SG11201703395PA - Methods and compositions relating to microbial treatment and diagnosis of disorders - Google Patents

Methods and compositions relating to microbial treatment and diagnosis of disorders

Info

Publication number
SG11201703395PA
SG11201703395PA SG11201703395PA SG11201703395PA SG11201703395PA SG 11201703395P A SG11201703395P A SG 11201703395PA SG 11201703395P A SG11201703395P A SG 11201703395PA SG 11201703395P A SG11201703395P A SG 11201703395PA SG 11201703395P A SG11201703395P A SG 11201703395PA
Authority
SG
Singapore
Prior art keywords
disorders
diagnosis
methods
microbial treatment
compositions relating
Prior art date
Application number
SG11201703395PA
Inventor
Colleen Cutcliffe
John S Eid
James H Bullard
Marcus F Schicklberger
Original Assignee
Whole Biome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Whole Biome Inc filed Critical Whole Biome Inc
Publication of SG11201703395PA publication Critical patent/SG11201703395PA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/733—Fructosans, e.g. inulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/145—Clostridium
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/605—Glucagons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
SG11201703395PA 2014-10-31 2015-10-30 Methods and compositions relating to microbial treatment and diagnosis of disorders SG11201703395PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462073912P 2014-10-31 2014-10-31
PCT/US2015/058511 WO2016070151A1 (en) 2014-10-31 2015-10-30 Methods and compositions relating to microbial treatment and diagnosis of disorders

Publications (1)

Publication Number Publication Date
SG11201703395PA true SG11201703395PA (en) 2017-05-30

Family

ID=55858436

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201903823QA SG10201903823QA (en) 2014-10-31 2015-10-30 Methods and compositions relating to microbial treatment and diagnosis of disorders
SG11201703395PA SG11201703395PA (en) 2014-10-31 2015-10-30 Methods and compositions relating to microbial treatment and diagnosis of disorders

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201903823QA SG10201903823QA (en) 2014-10-31 2015-10-30 Methods and compositions relating to microbial treatment and diagnosis of disorders

Country Status (8)

Country Link
US (11) US9486487B2 (en)
EP (2) EP3881680A1 (en)
JP (1) JP6868562B2 (en)
CN (2) CN108064132A (en)
CA (1) CA2964480A1 (en)
GB (1) GB2551642B (en)
SG (2) SG10201903823QA (en)
WO (1) WO2016070151A1 (en)

Families Citing this family (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US10314865B2 (en) 2011-02-04 2019-06-11 Katherine Rose Kovarik Method and system for treating cancer and other age-related diseases by extending the healthspan of a human
US9730967B2 (en) 2011-02-04 2017-08-15 Katherine Rose Kovarik Method and system for treating cancer cachexia
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
US11419903B2 (en) * 2015-11-30 2022-08-23 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US11273187B2 (en) * 2015-11-30 2022-03-15 Joseph E. Kovarik Method and system for reducing the likelihood of developing depression in an individual
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
CA2941694A1 (en) 2014-03-06 2015-09-11 Research Institute At Nationwide Children's Hospital Probiotic formulations and methods for use
US10624934B2 (en) 2014-03-06 2020-04-21 Research Institute At Nationwide Children's Hospital Prebiotic formulations
EP3209803A4 (en) 2014-10-21 2018-06-13 Ubiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics
US9710606B2 (en) 2014-10-21 2017-07-18 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues
GB2551642B (en) 2014-10-31 2020-09-23 Pendulum Therapeutics Inc Methods and compositions relating to microbial treatment and diagnosis of disorders
US10881674B2 (en) * 2014-12-08 2021-01-05 Glycom A/S Synthetic composition for treating metabolic disorders
PT3065748T (en) 2014-12-23 2018-02-28 4D Pharma Res Ltd A bacteroides thetaiotaomicron strain and its use in reducing inflammation
CA2970234A1 (en) 2014-12-23 2016-06-30 4D Pharma Research Limited Pirin polypeptide and immune modulation
US20160271189A1 (en) * 2015-03-18 2016-09-22 Whole Biome, Inc. Methods and compositions relating to microbial treatment and diagnosis of skin disorders
WO2016168370A1 (en) * 2015-04-14 2016-10-20 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions
CA2988693A1 (en) 2015-06-15 2016-12-22 4D Pharma Research Limited Compositions comprising bacterial strains
MA41060B1 (en) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprising bacterial strains
MA41010B1 (en) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprising bacterial strains
TWI759266B (en) 2015-06-15 2022-04-01 英商4D製藥研究有限公司 Use of compositions comprising bacterial strains
RS63089B1 (en) 2015-06-15 2022-04-29 4D Pharma Res Ltd Compositions comprising bacterial strains
US20180207067A1 (en) 2015-07-14 2018-07-26 Research Institute at Nationwide Children's Hospit al Novel formulation for the elimination of cariogenic and opportunistic pathogens within the oral cavity
EP3341082B1 (en) 2015-08-27 2020-12-16 PrecisionBiotics Group Limited Bifidobacterium longum
CN108348166B (en) 2015-09-09 2022-06-03 普梭梅根公司 Microbiota-derived diagnostic and therapeutic methods and systems for infectious diseases and other health conditions associated with antibiotic use
US9839655B2 (en) 2015-11-20 2017-12-12 4D Pharma Research Limited Compositions comprising bacterial strains
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
US11529412B2 (en) 2015-11-30 2022-12-20 Seed Health, Inc. Method and system for protecting honey bees from pesticides
US10086024B2 (en) 2015-11-30 2018-10-02 Joseph E. Kovarik Method and system for protecting honey bees, bats and butterflies from neonicotinoid pesticides
US10568916B2 (en) 2015-11-30 2020-02-25 Joseph E. Kovarik Method and system for protecting honey bees, bats and butterflies from neonicotinoid pesticides
US10933128B2 (en) 2015-11-30 2021-03-02 Joseph E. Kovarik Method and system for protecting honey bees from pesticides
US10675347B2 (en) 2015-11-30 2020-06-09 Joseph E. Kovarik Method and system for protecting honey bees from fipronil pesticides
JP2019500035A (en) * 2015-12-31 2019-01-10 カエルス ファーマシューティカルズ ビー．ヴィ． Method for culturing and preserving Eubacterium halli
CN106974940B (en) * 2016-01-15 2020-08-25 深圳华大生命科学研究院 Application of probiotics of scleritis in treating and preventing obesity and related diseases
PL3411052T3 (en) 2016-02-04 2021-03-08 Universiteit Gent Use of microbial communities for human and animal health
CN107080756B (en) * 2016-02-15 2020-08-25 深圳华大生命科学研究院 Use of probiotic bacteria of the genus streptococcus for the prevention and/or treatment of diabetes and related diseases
JP7327773B2 (en) 2016-03-04 2023-08-16 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Microbial communities and their uses
MX2018010680A (en) 2016-03-04 2019-06-13 4D Pharma Plc Compositions comprising bacterial blautia strains for treating visceral hypersensitivity.
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
JP7216998B2 (en) 2016-03-14 2023-02-02 ホロバイオーム， インコーポレイテッド Modification of the Gut Microbiome to Treat Central Nervous System Psychiatric Disorders or Diseases
RS64503B1 (en) 2016-04-15 2023-09-29 Baylor College Medicine Lactobacillus reuteri mm4-1a for use in the treatment or prevention of autism spectrum disorders
US9999641B2 (en) 2016-06-14 2018-06-19 Vedanta Biosciences, Inc. Treatment of clostridium difficile infection
KR101799829B1 (en) 2016-07-11 2017-11-21 한국생명공학연구원 Akkermansia muciniphila strain for preventing or treating degenerative brain disease and uses thereof
EP3483256A4 (en) * 2016-07-11 2019-12-04 Korea Research Institute of Bioscience and Biotechnology Akkermansia muciniphila strain having effect of preventing or treating degenerative brain diseases or metabolic diseases, and use thereof
TW201821093A (en) 2016-07-13 2018-06-16 英商４Ｄ製藥有限公司 Compositions comprising bacterial strains
CN109219656A (en) * 2016-09-06 2019-01-15 深圳华大生命科学研究院 Long dwell bacillus faecalis (Faecalibacterium longum) and its application
EP3526344B1 (en) * 2016-10-13 2020-09-30 Biomérieux Identification and antibiotic characterization of pathogens in metagenomic sample
IT201600109507A1 (en) * 2016-10-28 2018-04-28 Probiotical Spa COMPOSITION FOR THE PREVENTIVE OR CURATIVE TREATMENT OF LIVER DISORDERS
FR3059678A1 (en) * 2016-12-05 2018-06-08 Ecole Normale Superieure Lyon LACTIC ACID BACTERIA USEFUL IN TREATING METABOLIC DISEASES, IN PARTICULAR TYPE 2 DIABETES
EP3551201A4 (en) * 2016-12-06 2020-06-24 Pendulum Therapeutics, Inc. Methods and compositions relating to isolated and purified microbes
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
WO2018112209A1 (en) * 2016-12-14 2018-06-21 Warren Tracy System and methods for developing and using a microbiome-based action component for patient health
US11806372B2 (en) * 2017-04-21 2023-11-07 The Broad Institute, Inc. Methods of treating and diagnosing IBD associated with r. gnavus and/or r. gnavus group IBD colonization
MA48941A (en) 2017-05-22 2020-04-08 4D Pharma Res Ltd COMPOSITIONS CONTAINING BACTERIAL STRAINS
WO2018215782A1 (en) 2017-05-24 2018-11-29 4D Pharma Research Limited Compositions comprising bacterial strain
ES2917415T3 (en) 2017-06-14 2022-07-08 4D Pharma Res Ltd Compositions comprising a bacterial strain
ES2841902T3 (en) 2017-06-14 2021-07-12 4D Pharma Res Ltd Compositions comprising bacterial strains
JP2020529478A (en) * 2017-08-04 2020-10-08 セカンド ゲノム インコーポレイテッド ROSEBURIA HOMINIS as a biotherapeutic, Eubacterium Eligence, and combinations thereof
JP2020532515A (en) * 2017-08-30 2020-11-12 ペンデュラム セラピューティクス， インコーポレイテッド Methods and compositions for the treatment of microbiome-related disorders
EP3697230A4 (en) * 2017-10-18 2022-04-13 Native Microbials, Inc. Improving fowl production by administration of a synthetic bioensemble of microbes or purified strains thereof
KR20200128126A (en) 2018-03-02 2020-11-11 아카데미쉬 메디쉬 센트럼 Stool for the prevention or treatment of autoimmune diseases
WO2019172607A1 (en) * 2018-03-06 2019-09-12 주식회사 엠디헬스케어 Nanovesicles derived from coprococcus sp. bacteria, and use thereof
CN113038957A (en) 2018-04-10 2021-06-25 谢尔塔治疗公司 Microbial population
CN112236155A (en) * 2018-05-31 2021-01-15 深圳华大生命科学研究院 Composition and application thereof
CN112752579A (en) * 2018-06-25 2021-05-04 第二基因组股份有限公司 Anterostipes hadrus for promoting health
CN110638838B (en) * 2018-06-26 2021-07-06 瑞微（深圳）生物科技有限公司 Application of Ackermansia or prevotella in preparing medicine for enhancing anti-tumor immunity
EP3594321A1 (en) * 2018-07-10 2020-01-15 Université catholique de Louvain Dusodibacter, a novel bacterial genus of the gastroinstestinal microbiota and uses thereof
CA3106315A1 (en) * 2018-07-19 2020-01-23 Pendulum Therapeutics, Inc. Methods and compositions for microbial engraftment
CN108567799A (en) * 2018-08-01 2018-09-25 中国人民解放军总医院 A kind of full caprophyl complex capsule and its preparation method and application
AU2019349678A1 (en) * 2018-09-24 2021-04-15 Pendulum Therapeutics, Inc. Microbial compositions and methods of use
EP3646857A1 (en) * 2018-11-01 2020-05-06 Evonik Operations GmbH Colonic delivery system for microorganisms
BR112021008767A2 (en) * 2018-11-05 2021-08-17 The University Of Chicago methods and compositions for treating infectious, autoimmune and allergic disease
WO2020117997A1 (en) 2018-12-05 2020-06-11 The Procter & Gamble Company Container for personal health compositions
CN112867500B (en) * 2018-12-07 2023-08-01 深圳华大生命科学研究院 Use of human manure anaerobism coryneform bacteria in preventing and/or treating metabolic diseases
AU2019397458A1 (en) * 2018-12-11 2021-06-17 Glyciome, Llc Topical, isotonic compositions for genital use
EP3669944B1 (en) * 2018-12-21 2023-12-20 Salomon Amar Use of akkermansia in the treatment of oral diseases
US20200215127A1 (en) * 2019-01-09 2020-07-09 LifeBidge Health, Inc. Targeted synbiotic therapy for dysbiosis-related intestinal and extra-intestinal disorders
CN109666615B (en) * 2019-02-20 2021-03-19 无限极（中国）有限公司 Probiotic composition and application thereof
CN111991427A (en) * 2019-05-07 2020-11-27 瑞微（深圳）生物科技有限公司 Application of intestinal bacteria in preparation of medicine for promoting TCR gamma + T cell proliferation
US20220298111A1 (en) * 2019-08-09 2022-09-22 The Regents Of The University Of California Compositions and methods for treating metabolic disease
EP4025714A4 (en) * 2019-09-02 2023-10-11 My-Or Diagnostics Ltd. Skin microbiome monitoring for improving systemic health
CN112538439B (en) * 2019-09-04 2022-03-15 欧斐生 Lactobacillus plantarum and application thereof in preparing plant coagulated yoghurt and improving intestinal bacterial facies
KR20220108765A (en) 2019-10-07 2022-08-03 시올타 테라퓨틱스, 인크. therapeutic pharmaceutical composition
KR102136559B1 (en) * 2019-10-24 2020-07-22 건국대학교 산학협력단 Animal Food Composition and Feed Additive comprising Kefir
WO2021127494A2 (en) * 2019-12-20 2021-06-24 Pendulum Therapeutics, Inc. Methods and compositions comprising a bacteria with increased viability and faster revivability
IL271775A (en) * 2019-12-31 2021-06-30 Biomica Ltd Microbial consortium and uses thereof
IL294574A (en) * 2020-01-13 2022-09-01 Scioto Biosciences Inc Methods for treating or ameliorating autism and related disorders
WO2022163824A1 (en) * 2021-01-29 2022-08-04 アニコム ホールディングス株式会社 Method for predicting obesity
CN113046274B (en) * 2021-04-26 2022-09-27 江南大学 Lactobacillus reuteri for relieving gastrointestinal injury caused by capsaicin and application thereof
WO2023002461A1 (en) 2021-07-23 2023-01-26 Universidade Católica Portuguesa - Ucp Encapsulated bacterial, methods and uses thereof
CN114246886B (en) * 2021-12-24 2023-05-30 山西大学 Application of enterococcus faecalis in preparation for preventing and treating acute colitis
CN114774338B (en) * 2022-03-29 2023-08-08 北京航空航天大学 Probiotics for producing butyric acid, construction method and application thereof
EP4309662A1 (en) * 2022-07-19 2024-01-24 Enbiosis Biotechnology Limited Microorganisms converting inositol to butyrate
CN117106849B (en) * 2023-10-24 2024-02-02 山东省科霖检测有限公司 Urban air microorganism ecological distribution monitoring method

Family Cites Families (258)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1014986A (en) 1910-01-03 1912-01-16 Alfred J Ware Printing-machine.
US1014987A (en) 1910-12-12 1912-01-16 B L Shrader Gang-plow.
US3625214A (en) 1970-05-18 1971-12-07 Alza Corp Drug-delivery device
US4906474A (en) 1983-03-22 1990-03-06 Massachusetts Institute Of Technology Bioerodible polyanhydrides for controlled drug delivery
US4789734A (en) 1985-08-06 1988-12-06 La Jolla Cancer Research Foundation Vitronectin specific cell receptor derived from mammalian mesenchymal tissue
JP2876058B2 (en) 1986-08-18 1999-03-31 エミスフィア・テクノロジーズ・インコーポレイテッド Drug delivery system
US5143845A (en) * 1986-09-03 1992-09-01 Toa Pharmaceutical Co., Ltd. Mixture of saccarifying lactic acid producing and butyric acid producing bacteria
US5075109A (en) 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
US5811128A (en) 1986-10-24 1998-09-22 Southern Research Institute Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor
US4897268A (en) 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
US5443826A (en) 1988-08-02 1995-08-22 Borody; Thomas J. Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli
WO1990001335A1 (en) 1988-08-02 1990-02-22 Borody Thomas J Treatment of gastro-intestinal disorders
JP2961182B2 (en) 1990-03-09 1999-10-12 ミヤリサン株式会社 Pharmaceutical composition for prevention and treatment of Clostridium difficile diarrhea and pseudomembranous colitis
JP2961184B2 (en) 1990-05-07 1999-10-12 ミヤリサン株式会社 Pharmaceutical composition for prevention and treatment of Clostridium difficile diarrhea and pseudomembranous colitis
EP0678034B1 (en) 1993-01-11 1999-05-26 Dana Farber Cancer Institute Inducing cytotoxic t lymphocyte responses
GB9306473D0 (en) 1993-03-29 1993-05-19 Bioglan Lab Ltd Pharmaceutically useful compounds
US6241983B1 (en) 1994-10-28 2001-06-05 Metagenics, Inc. Bacteria-and fiber-containing composition for human gastrointestinal health
US5531989A (en) 1994-10-28 1996-07-02 Metagenics, Inc. Immunoglobulin and fiber-containing composition for human gastrointestinal health
JPH08298982A (en) * 1995-05-02 1996-11-19 Aasu Giken:Kk Complex microbial pharmaceutical preparation
WO1998018610A1 (en) 1996-10-28 1998-05-07 Lengerich Bernhard H Van Embedding and encapsulation of controlled release particles
US7767203B2 (en) * 1998-08-07 2010-08-03 Ganeden Biotech, Inc. Methods for the dietary management of irritable bowel syndrome and carbohydrate malabsorption
WO2000015760A1 (en) 1998-09-17 2000-03-23 North American Vaccine, Inc. Streptococcal c beta protein compositions
ATE290391T1 (en) 1998-12-11 2005-03-15 Urex Biotech Inc ORAL ADMINISTRATION OF LACTOBACILLUS FOR THE TREATMENT AND PREVENTION OF UROGENITAL INFECTIONS
ID29150A (en) 1999-01-15 2001-08-02 Entpr Ireland Cs USE OF LACTOBACILLUS SALIVARIUS
US7056661B2 (en) 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
ES2321797T3 (en) 1999-08-05 2009-06-12 Societe Des Produits Nestle S.A. BIFIDOBACTERIES THAT PREVENT THE DIARRHEA CAUSED BY PATHOGENIC BACTERIA.
JP4580542B2 (en) 2000-05-17 2010-11-17 株式會社バイオニア Microorganism for treating obesity or diabetes and pharmaceutical composition containing the microorganism
US20040062757A1 (en) 2001-06-05 2004-04-01 Finegold Sydney M. Method of testing gastrointestinal diseases associated with species of genus clostridium
US20040170617A1 (en) 2000-06-05 2004-09-02 Finegold Sydney M. Method of treating diseases associated with abnormal gastrointestinal flora
US20020013270A1 (en) 2000-06-05 2002-01-31 Bolte Ellen R. Method for treating a mental disorder
FI110668B (en) 2000-06-20 2003-03-14 Aboatech Ab Oy Use of probiotics for primary prevention of atopic diseases
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
DE10043151A1 (en) * 2000-08-31 2002-03-28 Peter Steinruecke Bone cement with antimicrobial effectiveness
EP1227152A1 (en) 2001-01-30 2002-07-31 Société des Produits Nestlé S.A. Bacterial strain and genome of bifidobacterium
IL157071A0 (en) 2001-02-06 2004-02-08 Nestle Sa Endotoxine binding by lactic acid bacteria and bifidobacteria
WO2002085415A1 (en) 2001-04-17 2002-10-31 Biomatrix, Inc Non-digestible sugar-coated products and process
US7101565B2 (en) 2002-02-05 2006-09-05 Corpak Medsystems, Inc. Probiotic/prebiotic composition and delivery method
US20050069505A1 (en) 2002-02-21 2005-03-31 Lionel Breton Orally administrable composition for the photoprotection of the skin
ITBO20020564A1 (en) 2002-09-06 2004-03-07 Alfa Wassermann Spa BIFIDOBACTERIA AND PREPARATIONS THAT CONTAIN THEM.
SE526711C2 (en) 2003-01-31 2005-10-25 Probi Ab Novel strains of Bifidobacterium having ability to survive in intestinal tract and produce glutamine and arginine in vivo, useful for preparing medicament for treatment of intensive care patients with intestinal failure
CA2559596A1 (en) 2003-03-13 2004-11-25 Universite De Moncton (Bureau De Soutien A L'innovation) Antioxidant producing bacterium and uses thereof
GB0307026D0 (en) 2003-03-27 2003-04-30 Rowett Res Inst Bacterial supplement
EP1462116A1 (en) 2003-03-29 2004-09-29 Villitech SARL Composition for treating the gastrointestinal tract
US8192733B2 (en) 2003-08-29 2012-06-05 Cobb & Associates Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions
US20050100559A1 (en) 2003-11-07 2005-05-12 The Procter & Gamble Company Stabilized compositions comprising a probiotic
EP1600060A1 (en) 2004-05-25 2005-11-30 Cognis IP Management GmbH Oral and/or topical compositions comprising prebiotics and fatty acid
AU2005257033B2 (en) 2004-06-23 2011-05-12 L'oreal Method and compositions useful for preventing and/or treating sensitive and/or dry skin
CA2471142A1 (en) 2004-06-25 2005-12-25 Pierre Marcotte Spring with controlled behaviour
US7862808B2 (en) 2004-07-01 2011-01-04 Mead Johnson Nutrition Company Method for preventing or treating respiratory infections and acute otitis media in infants using Lactobacillus rhamnosus LGG and Bifidobacterium lactis Bb-12
ITMI20041550A1 (en) 2004-07-29 2004-10-29 Proge Farm Srl USE OF PROBIOTIC BACTERIA FOR THE PREPARATION OF TOPICAL COMPOSITIONS FOR THE PROTECTION OF THE EPIDERMIS
FR2874825B1 (en) 2004-09-08 2006-12-08 Genibio Sarl USES OF BENEFICIAL PREBIOTIC OLIGOSACCHARIDES FOR VAGINAL FLORA
US20060115465A1 (en) 2004-10-29 2006-06-01 Macfarlane George Treatment of gastrointestinal disorders
EP1812068A4 (en) 2004-10-29 2010-06-09 Medimmune Inc Methods of preventing and treating rsv infections and related conditions
JP5565991B2 (en) 2004-12-15 2014-08-06 株式会社島津製作所 Microbe species estimation system and method
KR101102914B1 (en) 2004-12-28 2012-01-10 메이지 세이카 파루마 가부시키가이샤 Novel strain conferring anti-disease properties to host and bacterial cell composition
TW200700074A (en) 2005-03-04 2007-01-01 Calpis Co Ltd Inducer of t cell apoptosis
US20060223153A1 (en) 2005-04-05 2006-10-05 Luca Technologies, Llc Generation of materials with enhanced hydrogen content from anaerobic microbial consortia
EP1877565A4 (en) 2005-05-03 2011-11-16 Anaerobe Systems Anaerobic production of hydrogen and other chemical products
JP2006314219A (en) * 2005-05-11 2006-11-24 Asahi Breweries Ltd Method for adsorbing bile acid utilizing enterobacterium, and bile acid-adsorbing substance
JP2007031291A (en) * 2005-07-22 2007-02-08 Ace Bio Product Kk Body weight increase-inhibiting agent and body weight increase-inhibiting drink
FR2889958A1 (en) 2005-08-25 2007-03-02 Lyoct Sa Lab USE OF A SYMBIOTIC FOR THE TREATMENT OF ATOPIC DERMATITIS
EP1776877A1 (en) 2005-10-21 2007-04-25 N.V. Nutricia Method for stimulating the intestinal flora
MX2008009726A (en) * 2006-01-27 2009-03-05 Danisco Use.
ITRM20060237A1 (en) 2006-05-03 2007-11-04 Anabasis S R L USE OF PROBIOTICS IN THE PREVENTION AND TREATMENT OF ALLERGIC CONJUNCTIVES
ATE526962T1 (en) 2006-05-18 2011-10-15 Biobalance Llc BIOTHERAPEUTIC COMPOSITION CONTAINING PROBIOTIC ESCHERICHIA COLI AND METRONIDAZOLE AND USES THEREOF
CN1850047A (en) 2006-06-01 2006-10-25 济南帅华医药科技有限公司 Slow-release preparation containing beta-lactamase inhibitor and cephalosporin and its use
JP5019563B2 (en) 2006-06-16 2012-09-05 旭化成ケミカルズ株式会社 Intestinal bacteria activator
CN101095698B (en) 2006-06-26 2010-12-01 青岛东海药业有限公司 Use of Clostridium Butyricum for preventing and treating foetid faeces toxin syndrome and disease
US7867578B2 (en) * 2006-06-28 2011-01-11 Applied Materials, Inc. Method for depositing an amorphous carbon film with improved density and step coverage
US20080069861A1 (en) 2006-09-19 2008-03-20 National Starch And Chemical Investment Holding Corporation Probiotic/Non-Probiotic Combinations
WO2008076696A2 (en) 2006-12-18 2008-06-26 Washington University In St. Louis The gut microbiome as a biomarker and therapeutic target for treating obesity or an obesity related disorder
US20110020283A1 (en) 2007-02-22 2011-01-27 Schrezenmeir Juergen Probiotic, gram-positive bacteria for the prophylaxis, suppression, or elimination of allergic reactions in humans
US9644210B2 (en) 2007-02-22 2017-05-09 Jürgen Schrezenmeir Probiotic gram-positive bacteria for the prophylaxis, suppression, or elimination of allergic reactions in human
KR20100016012A (en) 2007-03-28 2010-02-12 앨러멘터리 헬스 리미티드 Probiotic bifidobacterium strains
AU2008231467A1 (en) 2007-03-28 2008-10-02 Alimentary Health Limited Probiotic Bifidobacterium strains
CA2684713C (en) 2007-05-03 2019-02-19 Tobias Olofsson Lactobacillus or bifidobacterium isolated from honey or honey producing tracts of honey bees
TW200904340A (en) 2007-05-11 2009-02-01 Mannatech Inc Processing of natural polysaccharides by selected non-pathogenic microorganisms and methods of making and using the same
EP1992351B1 (en) 2007-05-18 2016-05-11 Nestec S.A. Lactobacillus johnsonii for prevention of postsurgical infection
US20090010892A1 (en) * 2007-07-06 2009-01-08 Toa Pharmaceutical Co., Ltd. Hyperlipidemia Treatment Agent
US20090010891A1 (en) * 2007-07-06 2009-01-08 Toa Pharmaceutical Co., Ltd. Sepsis Treatment Agent
WO2009018447A2 (en) 2007-07-31 2009-02-05 New York University Diagnostic and treatment methods for characterizing bacterial microbiota in skin conditions
EP2030623A1 (en) 2007-08-17 2009-03-04 Nestec S.A. Preventing and/or treating metabolic disorders by modulating the amount of enterobacteria
WO2009043856A2 (en) 2007-10-01 2009-04-09 University College Cork, National University Of Ireland, Cork Modulation of tissue fatty acid composition of a host by human gut bacteria
US8478544B2 (en) 2007-11-21 2013-07-02 Cosmosid Inc. Direct identification and measurement of relative populations of microorganisms with direct DNA sequencing and probabilistic methods
EP2072052A1 (en) 2007-12-17 2009-06-24 Nestec S.A. Prevention of opportunistic infections in immune-compromised subjects
ES2343499B1 (en) 2007-12-24 2011-06-10 Consejo Superior De Investigaciones Cientificas MICROORGANISMS TO IMPROVE THE STATE OF HEALTH OF INDIVIDUALS WITH DISORDERS RELATED TO THE INTAKE OF GLUTEN.
EP2110028A1 (en) 2008-04-15 2009-10-21 Nestec S.A. Bifidobacterium longum and hippocampal BDNF expression
US20110189149A1 (en) 2008-06-20 2011-08-04 Remy Burcelin New Uses of Lactic Acid Bacteria and Bifidobacteria
WO2010003916A1 (en) 2008-07-11 2010-01-14 Chr. Hansen A/S New probiotic bifidobacterium longum
US8569466B2 (en) 2008-09-10 2013-10-29 Nnochiri Ekwuribe Aromatic carboxylic acid derivatives for treatment and prophylaxis of gastrointestinal diseases including colon cancers
US9603876B2 (en) 2008-09-25 2017-03-28 New York University Compositions and methods for restoring gastrointestinal microbiota following antibiotic treatment
WO2010040055A2 (en) 2008-10-03 2010-04-08 Intekrin Therapeutics, Inc. Oral pharmaceutical formulations for antidiabetic compounds
CN102984955B (en) 2008-11-11 2015-01-07 营养健康有限公司 Bifidobacterium longum
JP5606672B2 (en) 2008-11-26 2014-10-15 太陽化学株式会社 Intestinal environment adjustment method using symbiotics
WO2010096550A2 (en) 2009-02-18 2010-08-26 University Of Florida Research Foundation, Inc. Lactobacillus supplement for alleviating type 1 diabetes
KR20190000937A (en) * 2009-02-24 2019-01-03 리터 파마슈티컬즈 인코오포레이티드 Prebiotic formulations and methods of use
US20100086981A1 (en) 2009-06-29 2010-04-08 Qteros, Inc. Compositions and methods for improved saccharification of biomass
DK2411027T3 (en) * 2009-03-25 2015-01-19 Chr Hansen As USING a probiotic ADJUSTING body weight
EP2411026A1 (en) 2009-03-25 2012-02-01 Chr. Hansen A/S Use of probiotics to ameliorate diet-induced insulin resistance
CA2761150C (en) 2009-05-07 2017-06-13 Tate & Lyle Ingredients France SAS Compositions and methods for making alpha-(1,2)-branched alpha-(1,6) oligodextrans
US10576110B2 (en) 2009-05-11 2020-03-03 Societe Des Produits Nestle S.A. Lactobacillus johnsonii La1 NCC533 (CNCM I-1225) and immune disorders
CN102458415B (en) 2009-06-19 2015-05-20 杜邦营养生物科学有限公司 Bifidobacteria for treating diabetes and related conditions
US20150320808A1 (en) 2009-06-19 2015-11-12 Dupont Nutrition Biosciences Aps Bifidobacteria for treating cardiac conditions
US9848760B2 (en) 2009-06-29 2017-12-26 Gearbox, Llc Devices for continual monitoring and introduction of gastrointestinal microbes
WO2011011094A1 (en) 2009-07-24 2011-01-27 Dowd Scot E Universal microbial diagnosis, detection, quantification, and specimen-targeted therapy
CN102470152A (en) 2009-07-30 2012-05-23 丹尼斯科公司 Lactic acid bacteria and bifidobacteria for treating endotoxemia
DK2289527T3 (en) 2009-08-25 2018-04-23 Nestec Sa BIFIDOBACTERIUM LONGUM AND FUNCTIONAL GI DISEASES
EP2486143A1 (en) 2009-10-05 2012-08-15 AAK Patent B.V. Methods for diagnosing irritable bowel syndrome
US20110081320A1 (en) 2009-10-06 2011-04-07 Nubiome, Inc. Treatment/Cure of Autoimmune Disease
KR100962365B1 (en) 2009-10-07 2010-06-10 주식회사 대일 A container for transport of live-fish
EP2498626B1 (en) 2009-11-12 2015-06-17 Nestec S.A. Nutritional composition for promoting gut microbiota balance and health
WO2011073769A2 (en) 2009-12-16 2011-06-23 Probiotical S.P.A. Conjugated linoleic acid-producing strains of probiotic bacteria and use thereof for the preparation of a food, dietetic or pharmaceutical composition
US9504750B2 (en) 2010-01-28 2016-11-29 Advanced Bionutrition Corporation Stabilizing composition for biological materials
NL2004201C2 (en) 2010-02-05 2011-08-08 Friesland Brands Bv Use of sialyl oligosaccharides to modulate the immune system.
WO2011099514A1 (en) 2010-02-10 2011-08-18 日環科学株式会社 Mixture, dissolving solution and pharmaceutical agent each comprising thermophilic microorganism
JP2013520972A (en) 2010-03-01 2013-06-10 アンスティテュ ナシオナル ドゥ ラ ルシェルシュ アグロノミック Diagnosis method of inflammatory bowel disease
US20130005586A1 (en) 2010-03-01 2013-01-03 Stanislav Ehrlich Method of diagnostic of obesity
IT1398553B1 (en) 2010-03-08 2013-03-01 Probiotical Spa COMPOSITION INCLUDING PROBIOTIC BACTERIA FOR THE TREATMENT OF PATHOLOGIES ASSOCIATED WITH THE ALTERATION OF THE IMMUNE SYSTEM.
KR101690616B1 (en) * 2010-04-12 2016-12-28 엘지전자 주식회사 A method and apparatus for efficient feedback in a wireless communication system supporting multiple antenna
WO2011137249A1 (en) 2010-04-28 2011-11-03 Ritter Pharmaceuticals, Inc. Prebiotic formulations and methods of use
FI20105478A0 (en) 2010-04-30 2010-04-30 Valtion Teknillinen Procedure for Diagnosing Type 1 Diabetes and Procedures and Compositions for Preventing Type 1 Diabetes Outbreak
US8951512B2 (en) 2010-05-04 2015-02-10 New York University Methods for treating bone disorders by characterizing and restoring mammalian bacterial microbiota
WO2011151941A1 (en) 2010-06-04 2011-12-08 国立大学法人東京大学 Composition having activity of inducing proliferation or accumulation of regulatory t cell
WO2012002322A1 (en) 2010-06-28 2012-01-05 株式会社ヤクルト本社 Skin properties improving agent for oral administration
US9192554B2 (en) 2010-06-30 2015-11-24 Nestec S.A. Use of chicoric acid and lactic bacterium in food supplement for regulating skin pigmentation
US20130143288A1 (en) * 2010-08-12 2013-06-06 The Administrators Of The Tulane Educational Fund Isolated bacteria, methods for use, and methods for isolation
US9386793B2 (en) 2010-08-20 2016-07-12 New York University Compositions and methods for treating obesity and related disorders by characterizing and restoring mammalian bacterial microbiota
CA2811056A1 (en) 2010-09-10 2012-03-15 Viropharma Incorporated Environmental clostridial bacteriotherapy and related formulations and methods of manufacture and use
EP2944690B1 (en) 2010-10-11 2017-12-20 Jennewein Biotechnologie GmbH Novel fucosyltransferases and their applications
US20120165792A1 (en) 2010-12-22 2012-06-28 Ethicon Endo-Surgery, Inc. Pill Catchers
EP2658559A1 (en) * 2010-12-29 2013-11-06 Nestec S.A. Fiber and probiotics for reducing intestinal symptoms related to stress
US10245288B2 (en) 2011-02-04 2019-04-02 Joseph E. Kovarik Method and system for reducing the likelihood of developing NASH in an individual diagnosed with non-alcoholic fatty liver disease
CN111518866A (en) 2011-03-01 2020-08-11 群体创新有限责任公司 Materials and methods for treating conditions associated with pathogenic biofilms
EP4129312A1 (en) 2011-03-09 2023-02-08 Regents Of The University Of Minnesota Compositions and methods for transplantation of colon microbiota
WO2012142605A1 (en) 2011-04-15 2012-10-18 Samaritan Health Services Rapid recolonization deployment agent
CN102254089A (en) 2011-04-18 2011-11-23 王钰 System simulating method and system
ITMI20110793A1 (en) 2011-05-09 2012-11-10 Probiotical Spa STRAINS OF PROBIOTIC BACTERIA AND SYNBIOTIC COMPOSITION CONTAINING THEMSELVES INTENDED FOR THE BABY FOOD.
EP2797606A4 (en) 2011-08-17 2015-09-30 MicroBiome Therapeutics LLC Composition and use of a formulation to increase the ratio of gastrointestinal microbiota in phylum bacteriodites to microbiota of firmuctes phylum
US9493737B2 (en) 2011-08-18 2016-11-15 Chr. Hansen A/S Method for purifying bacterial cells
SG11201401811WA (en) 2011-08-30 2014-09-26 Amc Amsterdam Method for preventing and/or treating insulin resistance
ES2662793T3 (en) 2011-09-14 2018-04-09 Nubiyota Llc Media supplements and methods for growing human gastrointestinal anaerobic microorganisms
US20130121968A1 (en) 2011-10-03 2013-05-16 Atossa Genetics, Inc. Methods of combining metagenome and the metatranscriptome in multiplex profiles
GB201117313D0 (en) * 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
FI20116008A0 (en) 2011-10-12 2011-10-12 Maeyrae Maekinen Annika Prevention and diagnosis of visceral fat
US9649346B2 (en) 2011-11-02 2017-05-16 Bios Llc Probiotic stick formulation for skin maintenance and methods of use
KR20140093252A (en) 2011-11-04 2014-07-25 제네랄밀즈인코포레이팃드 Methods and compositions for modulating gastrointestinal bacteria to promote health
EP3978598A1 (en) 2011-12-01 2022-04-06 The University of Tokyo Human-derived bacteria that induce proliferation or accumulation of regulatory t cells
MY172363A (en) 2011-12-07 2019-11-21 Asahi Group Holdings Ltd Lipid metabolism and/or sugar metabolism improver containing lactic acid bacterium or treatment product thereof
ES2659947T3 (en) 2012-01-19 2018-03-20 University College Cork-National University Of Ireland, Cork Cultivable GABA producing bacteria derived from the human gastrointestinal tract
US9173910B2 (en) 2012-02-29 2015-11-03 The General Hospital Corporation Compositions of microbiota and methods related thereto
ES2436251B1 (en) 2012-05-25 2014-10-08 Consejo Superior De Investigaciones Científicas (Csic) BACTEROIDS CECT 7771 AND ITS USE IN THE PREVENTION AND TREATMENT OF OVERWEIGHT, OBESITY AND METABOLIC AND IMMUNOLOGICAL ALTERATIONS.
US20130344042A1 (en) 2012-06-20 2013-12-26 Gretchen Tanbonliong Dietary management of celiac disease and food allergy
WO2014011233A1 (en) * 2012-07-09 2014-01-16 Trachtman Ira Milton Compositions and method for treatment and prophylaxis of inflammatory bowel disease
EP2885396B1 (en) 2012-08-20 2020-02-19 Chr. Hansen A/S Method for optimizing a process for freeze drying a bacteria-containing concentrate
CA3092314A1 (en) * 2012-09-20 2014-03-27 Prothera, Inc. Probiotic compositions and methods for the treatment of obesity and obesity-related conditions
AU2013338774B2 (en) 2012-11-01 2017-03-02 Academisch Ziekenhuis Groningen Methods and compositions for stimulating beneficial bacteria in the gastrointestinal tract
WO2014075745A1 (en) * 2012-11-19 2014-05-22 Université Catholique de Louvain Use of akkermansia for treating metabolic disorders
EP2919796B1 (en) 2012-11-19 2021-04-28 Université catholique de Louvain Use of akkermansia for treating metabolic disorders
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
DK3628161T3 (en) 2012-11-23 2023-05-30 Seres Therapeutics Inc Synergistic bacterial compositions and methods of making and using the same
WO2014088982A1 (en) 2012-12-07 2014-06-12 Albert Einstein College Of Medicine Of Yeshiva University Gut barrier dysfunction treatment and prevention
WO2014121304A1 (en) 2013-02-04 2014-08-07 Seres Health, Inc. Compositions and methods
WO2014121301A1 (en) 2013-02-04 2014-08-07 Seres Health, Inc. Compositions and methods for inhibition of pathogenic bacterial growth
AU2014226633A1 (en) 2013-03-05 2015-09-03 Academisch Ziekenhuis Groningen Use of Faecali bacterium prausnitzii HTF-F (DSM 26943) to suppress inflammation.
CN110075130A (en) * 2013-03-14 2019-08-02 塞拉拜姆有限责任公司 The delivering of the targeting gastrointestinal tract of probiotics and/or therapeutic agent
US20160040215A1 (en) 2013-03-14 2016-02-11 Seres Therapeutics, Inc. Methods for Pathogen Detection and Enrichment from Materials and Compositions
US10716802B2 (en) 2013-03-15 2020-07-21 The Brigham And Women's Hospital, Inc. Compounds to modulate intestinal absorption of nutrients
AU2014232370B2 (en) 2013-03-15 2018-11-01 Seres Therapeutics, Inc. Network-based microbial compositions and methods
WO2014190251A1 (en) 2013-05-24 2014-11-27 Genomatica, Inc. Microorganisms and methods for producing (3r)-hydroxybutyl (3r)-hydroxybutyrate
US20160120915A1 (en) 2013-06-10 2016-05-05 New York University Methods for manipulating immune responses by altering microbiota
KR101470513B1 (en) 2013-07-17 2014-12-08 주식회사 아모그린텍 Soft Magnetic Cores Having Excellent DC Biased Characteristics in High Current and Core Loss Characteristics, and Manufacturing Methods thereof
US10633714B2 (en) 2013-07-21 2020-04-28 Pendulum Therapeutics, Inc. Methods and systems for microbiome characterization, monitoring and treatment
CA2926466C (en) 2013-10-03 2021-11-16 Frederic Bushman Compositions comprising a defined microbiome and methods of use thereof
US10058576B2 (en) 2013-10-03 2018-08-28 The Trustees Of The University Of Pennsylvania Compositions and methods comprising a defined microbiome and methods of use thereof
EP3060656A1 (en) 2013-10-24 2016-08-31 Yeda Research and Development Co., Ltd. Polynucleotides encoding brex system polypeptides and methods of using same
GB201319531D0 (en) 2013-11-05 2013-12-18 Optibiotix Health Ltd Composition & methods of screening
GB201319525D0 (en) 2013-11-05 2013-12-18 Optibiotix Health Ltd Composition
GB201319539D0 (en) 2013-11-05 2013-12-18 Optibiotix Health Ltd Composition & methods of screening
GB201319538D0 (en) 2013-11-05 2013-12-18 Optibiotix Health Ltd Composition
GB201319540D0 (en) 2013-11-05 2013-12-18 Optibiotix Health Ltd Composition
WO2015077794A1 (en) 2013-11-25 2015-05-28 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
KR20150066772A (en) 2013-12-09 2015-06-17 주식회사 쎌바이오텍 A novel lactic acid bacteria and composition for preventing or treating diarrhea of an infant comprising the same
EP3082431A4 (en) 2013-12-16 2017-11-15 Seres Therapeutics, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
JP6527522B2 (en) 2013-12-20 2019-06-05 ネステク ソシエテ アノニム Nutritional composition for reducing enteric pathogens
WO2015089674A1 (en) 2013-12-20 2015-06-25 9286-3620 Québec Inc. Protein-based enteric coating for oral dosage forms
EP3102670A4 (en) 2014-02-04 2017-07-12 Micro-nature LLC Systems, methods, and compositions relating to combiomics
US20160354509A1 (en) 2014-02-10 2016-12-08 The Johns Hopkins University Devices for and methods of treatment of metabolic syndromes
US20160354418A1 (en) 2014-02-14 2016-12-08 Vesale Pharma Sa Use of compositions comprising bifidobacterium animalis ssp. lactis lmg p-28149
US20160367661A1 (en) 2014-02-27 2016-12-22 Yale University NLRP6 Inflammasome Intestinal Epithelium Mucus Secretion
US20150246081A1 (en) 2014-03-03 2015-09-03 Shayne Kenneth Morris Probiotics with methods for growth and use separately and in combination
US20150374760A1 (en) 2014-04-09 2015-12-31 Jose U. Scher Methods for treating psoriasis and psoriatic arthritis
CN111768837A (en) 2014-04-28 2020-10-13 耶达研究及发展有限公司 Method and apparatus for predicting reaction to food
CN106460048B (en) 2014-04-28 2021-01-05 耶达研究及发展有限公司 Microbiome response to agents
FI127483B (en) 2014-06-11 2018-07-13 Gut Guide Oy Microbiomarker for celiac disease and a related product
MX2014009044A (en) 2014-07-25 2016-01-25 Polioles S A De C V Novel molecules derived from phosphorylated 2-phenyl-imidazolines , having high imidazoline ring stability and a high level of effectiveness as corrosion inhibitors.
MX2017002155A (en) 2014-08-18 2017-05-01 Nestec Sa Prebiotics for reducing the risk of obesity later in life.
US10410749B2 (en) 2014-10-21 2019-09-10 uBiome, Inc. Method and system for microbiome-derived characterization, diagnostics and therapeutics for cutaneous conditions
US9710606B2 (en) 2014-10-21 2017-07-18 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues
US9760676B2 (en) 2014-10-21 2017-09-12 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions
CN107249611A (en) 2014-10-24 2017-10-13 进化生物系统股份有限公司 The Bifidobacterium of activation and its application process
WO2016065419A1 (en) 2014-10-28 2016-05-06 Medlab Ip Pty Ltd Treatment for depression and depressive disorders
GB2551642B (en) * 2014-10-31 2020-09-23 Pendulum Therapeutics Inc Methods and compositions relating to microbial treatment and diagnosis of disorders
US20190102512A1 (en) 2014-11-17 2019-04-04 Yeda Research And Development Co., Ltd. Method of analyzing microbiome
MA41020A (en) 2014-11-25 2017-10-03 Evelo Biosciences Inc PROBIOTIC AND PREBIOTIC COMPOSITIONS, AND THEIR METHODS OF USE FOR MODULATION OF THE MICROBIOME
CN109496234A (en) 2014-11-26 2019-03-19 波比奥泰克股份公司 For maintaining the lactobacillus of stable state and the bacterial strain of Bifidobacterium
US9688967B2 (en) 2014-12-05 2017-06-27 Synlogic, Inc. Bacteria engineered to treat diseases associated with hyperammonemia
US20160206666A1 (en) 2014-12-22 2016-07-21 Synlogic, Inc. Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tighten gut mucosal barrier
EP3242957B1 (en) 2015-01-09 2020-03-11 Wageningen Universiteit Bacteria-comprising compositions and methods of using the same for treating and/or preventing gastrointestinal, metabolic and/or other diseases
KR20170128247A (en) 2015-01-23 2017-11-22 템플 유니버시티-오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 Use of short-chain fatty acids in cancer prevention
WO2016139217A1 (en) 2015-03-04 2016-09-09 Ab-Biotics, S.A. Composition comprising anaerobically cultivated human intestinal microbiota
MX2017011669A (en) 2015-03-13 2017-11-06 Evolve Biosystems Inc Compositions that metabolize or sequester free sugar monomers and uses thereof.
US20160271189A1 (en) 2015-03-18 2016-09-22 Whole Biome, Inc. Methods and compositions relating to microbial treatment and diagnosis of skin disorders
WO2016176380A1 (en) 2015-04-28 2016-11-03 The Procter & Gamble Company Compositions comprising whole, non-viable micrococcus for improving skin health
EP3289093A4 (en) 2015-04-28 2019-04-17 Yeda Research and Development Co., Ltd. Use of microbial metabolites for treating diseases
WO2016177797A1 (en) 2015-05-06 2016-11-10 Wageningen Universiteit Use of a polypeptide for effecting immune signalling and/or affecting intestinal barrier function and/or modulating metabolic status
AU2016258976B2 (en) 2015-05-06 2021-02-25 Wageningen Universiteit Method of culturing Akkermansia
KR101589466B1 (en) 2015-05-21 2016-02-01 주식회사 쎌바이오텍 Use of bifidobacterium longum cbt bg7 strain for promoting growth and nutraceutical composition for promoting growth comprising the same
KR101589464B1 (en) 2015-05-21 2016-02-01 주식회사 쎌바이오텍 New bifidobacterium strain and nutraceutical composition for improving growth comprising the same
EP3297727A1 (en) 2015-05-21 2018-03-28 Yeda Research and Development Co. Ltd Bacterial populations for promoting health
US20180140645A1 (en) 2015-05-30 2018-05-24 Japan Eco-Science Co., Ltd. Probiotic or prebiotic, method for producing same, microbial preparation, health food, and medicine
EP3915552A1 (en) 2015-06-01 2021-12-01 Xeno Biosciences Inc. Compositions for use in modulating the gut microbiota and managing weight
US20160355847A1 (en) 2015-06-03 2016-12-08 The United States Of America, As Represented By The Secretary Of Agriculture Novel Clostridium Species That Converts Wheat Straw and Switchgrass Hydrolysates Into Butyric Acid
EP3307906B1 (en) 2015-06-09 2020-10-14 Regents of the University of Minnesota Methods for detecting risk of having a bloodstream infection
GB201514303D0 (en) 2015-07-16 2015-09-23 Dupont Nutrition Biosci Aps Bifidobacteria for treating cardiac conditions
EP3328215B1 (en) 2015-07-29 2021-07-07 Advanced BioNutrition Corp. Stable dry probiotic compositions for special dietary uses
EP3331499A4 (en) 2015-08-06 2019-04-10 The Johns Hopkins University Composition and method for treatment of metabolic disorders
US10300043B2 (en) 2015-08-12 2019-05-28 Mayo Foundation For Medical Education And Research Method for treating a gastrointestinal disorder in a mammal using bacteroides thetaiotaomicron and compositions thereof
CN105030841A (en) 2015-08-24 2015-11-11 上海交通大学医学院附属瑞金医院 Application of Akkermansia muciniphila BAA-835 strain
JP7088827B2 (en) 2015-08-24 2022-06-21 ニューバイヨタ エルエルシー Treatment system and method for dysbiosis using fecal-derived bacterial population
CN105106245A (en) 2015-08-24 2015-12-02 上海交通大学医学院附属瑞金医院 Application of Akkermansia muciniphila BAA-835 bacterial strain
WO2017035412A1 (en) 2015-08-25 2017-03-02 Kaleido Biosciences, Inc. Glycan compositions and uses thereof
EP3341082B1 (en) 2015-08-27 2020-12-16 PrecisionBiotics Group Limited Bifidobacterium longum
EP3341081B1 (en) 2015-08-27 2020-11-11 PrecisionBiotics Group Limited Use of bifidobacterium longum and an exopolysaccharide produced thereby
WO2017041039A1 (en) 2015-09-04 2017-03-09 Memorial Sloan-Kettering Cancer Center Methods and compositions for detecting risk of cancer relapse
PT3626081T (en) 2015-09-10 2022-02-25 Univ Catholique Louvain Pasteurized akkermansia for promoting weight loss
WO2017047968A1 (en) 2015-09-15 2017-03-23 경희대학교 산학협력단 Novel lactobacillus having various functions, and use thereof
JP2018534277A (en) 2015-10-05 2018-11-22 シュヴァイツェリッシェ フォルシュングスインスティテュート フュア ホーフゲブリクスクリーマ ウント メディツィン イン ダヴォス Use of Akkermansia muciniphila for treating inflammatory conditions
WO2017060468A1 (en) 2015-10-07 2017-04-13 Galderma Research & Development Composition containing lactic acid bacteria and its use to treat atopic dermatitis
BR112018007560A2 (en) 2015-10-15 2018-10-23 Natura Cosméticos S.A. cosmetic composition having probiotic bacteria
EP3368050A1 (en) 2015-10-26 2018-09-05 Crestovo Holdings LLC Compositions and methods for fecal microbiota-related therapy
IL298281A (en) 2015-11-03 2023-01-01 Brigham & Womens Hospital Inc Therapeutic microbiota for the treatment and/or prevention of food allergy
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
AU2016359178A1 (en) 2015-11-24 2018-06-14 Seres Therapeutics, Inc. Designed bacterial compositions
US9668991B1 (en) 2015-12-09 2017-06-06 International Business Machines Corporation SCFA colonic composition
BR112018011665A2 (en) 2015-12-11 2018-12-04 Alimentary Health Ltd bifidobacterium longum for the treatment of obesity and associated metabolic disorders
US10548844B2 (en) 2015-12-14 2020-02-04 Massachusetts Institute Of Technology pH-responsive mucoadhesive polymeric encapsulated microorganisms
RU2743405C2 (en) 2015-12-14 2021-02-18 Метабоген Аб Treatment of intrahepatic cholestasis and related liver diseases
JPWO2017130859A1 (en) 2016-01-28 2018-11-15 森永乳業株式会社 Nerve cell death inhibitor
PL3411052T3 (en) 2016-02-04 2021-03-08 Universiteit Gent Use of microbial communities for human and animal health
WO2017146580A1 (en) 2016-02-25 2017-08-31 Caelus Pharmaceuticals B.V. Compositions and methods for preventing and/or treating vitamin b12 deficiency
EP3431089A4 (en) 2016-03-14 2020-04-15 B Food Science Co., Ltd. Agent for increasing intestinal butyric acid and proliferation agent for butyric acid-producing bacteria
EP3551201A4 (en) 2016-12-06 2020-06-24 Pendulum Therapeutics, Inc. Methods and compositions relating to isolated and purified microbes
US20180357375A1 (en) 2017-04-04 2018-12-13 Whole Biome Inc. Methods and compositions for determining metabolic maps
CN111212655A (en) 2017-08-14 2020-05-29 赛里斯治疗公司 Compositions and methods for treating cholestatic diseases
JP2020532515A (en) 2017-08-30 2020-11-12 ペンデュラム セラピューティクス， インコーポレイテッド Methods and compositions for the treatment of microbiome-related disorders
AU2019349678A1 (en) 2018-09-24 2021-04-15 Pendulum Therapeutics, Inc. Microbial compositions and methods of use
JP2022533672A (en) 2019-05-21 2022-07-25 ペンデュラム セラピューティクス， インコーポレイテッド Methods and compositions for treating liver damage
US20230050043A1 (en) 2019-12-23 2023-02-16 Pendulum Therapeutics, Inc. Compositions Comprising Microbes and Methods of Use and Making Thereof

Also Published As

Publication number Publication date
WO2016070151A1 (en) 2016-05-06
US20200345796A1 (en) 2020-11-05
US11364270B2 (en) 2022-06-21
US11278580B2 (en) 2022-03-22
US20210386798A1 (en) 2021-12-16
US9486487B2 (en) 2016-11-08
US11213556B2 (en) 2022-01-04
JP6868562B2 (en) 2021-05-19
US20190030095A1 (en) 2019-01-31
JP2017535597A (en) 2017-11-30
WO2016070151A9 (en) 2017-06-29
US10842830B2 (en) 2020-11-24
CA2964480A1 (en) 2016-05-06
CN113730442A (en) 2021-12-03
SG10201903823QA (en) 2019-05-30
CN108064132A (en) 2018-05-22
US20200261517A1 (en) 2020-08-20
US20200261518A1 (en) 2020-08-20
EP3212001A1 (en) 2017-09-06
US10668116B2 (en) 2020-06-02
US20190070228A1 (en) 2019-03-07
US20170027996A1 (en) 2017-02-02
US10675312B2 (en) 2020-06-09
US20190030096A1 (en) 2019-01-31
US20190070227A1 (en) 2019-03-07
US10842831B2 (en) 2020-11-24
GB2551642A (en) 2017-12-27
WO2016070151A8 (en) 2016-06-30
GB201707848D0 (en) 2017-06-28
US20160228476A1 (en) 2016-08-11
US20170020932A1 (en) 2017-01-26
EP3212001A4 (en) 2018-04-25
EP3881680A1 (en) 2021-09-22
GB2551642B (en) 2020-09-23
US11931387B2 (en) 2024-03-19

Similar Documents

Publication Publication Date Title
GB2551642B (en) Methods and compositions relating to microbial treatment and diagnosis of disorders
SG11201707657UA (en) Methods and compositions relating to microbial treatment and diagnosis of skin disorders
ZA201901279B (en) Compositions and methods for treatment of neurological disorders
EP3349783C0 (en) Compositions and methods relating to the treatment of diseases
IL251066B (en) Compositions and methods of use for treating metabolic disorders
ZA201700311B (en) Compositions and methods of use for treating metabolic disorders
HK1243325A1 (en) Compositions and methods to treat vision disorders
IL246942B (en) Micro-rnas and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone- associated medical conditions
HUE055913T2 (en) Methods and compositions for diagnosis and treatment of glioblastoma
EP3183005A4 (en) Methods and compositions for the treatment of metabolic disorders
EP3104776A4 (en) Diagnosis and treatment of respiratory disorders
EP3160493A4 (en) Compositions and methods to regulate renalase in the treatment of diseases and disorders
GB201404403D0 (en) Compositions and methods relating to the treatment of diseases
IL259710A (en) Compositions and methods of treatment for mvid and related diseases
IL251736B (en) Methods and compositions for the treatment of radiation-related disorders
HK1225994A1 (en) Compositions for use in the treatment of allergic conditions
EP3341079A4 (en) Methods and compositions relating to the diagnosis and treatment of cancer
EP3137908A4 (en) Methods and compositions for diagnosis and treatment of meningitis
PL3079684T3 (en) Compositions and methods for the treatment of diseases related to the renin-angiotensin-system
GB201411616D0 (en) Diagnosis and treatment of neurodegenerative disorders
GB201516303D0 (en) Compositions and methods relating to the treatment of diseases
GB201516437D0 (en) Compositions and methods relating to the treatment of disease
GB201418096D0 (en) Novel polymorph for use in treatment of inflammatory skin and pruritic disorders
GB201418272D0 (en) Composition & methods of treatment
GB201418268D0 (en) Composition & methods of treatment