SG11201408337PA - Methods of decellularizing bone - Google Patents

Methods of decellularizing bone

Info

Publication number
SG11201408337PA
SG11201408337PA SG11201408337PA SG11201408337PA SG11201408337PA SG 11201408337P A SG11201408337P A SG 11201408337PA SG 11201408337P A SG11201408337P A SG 11201408337PA SG 11201408337P A SG11201408337P A SG 11201408337PA SG 11201408337P A SG11201408337P A SG 11201408337PA
Authority
SG
Singapore
Prior art keywords
international
bone
methods
decellularizing
nesota
Prior art date
Application number
SG11201408337PA
Inventor
Jeffrey Ross
Blaise Porter
Original Assignee
Miromatrix Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201261659046P priority Critical
Application filed by Miromatrix Medical Inc filed Critical Miromatrix Medical Inc
Priority to PCT/US2013/045387 priority patent/WO2013188525A1/en
Publication of SG11201408337PA publication Critical patent/SG11201408337PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4644Preparation of bone graft, bone plugs or bone dowels, e.g. grinding or milling bone material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4644Preparation of bone graft, bone plugs or bone dowels, e.g. grinding or milling bone material
    • A61F2002/4646Devices for cleaning bone graft

Abstract

(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 19 December 2013 (19.12.2013) WIPOIPCT (10) International Publication Number WO 2013/188525 A1 (51) International Patent Classification: C12N 5/071 (2010.01) A61F 2/28 (2006.01) C12N 5/00 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/US2013/045387 12 June 2013 (12.06.2013) English (30) Priority Data: 61/659,046 13 June 2012 (13.06.2012) English US (72) Inventors; and (71) Applicants : ROSS, Jeffrey [US/US]; 470 Liberty Heights Drive, Chaska, Minnesota 55318 (US). PORTER, Blaise [US/US]; 18683 Bearpath Trail, Eden Prairie, Min­ nesota 55347 (US). (74) Agents: MADDEN, Robert et al.; Schwegman, Lundberg & Woessner, P.A., P.O. Box 2938, Minneapolis, Min­ nesota 55402 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) (54) Title: METHODS OF DECELLULARIZING BONE CJ oo 00 i-H en i-H o CJ O £ CANCELLOUS SPACE BEING FLUSHED OUT DRILL & TAP THIS AREA THREAD TO IN FITTING FLUID IN CAN ATTACH ANY TUBE TO APPLY FLUID/SOLVENT PRESSURE FLUID OUT ma 3 (57) Abstract: Methods of decellularizing bone, e.g., human bone, are provided.
SG11201408337PA 2012-06-13 2013-06-12 Methods of decellularizing bone SG11201408337PA (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US201261659046P true 2012-06-13 2012-06-13
PCT/US2013/045387 WO2013188525A1 (en) 2012-06-13 2013-06-12 Methods of decellularizing bone

Publications (1)

Publication Number Publication Date
SG11201408337PA true SG11201408337PA (en) 2015-01-29

Family

ID=48703894

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201408337PA SG11201408337PA (en) 2012-06-13 2013-06-12 Methods of decellularizing bone

Country Status (13)

Country Link
US (1) US9290738B2 (en)
EP (1) EP2861721A1 (en)
JP (2) JP2015524680A (en)
KR (1) KR20150033644A (en)
CN (1) CN104937094B (en)
AU (1) AU2013274322B2 (en)
BR (1) BR112014031224A2 (en)
CA (1) CA2876648C (en)
HK (1) HK1209159A1 (en)
IN (1) IN2014DN11201A (en)
MX (1) MX359769B (en)
SG (1) SG11201408337PA (en)
WO (1) WO2013188525A1 (en)

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KR20140040293A (en) 2005-08-26 2014-04-02 리전츠 오브 더 유니버스티 오브 미네소타 Decellularization and recellularization of organs and tissues
US9290738B2 (en) 2012-06-13 2016-03-22 Miromatrix Medical Inc. Methods of decellularizing bone
GB201310773D0 (en) * 2013-06-17 2013-07-31 Northwick Park Inst For Medcal Res Ltd Implant and method of producing an implant
JP6271298B2 (en) * 2014-02-28 2018-01-31 国立大学法人 東京医科歯科大学 Method for producing decellularized tissue
JP6302756B2 (en) * 2014-06-06 2018-03-28 シスメックス株式会社 Cell collection method and processed bone used in the method
EP3095469B1 (en) 2015-05-22 2019-09-11 Ilyas Inci Process for bone tissue decellularization
AU2016321301A1 (en) 2015-09-11 2018-03-29 The General Hospital Corporation Regeneration of a functional pulmonary vascular bed
CN107456603A (en) * 2016-06-03 2017-12-12 香港大学深圳医院 A kind of bone holder material and preparation method for being enriched with magnesium ion
CN106075583B (en) * 2016-07-07 2020-07-14 中国人民解放军第二军医大学 Method for preparing acellular matrix biological material by perfusion-pressure difference method
CN110227182B (en) * 2019-01-17 2020-12-15 浙江大学医学院附属邵逸夫医院 Preparation method of gradient mineralized bone extracellular matrix material
CN110237303B (en) * 2019-06-27 2021-06-29 浙江大学医学院附属邵逸夫医院 Preparation method of acellular periosteum matrix gel material from natural tissue source

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Also Published As

Publication number Publication date
CN104937094B (en) 2018-06-01
CA2876648C (en) 2020-09-22
MX2014015270A (en) 2015-08-12
US9290738B2 (en) 2016-03-22
EP2861721A1 (en) 2015-04-22
AU2013274322B2 (en) 2017-03-09
WO2013188525A1 (en) 2013-12-19
US20130337560A1 (en) 2013-12-19
MX359769B (en) 2018-10-10
CA2876648A1 (en) 2013-12-19
CN104937094A (en) 2015-09-23
JP2019072524A (en) 2019-05-16
KR20150033644A (en) 2015-04-01
JP2015524680A (en) 2015-08-27
AU2013274322A1 (en) 2015-01-29
HK1209159A1 (en) 2016-03-24
IN2014DN11201A (en) 2015-10-02
BR112014031224A2 (en) 2017-06-27

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