RU2743409C2 - Способы лечения состояний, связанных с masp-2 зависимой активацией комплемента - Google Patents
Способы лечения состояний, связанных с masp-2 зависимой активацией комплемента Download PDFInfo
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- RU2743409C2 RU2743409C2 RU2018125514A RU2018125514A RU2743409C2 RU 2743409 C2 RU2743409 C2 RU 2743409C2 RU 2018125514 A RU2018125514 A RU 2018125514A RU 2018125514 A RU2018125514 A RU 2018125514A RU 2743409 C2 RU2743409 C2 RU 2743409C2
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- A—HUMAN NECESSITIES
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
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- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
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- Psychiatry (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161473698P | 2011-04-08 | 2011-04-08 | |
| US61/473,698 | 2011-04-08 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2013149792A Division RU2662563C2 (ru) | 2011-04-08 | 2012-04-06 | Способы лечения состояний, связанных с masp-2 зависимой активацией комплемента |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2021103424A Division RU2852982C2 (ru) | 2011-04-08 | 2021-02-12 | Способы лечения состояний, связанных с masp-2-зависимой активацией комплемента |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2018125514A RU2018125514A (ru) | 2019-03-12 |
| RU2018125514A3 RU2018125514A3 (https=) | 2019-10-30 |
| RU2743409C2 true RU2743409C2 (ru) | 2021-02-18 |
Family
ID=46966283
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2018125514A RU2743409C2 (ru) | 2011-04-08 | 2012-04-06 | Способы лечения состояний, связанных с masp-2 зависимой активацией комплемента |
| RU2013149792A RU2662563C2 (ru) | 2011-04-08 | 2012-04-06 | Способы лечения состояний, связанных с masp-2 зависимой активацией комплемента |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2013149792A RU2662563C2 (ru) | 2011-04-08 | 2012-04-06 | Способы лечения состояний, связанных с masp-2 зависимой активацией комплемента |
Country Status (17)
| Country | Link |
|---|---|
| US (6) | US8951522B2 (https=) |
| EP (3) | EP3964233A1 (https=) |
| JP (4) | JP5937197B2 (https=) |
| KR (6) | KR101870915B1 (https=) |
| CN (3) | CN110075294A (https=) |
| AU (1) | AU2012239889B2 (https=) |
| BR (1) | BR112013025917A2 (https=) |
| CA (4) | CA3076975C (https=) |
| CL (1) | CL2013002874A1 (https=) |
| DK (2) | DK2694108T3 (https=) |
| ES (2) | ES2683307T3 (https=) |
| IL (3) | IL228758B (https=) |
| MX (3) | MX381987B (https=) |
| NZ (5) | NZ731596A (https=) |
| PL (1) | PL3287142T3 (https=) |
| RU (2) | RU2743409C2 (https=) |
| WO (1) | WO2012139081A2 (https=) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0688182B2 (ja) | 1986-09-08 | 1994-11-09 | バブコツク日立株式会社 | スタツド着脱装置 |
| US20090010920A1 (en) | 2003-03-03 | 2009-01-08 | Xencor, Inc. | Fc Variants Having Decreased Affinity for FcyRIIb |
| KR101870915B1 (ko) | 2011-04-08 | 2018-06-25 | 유니버시티 오브 레스터 | Masp-2 의존적 보체 활성화와 관련된 질병을 치료하는 방법 |
| US9644035B2 (en) | 2011-04-08 | 2017-05-09 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
| PE20150159A1 (es) * | 2011-12-21 | 2015-02-08 | Novartis Ag | Composiciones y metodos para anticuerpos que actuan sobre el factor p |
| WO2013180834A2 (en) * | 2012-04-06 | 2013-12-05 | Omeros Corporation | Compositions and methods of inhibting masp-1 and/or masp-3 for the treatment of paroxysmal nocturnal hemoglobinuria |
| KR102339315B1 (ko) * | 2012-06-18 | 2021-12-15 | 오메로스 코포레이션 | 다양한 질환 및 장애의 치료를 위해 masp-1 및/또는 masp-2 및/또는 masp-3를 억제하는 조성물 및 방법 |
| CN104870475B (zh) | 2012-10-25 | 2019-11-08 | 美国比奥维拉迪维股份有限公司 | 抗补体C1s抗体和其用途 |
| DK2914291T3 (da) | 2012-11-02 | 2022-05-16 | Bioverativ Usa Inc | Anti-komplement-c1s-antistoffer og anvendelser deraf |
| US20140363433A1 (en) | 2013-03-15 | 2014-12-11 | Omeros Corporation | Methods of Generating Bioactive Peptide-bearing Antibodies and Compositions Comprising the Same |
| ES2964340T3 (es) | 2013-03-15 | 2024-04-05 | Omeros Corp | Métodos para generar anticuerpos portadores de péptidos bioactivos y composiciones que comprenden los mismos |
| SMT202000659T1 (it) * | 2013-10-17 | 2021-01-05 | Omeros Corp | Metodi per il trattamento delle condizioni associate all'attivazione del complemento dipendente dalla masp-2 |
| WO2015070041A1 (en) * | 2013-11-08 | 2015-05-14 | Icahn School Of Medicine At Mount Sinai | Methods for monitoring kidney dysfunction |
| AU2015274482B2 (en) | 2014-06-12 | 2018-11-08 | Ucb Holdings, Inc. | Modulation of complement activity |
| EP3250230B9 (en) | 2015-01-28 | 2022-02-23 | RA Pharmaceuticals, Inc. | Modulators of complement activity |
| WO2016164358A1 (en) | 2015-04-06 | 2016-10-13 | True North Therapeutics, Inc. | Humanized anti-c1s antibodies and methods of use thereof |
| CN108472347B (zh) | 2015-11-09 | 2023-09-05 | 奥默罗斯公司 | 用于治疗与masp-2依赖性补体活化相关的病况的方法 |
| ES2941640T3 (es) | 2015-12-16 | 2023-05-24 | Ra Pharmaceuticals Inc | Moduladores de la actividad del complemento |
| MX2018007392A (es) * | 2015-12-23 | 2018-08-15 | Greenovation Biotech Gmbh | Polipeptidos para inhibir la activacion del complemento. |
| US10736960B2 (en) * | 2016-01-05 | 2020-08-11 | Omeros Corporation | Methods for inhibiting fibrosis in a subject in need thereof |
| WO2017173290A1 (en) | 2016-03-31 | 2017-10-05 | Omeros Corporation | Methods for inhibiting angiogenesis in a subject in need thereof |
| UY37376A (es) * | 2016-08-26 | 2018-03-23 | Amgen Inc | Construcciones de arni para inhibir expresión de asgr1 y métodos para su uso |
| JOP20170170B1 (ar) * | 2016-08-31 | 2022-09-15 | Omeros Corp | صيغ لجسم مضاد تثبيطية لـ masp-2 بتركيز عالي ولزوجة منخفضة وأطقم، وطرق |
| HUE073475T2 (hu) | 2016-10-12 | 2026-01-28 | Bioverativ Usa Inc | C1s elleni antitestek és alkalmazási eljárásaik |
| IL265981B2 (en) * | 2016-10-13 | 2025-05-01 | Univ Leicester | Methods for reducing proteinuria in a human subject suffering from immunoglobulin a nephropathy |
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2016
- 2016-05-11 JP JP2016095034A patent/JP6239030B2/ja active Active
- 2016-12-07 US US15/371,726 patent/US10202465B2/en active Active
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2017
- 2017-10-31 JP JP2017209894A patent/JP6584476B2/ja active Active
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2018
- 2018-12-17 US US16/222,188 patent/US20190292272A1/en not_active Abandoned
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2019
- 2019-01-09 IL IL264172A patent/IL264172B/en unknown
- 2019-09-03 JP JP2019160040A patent/JP6893539B2/ja active Active
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2020
- 2020-04-23 IL IL274206A patent/IL274206A/en unknown
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2021
- 2021-09-09 US US17/470,386 patent/US20220089781A1/en not_active Abandoned
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2025
- 2025-05-21 US US19/214,532 patent/US20260062498A1/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004032973A2 (en) * | 2002-10-09 | 2004-04-22 | Aurelio Maggio | Use of sns insulator of sea urchin for the gene therapy of erythroid cell diseases |
| US7919094B2 (en) * | 2004-06-10 | 2011-04-05 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
| RU2008143559A (ru) * | 2006-04-03 | 2010-05-10 | ОМЕРОС КОРПОРЕЙШЕН, Соединенные Штаты Америки (US) | Способ лечения заболеваний, связанных с masp-2-зависимой активацией комплемента (варианты) |
Non-Patent Citations (1)
| Title |
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| PARKER C. Complement and Hematology//The Hematologist, January-February 2011, Volume 8, Issue 1 он лайн, найдено 18.10.2019, найдено в Интернет (https://www.hematology.org/Thehematologist/Mini-Review/6324.aspx). * |
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