SG10201401864VA - Small Molecules Supporting Pluripotent Cell Growth And Methods Thereof - Google Patents

Small Molecules Supporting Pluripotent Cell Growth And Methods Thereof

Info

Publication number
SG10201401864VA
SG10201401864VA SG10201401864VA SG10201401864VA SG10201401864VA SG 10201401864V A SG10201401864V A SG 10201401864VA SG 10201401864V A SG10201401864V A SG 10201401864VA SG 10201401864V A SG10201401864V A SG 10201401864VA SG 10201401864V A SG10201401864V A SG 10201401864VA
Authority
SG
Singapore
Prior art keywords
methods
cell growth
small molecules
pluripotent cell
molecules supporting
Prior art date
Application number
SG10201401864VA
Inventor
Thomas C Schulz
Allan J Robins
Original Assignee
Viacyte Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US17299809P priority Critical
Application filed by Viacyte Inc filed Critical Viacyte Inc
Publication of SG10201401864VA publication Critical patent/SG10201401864VA/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602Vertebrate cells
    • C12N5/0607Non-embryonic pluripotent stem cells, e.g. MASC
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/105Insulin-like growth factors [IGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/16Activin; Inhibin; Mullerian inhibiting substance
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/195Heregulin, neu differentiation factor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/80Neurotransmitters; Neurohormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/80Neurotransmitters; Neurohormones
    • C12N2501/805Acetylcholine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/80Neurotransmitters; Neurohormones
    • C12N2501/825Serotonine (5-HT); Melatonine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/80Neurotransmitters; Neurohormones
    • C12N2501/845Gamma amino butyric acid [GABA]
SG10201401864VA 2009-04-27 2010-04-27 Small Molecules Supporting Pluripotent Cell Growth And Methods Thereof SG10201401864VA (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US17299809P true 2009-04-27 2009-04-27

Publications (1)

Publication Number Publication Date
SG10201401864VA true SG10201401864VA (en) 2014-09-26

Family

ID=43050738

Family Applications (2)

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SG2011078813A SG175367A1 (en) 2009-04-27 2010-04-27 Small molecules supporting pluripotent cell growth and methods thereof
SG10201401864VA SG10201401864VA (en) 2009-04-27 2010-04-27 Small Molecules Supporting Pluripotent Cell Growth And Methods Thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG2011078813A SG175367A1 (en) 2009-04-27 2010-04-27 Small molecules supporting pluripotent cell growth and methods thereof

Country Status (5)

Country Link
US (2) US8685726B2 (en)
JP (2) JP5961110B2 (en)
CN (2) CN107603943B (en)
SG (2) SG175367A1 (en)
WO (1) WO2010129294A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9109245B2 (en) 2009-04-22 2015-08-18 Viacyte, Inc. Cell compositions derived from dedifferentiated reprogrammed cells
WO2014124172A1 (en) * 2013-02-06 2014-08-14 Viacyte, Inc. Cell compositions derived from dedifferentiated reprogrammed cells
CN107603943B (en) 2009-04-27 2019-10-11 威盛细胞有限公司 Support the small molecule and its method of pluripotent cell growth
WO2011058558A2 (en) 2009-11-12 2011-05-19 Technion Research & Development Foundation Ltd. Culture media, cell cultures and methods of culturing pluripotent stem cells in an undifferentiated state
US9433557B2 (en) 2011-02-21 2016-09-06 Viacyte, Inc. Loading system for an encapsulation device
WO2013151186A1 (en) * 2012-04-06 2013-10-10 国立大学法人京都大学 Method for inducing erythropoietin-producing cell
CA2913990A1 (en) * 2013-05-30 2014-12-04 Ajinomoto Co., Inc. Medium for culturing stem cells
RU2016100219A3 (en) 2013-06-11 2018-03-30
CN103361310B (en) * 2013-06-25 2015-09-23 中国人民解放军军事医学科学院野战输血研究所 Substratum, test kit and uses thereof
CN105518458B (en) * 2013-06-26 2018-07-17 瓦里泰细胞有限公司 The method for determining or predicting cell characteristic
EP3128003A4 (en) * 2014-03-31 2017-08-16 Ajinomoto Co., Inc. Medium for stem cell use
EP2944958A1 (en) * 2014-04-04 2015-11-18 Techno-Path (Distribution) A method of predicting phenotypic instability in a cell
GB201421094D0 (en) * 2014-11-27 2015-01-14 Koninklijke Nederlandse Akademie Van Wetenschappen Culture medium
GB201421092D0 (en) * 2014-11-27 2015-01-14 Koninklijke Nederlandse Akademie Van Wetenschappen Culture medium
CN107614678A (en) 2014-12-18 2018-01-19 哈佛学院校长同事会 The production method and its application method of the β cells of source of human stem cell
EP3234110A4 (en) 2014-12-18 2018-06-27 President and Fellows of Harvard College METHODS FOR GENERATING STEM CELL-DERIVED ß CELLS AND USES THEREOF
WO2016100898A1 (en) 2014-12-18 2016-06-23 President And Fellows Of Harvard College Serum-free in vitro directed differentiation protocol for generating stem cell-derived b cells and uses thereof
CN104830753B (en) * 2015-05-20 2018-07-10 广州赛莱拉干细胞科技股份有限公司 A kind of induced multi-potent stem cell culture medium, application and cultural method
CN106479978A (en) * 2015-10-14 2017-03-08 北京昱龙盛世生物科技有限公司 A kind of special culture media of neural stem cell and its cultural method
US10391156B2 (en) 2017-07-12 2019-08-27 Viacyte, Inc. University donor cells and related methods

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4223961B2 (en) * 2002-01-31 2009-02-12 Agcテクノグラス株式会社 Method of cryopreserving primate embryonic stem cells
US20040121464A1 (en) * 2002-09-30 2004-06-24 Rathjen Peter David Method for the preparation of cells of mesodermal lineage
US8153429B2 (en) * 2006-02-23 2012-04-10 Viacyte, Inc. Compositions and methods useful for culturing differentiable cells
JP5199253B2 (en) * 2006-06-22 2013-05-15 イエダ リサーチ アンド ディベロップメント カンパニー リミテッド Regulation of catecholamine receptors
CN101970642A (en) * 2007-09-04 2011-02-09 昆士兰技术大学 A feeder cell-free culture medium and system
CN107603943B (en) 2009-04-27 2019-10-11 威盛细胞有限公司 Support the small molecule and its method of pluripotent cell growth

Also Published As

Publication number Publication date
SG175367A1 (en) 2011-11-28
CN107603943A (en) 2018-01-19
WO2010129294A2 (en) 2010-11-11
US20120021513A1 (en) 2012-01-26
JP5961110B2 (en) 2016-08-02
US20140186948A1 (en) 2014-07-03
JP2016187347A (en) 2016-11-04
WO2010129294A3 (en) 2011-04-21
CN102741396B (en) 2017-10-20
JP6343302B2 (en) 2018-06-13
US9458426B2 (en) 2016-10-04
US8685726B2 (en) 2014-04-01
CN102741396A (en) 2012-10-17
JP2012525148A (en) 2012-10-22
CN107603943B (en) 2019-10-11

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