SG11201610246PA - Residence structures and related methods - Google Patents

Residence structures and related methods

Info

Publication number
SG11201610246PA
SG11201610246PA SG11201610246PA SG11201610246PA SG11201610246PA SG 11201610246P A SG11201610246P A SG 11201610246PA SG 11201610246P A SG11201610246P A SG 11201610246PA SG 11201610246P A SG11201610246P A SG 11201610246PA SG 11201610246P A SG11201610246P A SG 11201610246PA
Authority
SG
Singapore
Prior art keywords
related methods
residence structures
residence
structures
methods
Prior art date
Application number
SG11201610246PA
Inventor
Andrew Bellinger
Shiyi Zhang
Carlo Giovanni Traverso
Robert S Langer
Stacy Mo
Tyler Grant
Mousa Jafari
Dean Liang Glettig
Angela Diciccio
Lowell L Wood Jr
Philip A Eckhoff
Original Assignee
Massachusetts Inst Technology
Brigham & Womens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201462010992P priority Critical
Application filed by Massachusetts Inst Technology, Brigham & Womens Hospital filed Critical Massachusetts Inst Technology
Priority to PCT/US2015/035423 priority patent/WO2015191920A1/en
Publication of SG11201610246PA publication Critical patent/SG11201610246PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6901Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/42Polycondensates having carboxylic or carbonic ester groups in the main chain
    • C08G18/4266Polycondensates having carboxylic or carbonic ester groups in the main chain prepared from hydroxycarboxylic acids and/or lactones
    • C08G18/4269Lactones
    • C08G18/4277Caprolactone and/or substituted caprolactone
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72Polyisocyanates or polyisothiocyanates
    • C08G18/73Polyisocyanates or polyisothiocyanates acyclic
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08Lactones or lactides
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002Dendritic macromolecules
    • C08G83/005Hyperbranched macromolecules
    • C08G83/006After treatment of hyperbranched macromolecules
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/02Homopolymers or copolymers of acids; Metal or ammonium salts thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/04Homopolymers or copolymers of esters
    • C08L33/06Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, which oxygen atoms are present only as part of the carboxyl radical
    • C08L33/08Homopolymers or copolymers of acrylic acid esters
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/04Homopolymers or copolymers of esters
    • C08L33/14Homopolymers or copolymers of esters of esters containing halogen, nitrogen, sulfur, or oxygen atoms in addition to the carboxy oxygen
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2230/00Compositions for preparing biodegradable polymers
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00Applications
    • C08L2203/02Applications for biomedical use
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y02A50/38Medical treatment of vector-borne diseases characterised by the agent
    • Y02A50/408Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a protozoa
    • Y02A50/411Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a protozoa of the genus Plasmodium, i.e. Malaria
SG11201610246PA 2014-06-11 2015-06-11 Residence structures and related methods SG11201610246PA (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US201462010992P true 2014-06-11 2014-06-11
PCT/US2015/035423 WO2015191920A1 (en) 2014-06-11 2015-06-11 Residence structures and related methods

Publications (1)

Publication Number Publication Date
SG11201610246PA true SG11201610246PA (en) 2017-01-27

Family

ID=54834353

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201610246PA SG11201610246PA (en) 2014-06-11 2015-06-11 Residence structures and related methods

Country Status (12)

Country Link
US (5) US20170135954A1 (en)
EP (3) EP3154553A4 (en)
JP (3) JP2017519003A (en)
KR (1) KR20170016960A (en)
CN (3) CN106573999A (en)
AU (4) AU2015274453A1 (en)
BR (1) BR112016028957A2 (en)
CA (3) CA2951909A1 (en)
MX (1) MX2016016406A (en)
RU (1) RU2017100273A3 (en)
SG (1) SG11201610246PA (en)
WO (3) WO2015191922A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103948557A (en) 2014-04-08 2014-07-30 闻晓光 Novel controlled release tablet
JP6570043B2 (en) 2014-06-02 2019-09-04 クレシオ・バイオサイエンシズ・リミテッド Inflatable gastroretentive dosage form
RU2017100273A3 (en) 2014-06-11 2018-11-12
US20180311154A1 (en) * 2015-10-23 2018-11-01 Lyndra, Inc. Gastric residence systems for sustained release of therapeutic agents and methods of use thereof
US10470799B2 (en) * 2016-04-21 2019-11-12 Massachusetts Institute Of Technology Origami robots, systems, and methods of treatment
AU2017268840A1 (en) * 2016-05-27 2018-11-22 Lyndra, Inc. Materials architecture for gastric residence systems
WO2018064630A1 (en) * 2016-09-30 2018-04-05 Lyndra, Inc. Gastric residence systems for sustained delivery of adamantane-class drugs
EP3320898A1 (en) 2016-11-11 2018-05-16 ratiopharm GmbH Dosage form comprising a carrier structure and method for manufacturing the dosage form
JP2019536800A (en) * 2016-12-02 2019-12-19 クレキシオ バイオサイエンシーズ エルティーディー. Gastric retention system
AU2018269704A1 (en) * 2017-05-17 2019-11-28 Massachusetts Institute Of Technology Self-righting systems, methods, and related components
AU2018279853A1 (en) * 2017-06-09 2020-01-02 Lyndra, Inc. Gastric residence systems with release rate-modulating films
WO2019083483A2 (en) * 2017-10-11 2019-05-02 Ege Universitesi A vaginal implant
CN107773554A (en) * 2017-09-07 2018-03-09 华南农业大学 A kind of ivermectin slow-releasing microcapsule and its preparation method and application
WO2019060458A1 (en) * 2017-09-20 2019-03-28 Lyndra, Inc. Encapsulation of gastric residence systems

Family Cites Families (111)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US202159A (en) * 1878-04-09 Improvement in axes
US415671A (en) * 1889-11-19 harris
US3154461A (en) * 1960-03-07 1964-10-27 Minnesota Mining & Mfg Matte-finish polymeric film and method of forming the same
AU449029B2 (en) 1969-08-28 1974-04-17 Commonwealth Scientific And Industrial Research Organisation Device for administration to ruminants
JPS5512411B2 (en) 1974-03-12 1980-04-02
US4451260A (en) 1982-03-26 1984-05-29 Minnesota Mining And Manufacturing Company Sustained release oral medicinal delivery device
US4676507A (en) 1985-05-06 1987-06-30 Patterson Bruce D Puzzles forming platonic solids
EP0202159B1 (en) * 1985-05-10 1991-07-03 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
US4735804A (en) 1985-05-10 1988-04-05 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
JPS6226215A (en) * 1985-05-10 1987-02-04 Merck & Co Inc Drug transmission device keeping in stomach during controlled time
US4758436A (en) 1985-05-29 1988-07-19 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
US4767627A (en) 1985-05-29 1988-08-30 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
IL87710A (en) 1987-09-18 1992-06-21 Ciba Geigy Ag Covered floating retard form for controlled release in gastric juice
US5002772A (en) 1988-05-31 1991-03-26 Pfizer Inc. Gastric retention system for controlled drug release
NZ228382A (en) * 1989-03-17 1992-08-26 Carter Holt Harvey Plastic Pro Drug administering coil-like device for insertion in body cavity of animal
US5007790A (en) 1989-04-11 1991-04-16 Depomed Systems, Inc. Sustained-release oral drug dosage form
JPH03163011A (en) 1989-08-31 1991-07-15 Yamanouchi Pharmaceut Co Ltd Device stayed in stomach
US5047464A (en) * 1989-09-20 1991-09-10 Merck & Co., Inc. Bioerodible thermoset elastomers
US5369142A (en) * 1993-01-15 1994-11-29 The Ohio State University Water soluble polymers containing amino acid residues for dental restoratives
WO1995003558A1 (en) * 1993-07-19 1995-02-02 Reflexite Corporation Retroreflective structure
DE4406424A1 (en) 1994-02-28 1995-08-31 Bayer Ag Expandable dosage forms
US6962579B2 (en) 1995-03-23 2005-11-08 Advanced Animal Technology Limited Substance delivery device
DE69625831T2 (en) 1995-03-23 2003-11-20 Advanced Animal Technology Ltd Device for administering a substance
US5840332A (en) 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system
AU2521797A (en) * 1996-04-12 1997-11-07 Japan Atomic Energy Research Institute Ph-sensitive polymers
JP2001527023A (en) 1997-08-11 2001-12-25 アルザ・コーポレーション Extended release active agent dosage form adapted for retention in the stomach
DE19850309A1 (en) 1998-10-30 2000-05-04 Lohmann Therapie Syst Lts Expandable gastroretensives therapy system with prolonged gastric residence
IL133196D0 (en) 1999-11-29 2001-03-19 Yissum Res Dev Co Gastroretentive controlled release pharmaceutical dosage forms
WO2001091553A1 (en) 2000-05-26 2001-12-06 Demegen, Inc. Composite wafer for controlled drug delivery
US6488962B1 (en) 2000-06-20 2002-12-03 Depomed, Inc. Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms
US8158143B2 (en) 2000-07-14 2012-04-17 Helmholtz-Zentrum Geesthacht Zentrum Fuer Material- Und Kuestenforschung Gmbh Systems for releasing active ingredients, based on biodegradable or biocompatible polymers with a shape memory effect
US7803392B2 (en) 2000-12-27 2010-09-28 University Of Kentucky Research Foundation pH-Sensitive mucoadhesive film-forming gels and wax-film composites suitable for topical and mucosal delivery of molecules
US6627206B2 (en) * 2001-07-25 2003-09-30 Greg A. Lloyd Method and apparatus for treating obesity and for delivering time-released medicaments
US20040219186A1 (en) * 2001-08-16 2004-11-04 Ayres James W. Expandable gastric retention device
EP1416914A1 (en) 2001-08-16 2004-05-12 The State of Oregon acting by and through The State Board of Higher Education on behalf of Oregon State University Expandable gastric retention device
US20050165136A1 (en) * 2002-01-23 2005-07-28 Uab Research Foundation Glass-ionomer cements containing amino acids
AU2003234159A1 (en) * 2002-04-22 2003-11-03 Purdue Research Foundation Hydrogels having enhanced elasticity and mechanical strength properties
DE10224352A1 (en) 2002-06-01 2003-12-11 Mueller Schulte Detlef Thermosensitive polymer carrier with changeable physical structure for biochemical analysis, diagnostics and therapy
GB0214013D0 (en) 2002-06-18 2002-07-31 Euro Celtique Sa Pharmaceutical product
AR040672A1 (en) 2002-07-25 2005-04-13 Glaxo Group Ltd Multicomponenete pharmaceutical dosage form, suitable body for use in the same and process for preparing
AU2003282603A1 (en) 2002-10-11 2004-05-04 Depomed Development Ltd Gastro-retentive levodopa delivery form
WO2004073690A1 (en) 2003-02-19 2004-09-02 Mnemoscience Gmbh Self-expanding device for the gastrointestinal or urogenital area
JP4497833B2 (en) * 2003-04-21 2010-07-07 富士フイルム株式会社 Positive lithographic printing plate precursor
US7662864B2 (en) * 2003-06-04 2010-02-16 Rutgers, The State University Of New Jersey Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent
CA2527976C (en) 2003-06-13 2011-11-22 Mnemoscience Gmbh Stents
EP1638533A1 (en) 2003-06-18 2006-03-29 John Michael Newton Controlled release devices with lumens
US20090259236A2 (en) 2003-07-28 2009-10-15 Baronova, Inc. Gastric retaining devices and methods
US8048169B2 (en) * 2003-07-28 2011-11-01 Baronova, Inc. Pyloric valve obstructing devices and methods
US6825308B1 (en) * 2003-10-29 2004-11-30 Council Of Scientific And Industrial Research Copolymers and preparation thereof
US20050201974A1 (en) 2003-12-09 2005-09-15 Spherics, Inc. Bioadhesive polymers with catechol functionality
EP1773303A2 (en) * 2004-05-25 2007-04-18 Chimeracore, Inc. Self-assembling nanoparticle drug delivery system
DE102004047076A1 (en) 2004-09-28 2006-04-06 Zimmer Ag Process for the preparation of polyesters
IL166183D0 (en) 2005-01-06 2006-01-15 Yissum Res Dev Co Novel diagnostic and imaging techniques of the gi tract
WO2006081497A2 (en) * 2005-01-27 2006-08-03 Corium International, Inc. Hydrophilic biocompatible adhesive formulations and uses
ES2540929T3 (en) 2005-02-01 2015-07-14 Emisphere Technologies, Inc. Gastric retention and controlled release administration system
US7785291B2 (en) 2005-03-01 2010-08-31 Tulip Medical Ltd. Bioerodible self-deployable intragastric implants
JP2006323082A (en) * 2005-05-18 2006-11-30 Canon Inc Developer supply container
US8021384B2 (en) 2005-07-26 2011-09-20 Ram Weiss Extending intrabody capsule
EP1911518A1 (en) 2005-08-05 2008-04-16 Shiga Prefecture Material for transfer of substance in liquid comprising polymer blend
WO2007048223A2 (en) 2005-10-25 2007-05-03 Pharmascience Inc. A gastric retention drug delivery system
US8187633B2 (en) * 2005-11-03 2012-05-29 Sun Pharma Advanced Research Company Limited Controlled release coated tablets having prolonged gastric retention
US7674396B2 (en) 2005-11-08 2010-03-09 Plensat Llc Method and system for treatment of eating disorders
PL1981465T3 (en) 2006-01-18 2016-03-31 Intec Pharma Ltd Method for forming delivery devices for oral intake of an agent
CA2642479C (en) 2006-02-15 2014-08-19 Intec Pharma Ltd. A gastro-retentive system for the delivery of macromolecules
US7691151B2 (en) 2006-03-31 2010-04-06 Spiration, Inc. Articulable Anchor
EP1886665A1 (en) 2006-08-01 2008-02-13 Boehringer Ingelheim Pharma GmbH & Co. KG Gastro retentive delivery system
EP2068844A4 (en) 2006-09-04 2013-01-23 Panacea Biotec Ltd Programmable buoyant delivery technology
US20080075766A1 (en) 2006-09-25 2008-03-27 Shun-Por Li Multi-core dosage form having transparent outer coating
US20080089933A1 (en) 2006-10-16 2008-04-17 Amir Alon Device and method for reducing calorie intake
EP2063867A2 (en) 2006-12-22 2009-06-03 Combinatorx, Incorporated Pharmaceutical compositions for treatment of parkinson's disease and related disorders
US8507778B2 (en) 2007-03-13 2013-08-13 Arthur J. Olson Self-assembled polyhedra
WO2008148083A1 (en) * 2007-05-25 2008-12-04 Gorham Enterprises Llc Bariatric magnetic apparatus and method of manufacturing thereof
WO2010020098A1 (en) 2008-08-18 2010-02-25 北京天衡药物研究院 Gastric retention drug delivery system, preparation method and use thereof
US8038659B2 (en) * 2007-10-17 2011-10-18 The Invention Science Fund I, Llc Disintegrating digestive tract interaction system
JP5607550B2 (en) 2008-03-11 2014-10-15 ディポメド,インコーポレイティド Gastric retentive sustained release dosage form comprising a combination of a non-opioid analgesic and an opioid analgesic
US20130273135A1 (en) 2008-03-25 2013-10-17 University Of Utah Research Foundation Controlled Release Combination Biomaterials
WO2009144558A1 (en) 2008-04-18 2009-12-03 Intec Pharma Ltd. Carbidopa/lipodopa gastroretentive drug delivery
WO2009132461A1 (en) * 2008-04-28 2009-11-05 Electronic Dietary Foods Inc. Bezoar-forming units for weight control
US20100256342A1 (en) * 2008-08-12 2010-10-07 Francis Raymond Salemme Protein nodes for controlled nanoscale assembly
WO2010035273A2 (en) 2008-09-29 2010-04-01 Intec Pharma Ltd. Novel gastroretentive delivery system
PL2378883T3 (en) 2008-12-04 2016-06-30 Intec Pharma Ltd Zaleplon gastroretentive drug delivery system
WO2010074712A2 (en) * 2008-12-27 2010-07-01 Duggirala Chandra S Devices for treating obesity and methods of using those devices
CN102414116B (en) * 2009-02-26 2015-01-21 加利福尼亚大学董事会 A supramolecular approach for preparation of size controllable nanoparticles
US8414559B2 (en) 2009-05-07 2013-04-09 Rainbow Medical Ltd. Gastroretentive duodenal pill
DE102009028076A1 (en) * 2009-07-29 2011-02-03 Evonik Röhm Gmbh Coating composition for dip coating of capsule halves
US20110052700A1 (en) 2009-08-31 2011-03-03 Depomed, Inc. Gastric retentive pharmaceutical compositions for immediate and extended release of levosulpiride
WO2011032087A2 (en) 2009-09-11 2011-03-17 Replication Medical Inc. Swellable polymeric device for dietary regulation
WO2011048494A2 (en) 2009-10-19 2011-04-28 Intec Pharma Ltd. Novel gastroretentive dosage forms of poorly soluble drugs
US9421169B2 (en) 2009-11-20 2016-08-23 Covidien Lp Oral dosage forms for delivery of therapeutic agents
CN101711752B (en) 2009-11-26 2011-09-21 中国科学院上海药物研究所 Controlled release preparation of benzo-isoxazole derivant and preparation method thereof
WO2011139796A2 (en) * 2010-04-27 2011-11-10 The Johns Hopkins University Self-folding sub-centimeter structures
US20120165792A1 (en) 2010-12-22 2012-06-28 Ethicon Endo-Surgery, Inc. Pill Catchers
US20120165794A1 (en) 2010-12-22 2012-06-28 Ethicon Endo-Surgery, Inc. Pill Catchers
US20120165793A1 (en) 2010-12-22 2012-06-28 Ethicon Endo-Surgery, Inc. Pill Catchers
RU2598057C2 (en) 2011-02-04 2016-09-20 ТАРИС Биомедикал ЛЛК Implantable device for controlled release of drug with low solubility
AU2013290875A1 (en) 2012-07-16 2015-02-05 APET Holding B.V. Gastro-retentive drug delivery system
US9228859B2 (en) * 2011-09-26 2016-01-05 Northeastern University Customizable embedded sensors
US8979887B2 (en) 2012-02-24 2015-03-17 Elwha Llc Devices, systems, and methods to control stomach volume
US9307966B2 (en) 2012-08-15 2016-04-12 St. Jude Medical Puerto Rico Llc Vascular closure device anchor
WO2014028878A1 (en) 2012-08-16 2014-02-20 Teva Pharmaceutical Industries Ltd. Pharmaceutical compositions of memantine
US10441760B2 (en) 2013-03-01 2019-10-15 The Johns Hopkins University Self-actuating chemomechanical devices for delivery and extended release of therapeutic agents in the gastrointestinal tract
CA2932574A1 (en) 2013-12-05 2015-06-11 Tulip Medical Ltd. Retentive devices and systems for in-situ release of pharmaceutical active agents
WO2015168297A1 (en) 2014-04-29 2015-11-05 Massachusetts Institute Of Technology Polymeric materials for bio-applications
EA201692388A1 (en) 2014-05-26 2017-05-31 Грюненталь Гмбх Dosage form as particle multiple, protected against called dose reset by ethanol
RU2017100273A3 (en) 2014-06-11 2018-11-12
US20170266112A1 (en) * 2014-06-11 2017-09-21 Massachusetts Institute Of Technology Residence structures and related methods
JP2018515476A (en) 2015-05-01 2018-06-14 マサチューセッツ インスティテュート オブ テクノロジー Inducible shape memory guidance device
US20180311154A1 (en) 2015-10-23 2018-11-01 Lyndra, Inc. Gastric residence systems for sustained release of therapeutic agents and methods of use thereof
BR112018011636A2 (en) 2015-12-08 2018-11-27 Lyndra Inc geometric configurations for gastric residence systems
AU2017268840A1 (en) 2016-05-27 2018-11-22 Lyndra, Inc. Materials architecture for gastric residence systems
WO2018064630A1 (en) 2016-09-30 2018-04-05 Lyndra, Inc. Gastric residence systems for sustained delivery of adamantane-class drugs

Also Published As

Publication number Publication date
AU2015274453A2 (en) 2017-01-19
US10413507B2 (en) 2019-09-17
AU2015274451B2 (en) 2019-06-20
US20170106099A1 (en) 2017-04-20
WO2015191925A8 (en) 2016-02-11
WO2015191925A1 (en) 2015-12-17
WO2015191920A1 (en) 2015-12-17
AU2015274451A1 (en) 2017-01-12
WO2015191920A8 (en) 2016-02-04
US20190070107A1 (en) 2019-03-07
US10182985B2 (en) 2019-01-22
RU2017100273A (en) 2018-07-11
EP3155024A4 (en) 2018-01-17
CN106573015A (en) 2017-04-19
CN106573999A (en) 2017-04-19
EP3154622A1 (en) 2017-04-19
KR20170016960A (en) 2017-02-14
US20170128576A1 (en) 2017-05-11
EP3154622A4 (en) 2018-01-17
EP3154553A1 (en) 2017-04-19
JP2017524662A (en) 2017-08-31
US20190133936A1 (en) 2019-05-09
AU2015274451C1 (en) 2019-09-12
JP2017519098A (en) 2017-07-13
JP2017519003A (en) 2017-07-13
AU2019232862A1 (en) 2019-10-10
CN106714893A (en) 2017-05-24
CA2951902A1 (en) 2015-12-17
US20190175500A1 (en) 2019-06-13
US20170135954A1 (en) 2017-05-18
CA2951909A1 (en) 2015-12-17
AU2015274453A1 (en) 2017-01-12
EP3155024A1 (en) 2017-04-19
EP3154553A4 (en) 2018-03-28
US20190298652A1 (en) 2019-10-03
WO2015191922A1 (en) 2015-12-17
BR112016028957A2 (en) 2017-08-22
RU2017100273A3 (en) 2018-11-12
US20190070108A1 (en) 2019-03-07
MX2016016406A (en) 2017-10-12
AU2015274456A1 (en) 2017-01-12
CA2951884A1 (en) 2015-12-17

Similar Documents

Publication Publication Date Title
HK1217861A1 (en) Wifi-coordinated laa-lte
ZA201700973B (en) Device and method
IL249188D0 (en) Anti-her2 glycoantibodies and uses thereof
SG11201609892RA (en) Transport-container system and method
JP2014081953A5 (en) System and equipment
EP3154622A4 (en) Self-assembled residence devices and related methods
BR112016016289A2 (en) heteroari and uses thereof
SG11201703767XA (en) Anti-interleukin-33 antibodies and uses thereof
GB201419094D0 (en) Anti-TIM-3-antibodies
GB201404893D0 (en) Selfie - Stick
SG11201703880VA (en) Triazolopyrimidine compounds and uses thereof
GB201506913D0 (en) Inductor structure and application thereof
AU359704S (en) Case
PT3126388T (en) Anti-egfrviii antibodies and uses thereof
SG10201405182WA (en) Method and system
GB2541823B (en) Security elements and methods of their manufacture
AU361515S (en) Dishrack
RU2016135637A (en) 6-heteroaryloxy- and 6-ariloxychinolin-2-carboxamides and their application
RU2017111265A (en) Difluoromethylaminopyridines and Difluoromethylaminopyrimidines
GB2528557B (en) Soundbar
IL251097D0 (en) Neural microphysiological systems and methods of using the same
GB201407711D0 (en) Communnication system and related method
SG10201500986TA (en) Catheter devices and related methods
GB201507294D0 (en) Early Entry
GB2529896B (en) Multirotor