RU2169532C2 - System and method for picking of materials - Google Patents

System and method for picking of materials Download PDF

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Publication number
RU2169532C2
RU2169532C2 RU98110068/14A RU98110068A RU2169532C2 RU 2169532 C2 RU2169532 C2 RU 2169532C2 RU 98110068/14 A RU98110068/14 A RU 98110068/14A RU 98110068 A RU98110068 A RU 98110068A RU 2169532 C2 RU2169532 C2 RU 2169532C2
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chips
bone
cutting tool
drill
cleaning
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RU98110068/14A
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Russian (ru)
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RU98110068A (en
Inventor
Уильям Кэзи Фокс
Брайен Филлип Брукс
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Биомедикал Энтерпрайзис, Инк.
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Priority to US08/550,297 priority
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/025Pointed or sharp biopsy instruments for taking bone, bone marrow or cartilage samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/16Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans
    • A61B17/1635Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans for grafts, harvesting or transplants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/16Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans
    • A61B17/1637Hollow drills or saws producing a curved cut, e.g. cylindrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00969Surgical instruments, devices or methods, e.g. tourniquets used for transplantation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/03Automatic limiting or abutting means, e.g. for safety
    • A61B2090/033Abutting means, stops, e.g. abutting on tissue or skin
    • A61B2090/034Abutting means, stops, e.g. abutting on tissue or skin abutting on parts of the device itself
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/06Measuring instruments not otherwise provided for
    • A61B2090/063Measuring instruments not otherwise provided for for measuring volume

Abstract

FIELD: device and its employment for picking of chip produced by cutting tools. SUBSTANCE: the chip may be of precious metals, toxic or dangerous materials, or of living tissue, for example, bone tissue. In a particular example of picking of bone tissue this innovation consists in provision of equipment used with a drill in such a manner that the bone tissue is aseptically gathered in an accumulating for subsequent transplantation. In the process of use of the tool the chip of the bone and bone marrow is entrapped in the drill flutes, moves to the hole of the device tip and gathered in the accumulating chamber. The drill flutes may be cleaned of the tissue residues by means of a rotary fixture for cleaning, which rotates together with the drill during drilling or during extraction of the drill from the device. In the given example employment of this device provides for picking of viable bone tissue for treatment of injuries or cracks of bones or for fixation of orthopedic or tooth implant contacting with the bone. EFFECT: modified known processes. 45 cl, 1 ex, 2 tbl, 14 dwg

Description

 The present invention relates to those fields of application in which the collection of chips generated during the operation of the cutting tool is carried out. The equipment and methods of its use in industry and medicine are offered. In particular, the present invention relates to a surgical instrument and method of its use, providing for the collection of skeletal tissue. Moreover, the assembled skeletal tissue can be processed and transplanted, preferably to the donor himself, for autologous transplantation.

BACKGROUND OF THE INVENTION
In the manufacture of machine parts in accordance with the requirements of the US military department, the US Food and Drug Administration and the International Organization for Standardization, the chips generated by mechanical processing are collected and returned to the inventory management service to account for all materials issued workshop area. To account for all materials issued, wastes in the form of shavings, residues of bulk materials and machined parts are weighed to confirm that no unknown materials were used uncontrollably in the workshop area. Waste in the form of chips of high-quality medical or military materials is of high cost and therefore cost-effective in processing for recycling. Another example of chip collection is how jewelers collect and recycle materials that fall in the work area during the machining of precious materials, such as gold and silver.

 Another example of the need for equipment for collecting chips is the surgical selection of bone tissue with or without bone marrow. Selected bone tissue is used to treat damage and bone disease. The goal of therapeutic transplantation of bone and bone marrow products is to induce or stimulate bone growth and repair the damaged area or the surrounding area of the implantation site.

 Autologous bone grafts are the "gold standard" by which all transplant materials are evaluated. The collection of fresh autologous bone graft provides all naturally occurring mitogens and growth factors at physiological concentrations, viable populations of mesenchymal and progenitor cells, and a natural bone matrix. An autologous bone graft has greater bone-forming ability compared to an allogeneic graft (tissue from donors of the same species) or xenograft (tissue from donors of different types). Compared to frozen allogeneic and decalcified allogeneic bone grafts, fresh spongy autologous grafts provide healing in most cases. Autogenic bone grafts rule out potential immune and infectious complications associated with the use of allogeneic grafts.

 When trying to reduce the incidence associated with the selection of spongy bone tissue, minimally invasive surgical methods were used, including the use of cylindrical osteotomes to select several bone plugs through one initial cortical entrance. This method takes a lot of time, and the resulting volume of bone tissue is limited. Trepans for bone biopsy have the advantage that they do not disturb the attachment of muscles or ligaments, but in this case, this method limits the volume and shape of the tissue being taken, and collecting the selected material is a tedious procedure.

 Other methods used square or rectangular bone windows that contribute to the extensive incidence of the donor site. Corner lesions created by the formation of normal bone windows weaken the bone structure, since cracks can propagate from the corners of such lesions.

 Devices and systems for cutting bones and suctioning bone marrow tissue have been described previously. Inventions by Bonutti (US Pat. Nos. 5,269,785 and 5,403,317) and Thimsen et al. (US patents 4,649,919 and 4,844,064) relate to orthoscopic tissue removal. The inventions of Johnson (US Pat. No. 5,443,468) and Leuenberger (US Pat. No. 4,111,208) relate to drills and motor attachments for drills. The inventions of the authors Abtopckomy (SU 1644923 A1), Zelenov (SU 1066578) and Michaelson (US patent 5451227 and application WO 9505123) relate to a device for cutting bone tissue. Chin's invention (US Pat. No. 5,385,570) relates to a surgical cutting tool with a recess for collecting material particles. Bone marrow transplant selection methods and devices have been described by Wemer (US Pat. No. 5,407,425), Gillis (US Pat. No. 5,199,942) and Altshuler (US Pat. Nos. 4,486,188 and 4,481,946). Also known is a drill having a vertex with first and second sides, which is used in surgical operations on bones and allows you to remove the resulting chips (copyright certificate of the USSR N 1465033).

 Grant's invention (US Pat. No. 3,466,693) relates to active cleaning of a drill pipe for use in oil fields, and Dillard's invention (US Pat. No. 4,991,452) relates to a sampler for hazardous solid materials.

 Existing chip collection tools do not take into account, for example, the need to specialize the design for a particular application, the need to simply determine the amount of material collected, the need to efficiently move the material to the second site, or the need to create aseptic conditions or a low oxygen environment. In particular, the use of existing equipment for the selection of skeletal tissues and methods of transplantation faces significant problems associated with the characteristics of the material and the methods used for the selection of bone material. The existing methods and the difficulties associated with them are as follows: 1) genetically alien bone and bone matrix often cause an inflammatory reaction and immunogenic rejection; 2) lyophilized bone implants from human donors are slowly vascularized and pose unacceptable risks of postoperative complications, including disease transmission; 3) surgery of the second section of the patient to obtain an autologous transplant often leads to high morbidity and complications; 4) implants of the cortical layer of the bone are difficult to molding to achieve compliance with the damaged area; 5) the existing equipment and equipment for selecting bone tissue is limited to the use of trephines and curettes, which limits the quantity and quality of tissue and requires surgery of the second site; 6) there is a shortage of modern synthetic materials for bone matrices, for example, compositions of calcium phosphate and calcium carbonate, silica glass, copolymers of lactic and polyglycolic acid and marine corals.

 Since these known technologies are not completely satisfactory, the authors of the present invention sought to improve them and created the invention described below.

SUMMARY OF THE INVENTION
The present invention provides a device and methods for collecting chips generated by the cutting action of cutting tools. The proposed device contains a tip adapted for use with a cutting tool, and a storage chamber attached to the tip for collecting and storing chips. When the cutting tool is inserted into the device, the latter acts independently of the cutting tool by providing rotation of the cutting tool relative to its longitudinal axis and translational movement of the cutting tool in and out of the device. During use, the chips accumulate in the collection chamber.

 The phrase “adapted for use with a cutting tool” means that the tip serves as a guide for the cutting tool and can also serve as a bearing for the cutting tool. The tip has a hole for installing the cutting tool. Features of the invention that allow the accumulation of chips in the storage chamber include the movement of chips along the channel under the influence of the cutting tool, the extraction of particles by translational movement of the cutting tool, and dropping particles by centripetal forces created by the rotation of the cutting tool.

 One exemplary embodiment of the invention further comprises a cap attached to the collection chamber, which cap is adapted for use with a cutting tool. The phrase "adapted for use with a cutting tool" means that this cap serves as a guide for the cutting tool and can also serve as a bearing for the cutting tool. The cap may have an opening for mounting the cutting tool and may have an additional attachment for mixing the contents of this attachment with the chips in the storage chamber.

 In another embodiment of the present invention, the device may further comprise a tool for cleaning the cutting tool. This device may have a flexible or rigid protrusion and may be mounted in the sleeve of the cleaning device attached to the collection chamber or cap. The protrusion for cleaning the cutting tool may be flexible to fit along the contour to the surface of the cutting tool, for example, be a wire, bristles or brush, or it may be rigid and formed to ensure mating or fit along the contour to the groove or transverse contour of the drill. The protrusion for cleaning the cutting tool may further comprise a finger sliding on the outer surface of the cutting tool to remove material, and may be located near the junction of the tip and the storage chamber.

 Aspects of other embodiments of the invention that contribute to the accumulation of particles in the collection chamber include the use of the cleaning device described above, and, for example, the use of suction using a vacuum line. These aspects are complemented by the cleaning and suctioning action of the above-described steps of channeling, removing and separating as the means by which the present invention provides for the collection of chips generated by the use of cutting tools.

 The tip of the tool may additionally have a tooth or multiple teeth to prevent slipping on the cutting surface. The tip can be spherical or rotary.

 In a preferred embodiment, the device further comprises a coaxially oriented cutting tool. The term “cutting tool” means a tool with a groove, for example, a drill, a boron, a grinding wheel, a rasp, a reamer, a mill, and the like, as well as a tool without a groove, for example a hole saw. The term “coaxially oriented” means that the cutting tool is mounted in the device body so as to be substantially centered in the device. The cutting tool may be provided with an adjustable stop, preferably a calibrated adjustable stop.

 In another preferred embodiment of the device according to the invention having a cutting tool, the latter is a drill. This drill can have a standard peak or a peak with a first side and a second side, the first side having a straight cutting edge and the second side having a series of grinding teeth.

 The cutting tool can be rotated manually, however, it can further comprise a means of rotating it to optimize the cutting effect on durable materials, such as metals. The preferred tool is an external motor.

 In another aspect of the invention, the device further comprises a device for expelling particles from the storage chamber through a tip for applying to any area. Such a device may be a plunger inserted through the cap. Another feature is that this device can be a double plunger that is inserted into the storage chamber after removing the cap.

 The storage chamber may further have a means for measuring volume. In one embodiment of the invention, the storage chamber has a transparent or translucent wall, and the volume measuring means includes volumetric marking on the wall. Such a device may further comprise a plunger for compaction of the collected chips to enable measurement of the compacted volume.

 Some parts of the device can be advantageously made in one piece to create, for example, a disposable element. Such elements may include a tip, a storage chamber and a sleeve of a cleaning device, or a tip and a storage chamber, or a cover, a cleaning device and a sleeve of a cleaning device.

 Another aspect of the present invention is a drill having an apex with a first side and a second side, the first side having a straight cutting edge and the second side having a series of grinding teeth. The chips obtained in the process of using a device equipped with a cutting tool in the form of such a drill are another aspect of the present invention.

 In another embodiment of the device according to the present invention, the collection chamber further has an opening for connection to a vacuum line to provide suction.

 In an example embodiment of the invention, skeletal tissues are selected using the device of the invention. In yet another preferred embodiment of the invention, this selection is performed aseptically to obtain material for the transplant. The term "skeletal tissue" means the bony or more or less cartilage body, bone, bone marrow, cartilage, ligaments, cancellous bone or tendon, including their inherent physiological factors, for example, growth factors, blood, biochemical or cellular elements or components . The term "aseptic conditions" means those sterile or almost sterile conditions that are accepted in surgical practice. When reading this description, it will be apparent to those skilled in the art that asepsis should cover the sterilization of instruments, surfaces, solutions, etc., the use of sterile clothing, masks, etc., and, for example, ambient air filtration. Sterilization can be carried out, for example, by exposure to heat, ultraviolet radiation, wiping with alcohol swabs or using antimicrobial agents.

 Another embodiment of the invention is a material transplant system. This system comprises a device according to the invention with or without a cleaning device equipped with a cutting tool, and means for moving the chips to another site of use, for example, an implantation site. In an exemplary embodiment, the chips are bone chips, and the system is a sterile tissue transplant system. The material transplantation system may further have a tissue processing means, for example an encapsulation nozzle. The phrase "means for moving chips to another site of use" means any means for moving chips from a site for their selection to another site.

 Another embodiment of the invention is a method of using the tissue transplantation system described herein for aseptic transplantation of skeletal tissue from a first site to a second site. This method includes the operation of aseptic removal of skeletal tissue from the first site using the material transplantation system described here and aseptic implantation of skeletal tissue at the second site. Before implantation, skeletal tissue may be treated in a second region, which treatment may include washing, grinding, tissue separation, acid or base addition of encapsulating substance or therapeutic agents, including (but not limited to) the addition of drugs and growth factors . In particular, the first region and the second region may be in the same patient, so that the implant is an autologous transplant.

 The device according to the present invention is useful in any application where chips are collected. Chips can be collected because the materials processed by cutting can be valuable, for example, rare and expensive, or have special properties, or when their loss is undesirable. On the other hand, the shavings can be toxic or dangerous, and the collection of such shavings is desirable to minimize any danger. Toxicity can be caused by volatility, flammability, radioactivity or biohazardous features, such as the presence of viruses such as human immunodeficiency virus.

 During the machining of hazardous materials, the device and methods of the present invention provide increased safety. Materials that are easily oxidized and are flammable, such as titanium, magnesium and sodium, can be safely collected in the system, since oxygen pressure can be controlled inside the system. The design of the device minimizes any fire hazard through reduced access of oxygen to a virtually closed system. Vacuum can be used to remove powdery chips and further reduce the oxygen pressure in the storage chamber. In addition, the system can be purged with an inert gas, such as argon, to minimize the risk of ignition.

 In industrial applications, it is possible to mechanically process gold, silver, platinum or uranium and collect chips for reuse, rejection, or, for example, to comply with safety and environmental requirements. This device can also be used in a microgravity environment to collect chips that cannot otherwise be held. The term "microgravity environment" means any medium in which gravity is less than on the surface of the earth, for example, the environment inside a space station.

 In medical applications, the collection of skeletal tissue chips is intended, in particular, to be used in orthopedics or dentistry, where it is necessary to drill a bone and / or bone marrow, or aseptically select these materials for subsequent medical use. Selected skeletal tissue can be used as transplants to facilitate healing of bone lesions or to facilitate implant survival. If the selected tissue is biohazardous, the proposed collection system increases the safety of handling such tissue, keeping it substantially isolated until disposal.

 According to the inventors, specific materials for cutting using the device according to the present invention are skeletal fabrics, metals, ceramics and polymers. The term "ceramic" means a material made of silica ceramics, silica glass, calcium carbonate, calcium phosphate, hydroxyapatite, porcelain or, for example, aerospace ceramics. The term "aerospace ceramics" means materials such as fibrous refractory composite insulation, thermoplastic syntactic foam, ceramic matrix composite, and the like. The term “polymer” means medical grade polymers, for example polymethyl methacrylate, polycarbonate, polystyrene, polyvinyl chloride, silicone elastomer, and the like.

 The device according to the present invention can be used by performing the following operations of an exemplary orthopedic procedure: 1) placing the device on a bone to localize the cutting site and provide a guide for the cutting tool, in this example a drill; 2) the placement of the drill in the device; 3) drilling in a manner accepted in clinical practice; 4) removing the drill from the device; 5) holding the device at the drilling site to combine the tip hole and the drilled hole to ensure the bone marrow tissue is lifted with blood into the tip and the storage chamber; 6) removal of the device from the site; 7) compaction of the selected material inside the device; 8) measurement of the volume of material collected; 9) extrusion of the compacted material through the tip or removing it from the opening of the storage chamber; and 10) implantation of material in a second region of the same patient.

 In this example, out of ten operations, the independence of the device from the drill is demonstrated, if you pay attention to the fact that the drill was used with the device in only three operations (2, 3 and 4), the fabric was assembled in three operations (3, 4 and 5) and tissue manipulations in the device were carried out in six operations (3, 4, 5, 6, 7, 8, and 9). In this example, in addition to collecting tissue, the device was used to localize the drilling site, support the drill, guide the drill, adjust the drilling depth by using an adjustable stop, protect surrounding tissues from being caught by the cutting edge of the drill, and also to collect, protect, store and move tissue from compliance with sterility.

 The present invention has the following advantages: 1) the device can be adapted to special procedures and cutting requirements; 2) the device provides a quick and accurate determination of the volumetric amount of the collected material; 3) the device facilitates the efficient use and placement of the collected chips to another site; 4) the invention excludes the practice of culling and loss of valuable materials; 5) the invention can be used with conventional drill motors and drills; 6) the invention effectively combines three processes: creating a channel, extracting and dumping to collect chips; 7) the invention can be adapted to numerous types of cutting tools; 8) the invention can be used to collect crumbs of valuable metals and dust; 9) the invention can be used to automatically collect radioactive material; 10) the invention can be used to reduce fire hazard during the cutting of oxidizable materials; 11) the invention can be used to localize and support the cutting tool; 12) the device for cleaning the grooves according to the invention can rotate with the drill during rotation and translational movement of the latter; 13) the device can be held by hand; 14) the invention does not depend on the cutting tool in many cases of its use; 15) efficient collection through channeling, extraction and discharge processes can be further improved by the addition of cleaning and suction processes.

 Other advantages of the present invention that are obvious when used to select skeletal tissue include the following: 1) the invention makes it possible to select spongy or other bone and / or brain material in several areas of the donor; 2) the invention makes it possible to optimally process viable skeletal tissue for transplantation by selecting it with small particles with a large surface area and washing the vital elements of the bone marrow; 3) the invention minimizes the biological hazard associated with the removal of chips from human bones; 4) the invention reduces the possibility of a patient's disease by reducing the time of tissue selection and allows the use of minimally invasive surgical methods; 5) the invention reduces the concentration of mechanical stress and the likelihood of iatrogenic cracks and diseases.

 According to a long-established agreement on patent law, the first time a singular attribute is mentioned (English articles "a" and "an") when used in this application, including the claims, means "one or more".

BRIEF DESCRIPTION OF THE DRAWINGS
Additional objectives and advantages of the present invention will become apparent upon consideration of the drawings and the following description of preferred embodiments of the invention.

 FIG. 1 is a sectional top view of one embodiment of a device according to the present invention with a drill installed therein.

 FIG. 2 is an exploded sectional view of some components of an embodiment of the invention.

 FIG. 3a is a sectional view of another embodiment of the invention mounted on a bone before drilling.

 FIG. 3b represents an example embodiment of the invention during a tissue extraction operation. The drill (150) rotates clockwise (T).

 FIG. 4a is a detail sectional view of some components of an embodiment of the invention.

 FIG. 4b is an image of a device tip with means for engaging with a bone surface and a hinge to provide a seal between the tip and bone.

 FIG. 5a and 5b represent an image of a drill design with a groove that simultaneously processes grinding and cutting near the tip to optimize chip morphology, and an image of a large groove with a small input angle to facilitate chip movement up the drill and inside the tip (100).

 FIG. 6 is a schematic illustration of an example embodiment of the invention that is proposed for aseptic tissue transplantation from a first site to a second site using the device of the present invention. The selected tissue can be processed to further improve its inducing bone healing potential.

 FIG. 7 represents a double plunger installed in the storage chamber of a device according to the present invention for extruding the collected chips.

 FIG. 8 is a sectional view of a double plunger.

 FIG. 9a is a plan view of a rotating groove cleaner (600) having a rigid protrusion (610) for a drill with two conventional grooves.

 FIG. 9b is a top view of a typical rotary cleaning tool (620) with flexible bristle-shaped protrusions (630) for use with a drill, conical reamer, bur, rasp or saw.

 FIG. 9c is a top view of a rotary tool for cleaning (640) reamers grooves having rigid or flexible protrusions (650) for reamers with a large number of grooves.

LIST OF POSITION NUMBERS
10,100 tip
103 spherical tip
106 tip teeth
20,110 storage camera
120 sleeve cleaning device
130 drill cleaner
30,140 cap
150 drill
160 groove cleaner
170 drill groove
180 swivel tip
183 tabs for fixing the tip
186 teeth rotary tip
190 spongy bone
193 cortical bone
195 bone chips
200 cutting edge
210 grinding teeth
220 cutting edge drill
230 groove
240 shank drill
401 storage camera
402 tissue suction line
403 fabric tank
404 vacuum pump
405 bone chips
406 vane pump (with roller blades)
407 fabric separator
408 valve
409 encapsulating substance
410 encapsulation nozzle
411 applicator
412 encapsulated tissue
413 bone
414 iliac crest
500 tip plunger
510 storage chamber plunger
520 plunger head
530 end face of the plunger
540 extrusion surface of the storage chamber
600 drill groove cleaner
610 ledge groove drill
620 typical cleaning tool
630 protrusion of a typical cleaning tool
640 sweep groove cleaner
650 protrusion for recess groove
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS FOR CARRYING OUT THE INVENTION
The present invention in one preferred embodiment provides surgical equipment that acts as a backup of a cutting tool for efficiently cutting and collecting skeletal tissue, including bone and cartilage. In addition, the invention provides for the transfer of selected tissue to the implantation site. If the selection site and the implantation site are in the same subject, the graft is called an autologous graft or an autograft. A transplant of this type is as close to ideal as it can be achieved, since it has inherent growth factors and matrix material and excludes immune rejection. If the selection site and the implantation site are in different subjects, the graft is called an allogeneic graft or an allograft, and there is a possibility of an immune rejection of such a graft by the recipient. The implantation site may be structural damage or a site of bone or cartilage, for example, in the case of orthopedic or dental implantation.

 Freshly selected bone or cartilage can be defined as viable and inducing. This means that freshly selected tissue contains growth factors and matrix material, which, when transplanted to a donor patient, stimulate bone or cartilage healing. Typical transplant growth factors and matrix material contain transforming beta growth factor, fibroblast growth factor, morphogenetic bone proteins, biocompatible support material and natural matrix material that facilitate the bonding of large cracks or filling of bone lesions, but are not limited to this list. It is assumed that growth factors, both mentioned and others, can be added to the selected material to further facilitate bone healing at the implantation site.

 In the preferred embodiment of FIG. 1 and FIG. 3a, the surgical device according to the invention makes it possible to aseptically collect chips from bone and cartilage and contains a tip (10, 100) that contacts the bone and guides the cutting tool, a storage chamber (20, 110), in which these particles are accumulated and held, and a cap (30, 140) with an opening that serves as the upper guide of the cutting tool (150) and bearing. The tip (10, 100) and the cap (30, 140) as a bearing jointly center the cutting tool (150) and allow this tool to be rotated manually using a hand chuck or using an external motor. When equipped with a cutting tool, such as a drill (150), as shown in FIG. 1, 3a and 3b, the drill (150) is inserted longitudinally into the housing of the claimed device. This drill bit is used for cutting and grinding chips (195) from the bone near the tip of the surgical device and translationally moves the bone chips (195) up the tip into the storage chamber (110) for tissue.

 The terms “sleeve” and “bearing” are used interchangeably throughout this description to illustrate that the surface relative to which the cutting tool rotates can be a simple sleeve or a roller bearing rotating together with the cutting tool and not having sliding contact between the surface of the cutting tool and the ring bearing.

 The present invention effectively and simultaneously combines three processes: creating a channel, extracting and separating the chips generated by using cutting tools in the storage chamber. When the cutting tool is inserted into the surgical tool, the latter acts independently of the cutting tool, allowing the cutting tool to rotate about its longitudinal axis and translate in and out of the surgical tool without the need for angular rotation speed or translational motion characteristics of the drill and its motor. During operation, the chip rises along the channel due to the grooves, is removed by translational movement of the drill and is reset under the action of centripetal force arising from the rotation of the drill. The chips can be removed by the fourth process — by emptying the collection chamber by suction.

 A cutting tool may be a tool with grooves, for example, a drill, a bur, a grinding wheel, a rasp, a reamer, a mill, and the like. In another embodiment, a cleaning tool (130, 600, 620, 640) is provided for separating chips (195) from the tool (170), which causes particles to accumulate in the storage chamber (110) when the cutting tool is removed from the surgical tool. The use of a cleaning device adds a fifth process, a cleaning process, to the previously described processes of channeling, extraction, discharge and suction of particles for a more efficient and complete separation of all chips from the cutting tool. If the cutting tool has a groove (230), such as a drill (150), the cleaning tool (130, 600, 620, 640) can be designed to fit into the grooves (230) of the cutting tool. The cleaning device (130, 600, 620, 640) is coaxially oriented relative to the cutting tool and may have a protrusion (160, 610, 630, 650) in its hole, which is included in the grooves (230) of the cutting tool for cleaning these grooves from chips, when the cutting tool is pulled through the cleaner. The cleaning device (130, 600, 620, 640) can freely rotate inside the storage chamber or adjacent bearing housing during rotation or translational movement of the cutting tool in a surgical instrument. In an embodiment having a cleaning device for the drill, the cleaning tool (130, 600, 620, 640) of the drill rotates with the drill (150) and allows translational movement of the drill (150). The tool for cleaning (130, 600, 620, 640) of the drill slides along the inner surface of the hole and is mounted inside the sleeve (120) of the tool for cleaning. A tool for cleaning the grooves of the drill is included in the grooves of the drill to clean the grooves of the drill of chips from bone and blood. This cleaning device rotates inside the storage chamber during rotation and translational movement of the drill in the storage chamber.

 The protrusions may be cams (610, 650), bristles, wires, brushes or threaded protrusions (630). The cleaning tool (620) may be adapted for a conical cutting tool. In one embodiment of the cleaning tool (620), the protrusions (630) are similar to wheel spokes and are flexible to fit conical reamers with one or more grooves. Such a cleaning device (620) rotates in the housing in such a way as to minimize the rotational effect of the drill on the spoke-like protrusions (630), while simultaneously translating and cleaning conical drills with grooves or reamers. In a surgical instrument, a cleaning tool (640) can be used for reamers with unevenly projected protrusions (650) corresponding to the shape of the grooves.

 Cutting tools can also be tools without grooves, such as a hole saw. Hole saws having a hole and cutting teeth at one end are used to core the material to produce a round hole. In another embodiment, adapted for use with a hole saw, cutting-separated material rises through the hole of the saw until it reaches a portion of the hole with a larger internal diameter compared to the hole of the working end of the saw, where this material accumulates in the storage chamber. In this embodiment, the storage chamber rotates with the saw inside the stationary body. The surgical instrument may have a tip and a body similar to a storage chamber of a preferred embodiment in which the ring saw could rotate with the storage chamber. A cap attached to the proximal end of the casing could serve as a bearing and the end of the storage chamber located inside the saw.

 The surgical tool may also contain a device that is installed in the storage chamber and acts as a plunger (500, 510) to push chips (195) from the bone from the storage chamber (20, 110) through the tip (10, 100) for applying to the surgical site . During operation, the plunger (500, 510) is progressively moved in the opening of the storage chamber (20, 110) to squeeze the chips from the tip (10, 100). The end surface (530) of the plunger is formed from a flexible material and has a flatter taper angle compared to the extrusion surface (540) of the storage chamber, so that upon contact, the particles are first pressed along the edge of the end surface (530) of the plunger to the contact area of the extrusion surface (540) . As the end surface of the plunger changes shape due to the flexibility of its material, the contact area increases in area in the direction of the tip hole (10, 100). As a result, all materials are extruded into the tip (10, 100). The tip is cleaned by the tip plunger (500) after the plunger (510) reaches the end of its full stroke.

 The surgical instrument according to the present invention may also further comprise a prefix containing biocompatible materials, pharmaceuticals or biological substances for mixing with the bone structure. The prefix would be attached to the opening of the storage chamber (20, 110), and it is a means for mixing the contents of the console with shavings (195) of bone inside the storage chamber (20, 110). This attachment may have a strainer to filter chip size or a mixer to mix the contents of the attachment with bone chips (195). The prefix can be used in conjunction with the plunger to combine simple and accurate delivery with bone chip processing to enhance efficacy and facilitate bone healing.

 The surgical instrument preferably has a cylindrical shape, although the instrument may be of a different shape. Alternative basic forms may be elongated; the tool should have a shape that facilitates its use, for example, have a handle preferably of an ergonomic configuration. An example embodiment of the invention that has been manufactured and used in surgery is a cylinder having a diameter of approximately 31.75 mm and a length of 101.6 mm. It is intended to use cylinders with a diameter of approximately 9.53-12.7 mm and a length of approximately 25.4 mm for small bones. In industrial sets, it is supposed to use a cylinder having a diameter and length of up to about 305 mm.

 Materials suitable for the manufacture of the device include, for example, stainless steel, delrin (acetalviniplast), polymethyl methacrylate and polyethylene, but not only these materials. The tip, grooving device and sleeve can be made of metal and are preferably made of surgical stainless steel. Alternative materials may be used, for example titanium, cobalt or titanium nitrate coated steel. The cap, collection chamber and purifier body are preferably made of injection molded high density polyethylene, but can be made of polymers including delrin, nylon, polymethyl methacrylate, polyester, polyvinyl chloride and polycarbonate, but not only these materials. In general, metal parts should be resistant to wear caused by the cutting tool and should be selected from the group of biocompatible metals so that a small amount of wear products does not cause harmful contamination of the collected fabric. In general, polymer parts can be made of any material that is easily molded and sufficiently durable to use.

 The tip (10, 100, 103) in contact with the cutting surface without penetrating into it serves as a guide or support and bearing for the cutting tool (450) while lifting the selected fabric through the channel into the storage chamber (20, 110). In an embodiment with a cleaning device (130, 600, 620, 640) or in an embodiment without a cleaning device, the tip (10, 100) of the device forms the lower part of the tissue storage chamber (20, 110) and may have a protruding edge to increase stability and fixation in the storage chamber. This tip creates a channel and means for moving the chips into the storage chamber (20, 110). The tip (10, 100) has a means for eliminating the sliding along the bone and holding the chips (195) from the bone in the groove (170) of the cutting tool for feeding this chips up the channel into the tip (10, 100) and the storage chamber (20, 110) .

 To prevent slipping and directing bone chips (195) into the canal, a serrated edge or sharp teeth (106) of the tip can be used located directly on the cylindrical part of the tip (10, 100) or on a rotary tip (180) held by elastic protrusions (183) for fixing the tip. The pivot tip (180) rotates relative to the lower end of the optionally mounted tip (103) with a spherical end in order to provide good contact with the cortical layer (193) of the bone.

 The housing of the storage chamber (20, 110) can be attached to the cap (30, 140) or the sleeve (120) of the cleaning device. In the manufacture for attachment to the cap (30), the open end of the storage chamber (20, 110) may have a precisely located protrusion on the inner surface for fastening to the cap. The storage chamber (20, 110) has no moving parts and facilitates the movement of the chips up the grooves of the cutting tool, the extraction of tissue through the tip and the discharge of chips for accumulation in the storage chamber. The collection chamber (20, 110) can be further improved by the presence of an opening for connection to the suction line (401) in order to facilitate the collection of chips and blood. The storage chamber (20, 110, 401) may have means for measuring the volume of collected tissue, not limited only by volumetric marking, or by transparent or translucent external walls, which together with volumetric calibration can be used to measure uncompressed volume. The plunger (500, 510) can be used to compress bone chips to measure the compacted volume.

 A cap (30, 140) can be attached to the storage chamber (20, 110) or sleeve (120) of the cleaning device. The cap (30, 140) may have a groove on the outer diameter near one of the ends for fixing with a protrusion in the opening of the storage chamber (20, 110). Other types of connections may include threads, O-rings, or quick disconnect elements. The cap (140) may contain a device for cleaning (130) the grooves, which is fixed by the use of a press fit cylindrical bearing.

 An example embodiment of the invention is shown in FIG. 3a in contact with the cortical layer (193) of the bone before drilling. The invention is shown in operation in FIG. 3b during drilling of the cortical layer (193) and spongy substance (190) of the bone, moving the shavings (195) from the bone up the grooves (170) of the drill and accumulating them in the storage chamber (110).

 In one aspect of the invention, a surgical instrument is intended for use with a drill. A drill having an apex that simultaneously crushes and cuts the bone (200, 210) in order to optimize the particle size of the bone for specific transplantation purposes is an aspect of the invention (see FIGS. 5a and 5b). The top of the drill has teeth (210) and a cutting edge (200) at the entrance to its grooves for grinding and cutting the bone in the process of creating holes in the bone. The geometry of the teeth and the cutting edge can be selected from the conditions for controlling the particle size of the bone chips. The drill may have a large volume groove with a small angle of inclination to facilitate the movement of bone chips into the tissue storage chamber.

 Drills of most of the known constructions can be used, and the quality of bone chips (195) can be optimized by using a special drill in an embodiment of the invention. The top of this special drill has a straight cutting edge (200) on one side and a series of grinding teeth (210) on the other side. The grinding teeth (210) protrude from the top of the drill beyond the boundaries of the cutting edge (200) and serve to grind and loosen the material so that the cutting edge (200) separates and directs the material to the entrance to the groove (230).

 Other aspects of the drill that are offered as part of the present invention include the following. The cutting edge (220) of the drill can be optimized for various applications using grooves with different volumes and angles to translate the shavings (195) from the bone or bone marrow tissue. The shank of the drill (240), which does not have grooves, is fixed in the drill motor and serves to stop the translational movement of the drill through the tool for cleaning (130) the drill due to the occurrence of an obstacle between the tool for cleaning (160) grooves and the groove-free portion of the shank (240) of the drill. The shank of the drill (240) can be installed with a calibrated adjustable stop to ensure accurate control of the penetration depth of the drill.

 A surgical instrument may be a disposable device, i.e., a disposable module, provided to the user in sterile packaging. In particular, it is planned to create models adapted for the installation of drills with diameters of 2-4, 4-6, 6-8, 8-10 and 10-12 mm.

 Another embodiment of the invention comprises the surgical instrument described above, and furthermore comprises means for transferring the selected tissue to a second site with optional treatment of the selected tissue. In this embodiment, a storage chamber (401) is connected to a suction line (402) to move bone chips (405) and fluid collected in one surgical site, such as an iliac crest (414), so that they are stored in a reservoir (403 ) for fabric. The vacuum in the system is created by a vacuum pump (404) connected to a tissue reservoir (403). The collected material stored in the fabric reservoir (403) is supplied by a vane pump (406) with roller blades to the fabric separator (407). The tissue separator (407) may contain strainers and other filters, centrifugal devices or other devices for separating tissue and cells, as well as solutions of acids and bases to modify the collected tissue. The tissue transplantation system may include a pump, a filter, a centrifuge, a mixing chamber, a settler, a tube, and the like. This system may have an applicator for implanting the collected skeletal tissue. Skeletal tissue can be selected from several places, for example, from the rib, fibula, ilium, skull, sternum, tibia, etc.

 For example, a centrifuge can be used to fractionate selected tissue and remove red blood cells and / or white blood cells; or the selected tissue can be chemically washed to increase the bone formation inducing potential of various proteins and cells while maintaining their viability. The treatment may include the steps of increasing the bone-forming potential of the specified bone chips, not limited to filtration, washing with water, grinding bone chips and washing with solutions of acids and bases.

 The processed tissue components can be combined or separately fed to the implantation site through a valve (408) into an encapsulation nozzle (410), where encapsulating substances, for example, algin, poly-L-lysine, collagen, lactic acid polymer, polyglycolic acid, can be combined with this tissue acid, methyl cellulose, glycerin, saline, calcium phosphate or calcium carbonate from the reservoir (409) for encapsulating substances. The encapsulating substance together with the tissue (412) or only the tissue itself can then be applied to the damaged area of the bone (413) using an applicator (411). The volumetric pump (406) creates pressure to move the material through the processing step to the implantation site.

 The spongy bone is rich in cells, quickly connects to the recipient's bone and is resistant to infection. Compared to solid bone transplants, particulate or pasty bone materials offer significant advantages. The benefits of fresh, autogenous bone chips include: a large transplant surface that facilitates vascularization and reconstruction. Healing should occur under the influence of the "field phenomenon" simultaneously throughout the damage. Irregularly shaped lesions can be filled in more carefully to form a closer and more extensive contact between the recipient site and the graft tissue, and only minimal surgical access is needed to fill in lesions with large depressions. In addition, the bone cells in the bone cancellous transplant in contact with well-vascularized supporting tissue have survival, and storing the selected bone cancellous material in normal saline ensures cell survival in the range from 95 to 100% even after work lasting up to four hours (see Marx R. et al. J. Oral Surg. 37: 712-718, 1979).

 An aspect of the present invention is the use of the tissue transplantation system described above in combination with the addition of growth factors and matrix material to improve the healing of bone damage. It is assumed that the addition of these factors and material optimizes the condition of skeletal tissue. Such factors and materials include, for example, transforming alpha and beta growth factors, morphogenetic bone proteins, platelet growth factor, epithelial growth factor, fibroblast growth factor, vascular permeability factor, mitogens, mesenchymal cells, progenitor cells and natural matrix bone material.

The fabric blank can be divided in time with a transplant to its donor or other recipient. One of skill in the art would recognize from this description how to use the device of the present invention if tissue is taken from one patient and
transplanted to another patient.

 In the operation of the present invention, drilling of skeletal tissue for reconstructive surgery or for the insertion of orthopedic, dental, oral or maxillofacial implants, for example plates, screws or rods, is performed aseptically. Chips generated during drilling are usually discarded, but when using the present invention, these chips are collected and can be placed around the implant to improve the connection of the implant and facilitate healing. The present invention is used in combination with conventional drills and drill motors.

 The method involves aseptic collection and transfer of bone chips and / or bone marrow components for immediate transplantation. Tissue collected using the surgical device of the present invention is a cortical and cancellous bone substance in combination with bone marrow and blood tissues that form a paste-like material for transplantation. This material has the properties of processing pasty materials, a large surface area and a wide open structure. These characteristics of the methods of the present invention facilitate handling, vascularization and reconstruction and contribute to the creation of inducing bone-forming support to improve the healing of the surgical site.

 In the practical application of the preferred embodiment, the drill (150) is inserted through the cap (140), the sleeve (120) of the cleaning tool, the cleaning tool (130) of the drill, the storage chamber (110) and the tip (100). When the drill (150) rotates, a bone is drilled. Bone shavings (195) are limited in the groove (170) of the drill with a tip (100).

 Continuous rotation of the drill (150) causes the translational movement of bone chips (195) from the bone up the inner hole of the tip (100). Chip (195), moved upward along the tip (100) and into the accumulation chamber (110), falls out of the grooves (170) of the drill and is collected in the accumulation chamber (110). The bone chips remaining in the tip (10, 100) for the drill can be advanced into the storage chamber (20, 110) by translational movement of the drill, and the chips remaining in the grooves (170) of the drill are removed from these grooves (170) by centripetal force, suction, or using a drill cleaner (130).

 The drill cleaning tool (130) rotates freely in the sleeve (120) of the cleaning tool about its axis coinciding with the axis of the drill (150). A device for cleaning (160) the grooves, which is part of the device for cleaning (130) the drill, enters the grooves (170) of the drill and cleans the remnants of bone chips that are not collected in the storage chamber (110). The drill cleaner (130) rotates with the drill when the latter rotates about its longitudinal axis or when the drill moves progressively through the tip (100), the storage chamber (110) and the drill cleaner (130).

 The tip (100) is connected to the housing of the storage chamber (110) for tissue. The storage chamber (110) is connected to the sleeve (120) of the cleaning device, which serves as a bearing surface and a guide for the cleaning tool (130) of the drill. The tool for cleaning (130) of the drill rotates freely in the sleeve (120) of the tool for cleaning and is limited to the cover (140), which is connected to the sleeve (120) of the tool for cleaning. The tip (100), the storage chamber (110) and the sleeve (120) of the cleaning device can be made in the form of a single module and made as a device for single use.

 The surgical instrument is used with conventional surgical drills. A drill with the appropriate diameter, groove length and full length of the entire drill is inserted into the appropriate model of the surgical device from the side of the cap. The surgical instrument is held with one hand, and the tip is placed on the bone at the drilling site. As the bone is drilled, fragments of the bone and / or bone marrow move up the grooves of the drill, pass through the tip and passively drop out of the grooves into the storage chamber. The drill can protrude beyond the tip of the device by approximately up to 76-127 mm, and the device can be moved in an arc to select tissue on the conical sections of the bone. When the drill is progressively diverted from the bone within the device and moves inward and outward from the tip, the rotational action further contributes to the displacement of material from the grooves into the storage chamber, and in an embodiment having a cleaning device, moving the drill through the latter serves to displace the material into the storage chamber .

 The description of the examples of implementation and their work is not given to limit the design and scope of the invention, but to expand the description of the invention in order to cover any method or device that uses the surgical device according to the present invention and the goal is the selection and processing of bone tissue or bone tissue brain for subsequent transplantation.

 Although the present invention has been described with some degree of specificity, it will be apparent to those skilled in the art from the previous description that many other alternatives, modifications, and changes are possible. In this regard, it is assumed that all of these alternatives, modifications and changes that do not go beyond the essence and scope of the present invention, will be covered by the claims.

 The following example is included in the description to demonstrate a preferred embodiment of the invention. Specialists in the art should understand that the methods described in this example are known to the inventors as well-established in practice and, therefore, can be considered preferred examples of the practical application of the invention. However, it will be understood by those skilled in the art from the preceding description that many changes are possible in the described specific embodiments to produce similar or identical results without departing from the spirit and scope of the invention.

EXAMPLE
Skeletal tissue harvesting
The surgical instrument of the present invention was manufactured and tested on a corpse and live animals. The device was used in conjunction with a conventional drill on the thigh bones of a fresh corpse. Bone chips were collected after several revolutions of the drill. The chips moved up the groove within the tip. The chips left the groove after passing the tip and fell into the collection chamber. Through the window of the storage chamber, the white color of the cortical layer of the bone was visible, and crumbs of the spongy bone were covered with a small amount of blood. Six holes with a diameter of 6.9 mm were drilled to a depth of about 2 cm. At each new hole, the storage chamber continued to fill. A large amount of bone tissue collected in the collection chamber soon began to impede the view of the drill.

 During drilling, it was noted that some chips remained in the grooves. To test the operation of the grooving tool, the drill bit was removed. After removing from the tool, it was noted that the grooves were cleaned, and it was seen how the chips fell into the collection chamber. The action of the rotating cleaning device was smooth and did not cause the drill to jam during drilling or extraction. Upon reaching the desired drilling depth, the drill could be quickly inserted and withdrawn to collect additional bone tissue from the edges of the drilled hole or to pump blood into the storage chamber flowing to the drilling site. Using a vacuum in combination with an instrument could facilitate the collection of more blood, if clinically beneficial.

 In one embodiment of the invention, the cap and bearing of the cleaning device are made as a single module, which module can be removed together with the rotating groove cleaning device. The storage chamber and the tip can also be manufactured as a single module. The plunger assembly attaches to the collection chamber and facilitates the separation of the selected bone tissue from the instrument. This plunger assembly allows extruded bone to be squeezed out of the collection chamber through the tip to facilitate application of this tissue to the damaged area during connection or implantation. With an attached plunger assembly, the instrument allows placement of collected bone and blood.

 After collection, the storage chamber was emptied of bone tissue. It was noted that the bone tissue consists of large chips with different sizes of approximately 0.5 x 4 x 8 mm. The chips were covered in blood, but there was no free liquid in the collection chamber.

 Tissue volume was determined and volume values were compared with theoretical values based on the size of the drilled hole. In addition, the mass of tissue was determined, and the mass values were compared with the theoretical mass, determined by the density of the bone area multiplied by the volume of the drilled hole. Comparison data of tissue collection by volume are shown in Table 1, and mass comparison data is shown in Table 2.

The surgical instrument was tested on live animals to select tissue from the iliac crest and the proximal tibia metaphysis. Two holes were drilled in each place. The observation results while drilling the bones of a fresh corpse and areas on live animals are consistent. Bone tissue was harvested to produce bone chips slightly covered in blood. The blood in the collection chamber was not collected in sufficient quantity to form free fluid. Both drilled holes in the tibia gave 0.45 cm 3 or 0.48 g of bone particles. Both drilled holes in the iliac crest gave 0.91 cm 3 or 1.09 g of bone particles.

 These data show that the surgical instrument according to the invention is easy to use and provides the collection of viable bone tissue for placement on the damaged area. Using this tool, a hole drilled in the bone to connect the implant or to install a screw can be a source of highly inductive tissue that can accelerate the healing process of the bone, fill in extensive bone damage, or facilitate the connection of unstable or diseased joints.

 All compositions and methods described and claimed herein can be manufactured and carried out without undue experimentation as described herein. Although the compositions and methods of the present invention have been described as preferred embodiments, it will be apparent to those skilled in the art that non-deviating changes may be made to the composition, methods and operations, or the sequence of operations of the method described herein. from the concept, essence and scope of the invention. More specifically, it should be apparent that certain agents that are chemically and physiologically related may replace the agents described herein with the same or similar results. Those skilled in the art will appreciate that all such substitutions and modifications are deemed to be within the spirit, scope, and concept of the present invention as defined in the appended claims.

Claims (45)

 1. A device for collecting chips, containing a tip with a hole for installing a cutting tool having a groove, and when installing a cutting tool having a groove, the tip and groove form a closed channel, and a storage chamber attached to the tip or made in one piece with it, for collecting and storing chips, and when using the device provides rotation and translational movement of the cutting tool in and out of the device for moving the chips along the channel, its extraction or discharge and for the purpose of accumulating chips in the storage chamber.
 2. The device according to claim 1, characterized in that it further comprises a cap attached to the storage chamber and intended for use with a cutting tool.
 3. The device according to claim 1 or 2, characterized in that it further comprises a cleaning device.
 4. The device according to claim 1 or 2, characterized in that it further comprises a coaxially oriented cutting tool.
 5. The device according to claim 4, characterized in that the cutting tool is a drill, a boron, a grinding wheel, a rasp, a reamer, a cutter or a hole saw.
 6. The device according to claim 4, characterized in that the cutting tool is a drill.
 7. The device according to claim 4, characterized in that the cutting tool is equipped with an adjustable limiter.
 8. The device according to p. 6, characterized in that the drill has a top with a first side and a second side, the first side having a straight cutting edge and the second side has a series of grinding teeth.
 9. The device according to p. 4, characterized in that it further comprises a means of rotation of the cutting tool.
 10. The device according to claim 9, characterized in that the means of rotation of the cutting tool is an external engine.
 11. The device according to claim 1 or 2, characterized in that it further comprises a double plunger.
 12. The device according to claim 1 or 2, characterized in that the tip further comprises a tooth.
 13. The device according to claim 1 or 2, characterized in that the tip is made spherical.
 14. The device according to claim 1 or 2, characterized in that the tip is made rotatable.
 15. The device according to any one of claims 1, 2 or 11, characterized in that the storage chamber further comprises means for measuring volume.
 16. The device according to clause 15, wherein the storage chamber has a transparent or translucent wall, and the means for measuring volume includes volumetric marking on the wall.
 17. The device according to claim 3, characterized in that it further comprises a sleeve for cleaning devices. moreover, the tip, the storage chamber and the sleeve of the cleaning device are made in one piece.
 18. The device according to claim 2, characterized in that it further comprises a cleaning device and a sleeve of a cleaning device, wherein the cap, the cleaning device and the sleeve of the cleaning device are made in one piece.
 19. The device according to claim 3, characterized in that the cleaning device has a flexible protrusion for cleaning the cutting tool.
 20. The device according to claim 3, characterized in that the cleaning device has a hard protrusion for cleaning the cutting tool, while the protrusion is adjacent to the groove of the cutting tool.
 21. The device according to claim 1 or 2, characterized in that it further comprises a finger for cleaning the cutting tool, while the finger is located at the junction of the tip and the storage chamber.
 22. The device according to claim 4, characterized in that the cutting tool has a top with a first side and a second side, the first side having a straight cutting edge and the second side has a series of grinding teeth.
 23. The device according to claim 2, characterized in that the storage chamber further comprises an opening for communication with the vacuum line.
 24. The device according to claim 1 or 2, characterized in that it further comprises a prefix for processing chips.
 25. A drill having a tip with a first side and a second side, characterized in that the first side includes a straight cutting edge, and the second side includes a series of grinding teeth.
 26. A material transplant system containing the device according to item 23, equipped with a cutting tool, and means for moving chips to the place of transplantation.
 27. The system for the transplantation of materials according to p. 26, characterized in that it is sterile.
 28. The system for the transplantation of materials according to p. 26, characterized in that the materials are chips from biological tissue, and the system further comprises means for processing chips from tissue.
 29. The system for the transplantation of materials according to p. 28, characterized in that the means for processing chips from biological tissue contains a nozzle for encapsulation.
 30. The method of transplantation of materials, which consists in the fact that it uses the system for transplantation of materials according to item 27 for skeletal tissue, aseptically transplanted from the first section to the second section.
 31. The method according to p. 30, characterized in that the skeletal tissue is processed before transplantation to the second section.
 32. The method according to p, characterized in that the treatment is washing, grinding, filtering, separating, adding acid, adding a base, adding an encapsulating substance, adding a drug or adding a growth factor.
 33. The method according to p. 30, characterized in that the first section and the second section are in the same subject.
 34. The method of collecting chips, which consists in the fact that it uses the device according to claim 1 or 2 for collecting chips from bone, metal, ceramic or polymer.
 35. The method of collecting chips, which consists in the fact that it uses the device according to claim 4 for collecting chips from bone, metal, ceramic or polymer.
 36. The method of collecting chips, which consists in the fact that it uses the device according to claim 4 for collecting chips under the action of a gravity micro-force.
 37. The method of collecting chips, which consists in the fact that it uses the device according to claim 1 or 2, the device being sterile.
 38. The method of collecting chips, which consists in the fact that it uses the device according to claim 4, wherein the device is sterile.
 39. The method of collecting chips, which consists in the fact that it uses the device according to claim 11, the device being sterile.
 40. The method of collecting chips, which consists in the fact that it uses the device according to claim 4, wherein the chip is a chip of bone tissue.
 41. The method according to clause 37, wherein the aseptic transplantation of skeletal tissue from the first site to the second site.
 42. The method according to § 39, characterized in that aseptic transplantation of skeletal tissue from the first site to the second site.
 43. The method of collecting chips, which consists in the fact that it uses the device according to paragraph 24, and the chips are processed.
 44. The method according to item 43, wherein the treatment is washing, grinding, filtering, separating, adding acid, adding a base, adding an encapsulating substance, adding a drug or adding a growth factor.
 45. The method according to p. 41, characterized in that the first section and the second section are in the same subject.
RU98110068/14A 1995-10-30 1996-03-22 System and method for picking of materials RU2169532C2 (en)

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