RU2116068C1 - Модифицирующая удельный вес маркерная частица и способ анализа биологической жидкости - Google Patents

Модифицирующая удельный вес маркерная частица и способ анализа биологической жидкости Download PDF

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Publication number
RU2116068C1
RU2116068C1 RU93004564A RU93004564A RU2116068C1 RU 2116068 C1 RU2116068 C1 RU 2116068C1 RU 93004564 A RU93004564 A RU 93004564A RU 93004564 A RU93004564 A RU 93004564A RU 2116068 C1 RU2116068 C1 RU 2116068C1
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RU
Russia
Prior art keywords
specific gravity
specific
liposomes
vesicle
biological fluid
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Application number
RU93004564A
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English (en)
Russian (ru)
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RU93004564A (ru
Inventor
А.Левин Роберт
С.Вордло Стефен
Родригес Родольфо
Бритц Юдит
Дис. Мерколино Томас
Original Assignee
А.Левин Роберт
С.Вордло Стефен
Бектон Дикинсон энд Компани
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Application filed by А.Левин Роберт, С.Вордло Стефен, Бектон Дикинсон энд Компани filed Critical А.Левин Роберт
Publication of RU93004564A publication Critical patent/RU93004564A/ru
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Publication of RU2116068C1 publication Critical patent/RU2116068C1/ru

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/5375—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by changing the physical or chemical properties of the medium or immunochemicals, e.g. temperature, density, pH, partitioning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/829—Liposomes, e.g. encapsulation

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
RU93004564A 1992-02-25 1993-02-24 Модифицирующая удельный вес маркерная частица и способ анализа биологической жидкости RU2116068C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US84197692A 1992-02-25 1992-02-25
US07/841976 1992-02-25
US07/841,976 1992-02-25

Publications (2)

Publication Number Publication Date
RU93004564A RU93004564A (ru) 1995-05-10
RU2116068C1 true RU2116068C1 (ru) 1998-07-27

Family

ID=25286232

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93004564A RU2116068C1 (ru) 1992-02-25 1993-02-24 Модифицирующая удельный вес маркерная частица и способ анализа биологической жидкости

Country Status (17)

Country Link
US (1) US5593848A (https=)
EP (1) EP0557595B1 (https=)
JP (1) JP2925105B2 (https=)
CN (1) CN1091521A (https=)
AT (1) ATE155889T1 (https=)
AU (1) AU662571B2 (https=)
BR (1) BR9300639A (https=)
CA (1) CA2090282A1 (https=)
DE (1) DE69221118T2 (https=)
DK (1) DK0557595T3 (https=)
ES (1) ES2106121T3 (https=)
FI (1) FI930821L (https=)
GR (1) GR3024970T3 (https=)
MX (1) MX9300965A (https=)
NO (1) NO930649L (https=)
RU (1) RU2116068C1 (https=)
TW (1) TW246716B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2201936C2 (ru) * 1998-06-26 2003-04-10 Пфайзер Продактс Инк. Улучшенный способ получения аддуктов аминов с о-гидроксиальдегидами, являющихся основаниями шиффа, и аддуктный конечный продукт конденсации

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US5342790A (en) * 1992-10-30 1994-08-30 Becton Dickinson And Company Apparatus for indirect fluorescent assay of blood samples
AU4101697A (en) * 1996-11-22 1998-05-28 Robert A. Levine Process for enhancing the aggregation and/or agglutination of erythrocytes prior to centrifugation
US6197523B1 (en) 1997-11-24 2001-03-06 Robert A. Levine Method for the detection, identification, enumeration and confirmation of circulating cancer and/or hematologic progenitor cells in whole blood
AU9233698A (en) * 1997-11-22 1999-06-17 Robert A. Levine Method for the detection, identification, enumeration and confirmation of circulating cancer cells and/or hematologic progenitor cells in whole blood
US6911315B2 (en) * 1997-11-24 2005-06-28 David L. Rimm Method for the detection, identification, enumeration and confirmation of virally infected cells and other epitopically defined cells in whole blood
GB0021303D0 (en) * 2000-08-30 2000-10-18 Medinnova Sf Use
WO2004042019A2 (en) * 2002-10-30 2004-05-21 Pointilliste, Inc. Systems for capture and analysis of biological particles and methods using the systems
JP2007528854A (ja) * 2003-07-09 2007-10-18 カリフォルニア パシフィック メディカル センター 細胞への物質送達の遠隔検出
US7996825B2 (en) * 2003-10-31 2011-08-09 Hewlett-Packard Development Company, L.P. Cross-file inlining by using summaries and global worklist
US20060018911A1 (en) * 2004-01-12 2006-01-26 Dana Ault-Riche Design of therapeutics and therapeutics
US8221985B2 (en) * 2008-04-02 2012-07-17 Abbott Point Of Care, Inc. Self-calibrating gradient dilution in a constituent assay and gradient dilution apparatus performed in a thin film sample
WO2009126505A1 (en) * 2008-04-09 2009-10-15 Abbott Point Of Care, Inc. Method of detecting very low levels of analyte within a thin film fluid sample contained in a thin thickness chamber
FR2965273B1 (fr) * 2010-09-29 2015-07-17 Centre Nat Rech Scient Procede de preparation d'une structure chimique presentant une partition de phases, apte a generer un spectre de fluorescence specifique et ses applications
US9624474B2 (en) 2010-12-01 2017-04-18 Samsung Electronics Co, Ltd. Method of separating target cell in biological sample
CN102788879B (zh) * 2011-05-20 2015-04-01 常州康卫生物技术有限公司 一种生物检测试剂
ES2881977T3 (es) * 2015-05-06 2021-11-30 Seracare Life Sciences Inc Preparaciones liposomales para cribado no invasivo prenatal o de cáncer

Citations (2)

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US4181609A (en) * 1977-12-20 1980-01-01 Levine Robert A Blood constituents testing method
US4591570A (en) * 1983-02-02 1986-05-27 Centocor, Inc. Matrix of antibody-coated spots for determination of antigens

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US3862303A (en) * 1972-02-02 1975-01-21 Atomic Energy Commission Method for rapid detection and identification of serological factors
US4027660A (en) * 1976-04-02 1977-06-07 Wardlaw Stephen C Material layer volume determination
DE3000483A1 (de) * 1979-01-09 1980-07-17 Fuji Photo Film Co Ltd Mikrokapseln fuer immunologische bestimmungen
US4332785A (en) 1980-04-09 1982-06-01 University Patents, Inc. Immunoassay for measurement of reticulocytes, and immunoreactive reagents for use therein
IL64878A (en) * 1982-01-27 1986-01-31 Yissum Res Dev Co Method for detection of and determination of malaria antibodies and malaria antigens in human blood
JPS5984162A (ja) * 1982-11-05 1984-05-15 Toshiba Corp 免疫分析法
JPS6035267A (ja) * 1983-08-05 1985-02-23 Fuji Photo Film Co Ltd 多項目免疫検査法
US5011771A (en) * 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
FR2571498B1 (fr) * 1984-10-04 1988-04-08 Immunotech Sa Procede de separation de cellules utilisant des anticorps et des billes de faible densite
JPS6345563A (ja) * 1986-04-11 1988-02-26 Hitachi Ltd 細胞分析方法
US5001225A (en) * 1986-12-08 1991-03-19 Georgetown University Monoclonal antibodies to a pan-malarial antigen
GB2200448B (en) * 1987-01-23 1991-01-16 Univ London Targetted liposomes and their use in immunoassay
US5017472A (en) * 1987-09-09 1991-05-21 Bankert Richard B Microflotation devices used for immunoassays and cell/molecular fractionation
US4978625A (en) * 1987-10-19 1990-12-18 Becton, Dickinson And Company Fluorescence immunoassay using water insoluble dyes
FR2656233B1 (fr) * 1989-12-22 1993-11-26 Syntex Inc Procede pour separer des constituants dans un melange.
JPH03249561A (ja) * 1990-02-28 1991-11-07 Toshiba Corp 免疫分析試薬

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4181609A (en) * 1977-12-20 1980-01-01 Levine Robert A Blood constituents testing method
US4591570A (en) * 1983-02-02 1986-05-27 Centocor, Inc. Matrix of antibody-coated spots for determination of antigens

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
S zoka F., Papahadjopoulos D., Liposomes: Puparation and characterization, F rom Physicol structure to the therapeutic applycation, Elsevilr (North Hol land Bionudicol Press, 1981, p.69-82. Chard T., Au Introduction to radioim munoassay and related techniques, North - Holland Publishing Company, Amst erdame-New Iork-Oxford, 1978, с.81 (русского текста). *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2201936C2 (ru) * 1998-06-26 2003-04-10 Пфайзер Продактс Инк. Улучшенный способ получения аддуктов аминов с о-гидроксиальдегидами, являющихся основаниями шиффа, и аддуктный конечный продукт конденсации

Also Published As

Publication number Publication date
FI930821A7 (fi) 1993-08-26
EP0557595B1 (en) 1997-07-23
MX9300965A (es) 1994-08-31
BR9300639A (pt) 1993-08-31
AU2983692A (en) 1993-08-26
JPH0821833A (ja) 1996-01-23
ATE155889T1 (de) 1997-08-15
FI930821L (fi) 1993-08-26
NO930649D0 (no) 1993-02-24
TW246716B (https=) 1995-05-01
DK0557595T3 (da) 1997-12-29
ES2106121T3 (es) 1997-11-01
EP0557595A2 (en) 1993-09-01
NO930649L (no) 1993-08-26
DE69221118T2 (de) 1998-02-26
DE69221118D1 (de) 1997-09-04
EP0557595A3 (https=) 1993-11-10
JP2925105B2 (ja) 1999-07-28
FI930821A0 (fi) 1993-02-24
CN1091521A (zh) 1994-08-31
US5593848A (en) 1997-01-14
AU662571B2 (en) 1995-09-07
GR3024970T3 (en) 1998-01-30
CA2090282A1 (en) 1993-08-26

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