SE361174B - - Google Patents

Info

Publication number
SE361174B
SE361174B SE12424/70A SE1242470A SE361174B SE 361174 B SE361174 B SE 361174B SE 12424/70 A SE12424/70 A SE 12424/70A SE 1242470 A SE1242470 A SE 1242470A SE 361174 B SE361174 B SE 361174B
Authority
SE
Sweden
Application number
SE12424/70A
Inventor
E Reeder
A Stempel
L H Sternbach
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US240750A external-priority patent/US3340253A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE361174B publication Critical patent/SE361174B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/20—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Inductance-Capacitance Distribution Constants And Capacitance-Resistance Oscillators (AREA)
SE12424/70A 1962-03-09 1970-09-11 SE361174B (enrdf_load_stackoverflow)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17855162A 1962-03-09 1962-03-09
US240750A US3340253A (en) 1962-11-28 1962-11-28 Preparation of certain benzodiazepine compounds

Publications (1)

Publication Number Publication Date
SE361174B true SE361174B (enrdf_load_stackoverflow) 1973-10-22

Family

ID=26874429

Family Applications (2)

Application Number Title Priority Date Filing Date
SE02566/63A SE328583B (enrdf_load_stackoverflow) 1962-03-09 1963-03-08
SE12424/70A SE361174B (enrdf_load_stackoverflow) 1962-03-09 1970-09-11

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE02566/63A SE328583B (enrdf_load_stackoverflow) 1962-03-09 1963-03-08

Country Status (9)

Country Link
BE (1) BE629227A (enrdf_load_stackoverflow)
CA (1) CA976547A (enrdf_load_stackoverflow)
CH (2) CH442326A (enrdf_load_stackoverflow)
DE (4) DE1545955A1 (enrdf_load_stackoverflow)
DK (1) DK127507B (enrdf_load_stackoverflow)
ES (1) ES285854A1 (enrdf_load_stackoverflow)
GB (2) GB1013900A (enrdf_load_stackoverflow)
NL (3) NL7010711A (enrdf_load_stackoverflow)
SE (2) SE328583B (enrdf_load_stackoverflow)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES405260A1 (es) * 1972-07-28 1975-07-01 Stabilimenti Chim Farmac Riuni Procedimiento para la preparacion de 3-hidroxi-5-aril-7- sustituidos-1, 3-dihidro-2h-1, 4-benzodiacepin-2-onas.
NL173269C (nl) * 1974-04-30 1984-01-02 Ferrer Int Werkwijze voor de bereiding van een geneesmiddel met als werkzaam bestanddeel een 1,4-benzodiazepinederivaat, alsmede werkwijze voor de bereiding van het 1,4-benzodiazepinederivaat.
DE3413592C2 (de) * 1984-04-11 1986-06-05 Dolorgiet GmbH & Co KG, 5205 St Augustin Arzneimittel enthaltend 5-(2-Fluorphenyl)-1,3-dihydro-3-hydroxy-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-on
EP0167920A3 (en) * 1984-06-26 1986-11-05 Merck & Co. Inc. Benzodiazepine derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DE1545956A1 (de) 1969-11-20
ES285854A1 (es) 1963-08-16
SE328583B (enrdf_load_stackoverflow) 1970-09-21
GB1013229A (en) 1965-12-15
NL289735A (enrdf_load_stackoverflow)
DE1545957A1 (de) 1969-12-11
GB1013900A (en) 1965-12-22
CH457464A (de) 1968-06-15
CH442326A (de) 1967-08-31
BE629227A (fr) 1963-10-21
DE1545955A1 (de) 1969-11-20
NL7010711A (enrdf_load_stackoverflow) 1970-10-26
CA976547A (en) 1975-10-21
NL7010712A (enrdf_load_stackoverflow) 1970-10-26
DE1445873A1 (de) 1969-04-10
DK127507B (da) 1973-11-19

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