SE0303270A - Method for administration of tiotropium - Google Patents

Method for administration of tiotropium

Info

Publication number
SE0303270A
SE0303270A SE0303270A SE0303270A SE0303270A SE 0303270 A SE0303270 A SE 0303270A SE 0303270 A SE0303270 A SE 0303270A SE 0303270 A SE0303270 A SE 0303270A SE 0303270 A SE0303270 A SE 0303270A
Authority
SE
Sweden
Prior art keywords
dry powder
dose
delivered
inhaler
administration
Prior art date
Application number
SE0303270A
Other languages
Swedish (sv)
Other versions
SE0303270D0 (en
Inventor
Thomas Nilsson
Mattias Myrman
Sven Calander
Alf Niemi
Original Assignee
Microdrug Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Application filed by Microdrug Ag filed Critical Microdrug Ag
Priority to SE0303270A priority Critical patent/SE0303270A/en
Publication of SE0303270D0 publication Critical patent/SE0303270D0/en
Publication of SE0303270A publication Critical patent/SE0303270A/en
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29778163&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE0303270(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder

Abstract

A method for administration and preparation of pharmaceutical dry powder doses are disclosed. The metered dry powder doses are formed from a finely divided dry powder of an selected anticholinergic agent to be used in a dry powder inhaler device. The metered dry powder medicinal dose is arranged as a medicinally effective quantity of the selected medicament onto a dose bed and moisture-tight sealed by using a high barrier seal, for introduction into an inhaler device provided with an Air-razor device for obtaining a fine particle fraction, FPF, of at least 30-50% of delivered powder mass when suction through the inhaler is applied, whereby the dose is delivered to and deposited in the lung of the user during a single inhalation effort.
SE0303270A 2003-12-03 2003-12-03 Method for administration of tiotropium SE0303270A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SE0303270A SE0303270A (en) 2003-12-03 2003-12-03 Method for administration of tiotropium

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
SE0303270A SE0303270A (en) 2003-12-03 2003-12-03 Method for administration of tiotropium
US10/729,024 US20050121026A1 (en) 2003-12-03 2003-12-08 Method for administration of tiotropium
DE200460024261 DE602004024261D1 (en) 2003-12-03 2004-12-02 A method for administration of tiotropium
SI200431340T SI1991202T1 (en) 2003-12-03 2004-12-02 Method for administration tiotropium
CA 2547660 CA2547660A1 (en) 2003-12-03 2004-12-02 Inhalation administration of tiotropium in high amount of metered dose
PT04801708T PT1991202E (en) 2003-12-03 2004-12-02 Method for administration tiotropium
EP20040801708 EP1991202B1 (en) 2003-12-03 2004-12-02 Method for administration tiotropium
ZA200604254A ZA200604254B (en) 2003-12-03 2004-12-02 Method for administration tiotropium
DK04801708T DK1991202T3 (en) 2003-12-03 2004-12-02 Fremgagsmåde for administration of tiotropium
PCT/SE2004/001791 WO2005053645A1 (en) 2003-12-03 2004-12-02 Method for administration tiotropium
AU2004294887A AU2004294887B2 (en) 2003-12-03 2004-12-02 Method for administration tiotropium
ES04801708T ES2333725T3 (en) 2003-12-03 2004-12-02 Method for administering tiotropium.
AT04801708T AT448776T (en) 2003-12-03 2004-12-02 A method for administration of tiotropium
US11/448,725 US20070110678A1 (en) 2003-12-03 2006-06-08 Method for administration of tiotropium
CY20101100009T CY1110625T1 (en) 2003-12-03 2010-01-05 METHOD to tiotropium

Publications (2)

Publication Number Publication Date
SE0303270D0 SE0303270D0 (en) 2003-12-03
SE0303270A true SE0303270A (en) 2005-06-04

Family

ID=29778163

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0303270A SE0303270A (en) 2003-12-03 2003-12-03 Method for administration of tiotropium

Country Status (14)

Country Link
US (2) US20050121026A1 (en)
EP (1) EP1991202B1 (en)
AT (1) AT448776T (en)
AU (1) AU2004294887B2 (en)
CA (1) CA2547660A1 (en)
CY (1) CY1110625T1 (en)
DE (1) DE602004024261D1 (en)
DK (1) DK1991202T3 (en)
ES (1) ES2333725T3 (en)
PT (1) PT1991202E (en)
SE (1) SE0303270A (en)
SI (1) SI1991202T1 (en)
WO (1) WO2005053645A1 (en)
ZA (1) ZA200604254B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG149876A1 (en) * 2003-11-03 2009-02-27 Boehringer Ingelheim Int Novel tiotropium salts, methods for the production thereof, and pharmaceutical formulations containing the same
PT1682541E (en) * 2003-11-03 2010-04-14 Boehringer Ingelheim Int Method for producing tiotropium salts
SE0303569A (en) * 2003-12-03 2005-06-04 Microdrug Ag DPI delivery of moisture sensitive medicament
SE0303270A (en) * 2003-12-03 2005-06-04 Microdrug Ag Method for administration of tiotropium
SE0303570A (en) * 2003-12-03 2005-06-04 Microdrug Ag Moisture-sensitive medical product
SE0303269A (en) * 2003-12-03 2005-06-04 Microdrug Ag medical product
CA2547782A1 (en) * 2003-12-03 2005-06-16 Microdrug Ag Medical product containing tiotropium
SE0303571D0 (en) * 2003-12-03 2003-12-22 Microdrug Ag Medical product for moisture-sensitive medicaments
TWI274641B (en) * 2005-08-30 2007-03-01 Rexon Ind Corp Ltd Cutting machine
WO2009079078A1 (en) 2007-12-14 2009-06-25 Labogroup S.A.S. Delivering aerosolizable food products
RU2580315C2 (en) * 2009-05-29 2016-04-10 Перл Терапьютикс, Инк. Compositions for respiratory delivery of active substances and methods and systems connected therewith
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
CA2907566A1 (en) 2013-04-01 2014-10-09 Pulmatrix, Inc. Tiotropium dry powders

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PT77471B (en) * 1982-10-08 1986-08-19 Glaxo Group Ltd Devices for administering medicaments to patients
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US6536427B2 (en) * 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
US5785049A (en) * 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US5826633A (en) * 1996-04-26 1998-10-27 Inhale Therapeutic Systems Powder filling systems, apparatus and methods
PL200941B1 (en) * 1998-11-13 2009-02-27 Jagotec Ag Dry powder for inhalation
MXPA01012533A (en) * 1999-06-05 2003-10-14 Innovata Biomed Ltd Delivery system.
CZ20021198A3 (en) * 1999-10-11 2002-09-11 Ml Laboratories Plc Device for administering a medicament having surface treatment resistant to moisture
SE517806C2 (en) * 1999-11-11 2002-07-16 Microdrug Ag Dosing Device for inhalers
SE9904706D0 (en) * 1999-12-21 1999-12-21 Astra Ab An inhalation device
GB0009468D0 (en) * 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formulations for use in inhaler devices
PE12272001A1 (en) * 2000-04-17 2002-01-07 Chiesi Farma Spa Pharmaceutical formulations for DPIs in the form of hard agglomerates
GB0015043D0 (en) * 2000-06-21 2000-08-09 Glaxo Group Ltd Medicament dispenser
US20020017295A1 (en) * 2000-07-07 2002-02-14 Weers Jeffry G. Phospholipid-based powders for inhalation
SE517225C2 (en) * 2000-09-21 2002-05-14 Microdrug Ag Optimization of a static-metered dry powder inhaler
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US7258118B2 (en) * 2002-01-24 2007-08-21 Sofotec Gmbh & Co, Kg Pharmaceutical powder cartridge, and inhaler equipped with same
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JP2005525393A (en) * 2002-04-09 2005-08-25 ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト Inhalation kit containing the inhalable powder of tiotropium
US20030235538A1 (en) * 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
SE524957C2 (en) * 2002-04-12 2004-11-02 Microdrug Ag Method for sharing and distribution of air in the dry powder
SE525027C2 (en) * 2002-04-12 2004-11-16 Microdrug Ag Device forming a powder Air-razor
SE524990C2 (en) * 2002-04-12 2004-11-09 Microdrug Ag Preparation of therapeutic dry powder and the method of division and dispersal into air of medication powder
GB0225621D0 (en) * 2002-11-02 2002-12-11 Glaxo Group Ltd Medicament carrier
SE0303570A (en) * 2003-12-03 2005-06-04 Microdrug Ag Moisture-sensitive medical product
SE0303269A (en) * 2003-12-03 2005-06-04 Microdrug Ag medical product
SE0303270A (en) * 2003-12-03 2005-06-04 Microdrug Ag Method for administration of tiotropium
SE0303569A (en) * 2003-12-03 2005-06-04 Microdrug Ag DPI delivery of moisture sensitive medicament
SE0303571D0 (en) * 2003-12-03 2003-12-22 Microdrug Ag Medical product for moisture-sensitive medicaments
SE0402345L (en) * 2004-09-24 2006-03-25 Mederio Ag measured drug dose

Also Published As

Publication number Publication date
AU2004294887A1 (en) 2005-06-16
US20070110678A1 (en) 2007-05-17
AU2004294887B2 (en) 2009-12-24
ZA200604254B (en) 2008-05-28
SI1991202T1 (en) 2010-03-31
ES2333725T3 (en) 2010-02-26
AT448776T (en) 2009-12-15
SE0303270D0 (en) 2003-12-03
EP1991202B1 (en) 2009-11-18
WO2005053645A1 (en) 2005-06-16
CA2547660A1 (en) 2005-06-16
DE602004024261D1 (en) 2009-12-31
DK1991202T3 (en) 2010-04-06
CY1110625T1 (en) 2015-04-29
PT1991202E (en) 2009-12-10
US20050121026A1 (en) 2005-06-09
EP1991202A1 (en) 2008-11-19

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