SG11201401996TA - Pak inhibitors for the treatment of fragile x syndrome - Google Patents
Pak inhibitors for the treatment of fragile x syndromeInfo
- Publication number
- SG11201401996TA SG11201401996TA SG11201401996TA SG11201401996TA SG11201401996TA SG 11201401996T A SG11201401996T A SG 11201401996TA SG 11201401996T A SG11201401996T A SG 11201401996TA SG 11201401996T A SG11201401996T A SG 11201401996TA SG 11201401996T A SG11201401996T A SG 11201401996TA
- Authority
- SG
- Singapore
- Prior art keywords
- fragile
- syndrome
- treatment
- pak inhibitors
- pak
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161555902P | 2011-11-04 | 2011-11-04 | |
| PCT/US2012/063426 WO2013067434A1 (en) | 2011-11-04 | 2012-11-02 | Pak inhibitors for the treatment of fragile x syndrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201401996TA true SG11201401996TA (en) | 2014-05-29 |
Family
ID=48192852
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201401996TA SG11201401996TA (en) | 2011-11-04 | 2012-11-02 | Pak inhibitors for the treatment of fragile x syndrome |
| SG11201401914WA SG11201401914WA (en) | 2011-11-04 | 2012-11-02 | Pak inhibitors for the treatment of cell proliferative disorders |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201401914WA SG11201401914WA (en) | 2011-11-04 | 2012-11-02 | Pak inhibitors for the treatment of cell proliferative disorders |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US20150031693A1 (en) |
| EP (2) | EP2773642A1 (en) |
| JP (2) | JP2014532724A (en) |
| KR (2) | KR20140096098A (en) |
| CN (2) | CN104039786A (en) |
| AR (1) | AR089175A1 (en) |
| AU (2) | AU2012327187A1 (en) |
| BR (2) | BR112014010420A2 (en) |
| CA (2) | CA2854462A1 (en) |
| CL (2) | CL2014001131A1 (en) |
| CO (1) | CO7030960A2 (en) |
| CR (2) | CR20140250A (en) |
| EA (2) | EA201490927A1 (en) |
| IL (2) | IL232154A0 (en) |
| MA (2) | MA35661B1 (en) |
| MX (2) | MX2014005296A (en) |
| PH (1) | PH12014500995A1 (en) |
| SG (2) | SG11201401996TA (en) |
| TW (1) | TW201326169A (en) |
| WO (2) | WO2013067423A1 (en) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130252967A1 (en) * | 2010-06-10 | 2013-09-26 | Afraxis, Inc. | 8-(sulfonylbenzyl)pyrido[2,3-d]pyrimidin-7(8h)-ones for the treatment of cns disorders |
| KR20140088194A (en) | 2011-11-04 | 2014-07-09 | 에프. 호프만-라 로슈 아게 | New aryl-quinoline derivatives |
| JP6576325B2 (en) | 2013-03-15 | 2019-09-18 | セルジーン シーエーアール エルエルシー | Heteroaryl compounds and their use |
| NZ711376A (en) | 2013-03-15 | 2020-01-31 | Sanofi Sa | Heteroaryl compounds and uses thereof |
| AR095464A1 (en) | 2013-03-15 | 2015-10-21 | Celgene Avilomics Res Inc | HETEROARILO COMPOUNDS AND USES OF THE SAME |
| WO2015011252A1 (en) * | 2013-07-26 | 2015-01-29 | F. Hoffmann-La Roche Ag | Pyrimidine-pyridinone serine/threonine kinase inhibitors |
| SI3102577T1 (en) * | 2014-02-07 | 2019-03-29 | Principia Biopharma Inc. | Quinolone derivatives as fibroblast growth factor receptor inhibitors |
| CN105294681B (en) | 2014-07-26 | 2017-07-07 | 广东东阳光药业有限公司 | Compound of CDK type small molecular inhibitors and application thereof |
| US20170042806A1 (en) | 2015-04-29 | 2017-02-16 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
| CA3013959A1 (en) * | 2016-02-17 | 2017-08-24 | Nuralogix Corporation | System and method for detecting physiological state |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
| CN109415366B (en) * | 2016-06-23 | 2022-02-22 | 豪夫迈·罗氏有限公司 | [1,2,3] triazolo [4,5-d ] pyrimidine derivatives |
| US11685954B2 (en) * | 2016-07-15 | 2023-06-27 | Dana-Farber Cancer Institute, Inc. | Biomarkers predictive of endocrine resistance in breast cancer |
| CN106818805A (en) * | 2016-12-27 | 2017-06-13 | 东莞市联洲知识产权运营管理有限公司 | A kind of natural acetylcholinesteraseinhibitors inhibitors and its pesticidal applications |
| CN107083428B (en) * | 2017-04-10 | 2020-09-25 | 徐州医科大学 | Application of PAK5 in cancer diagnosis prognosis treatment and drug screening |
| US20220002429A1 (en) * | 2018-10-24 | 2022-01-06 | Northwestern University | Tumor cell aggregation inhibitors' for treating cancer |
| TWI748317B (en) * | 2019-01-03 | 2021-12-01 | 美商建南德克公司 | Pyrido-pyrimidinone and pteridinone compounds and methods of use |
| CN112213400B (en) * | 2019-07-09 | 2022-06-07 | 四川弘合生物科技有限公司 | Method for detecting beta-elemene and related substances thereof |
| CN110496128B (en) * | 2019-09-23 | 2022-09-30 | 吉林大学 | Application of risperidone or paliperidone in preparation of drugs for treating diffuse large B cell lymphoma |
| AU2021381949A1 (en) | 2020-11-18 | 2023-06-15 | Deciphera Pharmaceuticals, Llc | Gcn2 and perk kinase inhibitors and methods of use thereof |
| CN117858879A (en) * | 2021-01-15 | 2024-04-09 | 南京再明医药有限公司 | CDK2/4/6 inhibitor and preparation method and application thereof |
| CN113046323A (en) * | 2021-04-02 | 2021-06-29 | 四川农业大学 | Method for regulating and controlling ovarian granulosa cells based on miR-532-5p and target genes thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1201765A3 (en) * | 2000-10-16 | 2003-08-27 | Axxima Pharmaceuticals Aktiengesellschaft | Cellular kinases involved in cytomegalovirus infection and their inhibition |
| CA2668731A1 (en) * | 2006-11-09 | 2008-05-15 | Tobias Gabriel | Kinase inhibitors and methods for using the same |
| EP2112150B1 (en) * | 2008-04-22 | 2013-10-16 | Forma Therapeutics, Inc. | Improved raf inhibitors |
| US8674095B2 (en) * | 2008-12-19 | 2014-03-18 | Afraxis Holdings, Inc. | Compounds for treating neuropsychiatric conditions |
| KR20120104200A (en) * | 2009-10-09 | 2012-09-20 | 아프락시스 인코포레이티드 | 8-ethyl-6-(aryl)pyrido[2,3-d]pyrimidin-7(8h)-ones for the treatment of cns disorders |
| WO2011156646A2 (en) * | 2010-06-09 | 2011-12-15 | Afraxis, Inc. | 6-(sulfonylaryl)pyrido[2,3-d]pyrimidin-7(8h)-ones for the treatment of cns disorders |
| US20130252967A1 (en) * | 2010-06-10 | 2013-09-26 | Afraxis, Inc. | 8-(sulfonylbenzyl)pyrido[2,3-d]pyrimidin-7(8h)-ones for the treatment of cns disorders |
-
2012
- 2012-11-02 AU AU2012327187A patent/AU2012327187A1/en not_active Abandoned
- 2012-11-02 US US14/356,118 patent/US20150031693A1/en not_active Abandoned
- 2012-11-02 WO PCT/US2012/063413 patent/WO2013067423A1/en active Application Filing
- 2012-11-02 KR KR1020147014683A patent/KR20140096098A/en not_active Application Discontinuation
- 2012-11-02 MX MX2014005296A patent/MX2014005296A/en not_active Application Discontinuation
- 2012-11-02 CN CN201280066130.4A patent/CN104039786A/en active Pending
- 2012-11-02 EA EA201490927A patent/EA201490927A1/en unknown
- 2012-11-02 BR BR112014010420A patent/BR112014010420A2/en not_active Application Discontinuation
- 2012-11-02 CA CA2854462A patent/CA2854462A1/en not_active Abandoned
- 2012-11-02 EP EP12844804.0A patent/EP2773642A1/en not_active Ceased
- 2012-11-02 JP JP2014540152A patent/JP2014532724A/en active Pending
- 2012-11-02 AU AU2012327183A patent/AU2012327183A1/en not_active Abandoned
- 2012-11-02 SG SG11201401996TA patent/SG11201401996TA/en unknown
- 2012-11-02 EA EA201490925A patent/EA201490925A1/en unknown
- 2012-11-02 JP JP2014540157A patent/JP2015501786A/en active Pending
- 2012-11-02 CN CN201280066127.2A patent/CN104093717A/en active Pending
- 2012-11-02 MX MX2014005292A patent/MX2014005292A/en not_active Application Discontinuation
- 2012-11-02 EP EP12845870.0A patent/EP2773643A4/en not_active Withdrawn
- 2012-11-02 SG SG11201401914WA patent/SG11201401914WA/en unknown
- 2012-11-02 BR BR112014010631A patent/BR112014010631A2/en not_active Application Discontinuation
- 2012-11-02 WO PCT/US2012/063426 patent/WO2013067434A1/en active Application Filing
- 2012-11-02 KR KR1020147014685A patent/KR20140105451A/en not_active Application Discontinuation
- 2012-11-02 CA CA2854471A patent/CA2854471A1/en not_active Abandoned
- 2012-11-02 US US13/668,079 patent/US20130116263A1/en not_active Abandoned
- 2012-11-05 TW TW101141080A patent/TW201326169A/en unknown
- 2012-11-05 AR ARP120104155A patent/AR089175A1/en unknown
-
2014
- 2014-04-22 IL IL232154A patent/IL232154A0/en unknown
- 2014-04-24 IL IL232215A patent/IL232215A0/en unknown
- 2014-04-30 CL CL2014001131A patent/CL2014001131A1/en unknown
- 2014-04-30 CL CL2014001132A patent/CL2014001132A1/en unknown
- 2014-05-02 PH PH12014500995A patent/PH12014500995A1/en unknown
- 2014-05-26 CR CR20140250A patent/CR20140250A/en unknown
- 2014-05-26 MA MA37065A patent/MA35661B1/en unknown
- 2014-05-26 CR CR20140251A patent/CR20140251A/en unknown
- 2014-05-26 MA MA37064A patent/MA35660B1/en unknown
- 2014-06-04 CO CO14119704A patent/CO7030960A2/en unknown
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