SG11201609948YA - Lobaplatin crystal, preparation method and pharmaceutical application - Google Patents

Lobaplatin crystal, preparation method and pharmaceutical application

Info

Publication number
SG11201609948YA
SG11201609948YA SG11201609948YA SG11201609948YA SG11201609948YA SG 11201609948Y A SG11201609948Y A SG 11201609948YA SG 11201609948Y A SG11201609948Y A SG 11201609948YA SG 11201609948Y A SG11201609948Y A SG 11201609948YA SG 11201609948Y A SG11201609948Y A SG 11201609948YA
Authority
SG
Singapore
Prior art keywords
preparation
pharmaceutical application
lobaplatin crystal
lobaplatin
crystal
Prior art date
Application number
SG11201609948YA
Other languages
English (en)
Inventor
Qiling Dou
Donghu Sui
Shenggui Zhang
Original Assignee
Guizhou Yibai Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN201410279879.8A external-priority patent/CN105440083B/zh
Priority claimed from CN201410279331.3A external-priority patent/CN105440082B/zh
Priority claimed from CN201410279369.0A external-priority patent/CN105198932B/zh
Application filed by Guizhou Yibai Pharmaceutical filed Critical Guizhou Yibai Pharmaceutical
Publication of SG11201609948YA publication Critical patent/SG11201609948YA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0013—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
SG11201609948YA 2014-06-20 2014-11-28 Lobaplatin crystal, preparation method and pharmaceutical application SG11201609948YA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN201410279879.8A CN105440083B (zh) 2014-06-20 2014-06-20 一种洛铂晶体、制备方法及药物应用
CN201410279331.3A CN105440082B (zh) 2014-06-20 2014-06-20 一种洛铂晶体、制备方法及药物应用
CN201410279369.0A CN105198932B (zh) 2014-06-20 2014-06-20 洛铂二水合物、制备方法及药物应用
PCT/CN2014/092571 WO2015192606A1 (zh) 2014-06-20 2014-11-28 洛铂晶体、制备方法及药物应用

Publications (1)

Publication Number Publication Date
SG11201609948YA true SG11201609948YA (en) 2017-01-27

Family

ID=54934818

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201609948YA SG11201609948YA (en) 2014-06-20 2014-11-28 Lobaplatin crystal, preparation method and pharmaceutical application

Country Status (8)

Country Link
US (1) US9889112B2 (ja)
EP (1) EP3159349B1 (ja)
JP (1) JP6404461B2 (ja)
KR (1) KR20170018822A (ja)
PH (1) PH12016502359A1 (ja)
RU (1) RU2648990C1 (ja)
SG (1) SG11201609948YA (ja)
WO (1) WO2015192606A1 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7180923B2 (ja) 2018-09-01 2022-11-30 ベイジン ショウバイ ファーマシューティカル カンパニー，リミティッド 白金系化合物リン酸塩及びその製造方法
CN111721840B (zh) * 2019-03-19 2022-07-12 海南长安国际制药有限公司 洛铂中有关物质的检测
CN111721841B (zh) * 2019-03-19 2022-07-12 海南长安国际制药有限公司 与洛铂有关物质的检测
CN113173953B (zh) * 2021-04-12 2022-06-10 昆明贵研药业有限公司 用于制备抗肿瘤药物的高纯洛铂三水合物的提纯方法
CN115032297B (zh) * 2022-05-27 2023-11-14 四川汇宇制药股份有限公司 反式-1,2-二氨甲基环丁烷与其顺式异构体的分离检测方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE86967T1 (de) * 1988-01-09 1993-04-15 Asta Medica Ag 1,2-bis(aminomethyl)cyclobutan-platin-komplexe.
DE4415263C1 (de) * 1994-04-15 1995-11-30 Asta Medica Ag Cis-[trans-1,2-Cyclobutanbis(methylamin)-N,N']-[(2S)-lactato-O·1·, O·2·]-platin(II)-trihydrat (Lobaplatin-Trihydrat), seine Herstellung und arzneiliche Verwendung
CN102020679B (zh) * 2010-11-24 2013-12-25 贵州益佰制药股份有限公司 一种以草酸盐制备洛铂三水合物的方法

Also Published As

Publication number Publication date
PH12016502359B1 (en) 2017-02-13
US20170189367A1 (en) 2017-07-06
EP3159349B1 (en) 2020-08-05
JP6404461B2 (ja) 2018-10-10
EP3159349A4 (en) 2017-10-25
WO2015192606A1 (zh) 2015-12-23
KR20170018822A (ko) 2017-02-20
PH12016502359A1 (en) 2017-02-13
EP3159349A1 (en) 2017-04-26
JP2017517572A (ja) 2017-06-29
US9889112B2 (en) 2018-02-13
RU2648990C1 (ru) 2018-03-29

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