RU93052149A - Аналоги витамины d*003 - Google Patents

Аналоги витамины d*003

Info

Publication number
RU93052149A
RU93052149A RU93052149/04A RU93052149A RU93052149A RU 93052149 A RU93052149 A RU 93052149A RU 93052149/04 A RU93052149/04 A RU 93052149/04A RU 93052149 A RU93052149 A RU 93052149A RU 93052149 A RU93052149 A RU 93052149A
Authority
RU
Russia
Prior art keywords
analogues
vitamin
diseases
compounds
groups
Prior art date
Application number
RU93052149/04A
Other languages
English (en)
Other versions
RU2126385C1 (ru
Inventor
И.Доран Томас
Артур Маклейн Джон
Окабе Масами
СКАЛОНЕ Микельанджело
Радое Ускокович Милан
Original Assignee
Ф.Хоффманн - Ля Рош АГ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ф.Хоффманн - Ля Рош АГ filed Critical Ф.Хоффманн - Ля Рош АГ
Publication of RU93052149A publication Critical patent/RU93052149A/ru
Application granted granted Critical
Publication of RU2126385C1 publication Critical patent/RU2126385C1/ru

Links

Claims (1)

  1. Предложены соединения формулы
    Figure 00000001

    в которой R1 и R2 представляют собой водород или группу ацила, при условии, что лишь одна из групп R1 или R2 представляет собой водород, которые используются для лечения от гиперпролиферативных заболеваний кожи и от заболеваний сальных желез.
RU93052149A 1992-11-20 1993-11-15 Аналоги витамина d3, способ их получения, фармацевтическая композиция RU2126385C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97913392A 1992-11-20 1992-11-20
US979.133 1992-11-20
US979133 1992-11-20

Publications (2)

Publication Number Publication Date
RU93052149A true RU93052149A (ru) 1996-12-27
RU2126385C1 RU2126385C1 (ru) 1999-02-20

Family

ID=25526724

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93052149A RU2126385C1 (ru) 1992-11-20 1993-11-15 Аналоги витамина d3, способ их получения, фармацевтическая композиция

Country Status (25)

Country Link
US (3) US5342833A (ru)
EP (1) EP0599114B1 (ru)
JP (2) JP2502931B2 (ru)
KR (1) KR940011443A (ru)
CN (1) CN1051762C (ru)
AT (1) ATE147728T1 (ru)
AU (1) AU669222B2 (ru)
BR (1) BR9304780A (ru)
CA (1) CA2108848A1 (ru)
CZ (1) CZ284415B6 (ru)
DE (1) DE69307478T2 (ru)
DK (1) DK0599114T3 (ru)
ES (1) ES2097423T3 (ru)
FI (1) FI935092A (ru)
GR (1) GR3022691T3 (ru)
HU (1) HU213609B (ru)
IL (1) IL107614A (ru)
NO (1) NO304022B1 (ru)
NZ (1) NZ250194A (ru)
PH (1) PH30991A (ru)
PL (1) PL176017B1 (ru)
RU (1) RU2126385C1 (ru)
TW (1) TW267161B (ru)
UY (1) UY23678A1 (ru)
ZA (1) ZA938478B (ru)

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ZA95906B (en) * 1994-02-07 1996-08-06 Res Developments Foundation Non-viral vector
AU7364896A (en) * 1995-10-10 1997-04-30 Marilyn Strube Treatment of pruritus with vitamin d and analogs thereof
TW403735B (en) * 1995-11-22 2000-09-01 Hoffmann La Roche 25-hydroxy-16-ene-26, 27-bishomo-cholecalciferol
US5691328A (en) * 1996-02-02 1997-11-25 Clarion Pharmaceuticals Inc. Phosphoethanolamine conjugates of vitamin D compounds
NO971934L (no) * 1996-05-23 1997-11-24 Hoffmann La Roche Flourinerte vitamin D3 -analoger
US5939408A (en) 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
EP0884308B1 (en) * 1997-05-02 2003-04-16 Duphar International Research B.V A method of preparing 16-dehydro vitamin D compounds
US8404667B2 (en) * 2006-12-29 2013-03-26 Wisconsin Alumni Research Foundation Compounds, compositions, kits and methods of use to orally and topically treat acne and other skin conditions by 19-Nor vitamin D analog
EP1812011A1 (en) 2004-11-12 2007-08-01 Bioxell S.p.a. Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
WO2015115796A1 (ko) 2014-01-29 2015-08-06 주식회사 휴메딕스 페길레이션된 7-디하이드로콜레스테롤 유도체
KR101702076B1 (ko) 2015-02-25 2017-02-02 주식회사 휴메딕스 지방산 컨쥬게이션된 7-데하이드로콜레스테롤 유도체

Family Cites Families (22)

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US3970676A (en) * 1974-10-29 1976-07-20 The Upjohn Company Novel process and intermediate compounds used is preparation of -Δ5,7- steroid dienes
US4116985A (en) * 1976-07-26 1978-09-26 The Upjohn Company Novel method for preparing cholesta-5,7-diene 3β,25-diol and derivatives thereof
US4360471A (en) * 1981-12-11 1982-11-23 Wisconsin Alumni Research Foundation 23-Dehydro-25-hydroxyvitamin D3
US4456553A (en) * 1982-05-07 1984-06-26 Teijin Limited Vitamin D3 derivatives, process for preparation thereof, and antigens comprising said derivatives to be used for preparation of antibodies for immunochemical assay and antibodies prepared therefrom
US4448721A (en) * 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same
JPS63264452A (ja) * 1986-10-20 1988-11-01 Sumitomo Pharmaceut Co Ltd フッ素化ビタミンｄ↓３誘導体
DE3881665T2 (de) * 1987-03-30 1993-10-07 Kuraray Co Pregnanabkömmlinge und verfahren zur herstellung.
US5145846A (en) * 1988-01-20 1992-09-08 Hoffmann-La Roche Inc. Vitamin D3 analogs
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
US5087619A (en) * 1988-01-20 1992-02-11 Hoffman-La Roche Inc. Vitamin D3 analogs
ZA8923B (en) * 1988-01-20 1989-09-27 Hoffmann La Roche 16-dehydro-vitamin d3-derivatives
ATE124416T1 (de) * 1988-07-05 1995-07-15 Kuraray Co Steroid-verbindungen.
US4973584A (en) * 1989-03-09 1990-11-27 Deluca Hector F Novel 1α-hydroxyvitamin D2 epimer and derivatives
NZ232734A (en) * 1989-03-09 1991-11-26 Wisconsin Alumni Res Found 19-nor vitamin d derivatives and pharmaceutical compositions
CA1333616C (en) * 1989-03-09 1994-12-20 Hector F. Deluca 19-nor-vitamin d compounds
DK0398217T3 (da) * 1989-05-18 1994-02-14 Hoffmann La Roche Dehydrocholecalciferolderivater
AU6441890A (en) * 1989-09-11 1991-04-08 Wisconsin Alumni Research Foundation Novel use of vitamin d compounds to inhibit replication of the aids virus
JPH05501718A (ja) * 1990-02-06 1993-04-02 シェーリング　アクチェンゲゼルシャフト 側鎖同族体ビタミン―ｄ―誘導体、その製造法ならびに該誘導体を含有する、過増殖を示す疾病を治療するための製薬学的調製剤
DE4101953A1 (de) * 1991-01-19 1992-07-23 Schering Ag 23-oxa-derivate in der vitamin-d-reihe, verfahren zu ihrer herstellung diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel
DE4105503A1 (de) * 1991-02-19 1992-08-20 Jenapharm Gmbh Ausgangsverbindungen zur herstellung von calcitriol sowie dessen abkoemmlingen, verfahren zur herstellung dieser ausgangsverbindungen sowie zwischenprodukte fuer dieses verfahren
US5206230A (en) * 1991-06-05 1993-04-27 Daikin Industries, Ltd. Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
DK0521550T3 (da) * 1991-07-05 1996-11-04 Duphar Int Res Vitamin D forbindelse, fremgangsmåde til fremstilling af denne forbindelse og mellemprodukt derfor

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