SE8306714L - Forfarande for framstellning av l-karnitin och herfor anvenda kemiska mellanprodukter - Google Patents

Forfarande for framstellning av l-karnitin och herfor anvenda kemiska mellanprodukter

Info

Publication number
SE8306714L
SE8306714L SE8306714A SE8306714A SE8306714L SE 8306714 L SE8306714 L SE 8306714L SE 8306714 A SE8306714 A SE 8306714A SE 8306714 A SE8306714 A SE 8306714A SE 8306714 L SE8306714 L SE 8306714L
Authority
SE
Sweden
Prior art keywords
hydroxybutyrate
converting
carnitine
salt
chemical intermediates
Prior art date
Application number
SE8306714A
Other languages
English (en)
Swedish (sv)
Other versions
SE8306714D0 (sv
SE455501B (sv
Inventor
C J Sih
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/447,171 external-priority patent/US4642290A/en
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of SE8306714D0 publication Critical patent/SE8306714D0/xx
Publication of SE8306714L publication Critical patent/SE8306714L/
Publication of SE455501B publication Critical patent/SE455501B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/24Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26Ketones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE8306714A 1982-12-06 1983-12-05 Optiskt aktiva gamma-substituerade beta-hydroxismorsyraderivat samt forfarande for framstellning av dessa genom fermentativ enzymatisk verkan av en mikroorganism SE455501B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/447,171 US4642290A (en) 1982-12-06 1982-12-06 Process for preparing a compound for use in the production of L-carnitine
US54495783A 1983-10-24 1983-10-24

Publications (3)

Publication Number Publication Date
SE8306714D0 SE8306714D0 (sv) 1983-12-05
SE8306714L true SE8306714L (sv) 1984-06-07
SE455501B SE455501B (sv) 1988-07-18

Family

ID=27034888

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8306714A SE455501B (sv) 1982-12-06 1983-12-05 Optiskt aktiva gamma-substituerade beta-hydroxismorsyraderivat samt forfarande for framstellning av dessa genom fermentativ enzymatisk verkan av en mikroorganism

Country Status (23)

Country Link
JP (1) JPH0767674A ( )
KR (1) KR840008165A ( )
AT (1) AT393136B ( )
AU (1) AU566906B2 ( )
CA (1) CA1225956A ( )
CH (1) CH661498A5 ( )
DE (1) DE3344085C2 ( )
DK (1) DK163917C ( )
ES (1) ES8601305A1 ( )
FI (1) FI81115C ( )
FR (1) FR2537130B1 ( )
GB (1) GB2132614B ( )
GR (1) GR78767B ( )
IE (1) IE56322B1 ( )
IL (1) IL70352A ( )
IT (1) IT1167289B ( )
LU (1) LU85115A1 ( )
NL (1) NL8304190A ( )
NO (1) NO159291C ( )
PH (1) PH20456A ( )
PT (1) PT77780B ( )
SE (1) SE455501B ( )
TR (1) TR23136A ( )

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK544284A (da) * 1983-12-06 1985-06-07 Hoffmann La Roche Fremgangsmaade til fremstilling af optisk aktive propionsyrederivater
IT1181908B (it) * 1984-07-12 1987-09-30 Debi Derivati Biologici Procedimento per la preparazione di l-carnitina
IT1181812B (it) * 1984-07-27 1987-09-30 Sigma Tau Ind Farmaceuti Procedimento per la preparazione dell'acido gamma-dimetilammino l-beta-idrossibutirrico
IT1190358B (it) * 1985-05-24 1988-02-16 Sclavo Spa Procedimento per la preparazione di l-carnitina
JPS62126997A (ja) * 1985-11-28 1987-06-09 Nippon Synthetic Chem Ind Co Ltd:The 光学活性のγ−ハロ−βヒドロキシ酪酸エステルの製造法
IT1189070B (it) * 1986-03-14 1988-01-28 Donegani Guido Ist Processo per la preparazione della l(-)-carnitina cloruro a partire da esteri 3,4-epossibutirrici
JPH0678277B2 (ja) * 1988-02-19 1994-10-05 高砂香料工業株式会社 光学活性アルコールおよびその誘導体の製造方法
JP2939646B2 (ja) * 1990-07-17 1999-08-25 チッソ株式会社 4―置換―2―ヒドロキシブタン酸エステルおよび製造法
US5215919A (en) * 1991-02-25 1993-06-01 Takeda Chemical Industries, Ltd. Process for producing optically active 2-hydroxycycloalkanecarboxylic acid esters using microbially derived reductase
US5324662A (en) 1992-05-15 1994-06-28 E. R. Squibb & Sons, Inc. Stereoselective microbial or enzymatic reduction of 3,5-dioxo esters to 3-hydroxy-5-oxo, 3-oxo-5-hydroxy, and 3,5-dihydroxy esters
JP3155107B2 (ja) * 1993-01-12 2001-04-09 ダイセル化学工業株式会社 光学活性4−ハロ−3−ヒドロキシ酪酸エステルの製造方法
JP2000189170A (ja) * 1998-05-08 2000-07-11 Daicel Chem Ind Ltd 光学活性4―ハロ―3―ヒドロキシ酪酸エステルの製造方法
EP1024139B1 (en) 1998-08-05 2004-05-12 Kaneka Corporation Process for the preparation of optically active 2-(6-(hydroxymethyl)-1,3-dioxan-4-yl) acetic acid derivatives
CA2493941A1 (en) * 2002-08-09 2004-02-19 Codexis, Inc. Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives
DE10315760A1 (de) * 2003-04-07 2004-10-21 Basf Ag L-Carnitin Dehydrogenasen, deren Derivate und ein Verfahren zur Herstellung von substituierten (S)-Alkanolen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931410A (en) * 1974-02-28 1976-01-06 The Upjohn Company Composition and method of use
CH589604A5 ( ) * 1974-04-26 1977-07-15 Lonza Ag
JPS5139634A (en) * 1974-09-27 1976-04-02 Ono Pharmaceutical Co Ganma amino beeta hidorokishibutansananirido no seizoho
JPS6017776B2 (ja) * 1979-11-07 1985-05-07 電気化学工業株式会社 γ−クロロ−β−ヒドロキシ酪酸アルキルエステルの製法
JPS5950661B2 (ja) * 1980-07-28 1984-12-10 電気化学工業株式会社 γ−アミノ−β−ヒドロキシ酪酸の製造法
JPS5950663B2 (ja) * 1981-04-28 1984-12-10 電気化学工業株式会社 γ−アミノ−β−ヒドロキシ酪酸の製造法

Also Published As

Publication number Publication date
DK163917B (da) 1992-04-21
PT77780B (en) 1986-04-17
GR78767B ( ) 1984-10-02
FI81115B (fi) 1990-05-31
FR2537130B1 (fr) 1988-10-14
NO159291B (no) 1988-09-05
ATA423783A (de) 1991-01-15
KR840008165A (ko) 1984-12-13
ES527807A0 (es) 1985-11-01
PH20456A (en) 1987-01-14
FI81115C (fi) 1990-09-10
CH661498A5 (it) 1987-07-31
IT1167289B (it) 1987-05-13
NL8304190A (nl) 1984-07-02
DK559283A (da) 1984-06-07
FR2537130A1 (fr) 1984-06-08
AU2175883A (en) 1984-06-14
ES8601305A1 (es) 1985-11-01
IL70352A (en) 1987-10-20
FI834419A0 (fi) 1983-12-02
IE832732L (en) 1984-06-06
DK163917C (da) 1992-09-14
AT393136B (de) 1991-08-26
GB2132614B (en) 1986-03-26
DE3344085C2 (de) 1993-10-14
FI834419A (fi) 1984-06-07
SE8306714D0 (sv) 1983-12-05
IL70352A0 (en) 1984-02-29
IE56322B1 (en) 1991-06-19
LU85115A1 (fr) 1984-04-02
CA1225956A (en) 1987-08-25
DK559283D0 (da) 1983-12-05
GB8332359D0 (en) 1984-01-11
JPH0767674A (ja) 1995-03-14
PT77780A (en) 1984-01-01
IT8324018A0 (it) 1983-12-05
NO834461L (no) 1984-06-07
AU566906B2 (en) 1987-11-05
NO159291C (no) 1988-12-14
TR23136A (tr) 1989-04-11
DE3344085A1 (de) 1984-06-07
GB2132614A (en) 1984-07-11
SE455501B (sv) 1988-07-18

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