SG11201510617WA - Methods and compositions for dengue virus vaccines - Google Patents
Methods and compositions for dengue virus vaccinesInfo
- Publication number
- SG11201510617WA SG11201510617WA SG11201510617WA SG11201510617WA SG11201510617WA SG 11201510617W A SG11201510617W A SG 11201510617WA SG 11201510617W A SG11201510617W A SG 11201510617WA SG 11201510617W A SG11201510617W A SG 11201510617WA SG 11201510617W A SG11201510617W A SG 11201510617WA
- Authority
- SG
- Singapore
- Prior art keywords
- compositions
- methods
- dengue virus
- virus vaccines
- vaccines
- Prior art date
Links
- 229940023605 dengue virus vaccine Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/18—Togaviridae; Flaviviridae
- C07K14/1816—Flaviviridae, e.g. pestivirus, mucosal disease virus, bovine viral diarrhoea virus, classical swine fever virus (hog cholera virus), border disease virus
- C07K14/1825—Flaviviruses or Group B arboviruses, e.g. yellow fever virus, japanese encephalitis, tick-borne encephalitis, dengue
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361839687P | 2013-06-26 | 2013-06-26 | |
| PCT/US2014/044410 WO2014210358A1 (en) | 2013-06-26 | 2014-06-26 | Methods and compositions for dengue virus vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201510617WA true SG11201510617WA (en) | 2016-01-28 |
Family
ID=52142690
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201510617WA SG11201510617WA (en) | 2013-06-26 | 2014-06-26 | Methods and compositions for dengue virus vaccines |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10053493B2 (ja) |
| EP (2) | EP3590955A1 (ja) |
| JP (2) | JP6525984B2 (ja) |
| KR (1) | KR20160027019A (ja) |
| CN (2) | CN105473603B (ja) |
| AU (2) | AU2014302282B2 (ja) |
| BR (1) | BR112015032388A8 (ja) |
| CA (1) | CA2918644A1 (ja) |
| ES (1) | ES2745431T3 (ja) |
| MX (2) | MX365957B (ja) |
| SG (1) | SG11201510617WA (ja) |
| WO (1) | WO2014210358A1 (ja) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015338859A1 (en) | 2014-11-02 | 2017-06-01 | The University Of North Carolina At Chapel Hill | Methods and compositions for recombinant dengue viruses for vaccine and diagnostic development |
| TWI769185B (zh) * | 2016-10-27 | 2022-07-01 | 海樂源有限公司 | 登革熱類病毒顆粒、抗登革熱病毒抗體、及含其之組合物 |
| WO2018217906A1 (en) * | 2017-05-23 | 2018-11-29 | The University Of North Carolina At Chapel Hill | Methods and compositions for dengue virus serotype 4 epitopes |
| WO2018231974A1 (en) * | 2017-06-14 | 2018-12-20 | Thomas Jefferson University | Composition and administration of chimeric glycoprotein lyssavirus vaccines for coverage against rabies |
| WO2023056335A1 (en) * | 2021-09-30 | 2023-04-06 | The University Of North Carolina At Chapel Hill | Methods and compositions for recombinant dengue viruses for vaccine and diagnostic development |
| CN116716322B (zh) * | 2023-05-12 | 2024-05-31 | 中山大学 | 一种denv-3全长感染性克隆及其构建方法与应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4501729A (en) | 1982-12-13 | 1985-02-26 | Research Corporation | Aerosolized amiloride treatment of retained pulmonary secretions |
| CA1247080A (en) | 1983-03-08 | 1988-12-20 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
| PL170980B1 (pl) | 1992-06-25 | 1997-02-28 | Smithkline Beecham Biolog | Szczepionka PL PL PL PL PL PL PL |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| CU22683A1 (es) * | 1997-01-15 | 2001-07-20 | Inst De Medicina Tropical Pedro Kouri | Epítopes de la proteína pre-m/m del virus del dengue, péptidos sintéticos, proteínas quiméricas y sus usos |
| US6432411B1 (en) | 1999-07-13 | 2002-08-13 | Hawaii Biotechnology Group | Recombinant envelope vaccine against flavivirus infection |
| CA2572921C (en) | 2004-07-09 | 2017-01-03 | The University Of North Carolina At Chapel Hill | Replication-competent and propagation-defective venezuelan equine encephalitis (vee) viral adjuvants |
| US7906292B2 (en) * | 2004-07-27 | 2011-03-15 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Localization and characterization of flavivirus envelope glycoprotein cross-reactive epitopes and methods for their use |
| EA015907B1 (ru) | 2004-10-20 | 2011-12-30 | Санофи Пастер Байолоджикс Ко. | Рекомбинантный флавивирус и его применение |
| CU23586A1 (es) * | 2005-11-22 | 2010-10-30 | Ct Ingenieria Genetica Biotech | Métodos y proteínas para el tratamiento profiláctico y/o terapéutico de los cuatro serotipos del virus de dengue y otros flavivirus |
| WO2011119716A2 (en) | 2010-03-24 | 2011-09-29 | Research Development Foundation | Flavivirus host range mutations and uses thereof |
| WO2011146933A2 (en) * | 2010-05-21 | 2011-11-24 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Universal dengue virus sequences and methods of use |
| WO2012027473A2 (en) | 2010-08-24 | 2012-03-01 | The University Of North Carolina At Chapel Hill | Immunogenic compositions comprising alphavirus vectored dengue virus e protein antigens |
| US9376486B2 (en) * | 2010-12-14 | 2016-06-28 | National University Of Singapore | Human monoclonal antibody with specificity for Dengue virus serotype 1 E protein and uses thereof |
| AU2012326079B2 (en) | 2011-10-20 | 2017-01-12 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Dengue virus E-glycoprotein polypeptides containing mutations that eliminate immunodominant cross-reactive epitopes |
| EP2834265A4 (en) * | 2012-04-02 | 2015-10-14 | Univ North Carolina | METHODS AND COMPOSITIONS FOR DENGUE VIRUS EPITOPES |
-
2014
- 2014-06-26 AU AU2014302282A patent/AU2014302282B2/en not_active Ceased
- 2014-06-26 EP EP19176621.1A patent/EP3590955A1/en not_active Withdrawn
- 2014-06-26 MX MX2016000235A patent/MX365957B/es active IP Right Grant
- 2014-06-26 SG SG11201510617WA patent/SG11201510617WA/en unknown
- 2014-06-26 US US14/392,127 patent/US10053493B2/en not_active Expired - Fee Related
- 2014-06-26 CN CN201480047442.XA patent/CN105473603B/zh not_active Expired - Fee Related
- 2014-06-26 EP EP14817079.8A patent/EP3013852B1/en not_active Not-in-force
- 2014-06-26 CN CN201910931774.9A patent/CN110734500A/zh active Pending
- 2014-06-26 WO PCT/US2014/044410 patent/WO2014210358A1/en active Application Filing
- 2014-06-26 BR BR112015032388A patent/BR112015032388A8/pt not_active IP Right Cessation
- 2014-06-26 ES ES14817079T patent/ES2745431T3/es active Active
- 2014-06-26 JP JP2016524209A patent/JP6525984B2/ja not_active Expired - Fee Related
- 2014-06-26 KR KR1020167001891A patent/KR20160027019A/ko not_active Application Discontinuation
- 2014-06-26 CA CA2918644A patent/CA2918644A1/en not_active Abandoned
-
2016
- 2016-01-07 MX MX2019007252A patent/MX2019007252A/es unknown
-
2018
- 2018-08-20 US US16/105,346 patent/US10870682B2/en active Active
- 2018-12-12 AU AU2018278927A patent/AU2018278927A1/en not_active Abandoned
-
2019
- 2019-05-07 JP JP2019087452A patent/JP2019195328A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014210358A1 (en) | 2014-12-31 |
| CA2918644A1 (en) | 2014-12-31 |
| US10053493B2 (en) | 2018-08-21 |
| MX2016000235A (es) | 2016-08-11 |
| US20160257719A1 (en) | 2016-09-08 |
| CN105473603A (zh) | 2016-04-06 |
| EP3590955A1 (en) | 2020-01-08 |
| JP2019195328A (ja) | 2019-11-14 |
| US20190225654A1 (en) | 2019-07-25 |
| MX2019007252A (es) | 2019-08-16 |
| EP3013852A4 (en) | 2017-02-15 |
| AU2014302282B2 (en) | 2018-09-13 |
| AU2014302282A1 (en) | 2016-02-11 |
| AU2018278927A1 (en) | 2019-01-17 |
| US10870682B2 (en) | 2020-12-22 |
| KR20160027019A (ko) | 2016-03-09 |
| EP3013852B1 (en) | 2019-06-19 |
| ES2745431T3 (es) | 2020-03-02 |
| JP2016523912A (ja) | 2016-08-12 |
| BR112015032388A2 (pt) | 2017-07-25 |
| BR112015032388A8 (pt) | 2020-01-14 |
| EP3013852A1 (en) | 2016-05-04 |
| MX365957B (es) | 2019-06-20 |
| CN110734500A (zh) | 2020-01-31 |
| CN105473603B (zh) | 2019-10-25 |
| JP6525984B2 (ja) | 2019-06-05 |
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