RU2527318C2 - Device for infrared exposure on collagen layer of human skin with visualising of process - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: invention refers to medicine and concerns a device for the infrared exposure on the human skin. The device is presented in the form of a magnetic resonance tomographic scanner and comprises a receive/transmit channel, a three-dimensional localisation unit, a microprocessor controller and a display. The device is also provided with a local exposure unit presented in the form of a manipulator with an IR laser, a lens and a marker for laser beam binding to a coordinate system of the analysed area.

EFFECT: higher accuracy and intensity of the local exposure, as well as providing object tissue change tracking.

3 cl, 1 dwg

Description

The technical solution relates to the field of medicine and biology and is intended for scanning the skin surface of a biological object using nuclear magnetic and quadrupole resonances (NMR and NQR) and exposure of its collagen layer to infrared (IR) radiation to visualize the process.

The device can be used, for example, to scan the subcutaneous layer of a biological object and the impact on its collagen layer. It can also be used to destroy intrauterine formations in gynecology, formations in the intestine, etc.

Close to the claimed solution is the patent US 5533998 (DE4430720 A1) [1]. The solution uses ultrasound imaging, but it requires a certain medium (liquid) for the optimal passage of ultrasound into the studied area, which greatly complicates the method and device. There is no possibility of control over changes in the physical parameters and structure of the tissue of the object.

Closest to the proposed solution is "Method and device for scanning and local exposure to the studied area in biological objects" according to the patent of the Russian Federation No. 2353922 IPC G01N 24/00 [2]. The scanning device, which is a magnetic resonance imager (MRI), contains a transceiver channel for generating radio frequency pulses, a spatial localization unit for isolating and storing individual parameters and a display.

The disadvantages of this device include the fact that the local resonant effect on the studied area is relatively weak, not allowing structurally changing the selected area.

The purpose of creating a new technical solution is to provide the possibility of local impact on the problem area of the object until destruction, as well as the ability to track ongoing changes in the tissue of the object.

This goal is achieved by the fact that in the device for scanning and local exposure to electromagnetic skin on human skin, which is a magnetic resonance imager containing a transceiver channel that generates radio frequency pulses and converts resonance signals, a spatial localization unit and a display, an additional local unit exposure, which is made in the form of a manipulator with an IR laser and a lens. The device is also equipped with a marker for linking the laser beam to the coordinate system of the investigated area. In this case, the marker is made in the form of a capsule (ampoule) of a non-magnetic material filled with a liquid containing, for example, fluorine nucleus.

The device, which is a magnetic resonance imager with a local exposure unit, allows, by scanning and acting on a selected area, to simultaneously monitor tissue changes, such as structure and temperature, using NMR and NQR methods.

The introduction of a block of local influence on the region chosen by the operator, made in the form of a manipulator using the energy of infrared radiation, and the lens, allows you to locally affect the selected area of the object by moving the lens, focusing at the desired depth.

The presence of a marker made in the form of a capsule (ampoule) provides the ability to attach the laser beam to the coordinate system of the object by identifying the marker during scanning using a magnetic resonance imager.

The essence of the presented technical solution is illustrated by the drawing, which shows a block diagram of the device.

The inventive device comprises: a transmitting and receiving channel 1, generating radio frequency pulses, the spectrum of which coincides with the NMR spectrum of ¹ N hydrogen nuclei and the NQR spectrum of ¹⁴ N nitrogen nuclei, and converting NMR signals ¹ H and NQR ¹⁴ N, spatial localization unit 2 for separation and storing parameters of the region selected by the operator in the object under study, a microprocessor controller 3 that controls the transceiver channel 1, spatial localization unit 2, and terminal 4 (a display with a keyboard and a mouse-type manipulator). In contrast to the prototype, the claimed device containing the above elements contains a local exposure unit 5 on the region selected by the operator using the radiation energy of an infrared laser.

The device operates as follows. Initially, the object is scanned using nuclear magnetic resonance (magnetic resonance imaging - MRI) [3] and the operator’s area of interest is determined, the converted data array of which is stored in the controller’s memory. Then, a local exposure unit (a manipulator with a laser) is installed on the object. When the manipulator moves, the auto-alignment (binding to the surface coordinates) of the semiconductor laser lens is performed at the maximum amplitude of the signal reflected from the surface of the object, as is done in CD or DVD drives. Then, the lens is adjusted so that the focus is at the desired depth below the surface of the object, and the semiconductor laser is switched on to more powerful radiation to affect the tissue of the object. The operator monitors changes in the tissue of the object, for example, structure, temperature, using MRI. The manipulator is linked to the laboratory coordinate system using a marker in the form of a sphere with a diameter of 0.5-1 mm, containing, for example, hydrogen protons, fluorine nuclei, etc., which is detected by the MRI system during scanning. The marker is in close proximity to the laser beam and the surface of the object.

Information sources

1. United States Patent 5533998. Apparatus and method for Laser Cyclo-Photocoagulation / M. Freese, P. Reimer, T. Lasser; Declared Dec. 12.94; Pub. Jul. 9.96.

2. Pat. 2353922 Russian Federation, IPC G 0l 22/04. Method and device for scanning and local impact on the studied area in biological objects / V.V. Fedotov, Yu.S. Litvinov, Zh.Yu. Nesterova, A.V. Fedotov, IL. Korneva; Federal State Institution of Higher Professional Education Russian State University named after I. Kant. No. 2007126501/28; declared 07/11/07; publ. 04/27/09. - 5 sec.

3. Obtaining NMR images with spatial localization / S.Webba // Physics of visualization of images in medicine. - World, 1991 .-- P.105-231.

Claims (3)

1. A device for scanning and local exposure to electromagnetic radiation on human skin, made in the form of a magnetic resonance imager containing a transceiver channel, a spatial localization unit, a microprocessor controller and a display, characterized in that the device is additionally equipped with a local exposure unit, made in a manipulator with an IR laser and a lens, and also equipped with a marker, for linking the laser beam to the coordinate system of the studied area. 2. The device according to claim 1, characterized in that the marker is made in the form of a capsule (ampoule) of non-magnetic material filled with a substance containing liquid, for example, with fluorine nuclei. 3. The device according to claim 1, characterized in that the lens is mounted to move along the laser beam to focus to the desired depth, for local exposure to a selected area of the object.