SG10201804469RA - Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods - Google Patents
Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methodsInfo
- Publication number
- SG10201804469RA SG10201804469RA SG10201804469RA SG10201804469RA SG10201804469RA SG 10201804469R A SG10201804469R A SG 10201804469RA SG 10201804469R A SG10201804469R A SG 10201804469RA SG 10201804469R A SG10201804469R A SG 10201804469RA SG 10201804469R A SG10201804469R A SG 10201804469RA
- Authority
- SG
- Singapore
- Prior art keywords
- variants
- methods
- timp
- compositions
- tissue inhibitor
- Prior art date
Links
- 102000005876 Tissue Inhibitor of Metalloproteinases Human genes 0.000 title abstract 2
- 108010005246 Tissue Inhibitor of Metalloproteinases Proteins 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 102000005406 Tissue Inhibitor of Metalloproteinase-3 Human genes 0.000 title 1
- 108010031429 Tissue Inhibitor of Metalloproteinase-3 Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
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- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
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- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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- Pharmacology & Pharmacy (AREA)
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- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361782613P | 2013-03-14 | 2013-03-14 | |
| US201361798160P | 2013-03-15 | 2013-03-15 | |
| US201361802988P | 2013-03-18 | 2013-03-18 | |
| US201461940673P | 2014-02-17 | 2014-02-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201804469RA true SG10201804469RA (en) | 2018-06-28 |
Family
ID=50473803
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201804469RA SG10201804469RA (en) | 2013-03-14 | 2014-03-13 | Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods |
| SG11201507524TA SG11201507524TA (en) | 2013-03-14 | 2014-03-13 | Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201507524TA SG11201507524TA (en) | 2013-03-14 | 2014-03-13 | Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US10189890B2 (ko) |
| EP (1) | EP2970407B1 (ko) |
| JP (5) | JP2016513666A (ko) |
| KR (1) | KR102258564B1 (ko) |
| CN (2) | CN111499733A (ko) |
| AP (1) | AP2015008729A0 (ko) |
| AU (5) | AU2014236683B2 (ko) |
| BR (1) | BR112015022491A2 (ko) |
| CA (1) | CA2906053C (ko) |
| CL (1) | CL2015002663A1 (ko) |
| EA (1) | EA034200B1 (ko) |
| HK (1) | HK1219959A1 (ko) |
| IL (1) | IL241246B (ko) |
| MX (1) | MX2015012891A (ko) |
| PE (1) | PE20151894A1 (ko) |
| PH (1) | PH12015502059A1 (ko) |
| SG (2) | SG10201804469RA (ko) |
| TN (1) | TN2015000423A1 (ko) |
| TW (3) | TW201726725A (ko) |
| WO (1) | WO2014152012A2 (ko) |
| ZA (2) | ZA201506746B (ko) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105764523A (zh) * | 2013-09-18 | 2016-07-13 | 詹姆斯库克大学 | 抗炎蛋白及使用方法 |
| AU2015256082C1 (en) | 2014-05-07 | 2020-09-10 | Amgen Inc. | Autoinjector with shock reducing elements |
| CN112237662B (zh) | 2014-06-03 | 2022-10-21 | 安姆根有限公司 | 药物递送系统和使用方法 |
| JP6672257B2 (ja) * | 2014-08-27 | 2020-03-25 | アムジエン・インコーポレーテツド | 組織メタロプロテイナーゼ阻害物質３型（ｔｉｍｐ−３）の変異体、組成物、及び方法 |
| AU2015332557B2 (en) | 2014-10-14 | 2020-05-14 | Amgen Inc. | Drug injection device with visual and audio indicators |
| ES2785311T3 (es) | 2014-12-19 | 2020-10-06 | Amgen Inc | Dispositivo de administración de fármacos con botón móvil o campo de interfaz de usuario |
| CA2976935C (en) | 2015-02-17 | 2020-03-10 | Amgen Inc. | Drug delivery device with vacuum assisted securement and/or feedback |
| ES2905870T3 (es) | 2015-02-27 | 2022-04-12 | Amgen Inc | Dispositivo de suministro de fármacos que tiene un mecanismo de protección de aguja con un umbral de resistencia ajustable al movimiento de la protección de aguja |
| WO2017039786A1 (en) | 2015-09-02 | 2017-03-09 | Amgen Inc. | Syringe assembly adapter for a syringe |
| WO2017100501A1 (en) | 2015-12-09 | 2017-06-15 | Amgen Inc. | Auto-injector with signaling cap |
| WO2017120178A1 (en) | 2016-01-06 | 2017-07-13 | Amgen Inc. | Auto-injector with signaling electronics |
| EP3429663B1 (en) | 2016-03-15 | 2020-07-15 | Amgen Inc. | Reducing probability of glass breakage in drug delivery devices |
| WO2017189089A1 (en) | 2016-04-29 | 2017-11-02 | Amgen Inc. | Drug delivery device with messaging label |
| WO2017192287A1 (en) | 2016-05-02 | 2017-11-09 | Amgen Inc. | Syringe adapter and guide for filling an on-body injector |
| MX2018013616A (es) | 2016-05-13 | 2019-02-21 | Amgen Inc | Montaje de cubierta protectora de vial. |
| US11238150B2 (en) | 2016-05-16 | 2022-02-01 | Amgen Inc. | Data encryption in medical devices with limited computational capability |
| WO2017209899A1 (en) | 2016-06-03 | 2017-12-07 | Amgen Inc. | Impact testing apparatuses and methods for drug delivery devices |
| WO2018004842A1 (en) | 2016-07-01 | 2018-01-04 | Amgen Inc. | Drug delivery device having minimized risk of component fracture upon impact events |
| US20190328965A1 (en) | 2016-08-17 | 2019-10-31 | Amgen Inc. | Drug delivery device with placement detection |
| EP3532127A1 (en) | 2016-10-25 | 2019-09-04 | Amgen Inc. | On-body injector |
| AU2018210301A1 (en) | 2017-01-17 | 2019-08-01 | Amgen Inc. | Injection devices and related methods of use and assembly |
| WO2018151890A1 (en) | 2017-02-17 | 2018-08-23 | Amgen Inc. | Drug delivery device with sterile fluid flowpath and related method of assembly |
| MX2019009755A (es) | 2017-02-17 | 2019-10-07 | Amgen Inc | Mecanismo de insercion para dispositivo de suministro de farmacos. |
| EP3592403A1 (en) | 2017-03-06 | 2020-01-15 | Amgen Inc. | Drug delivery device with activation prevention feature |
| IL268478B2 (en) | 2017-03-07 | 2023-10-01 | Amgen Inc | Inserting a needle using super pressure |
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| EP4241807A3 (en) | 2017-03-28 | 2023-10-11 | Amgen Inc. | Plunger rod and syringe assembly system and method |
| AU2018282077B2 (en) | 2017-06-08 | 2023-11-23 | Amgen Inc. | Torque driven drug delivery device |
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| EP4085942A1 (en) | 2017-07-25 | 2022-11-09 | Amgen Inc. | Drug delivery device with gear module and related method of assembly |
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| US6562596B1 (en) * | 1993-10-06 | 2003-05-13 | Amgen Inc. | Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods |
| JPH09235300A (ja) * | 1996-02-29 | 1997-09-09 | Fuji Yakuhin Kogyo Kk | ヒトｔｉｍｐ−３及び抗ヒトｔｉｍｐ−３モノクローナル抗体並びにその用途 |
| JP5025045B2 (ja) * | 2001-02-02 | 2012-09-12 | マルホ株式会社 | 多硫酸化多糖類によるｔｉｍｐ産生の亢進 |
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