SE7703979A - 1-nitro-9-dialkylaminoisoalkylamino-acridines, their salts and forward tell up and priority over derav as lekemedel - Google Patents

1-nitro-9-dialkylaminoisoalkylamino-acridines, their salts and forward tell up and priority over derav as lekemedel

Info

Publication number
SE7703979A
SE7703979A SE7703979A SE7703979A SE7703979A SE 7703979 A SE7703979 A SE 7703979A SE 7703979 A SE7703979 A SE 7703979A SE 7703979 A SE7703979 A SE 7703979A SE 7703979 A SE7703979 A SE 7703979A
Authority
SE
Sweden
Prior art keywords
nitro
salts
lekemedel
derav
dialkylaminoisoalkylamino
Prior art date
Application number
SE7703979A
Other languages
Swedish (sv)
Other versions
SE435712B (en
Inventor
A Ledochowski
J Gieldanowski
C Radzikowski
C Kwasniewska-Rokicinska
B Wysocka-Skrzela
L Sawinska
M Medon
Original Assignee
Politechnika Gdanska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to PL18852876A priority Critical patent/PL101032B1/en
Application filed by Politechnika Gdanska filed Critical Politechnika Gdanska
Publication of SE7703979A publication Critical patent/SE7703979A/en
Publication of SE435712B publication Critical patent/SE435712B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08Nitrogen atoms
    • C07D219/10Nitrogen atoms attached in position 9
    • C07D219/12Amino-alkyl-amino radicals attached in position 9

Abstract

1-Nitro-9-dialkylaminoisoalkylaminoacridines or their salts of the formula: <IMAGE> wherein R is lower alkyl, such as methyl, ethyl, R1 is a hydrogen atom or methyl, R2 is the same as R1, with the proviso that R1 is not equal to R2 and n = 0 or 2, and their preparation is described. These compounds are useful as anti-neoplastic agents.
SE7703979A 1976-04-06 1977-04-05 Analogiforfarande for forward tell up of 1-nitro-9-dialkylaminoisoalkylaminoakridiner or salts derav SE435712B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL18852876A PL101032B1 (en) 1976-04-06 1976-04-06 A method for obtaining 1-nitro-9-dialkyl-aminoizoalkiloamiroakrydyn or salts thereof

Publications (2)

Publication Number Publication Date
SE7703979A true SE7703979A (en) 1977-10-07
SE435712B SE435712B (en) 1984-10-15

Family

ID=19976296

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7703979A SE435712B (en) 1976-04-06 1977-04-05 Analogiforfarande for forward tell up of 1-nitro-9-dialkylaminoisoalkylaminoakridiner or salts derav

Country Status (12)

Country Link
US (1) US4150231A (en)
JP (1) JPS5527908B2 (en)
BE (1) BE852855A (en)
CH (1) CH634561A5 (en)
DE (1) DE2713103C2 (en)
FR (1) FR2347350B1 (en)
GB (1) GB1579588A (en)
HU (1) HU173105B (en)
NL (1) NL7703680A (en)
PL (1) PL101032B1 (en)
SE (1) SE435712B (en)
SU (2) SU683617A3 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4335244A (en) * 1979-11-30 1982-06-15 Bristol-Myers Company Monolactate salts of 4'-(9-acridinylamino)methanesulfon-m-anisidide
JPS6332765B2 (en) * 1980-02-15 1988-07-01 Mitsui Toatsu Chemicals
PL126407B1 (en) * 1980-04-23 1983-07-30 Process for preparing 1-nitro-9-hydroxyalkylaminoacridines or their salts
HU186383B (en) * 1981-02-27 1985-07-29 Biogal Gyogyszergyar Process for producing new citostatic amni-acridie-alpha, beta-bracket-d-bracket closed, or aracket-l-bracket closed-n-glycoside derivatives and salts
US4575509A (en) * 1983-01-31 1986-03-11 Bristol-Myers Company Water-soluble formulations of m-AMSA with pyroglutamic acid
US4626540A (en) * 1983-11-08 1986-12-02 Warner-Lambert Company Substituted 1-amino-4-nitro-acridinones and methods of treating bacterial infections and leukemia with them
AT63903T (en) * 1984-10-25 1991-06-15 Hoechst Roussel Pharma 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, processes for their preparation and use as pharmaceuticals.
US6589961B2 (en) 2000-02-18 2003-07-08 New York Medical College 9-alkylamino-1-nitroacridine derivatives
DE60143020D1 (en) * 2000-02-18 2010-10-21 New York Medical College Valha 9-alkylamino-1-NITROACRIDIN DERIVATIVES
AT445838T (en) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Compositions and methods for modulating transport by the blood-brain barrier
JP2008539047A (en) 2005-04-28 2008-11-13 プロテウス バイオメディカル インコーポレイテッド Pharma Informatics System
EP2063905B1 (en) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1962277A (en) * 1927-01-11 1934-06-12 Winthrop Chem Co Inc Basic nitroderivatives of 9-aminoacridines and process for preparing the same
DE1620473C3 (en) * 1964-05-25 1980-03-20 Starogardzkie Zaklady Farmaceutyczne Polfa Przedsiebiorstwo Panstwowe, Starogard Gdanski (Polen)
US3897435A (en) * 1968-08-31 1975-07-29 Starogadzkie Zaklady Farmaceut N-oxides of 1 -nitro-9-dialkylaminoalkylamino/acridine
CH517096A (en) * 1968-08-31 1971-12-31 Starogardzkie Zakl Farma A process for the preparation of new biologically active 1-nitro-9- (dialkyl-aminoalkylamino) -akridin-N10-oxide

Also Published As

Publication number Publication date
NL7703680A (en) 1977-10-10
DE2713103A1 (en) 1977-10-13
SE435712B (en) 1984-10-15
PL101032B1 (en) 1978-11-30
SU682127A3 (en) 1979-08-25
FR2347350B1 (en) 1980-02-01
DE2713103C2 (en) 1982-02-04
CH634561A5 (en) 1983-02-15
FR2347350A1 (en) 1977-11-04
BE852855A (en) 1977-07-18
BE852855A1 (en)
SU683617A3 (en) 1979-08-30
JPS52151178A (en) 1977-12-15
GB1579588A (en) 1980-11-19
US4150231A (en) 1979-04-17
HU173105B (en) 1979-02-28
JPS5527908B2 (en) 1980-07-24

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