SE8602737L - Forfarande for framstellning av 2-halonicergolin-derivat och deras syraadditionssalter och nya 2-halonicergliner - Google Patents

Forfarande for framstellning av 2-halonicergolin-derivat och deras syraadditionssalter och nya 2-halonicergliner

Info

Publication number
SE8602737L
SE8602737L SE8602737A SE8602737A SE8602737L SE 8602737 L SE8602737 L SE 8602737L SE 8602737 A SE8602737 A SE 8602737A SE 8602737 A SE8602737 A SE 8602737A SE 8602737 L SE8602737 L SE 8602737L
Authority
SE
Sweden
Prior art keywords
acid addition
derivatives
preparation
addition salts
formula
Prior art date
Application number
SE8602737A
Other languages
English (en)
Other versions
SE8602737D0 (sv
SE463716B (sv
Inventor
G Megyeri
T Keve
B Stefko
E Bogsch
J Galambos
A Kassai
F Trischler
E Palosi
D Groo
E Karpati
Z Szombathelyi
L Szporny
B Kiss
I Laszlovszky
E Lapis
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of SE8602737D0 publication Critical patent/SE8602737D0/sv
Publication of SE8602737L publication Critical patent/SE8602737L/sv
Publication of SE463716B publication Critical patent/SE463716B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8602737A 1985-06-21 1986-06-19 2-halonicergolinderivat, foerfarande foer framstaellning av detta och en farmaceutisk beredning SE463716B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU852447A HU193782B (en) 1985-06-21 1985-06-21 Process for producing 2-halogeno-nicergoline derivatives and acid additional salts thereof

Publications (3)

Publication Number Publication Date
SE8602737D0 SE8602737D0 (sv) 1986-06-19
SE8602737L true SE8602737L (sv) 1986-12-22
SE463716B SE463716B (sv) 1991-01-14

Family

ID=10959403

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8602737A SE463716B (sv) 1985-06-21 1986-06-19 2-halonicergolinderivat, foerfarande foer framstaellning av detta och en farmaceutisk beredning

Country Status (30)

Country Link
US (1) US4753949A (sv)
JP (1) JPS62485A (sv)
CN (1) CN1015365B (sv)
AR (1) AR241533A1 (sv)
AT (1) AT390614B (sv)
AU (1) AU594686B2 (sv)
BE (1) BE904957A (sv)
CH (1) CH671018A5 (sv)
CS (1) CS255875B1 (sv)
DD (1) DD246111A5 (sv)
DE (1) DE3620647A1 (sv)
DK (1) DK292086A (sv)
ES (1) ES8800953A1 (sv)
FI (1) FI84605C (sv)
FR (1) FR2583756B1 (sv)
GB (1) GB2176788B (sv)
HU (1) HU193782B (sv)
IL (1) IL79179A0 (sv)
IN (1) IN163116B (sv)
IT (1) IT1204865B (sv)
LU (1) LU86485A1 (sv)
NL (1) NL8601612A (sv)
NO (1) NO164099C (sv)
PH (1) PH24732A (sv)
PL (1) PL147390B1 (sv)
PT (1) PT82808B (sv)
SE (1) SE463716B (sv)
SU (1) SU1445557A3 (sv)
YU (1) YU107986A (sv)
ZA (1) ZA864633B (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU193781B (en) * 1985-06-21 1987-11-30 Richter Gedeon Vegyeszet Process for producing 10alpha-methoxy-6-methylergoline derivatives and acid additional salts thereof
HU196394B (en) * 1986-06-27 1988-11-28 Richter Gedeon Vegyeszet Process for preparing 2-halogenated ergoline derivatives

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3228943A (en) * 1962-06-11 1966-01-11 Lumilysergol derivatives
US3879554A (en) * 1970-03-20 1975-04-22 Farmaceutici Italia Use of 1,6-dimethyl-8-{62 -(5-bromonicotinoyloxymethyl)-10 {60 -methoxyergoline in treating cerebral and peripheral metabolic vascular disorders
US4199579A (en) * 1975-03-14 1980-04-22 Siphar S. A. Carbamates of 2-haloergolines and 2-haloergolenes and process for the preparation thereof
GB1513322A (en) * 1976-01-09 1978-06-07 Farmaceutici Italia Heterocyclic ergoline derivatives
YU39278B (en) * 1976-12-22 1984-10-31 Lek Tovarna Farmacevtskih Process for preparing 5-bromo nicotinic acid esters
IT1094965B (it) * 1978-04-05 1985-08-10 Corvi Mora E Procedimento di preparazione di derivati del lisergolo
EP0091652B1 (en) * 1982-04-13 1986-02-26 FARMITALIA CARLO ERBA S.p.A. Ergoline derivatives, process for producing the ergoline derivatives and pharmaceutical compositions containing them
CH649998A5 (de) * 1982-08-09 1985-06-28 Sandoz Ag Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.
GB8612366D0 (en) * 1986-05-21 1986-06-25 Erba Farmitalia Ergoline esters
GB8615471D0 (en) * 1986-06-25 1986-07-30 Erba Farmitalia T-butyl ergoline derivatives

Also Published As

Publication number Publication date
IT1204865B (it) 1989-03-10
NO164099B (no) 1990-05-21
SE8602737D0 (sv) 1986-06-19
NL8601612A (nl) 1987-01-16
DD246111A5 (de) 1987-05-27
YU107986A (en) 1988-04-30
BE904957A (fr) 1986-12-19
NO164099C (no) 1990-08-29
ES8800953A1 (es) 1987-12-16
CH671018A5 (sv) 1989-07-31
ES556359A0 (es) 1987-12-16
PT82808B (pt) 1988-04-21
JPH0529227B2 (sv) 1993-04-28
ATA168486A (de) 1989-11-15
SE463716B (sv) 1991-01-14
FI862635A0 (fi) 1986-06-19
CS255875B1 (en) 1988-03-15
IN163116B (sv) 1988-08-13
GB2176788B (en) 1989-07-26
FR2583756B1 (fr) 1990-01-12
AU594686B2 (en) 1990-03-15
GB8615120D0 (en) 1986-07-23
IL79179A0 (en) 1986-09-30
NO862493D0 (no) 1986-06-20
LU86485A1 (de) 1986-12-02
PL147390B1 (en) 1989-05-31
PT82808A (en) 1986-07-01
ZA864633B (en) 1987-02-25
HU193782B (en) 1987-11-30
FI862635A (fi) 1986-12-22
DE3620647A1 (de) 1987-01-02
AT390614B (de) 1990-06-11
AR241533A1 (es) 1992-08-31
CN1015365B (zh) 1992-02-05
FI84605B (fi) 1991-09-13
JPS62485A (ja) 1987-01-06
PH24732A (en) 1990-10-01
FR2583756A1 (fr) 1986-12-26
NO862493L (no) 1986-12-22
AU5891686A (en) 1986-12-24
CN86104086A (zh) 1986-12-17
HUT41024A (en) 1987-03-30
GB2176788A (en) 1987-01-07
DK292086D0 (da) 1986-06-20
SU1445557A3 (ru) 1988-12-15
US4753949A (en) 1988-06-28
IT8620873A0 (it) 1986-06-20
DK292086A (da) 1986-12-22
FI84605C (sv) 1991-12-27

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