SG11201704841UA - Method of protein manufacture - Google Patents
Method of protein manufactureInfo
- Publication number
- SG11201704841UA SG11201704841UA SG11201704841UA SG11201704841UA SG11201704841UA SG 11201704841U A SG11201704841U A SG 11201704841UA SG 11201704841U A SG11201704841U A SG 11201704841UA SG 11201704841U A SG11201704841U A SG 11201704841UA SG 11201704841U A SG11201704841U A SG 11201704841UA
- Authority
- SG
- Singapore
- Prior art keywords
- protein manufacture
- protein
- manufacture
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J47/00—Ion-exchange processes in general; Apparatus therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/50—Soluble polymers, e.g. polyethyleneglycol [PEG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14199722 | 2014-12-22 | ||
PCT/EP2015/080526 WO2016102378A1 (en) | 2014-12-22 | 2015-12-18 | Method of protein manufacture |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201704841UA true SG11201704841UA (en) | 2017-07-28 |
Family
ID=52282495
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201704841UA SG11201704841UA (en) | 2014-12-22 | 2015-12-18 | Method of protein manufacture |
Country Status (16)
Country | Link |
---|---|
US (1) | US10626143B2 (en) |
EP (1) | EP3237433A1 (en) |
JP (1) | JP6807326B2 (en) |
KR (1) | KR102537099B1 (en) |
CN (1) | CN107108691B (en) |
AU (1) | AU2015371341B2 (en) |
BR (1) | BR112017013398B1 (en) |
CA (1) | CA2969981C (en) |
CL (1) | CL2017001633A1 (en) |
CO (1) | CO2017006157A2 (en) |
EA (1) | EA039002B1 (en) |
IL (1) | IL252712B2 (en) |
MX (1) | MX2017007670A (en) |
MY (1) | MY184085A (en) |
SG (1) | SG11201704841UA (en) |
WO (1) | WO2016102378A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2969889A1 (en) | 2014-12-22 | 2016-06-30 | Ucb Biopharma Sprl | Protein manufacture |
CN110386978A (en) * | 2018-04-19 | 2019-10-29 | 上海多米瑞生物技术有限公司 | The extracting method of the albumen of colibacillus periplasm space expression |
CN111965356B (en) * | 2019-11-28 | 2023-09-08 | 上海荣盛生物药业股份有限公司 | Sulfhydryl reduction composition, fluorescent microsphere chromatography test paper and application |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9215540D0 (en) | 1992-07-22 | 1992-09-02 | Celltech Ltd | Protein expression system |
US5655866A (en) | 1995-03-20 | 1997-08-12 | Bellanca; Joseph V. | Method of folding a signature for use in bookbinding |
CA2364568A1 (en) * | 1999-03-17 | 2000-09-21 | Adrian Woolfson | Method for refolding molecules of polypeptides containing ig domains |
GB0013810D0 (en) | 2000-06-06 | 2000-07-26 | Celltech Chiroscience Ltd | Biological products |
MX2007004437A (en) * | 2004-10-22 | 2007-06-20 | Amgen Inc | Methods for refolding of recombinant antibodies. |
WO2006060083A1 (en) * | 2004-10-22 | 2006-06-08 | Amgen Inc. | Methods for refolding polypeptides |
GB0425534D0 (en) | 2004-11-19 | 2004-12-22 | Celltech R&D Ltd | Process for obtaining antibodies |
GB0513852D0 (en) * | 2005-07-06 | 2005-08-10 | Celltech R&D Ltd | Biological products |
NZ573639A (en) | 2006-07-14 | 2012-03-30 | Genentech Inc | Refolding of recombinant proteins |
US8617531B2 (en) * | 2006-12-14 | 2013-12-31 | Bolder Biotechnology, Inc. | Methods of making proteins and peptides containing a single free cysteine |
GB201001791D0 (en) | 2010-02-03 | 2010-03-24 | Ucb Pharma Sa | Process for obtaining antibodies |
BR112012022518A2 (en) | 2010-03-17 | 2020-10-13 | Biogenerix Gmbh | method for obtaining biologically active recombinant human g-csf |
GB201012603D0 (en) | 2010-07-27 | 2010-09-08 | Ucb Pharma Sa | Protein purification |
GB201012599D0 (en) | 2010-07-27 | 2010-09-08 | Ucb Pharma Sa | Process for purifying proteins |
US20130273607A1 (en) | 2010-10-20 | 2013-10-17 | Medimmune, Llc | Methods for processing inclusion bodies |
CA2969889A1 (en) | 2014-12-22 | 2016-06-30 | Ucb Biopharma Sprl | Protein manufacture |
GB201506870D0 (en) | 2015-04-22 | 2015-06-03 | Ucb Biopharma Sprl | Method |
-
2015
- 2015-12-18 IL IL252712A patent/IL252712B2/en unknown
- 2015-12-18 KR KR1020177020637A patent/KR102537099B1/en active IP Right Grant
- 2015-12-18 CA CA2969981A patent/CA2969981C/en active Active
- 2015-12-18 JP JP2017551008A patent/JP6807326B2/en active Active
- 2015-12-18 AU AU2015371341A patent/AU2015371341B2/en active Active
- 2015-12-18 EA EA201791423A patent/EA039002B1/en unknown
- 2015-12-18 EP EP15813438.7A patent/EP3237433A1/en active Pending
- 2015-12-18 MX MX2017007670A patent/MX2017007670A/en unknown
- 2015-12-18 BR BR112017013398-9A patent/BR112017013398B1/en active IP Right Grant
- 2015-12-18 SG SG11201704841UA patent/SG11201704841UA/en unknown
- 2015-12-18 CN CN201580070976.9A patent/CN107108691B/en active Active
- 2015-12-18 MY MYPI2017702190A patent/MY184085A/en unknown
- 2015-12-18 US US15/538,282 patent/US10626143B2/en active Active
- 2015-12-18 WO PCT/EP2015/080526 patent/WO2016102378A1/en active Application Filing
-
2017
- 2017-06-20 CL CL2017001633A patent/CL2017001633A1/en unknown
- 2017-06-21 CO CONC2017/0006157A patent/CO2017006157A2/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2016102378A1 (en) | 2016-06-30 |
MY184085A (en) | 2021-03-17 |
CN107108691B (en) | 2021-06-29 |
JP2018505210A (en) | 2018-02-22 |
BR112017013398A2 (en) | 2018-03-06 |
MX2017007670A (en) | 2017-10-27 |
US20170342105A1 (en) | 2017-11-30 |
BR112017013398B1 (en) | 2023-12-05 |
IL252712B1 (en) | 2023-12-01 |
EP3237433A1 (en) | 2017-11-01 |
CA2969981A1 (en) | 2016-06-30 |
AU2015371341B2 (en) | 2021-05-20 |
AU2015371341A1 (en) | 2017-06-29 |
IL252712A0 (en) | 2017-08-31 |
US10626143B2 (en) | 2020-04-21 |
EA201791423A1 (en) | 2017-10-31 |
JP6807326B2 (en) | 2021-01-06 |
CO2017006157A2 (en) | 2017-09-20 |
IL252712B2 (en) | 2024-04-01 |
KR20170090510A (en) | 2017-08-07 |
CN107108691A (en) | 2017-08-29 |
EA039002B1 (en) | 2021-11-19 |
CA2969981C (en) | 2024-06-25 |
CL2017001633A1 (en) | 2017-11-24 |
KR102537099B1 (en) | 2023-05-25 |
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