SG11201406538VA - Detection and quantitation of sample contamination in immune repertoire analysis - Google Patents
Detection and quantitation of sample contamination in immune repertoire analysisInfo
- Publication number
- SG11201406538VA SG11201406538VA SG11201406538VA SG11201406538VA SG11201406538VA SG 11201406538V A SG11201406538V A SG 11201406538VA SG 11201406538V A SG11201406538V A SG 11201406538VA SG 11201406538V A SG11201406538V A SG 11201406538VA SG 11201406538V A SG11201406538V A SG 11201406538VA
- Authority
- SG
- Singapore
- Prior art keywords
- quantitation
- detection
- immune repertoire
- sample contamination
- repertoire analysis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261624002P | 2012-04-13 | 2012-04-13 | |
| US201261658317P | 2012-06-11 | 2012-06-11 | |
| US201261738277P | 2012-12-17 | 2012-12-17 | |
| US201361768269P | 2013-02-22 | 2013-02-22 | |
| US13/834,794 US9528160B2 (en) | 2008-11-07 | 2013-03-15 | Rare clonotypes and uses thereof |
| US13/835,093 US9506119B2 (en) | 2008-11-07 | 2013-03-15 | Method of sequence determination using sequence tags |
| PCT/US2013/035857 WO2013155119A1 (en) | 2012-04-13 | 2013-04-09 | Detection and quantitation of sample contamination in immune repertoire analysis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201406538VA true SG11201406538VA (en) | 2014-11-27 |
Family
ID=49328112
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201406538VA SG11201406538VA (en) | 2012-04-13 | 2013-04-09 | Detection and quantitation of sample contamination in immune repertoire analysis |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP2836611A4 (en) |
| JP (1) | JP2015512655A (en) |
| CN (1) | CN104395481A (en) |
| AU (1) | AU2013246050B2 (en) |
| CA (1) | CA2869481A1 (en) |
| SG (1) | SG11201406538VA (en) |
| WO (1) | WO2013155119A1 (en) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
| US9394567B2 (en) | 2008-11-07 | 2016-07-19 | Adaptive Biotechnologies Corporation | Detection and quantification of sample contamination in immune repertoire analysis |
| SG195652A1 (en) | 2008-11-07 | 2013-12-30 | Sequenta Inc | Methods of monitoring conditions by sequence analysis |
| US8748103B2 (en) | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| US9506119B2 (en) | 2008-11-07 | 2016-11-29 | Adaptive Biotechnologies Corp. | Method of sequence determination using sequence tags |
| US8628927B2 (en) | 2008-11-07 | 2014-01-14 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| US9528160B2 (en) | 2008-11-07 | 2016-12-27 | Adaptive Biotechnolgies Corp. | Rare clonotypes and uses thereof |
| DK3059337T3 (en) | 2009-01-15 | 2019-07-22 | Adaptive Biotechnologies Corp | Adaptive immunity profiling and methods for producing monoclonal antibodies |
| JP2012531202A (en) | 2009-06-25 | 2012-12-10 | フレッド ハチンソン キャンサー リサーチ センター | How to measure adaptive immunity |
| US9043160B1 (en) | 2009-11-09 | 2015-05-26 | Sequenta, Inc. | Method of determining clonotypes and clonotype profiles |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| US10385475B2 (en) | 2011-09-12 | 2019-08-20 | Adaptive Biotechnologies Corp. | Random array sequencing of low-complexity libraries |
| CA2853088C (en) | 2011-10-21 | 2018-03-13 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| ES2867924T3 (en) | 2011-12-09 | 2021-10-21 | Adaptive Biotechnologies Corp | Diagnosis of Lymphoid Malignant Tumors and Detection of Minimal Residual Disease |
| US9499865B2 (en) | 2011-12-13 | 2016-11-22 | Adaptive Biotechnologies Corp. | Detection and measurement of tissue-infiltrating lymphocytes |
| EP2823060B1 (en) | 2012-03-05 | 2018-02-14 | Adaptive Biotechnologies Corporation | Determining paired immune receptor chains from frequency matched subunits |
| EP2831276B1 (en) | 2012-05-08 | 2016-04-20 | Adaptive Biotechnologies Corporation | Compositions and method for measuring and calibrating amplification bias in multiplexed pcr reactions |
| US20160002731A1 (en) | 2012-10-01 | 2016-01-07 | Adaptive Biotechnologies Corporation | Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization |
| US10150996B2 (en) | 2012-10-19 | 2018-12-11 | Adaptive Biotechnologies Corp. | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| US9868979B2 (en) | 2013-06-25 | 2018-01-16 | Prognosys Biosciences, Inc. | Spatially encoded biological assays using a microfluidic device |
| US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
| CA2941612A1 (en) | 2014-03-05 | 2015-09-11 | Adaptive Biotechnologies Corporation | Methods using randomer-containing synthetic molecules |
| US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
| US10392663B2 (en) | 2014-10-29 | 2019-08-27 | Adaptive Biotechnologies Corp. | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from a large number of samples |
| US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
| US11066705B2 (en) | 2014-11-25 | 2021-07-20 | Adaptive Biotechnologies Corporation | Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing |
| CA2976580A1 (en) | 2015-02-24 | 2016-09-01 | Adaptive Biotechnologies Corp. | Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing |
| US11041202B2 (en) | 2015-04-01 | 2021-06-22 | Adaptive Biotechnologies Corporation | Method of identifying human compatible T cell receptors specific for an antigenic target |
| CN107532207B (en) | 2015-04-10 | 2021-05-07 | 空间转录公司 | Spatially differentiated, multiplexed nucleic acid analysis of biological samples |
| CN105095687B (en) * | 2015-06-26 | 2018-10-26 | 南方科技大学 | A kind of immune group library data analysing method and terminal |
| AU2016315941B2 (en) | 2015-09-01 | 2022-09-08 | The Regents Of The University Of California | Modular polypeptide libraries and methods of making and using same |
| CA3004310A1 (en) * | 2015-11-04 | 2017-05-11 | Atreca, Inc. | Combinatorial sets of nucleic acid barcodes for analysis of nucleic acids associated with single cells |
| CN105740650B (en) * | 2016-03-02 | 2019-04-05 | 广西作物遗传改良生物技术重点开放实验室 | A method of quick and precisely identifying high-throughput genomic data pollution sources |
| US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
| WO2019046817A1 (en) | 2017-09-01 | 2019-03-07 | Life Technologies Corporation | Compositions and methods for immune repertoire sequencing |
| US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
| CN112189139A (en) * | 2018-09-26 | 2021-01-05 | 北卡罗来纳-查佩尔山大学 | Compounds, compositions and methods for improved assays |
| CN110970091B (en) * | 2019-12-20 | 2023-05-23 | 北京优迅医学检验实验室有限公司 | Label quality control method and device |
| CN111304309A (en) * | 2020-03-06 | 2020-06-19 | 上海韦翰斯生物医药科技有限公司 | Detection method for sequencing platform tag sequence pollution |
| CN116249785A (en) * | 2020-06-02 | 2023-06-09 | 10X基因组学有限公司 | Space transcriptomics for antigen-receptor |
| WO2021247543A2 (en) | 2020-06-02 | 2021-12-09 | 10X Genomics, Inc. | Nucleic acid library methods |
| WO2021252499A1 (en) | 2020-06-08 | 2021-12-16 | 10X Genomics, Inc. | Methods of determining a surgical margin and methods of use thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999020798A1 (en) * | 1997-10-23 | 1999-04-29 | Exact Laboratories, Inc. | Methods for detecting contamination in molecular diagnostics using pcr |
| EP1598429A1 (en) * | 2004-05-19 | 2005-11-23 | Amplion Ltd. | Detection of amplicon contamination during PCR exhibiting two different annealing temperatures |
| WO2007087312A2 (en) * | 2006-01-23 | 2007-08-02 | Population Genetics Technologies Ltd. | Molecular counting |
| ES2546848T3 (en) * | 2006-03-10 | 2015-09-29 | Epigenomics Ag | A method to identify a biological sample for methylation analysis |
| US8748103B2 (en) * | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| SG195652A1 (en) * | 2008-11-07 | 2013-12-30 | Sequenta Inc | Methods of monitoring conditions by sequence analysis |
| JP6158080B2 (en) * | 2010-05-06 | 2017-07-05 | アダプティヴ バイオテクノロジーズ コーポレーション | Health and disease status monitoring using chronotype profiles |
| EP2652155B1 (en) * | 2010-12-16 | 2016-11-16 | Gigagen, Inc. | Methods for massively parallel analysis of nucleic acids in single cells |
-
2013
- 2013-04-09 SG SG11201406538VA patent/SG11201406538VA/en unknown
- 2013-04-09 WO PCT/US2013/035857 patent/WO2013155119A1/en active Application Filing
- 2013-04-09 CN CN201380031219.1A patent/CN104395481A/en active Pending
- 2013-04-09 AU AU2013246050A patent/AU2013246050B2/en active Active
- 2013-04-09 EP EP13775514.6A patent/EP2836611A4/en not_active Withdrawn
- 2013-04-09 JP JP2015505861A patent/JP2015512655A/en active Pending
- 2013-04-09 CA CA2869481A patent/CA2869481A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2836611A1 (en) | 2015-02-18 |
| EP2836611A4 (en) | 2015-12-30 |
| JP2015512655A (en) | 2015-04-30 |
| CA2869481A1 (en) | 2013-10-17 |
| AU2013246050A1 (en) | 2014-10-23 |
| CN104395481A (en) | 2015-03-04 |
| AU2013246050B2 (en) | 2017-03-16 |
| WO2013155119A1 (en) | 2013-10-17 |
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