Transgenic plant-based vaccines
US7125978B1 (en) 1999-10-04 2006-10-24 Medicago Inc. Promoter for regulating expression of foreign genes
WO2001059070A1 (en) 2000-02-12 2001-08-16 Kim Won Yong Production method of recombinant rotavirus structural proteins and vaccine composition
FR2806087B1 (fr) 2000-03-07 2002-10-18 Agronomique Inst Nat Rech Particules pseudovirales de rotavirus et leur utilisation pour vectoriser des proteines ou des acides nucleiques
WO2002036172A2 (en) * 2000-11-03 2002-05-10 Baylor College Of Medicine Rotavirus enterotoxin nsp4 and methods of using same
ES2514316T3 (es) 2005-11-22 2014-10-28 Novartis Vaccines And Diagnostics, Inc. Partículas similares a virus (VLPs) de Norovirus y Sapovirus
CA2651907C (en) 2006-05-22 2016-12-20 Plant Bioscience Limited Bipartite system, method and composition for the constitutive and inducible expression of high levels of foreign proteins in plants
CA2615372A1 (en) 2007-07-13 2009-01-13 Marc-Andre D'aoust Influenza virus-like particles (vlps) comprising hemagglutinin
CN103122354B (zh) 2007-11-27 2018-03-23 麦迪卡格公司 表达血凝素之转基因植物中生产的重组流感病毒样颗粒(vlp)
GB0800272D0 (en) 2008-01-08 2008-02-13 Plant Bioscience Ltd Protein expression systems
CA2726131C (en) 2008-05-29 2018-03-13 Baoming Jiang Expression and assembly of human group c rotavirus-like particles and uses thereof
AU2011325827B2 (en) 2010-11-04 2016-08-04 Medicago Inc. Plant expression system
EP2718428B1 (de) * 2011-06-13 2018-03-07 Medicago Inc. Herstellung rabiesvirus-ähnlicher partikel in pflanzen
AU2013258849B2 (en) 2012-05-11 2018-12-13 Medicago Inc. Rotavirus-like particle production in plants

Also Published As

Publication number Publication date
JP2018504119A (ja) 2018-02-15
HK1245333A1 (zh) 2018-08-24
EA201791683A1 (ru) 2017-12-29
PH12017501330A1 (en) 2017-12-18
CA2974438A1 (en) 2016-07-28
WO2016115630A1 (en) 2016-07-28
EP3256575A1 (de) 2017-12-20
US10287555B2 (en) 2019-05-14
ZA201705555B (en) 2020-01-29
IL253040A0 (en) 2017-08-31
JP6841762B2 (ja) 2021-03-10
MX2017009568A (es) 2018-03-01
US20190345454A1 (en) 2019-11-14
KR20170104595A (ko) 2017-09-15
US20180016561A1 (en) 2018-01-18
ES2826402T3 (es) 2021-05-18
BR112017014160A2 (pt) 2018-01-02
EP3256575B1 (de) 2020-07-29
EP3256575A4 (de) 2018-10-31
AU2016208999A1 (en) 2017-07-13
CN107208072A (zh) 2017-09-26

Similar Documents

Publication Publication Date Title
HUE046384T2 (hu) Gyártóberendezés és gyártási eljárás
GB201405614D0 (en) Particles
PL3195927T3 (pl) Sposób wytwarzania cząstki kompozytowej
GB201600631D0 (en) Modified plant
GB2533999B (en) Power plant
GB2591025B (en) Improvements in tablet manufacture
IL246593A0 (en) Increased protein expression in plants
GB201412841D0 (en) Particles
PL3040176T3 (pl) Instalacja produkcyjna
HK1250911A1 (zh) 微凝膠顆粒
GB201506074D0 (en) Object production
HK1245333A1 (zh) 在植物中產生輪狀病毒樣顆粒
GB201320387D0 (en) Plant production
ZA201700867B (en) Modifying protein production in plants
GB201523035D0 (en) In terferometry
GB2532451B (en) Object production
ZA201708393B (en) Large particles
EP3109243A4 (de) Gamma-butylolactonzusammensetzung und verfahren zur herstellung
PL2949390T3 (pl) Instalacja adsorpcyjna
GB201308218D0 (en) Chlor-Alkali Process and Plant
IL247727B (en) RNA production in higher plants
GB202004939D0 (en) Modified plant
GB201507344D0 (en) Novel particles
GB201504562D0 (en) Object production
GB201510202D0 (en) Hydroelectric plant