RU2457214C2 - Способ хроматографии в режиме слабого распределения - Google Patents

Способ хроматографии в режиме слабого распределения Download PDF

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Publication number
RU2457214C2
RU2457214C2 RU2007132851/10A RU2007132851A RU2457214C2 RU 2457214 C2 RU2457214 C2 RU 2457214C2 RU 2007132851/10 A RU2007132851/10 A RU 2007132851/10A RU 2007132851 A RU2007132851 A RU 2007132851A RU 2457214 C2 RU2457214 C2 RU 2457214C2
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product
medium
concentration
protein
specified
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RU2007132851/10A
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RU2007132851A (ru
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Пол БРАУН (US)
Пол БРАУН
Джон КОФМАН (US)
Джон КОФМАН
Ранганасан ГОДАВАРТИ (US)
Ранганасан ГОДАВАРТИ
Тим ИСКРА (US)
Тим ИСКРА
Брайан Д. КЕЛЛИ (US)
Брайан Д. КЕЛЛИ
Сареш ВАННАМ (US)
Сареш ВАННАМ
Шуджан САН (US)
Шуджан САН
Тьяниг Йиу (US)
Тьяниг Йиу
Джеймс Эдвард БУС (US)
Джеймс Эдвард БУС
Мэри Бэт СВИТЦЕР (US)
Мэри Бэт СВИТЦЕР
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Вайет
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/30—Partition chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B01D15/327—Reversed phase with hydrophobic interaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3828—Ligand exchange chromatography, e.g. complexation, chelation or metal interaction chromatography

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
RU2007132851/10A 2005-03-11 2006-03-10 Способ хроматографии в режиме слабого распределения RU2457214C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66043705P 2005-03-11 2005-03-11
US60/660,437 2005-03-11

Publications (2)

Publication Number Publication Date
RU2007132851A RU2007132851A (ru) 2009-04-20
RU2457214C2 true RU2457214C2 (ru) 2012-07-27

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RU2007132851/10A RU2457214C2 (ru) 2005-03-11 2006-03-10 Способ хроматографии в режиме слабого распределения

Country Status (21)

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US (3) US8067182B2 (https=)
EP (1) EP1869065B1 (https=)
JP (1) JP5199063B2 (https=)
KR (2) KR101660575B1 (https=)
CN (2) CN104610422A (https=)
AU (1) AU2006223180B2 (https=)
BR (1) BRPI0608584B8 (https=)
CA (1) CA2601062C (https=)
CR (1) CR9377A (https=)
DK (1) DK1869065T3 (https=)
ES (1) ES2797480T3 (https=)
HK (1) HK1210476A1 (https=)
HU (1) HUE049797T2 (https=)
IL (1) IL185687A (https=)
MX (1) MX2007011129A (https=)
NO (1) NO20074443L (https=)
PL (1) PL1869065T3 (https=)
PT (1) PT1869065T (https=)
RU (1) RU2457214C2 (https=)
SI (1) SI1869065T1 (https=)
WO (1) WO2006099308A2 (https=)

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HK1210476A1 (en) 2016-04-22
SI1869065T1 (sl) 2020-08-31
WO2006099308A2 (en) 2006-09-21
KR20070121667A (ko) 2007-12-27
MX2007011129A (es) 2007-11-06
PT1869065T (pt) 2020-06-18
DK1869065T3 (da) 2020-06-08
BRPI0608584B1 (pt) 2018-02-06
NO20074443L (no) 2007-09-27
US20070054390A1 (en) 2007-03-08
EP1869065A2 (en) 2007-12-26
KR20130128020A (ko) 2013-11-25
US20070060741A1 (en) 2007-03-15
US9144755B2 (en) 2015-09-29
EP1869065B1 (en) 2020-05-06
AU2006223180A1 (en) 2006-09-21
JP5199063B2 (ja) 2013-05-15
IL185687A0 (en) 2008-01-06
HUE049797T2 (hu) 2020-10-28
ES2797480T3 (es) 2020-12-02
US20120138537A1 (en) 2012-06-07
WO2006099308A3 (en) 2007-10-25
CR9377A (es) 2008-02-21
CA2601062A1 (en) 2006-09-21
KR101660575B1 (ko) 2016-09-27
JP2008533473A (ja) 2008-08-21
IL185687A (en) 2015-05-31
CN104610422A (zh) 2015-05-13
CA2601062C (en) 2016-08-02
BRPI0608584A2 (pt) 2010-01-19
KR101482791B1 (ko) 2015-01-21
PL1869065T3 (pl) 2020-09-21
CN101175765A (zh) 2008-05-07
RU2007132851A (ru) 2009-04-20
BRPI0608584B8 (pt) 2021-05-25
AU2006223180B2 (en) 2011-11-24
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