RU96102079A - Magnesium Omeprazole Salt - Google Patents
Magnesium Omeprazole SaltInfo
- Publication number
- RU96102079A RU96102079A RU96102079/04A RU96102079A RU96102079A RU 96102079 A RU96102079 A RU 96102079A RU 96102079/04 A RU96102079/04 A RU 96102079/04A RU 96102079 A RU96102079 A RU 96102079A RU 96102079 A RU96102079 A RU 96102079A
- Authority
- RU
- Russia
- Prior art keywords
- salt
- omeprazole
- paragraphs
- magnesium
- salt according
- Prior art date
Links
- 229910052749 magnesium Inorganic materials 0.000 title claims 4
- 239000011777 magnesium Substances 0.000 title claims 4
- -1 Magnesium Omeprazole Salt Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 claims 17
- 239000011780 sodium chloride Substances 0.000 claims 17
- SUBDBMMJDZJVOS-UHFFFAOYSA-N Esomeprazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 claims 13
- 229960000381 omeprazole Drugs 0.000 claims 10
- 159000000003 magnesium salts Chemical class 0.000 claims 9
- 230000028327 secretion Effects 0.000 claims 5
- 239000002904 solvent Substances 0.000 claims 4
- 241000124008 Mammalia Species 0.000 claims 3
- 210000002784 Stomach Anatomy 0.000 claims 3
- 239000002253 acid Substances 0.000 claims 3
- 238000002425 crystallisation Methods 0.000 claims 3
- 230000005712 crystallization Effects 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- FYYHWMGAXLPEAU-UHFFFAOYSA-N magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 3
- 210000004211 Gastric Acid Anatomy 0.000 claims 2
- 210000001156 Gastric Mucosa Anatomy 0.000 claims 2
- 238000004817 gas chromatography Methods 0.000 claims 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N methanol Chemical group OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 238000003109 Karl Fischer titration Methods 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 238000005119 centrifugation Methods 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drugs Drugs 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 238000001704 evaporation Methods 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000002798 polar solvent Substances 0.000 claims 1
- 230000001681 protective Effects 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 239000011541 reaction mixture Substances 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
Claims (29)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE19939302396A SE9302396D0 (en) | 1993-07-09 | 1993-07-09 | A NOVEL COMPOUND FORM |
SE9302396-8 | 1993-07-09 | ||
PCT/SE1994/000680 WO1995001977A1 (en) | 1993-07-09 | 1994-07-08 | Magnesium omeprazole |
Publications (2)
Publication Number | Publication Date |
---|---|
RU96102079A true RU96102079A (en) | 1998-05-20 |
RU2139868C1 RU2139868C1 (en) | 1999-10-20 |
Family
ID=20390588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU96102079A RU2139868C1 (en) | 1993-07-09 | 1994-07-08 | Omeprazole magnesium salt, method of its preparing, pharmaceutical composition, method of treatment |
Country Status (42)
Country | Link |
---|---|
US (1) | US5900424A (en) |
EP (2) | EP1164132A3 (en) |
JP (2) | JP3635432B2 (en) |
KR (1) | KR100353783B1 (en) |
CN (1) | CN1064680C (en) |
AT (1) | ATE212628T1 (en) |
AU (1) | AU679766B2 (en) |
BR (1) | BR9406940A (en) |
CA (1) | CA2166794C (en) |
CZ (1) | CZ288933B6 (en) |
DE (2) | DE69429774T2 (en) |
DK (1) | DK0707580T3 (en) |
DZ (1) | DZ1792A1 (en) |
EE (1) | EE03127B1 (en) |
EG (1) | EG21437A (en) |
ES (1) | ES2100136T3 (en) |
FI (1) | FI114154B (en) |
GR (1) | GR970300015T1 (en) |
HK (1) | HK1008329A1 (en) |
HR (1) | HRP940385B1 (en) |
HU (1) | HU226861B1 (en) |
IL (1) | IL110190A (en) |
IS (1) | IS2075B (en) |
MA (1) | MA23257A1 (en) |
MX (1) | MX9405217A (en) |
MY (1) | MY113274A (en) |
NO (1) | NO308702B1 (en) |
NZ (1) | NZ268693A (en) |
PL (1) | PL175999B1 (en) |
PT (1) | PT707580E (en) |
RU (1) | RU2139868C1 (en) |
SA (1) | SA94150058B1 (en) |
SE (1) | SE9302396D0 (en) |
SG (1) | SG52464A1 (en) |
SI (1) | SI0707580T1 (en) |
SK (1) | SK281230B6 (en) |
TN (1) | TNSN94079A1 (en) |
TW (1) | TW504509B (en) |
UA (1) | UA43343C2 (en) |
WO (1) | WO1995001977A1 (en) |
YU (1) | YU49193B (en) |
ZA (1) | ZA944933B (en) |
Families Citing this family (92)
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SE9301830D0 (en) * | 1993-05-28 | 1993-05-28 | Ab Astra | NEW COMPOUNDS |
US6875872B1 (en) * | 1993-05-28 | 2005-04-05 | Astrazeneca | Compounds |
SE9302395D0 (en) * | 1993-07-09 | 1993-07-09 | Ab Astra | NEW PHARMACEUTICAL FORMULATION |
SE9302396D0 (en) * | 1993-07-09 | 1993-07-09 | Ab Astra | A NOVEL COMPOUND FORM |
SK283626B6 (en) | 1994-07-08 | 2003-10-07 | Astrazeneca Ab | Multiple unit tableted dosage, process for its production and use |
WO1996001622A1 (en) * | 1994-07-08 | 1996-01-25 | Astra Aktiebolag | New oral pharmaceutical formulation containing magnesium salt of omeprazole |
SE9500478D0 (en) * | 1995-02-09 | 1995-02-09 | Astra Ab | New pharmaceutical formulation and process |
US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
US6645988B2 (en) | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US6699885B2 (en) * | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
SE9600070D0 (en) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
SE508669C2 (en) * | 1996-04-26 | 1998-10-26 | Astra Ab | New procedure |
US6623759B2 (en) | 1996-06-28 | 2003-09-23 | Astrazeneca Ab | Stable drug form for oral administration with benzimidazole derivatives as active ingredient and process for the preparation thereof |
TW385306B (en) * | 1996-11-14 | 2000-03-21 | Takeda Chemical Industries Ltd | Method for producing crystals of benzimidazole derivatives |
SE510666C2 (en) * | 1996-12-20 | 1999-06-14 | Astra Ab | New Crystal Modifications |
SE9702000D0 (en) * | 1997-05-28 | 1997-05-28 | Astra Ab | New pharmaceutical formulation |
US6747155B2 (en) | 1997-05-30 | 2004-06-08 | Astrazeneca Ab | Process |
SE510650C2 (en) * | 1997-05-30 | 1999-06-14 | Astra Ab | New association |
US6096340A (en) | 1997-11-14 | 2000-08-01 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
US6174548B1 (en) | 1998-08-28 | 2001-01-16 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
SE9704870D0 (en) | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulation I |
FR2774288B1 (en) * | 1998-01-30 | 2001-09-07 | Ethypharm Sa | GASTROPROTEGED OMEPRAZOLE MICROGRANULES, PROCESS FOR OBTAINING AND PHARMACEUTICAL PREPARATIONS |
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IL142703A (en) * | 1998-11-10 | 2006-04-10 | Astrazeneca Ab | Crystalline form of omeprazole |
UA72748C2 (en) | 1998-11-10 | 2005-04-15 | Astrazeneca Ab | A novel crystalline form of omeprazole |
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US8911787B2 (en) | 2008-02-26 | 2014-12-16 | Ranbaxy Laboratories Limited | Stable oral benzimidazole compositions and process of preparation thereof |
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WO2013101897A2 (en) | 2011-12-28 | 2013-07-04 | Pozen Inc. | Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid |
CN102993184A (en) * | 2013-01-08 | 2013-03-27 | 湖南方盛制药股份有限公司 | Esomeprazole and preparation method of magnesium trihydrate of esomeprazole |
WO2016174664A1 (en) | 2015-04-29 | 2016-11-03 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
WO2017145146A1 (en) | 2016-02-25 | 2017-08-31 | Dexcel Pharma Technologies Ltd. | Compositions comprising proton pump inhibitors |
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WO2024075017A1 (en) | 2022-10-04 | 2024-04-11 | Zabirnyk Arsenii | Inhibition of aortic valve calcification |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE7804231L (en) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Gastric acid secretion |
SE8301182D0 (en) * | 1983-03-04 | 1983-03-04 | Haessle Ab | NOVEL COMPOUNDS |
GB2189698A (en) * | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated omeprazole tablets |
DE4035455A1 (en) * | 1990-11-08 | 1992-05-14 | Byk Gulden Lomberg Chem Fab | ENANTIOMER SEPARATION |
SE9302396D0 (en) * | 1993-07-09 | 1993-07-09 | Ab Astra | A NOVEL COMPOUND FORM |
-
1993
- 1993-07-09 SE SE19939302396A patent/SE9302396D0/en unknown
-
1994
- 1994-06-23 TW TW083105710A patent/TW504509B/en not_active IP Right Cessation
- 1994-07-01 HR HR940385A patent/HRP940385B1/en not_active IP Right Cessation
- 1994-07-01 IL IL11019094A patent/IL110190A/en not_active IP Right Cessation
- 1994-07-04 SA SA94150058A patent/SA94150058B1/en unknown
- 1994-07-05 IS IS4186A patent/IS2075B/en unknown
- 1994-07-07 ZA ZA944933A patent/ZA944933B/en unknown
- 1994-07-07 EG EG40794A patent/EG21437A/en active
- 1994-07-07 MY MYPI94001774A patent/MY113274A/en unknown
- 1994-07-07 MA MA23567A patent/MA23257A1/en unknown
- 1994-07-08 EP EP01117362A patent/EP1164132A3/en not_active Withdrawn
- 1994-07-08 CZ CZ199669A patent/CZ288933B6/en not_active IP Right Cessation
- 1994-07-08 CA CA002166794A patent/CA2166794C/en not_active Expired - Lifetime
- 1994-07-08 CN CN94192733A patent/CN1064680C/en not_active Expired - Lifetime
- 1994-07-08 WO PCT/SE1994/000680 patent/WO1995001977A1/en active IP Right Grant
- 1994-07-08 EP EP94921154A patent/EP0707580B1/en not_active Expired - Lifetime
- 1994-07-08 RU RU96102079A patent/RU2139868C1/en active
- 1994-07-08 US US08/313,342 patent/US5900424A/en not_active Expired - Lifetime
- 1994-07-08 HU HU9503873A patent/HU226861B1/en unknown
- 1994-07-08 AU AU71981/94A patent/AU679766B2/en not_active Expired
- 1994-07-08 PT PT94921154T patent/PT707580E/en unknown
- 1994-07-08 MX MX9405217A patent/MX9405217A/en unknown
- 1994-07-08 DE DE69429774T patent/DE69429774T2/en not_active Expired - Lifetime
- 1994-07-08 UA UA96010059A patent/UA43343C2/en unknown
- 1994-07-08 TN TNTNSN94079A patent/TNSN94079A1/en unknown
- 1994-07-08 AT AT94921154T patent/ATE212628T1/en active
- 1994-07-08 SG SG1996004887A patent/SG52464A1/en unknown
- 1994-07-08 SI SI9430414T patent/SI0707580T1/en unknown
- 1994-07-08 SK SK22-96A patent/SK281230B6/en not_active IP Right Cessation
- 1994-07-08 PL PL94312440A patent/PL175999B1/en unknown
- 1994-07-08 NZ NZ268693A patent/NZ268693A/en not_active IP Right Cessation
- 1994-07-08 KR KR1019960700051A patent/KR100353783B1/en not_active IP Right Cessation
- 1994-07-08 YU YU43694A patent/YU49193B/en unknown
- 1994-07-08 BR BR9406940A patent/BR9406940A/en not_active Application Discontinuation
- 1994-07-08 DK DK94921154T patent/DK0707580T3/en active
- 1994-07-08 JP JP50400595A patent/JP3635432B2/en not_active Expired - Lifetime
- 1994-07-08 ES ES94921154T patent/ES2100136T3/en not_active Expired - Lifetime
- 1994-07-08 DE DE0707580T patent/DE707580T1/en active Pending
- 1994-11-17 EE EE9400405A patent/EE03127B1/en unknown
- 1994-11-27 DZ DZ940071A patent/DZ1792A1/en active
-
1996
- 1996-01-05 NO NO960068A patent/NO308702B1/en not_active IP Right Cessation
- 1996-01-09 FI FI960101A patent/FI114154B/en not_active IP Right Cessation
-
1997
- 1997-05-30 GR GR970300015T patent/GR970300015T1/en unknown
-
1998
- 1998-07-17 HK HK98109227A patent/HK1008329A1/en not_active IP Right Cessation
-
2001
- 2001-09-26 JP JP2001293480A patent/JP3878826B2/en not_active Expired - Lifetime
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