RU2063215C1 - Method for treating habitual incomplete pregnancy of endocrinous genesis - Google Patents

Abstract

FIELD: medicine. SUBSTANCE: method involves applying central electroanalgesia at the beginning of treatment with frontomastoidal arrangement of electrodes at 800-1000 Hz pulse frequency, pulse duration of 0.15-0.2 ms, current of 0.2-0.5 mA during 30 to 60 min increasing each following procedure by 10 min. 3 procedures daily are administered during the first half of menstrual cycle and 5 procedures during the second half-cycle for patients beginning the treatment course. Then the procedure is alternatively applied each second day with general hydrogen sulfide baths and vaginal irrigations administered in between. The total course duration is 13 procedures. EFFECT: enhanced effectiveness of treatment course.

Description

 The invention relates to medicine, namely to obstetrics and gynecology.

 Known methods for the treatment of habitual miscarriage of endocrine genesis (1).

 However, these methods basically boil down to prescribing therapeutic factors in the case of a new pregnancy due to the threat of its termination (habitual).

 Closest to the alleged invention relates to a "Method for the prophylactic treatment of women about miscarriage" according to the copyright certificate 1299583 by simultaneous exposure to biologically active points of the skin with vibration and electric shock.

 However, the known method requires special training of a doctor and in addition, the known method is effective only in some cases with hypofunction of the ovaries.

 The purpose of the invention is the creation of optimal conditions for gestation.

 This goal is achieved by the fact that patients undergo hydrogen sulfide balneotherapy (general baths and vaginal irrigation) against the background of central electroanalgesia (CEAN) from the LENAR apparatus.

 The method is as follows.

 From the 2nd day of the patient’s stay at the resort, they undergo CEAN therapy from the LENAR apparatus with frontal mastoidal electrode application. The pulse frequency is 800 1000 Hz, the pulse duration is 0.15 0.2 ms, the current strength is 0.2 0.5 mA, the duration is from 30 to 60 minutes (gradual increase). The first 3 5 procedures are carried out daily, the next every other day with hydrogen sulfide balneotherapy. The number of introductory CEAN procedures: 3 or 5 is determined respectively by the days of the menstrual cycle: for beginners, treatment in the second half of the cycle (after the 15th day) their number is increased to 5; for beginners, treatment from the first half of the cycle is reduced to 3 procedures. Hydrogen sulfide balneotherapy is carried out in the form of vaginal irrigation at a concentration of hydrogen sulfide 100 150 mg / l, at a water temperature of 38 42 degrees. lasting 15 minutes and subsequent hydrogen sulfide baths at a concentration of hydrogen sulfide from 50 to 150 mg / l, at a water temperature of 35 36 degrees. lasting from 6 to 15 minutes In total, 12 13 CEAN procedures and 8 9 balneotherapy procedures per treatment course. In the 1 3 days of menstruation, only vaginal irrigation is canceled, which replaces CEAN or microclysters from hydrogen sulfide water. Considering the chronobiological characteristics of patients, hydrogen sulfide procedures are carried out in the morning from 9 to 12 hours, and CEAN from 12 to 16 hours.

 The combination of CEAN with hydrogen sulfide balneotherapy together with the favorable influence of climatic factors of the resort provides a general healing effect on the body in women with habitual miscarriage of endocrine genesis, most of which experience anxiety and uncertainty about the possibility of cure. The use of CEAN leads to the normalization of neuro-vegetative and immuno-endocrine relationships, which serves as an adequate background for the manifestation of the therapeutic effect of hydrogen sulfide balneotherapy. An important point in the mechanism of action of hydrogen sulfide balneotherapy in these patients is the ability of hydrogen sulfide, as a strong oxidizing agent, to release hormones from a strong bond with the transporting protein, which, together with an increase in their absolute production in endocrine structures, provides the appropriate conditions for the manifestation of their functional activity.

 Examples of specific performance of the method.

 Example 1: Patient L. 37 years old, I. B. N 1633. The engineer. A history of 3 spontaneous miscarriages in terms of 10 to 14 weeks, all ended with curettage of the uterine cavity. There were no births. Menses from 15 years regularly (after 30-60 days) for 4 to 5 days are moderate, painless. Sexual life since 30 years, the first pregnancy at 32.5 years, the last at 35 years. From 32 years old she was treated for infertility, then miscarriage. Received courses of hormone therapy, twice a mud treatment. Upon admission to the resort, the diagnosis was made: Habitual miscarriage of pregnancy of endocrine genesis. Candidiasis vulvovaginitis. Mixed type NDC. Chronic tonsillitis. Astheno-neurosis syndrome.

In the Sochi NIIKif clinic, treatment began on the 15th day of the cycle: The first 5 CEAN procedures from the LENAR apparatus with frontomastoid electrode placement at a pulse frequency of 800-1000 Hz. pulse duration 0.15 0.2 m sec, current 0.2 0.2 mA. The duration of the 1st procedure is 30 minutes, 2nd 40 minutes, 3rd 50 minutes, 4th 60 minutes. From the 6th day of treatment, hydrogen sulfide balneotherapy was prescribed; vaginal irrigation according to Yagunov at a concentration of hydrogen sulfide baths at a concentration of 50 to 150 mg / l, 35 - 36 ^o C, up to 15 minutes Until the end of treatment, baths were performed every other day with CEAN. During treatment, the next menstruation in the patient passed on time (on the 30th day of the cycle), painlessly, moderately. The treatment ended on the 6th day of the next cycle. I received 12 CEEN procedures and 8 common baths, and 7 vaginal irrigation courses. Discharged with improved peripheral blood counts.

Before treatment: er. 3.85x10 ¹² / l, HB 125.4 g / l, ESR 3/9, lake. 3.5, eos. 5% mon 9, s / I 62, lymph. 23
After treatment: 4.83x10 ¹² / L, HB 145.1 g / L, ESR 3/6, Lake. 5.5, eos. 2% mon 10, s / I 58, lymph. 24
During treatment, normalization of the immunogram was also noted:
Before treatment: JgJ 36.0 g / l, A-1.64, M-3.0
After treatment: JgGe 24.6 g / l, A-2.94, M-1.9
Due to the decrease in the complex of circulating immune complexes and increase in secretory immunoglobulin A., the indicators of WG of the small pelvis and REG were improved. According to long-term observations in the next cycle (immediately after treatment), a uterine pregnancy occurred, which ended in childbirth on time. The child develops normally. In subsequent pregnancies, the woman was not interested. Contraception recommended.

 Example 2. Patient M., 27 years old, IB 497. Was admitted to the clinic in the direction of the Rostov Research Institute of Nuclear Medicine and Diagnosis with a diagnosis of Miscarriage of endocrine genesis, ovarian hypofunction with insufficiency of both phases. Endocervicosis. Vaginal candidiasis.

 A history of 2 self-abortions in a period of 6 to 8 weeks. Sexual life since 22 years old, became pregnant in the 1st year, 2nd pregnancy terminated at 26 years old. Surveyed: pipes are passable. Craniography and EEG without features. Diencephalic tests are normal. Uterus according to the probe 4 + 4 cm. Back analysis from the vagina Candida growth.

 The patient was treated with the proposed method, which began on the 3rd day of the cycle. The patient received 3 daily CEAN procedures, then every other day with hydrogen sulfide balneotherapy.

 The patient completed treatment on the 23rd day of the cycle. She received 12 CEAN procedures and 9 balneotherapy procedures (general baths and vaginal irrigation). Discharged in good condition. She became pregnant in the next 2 months after spa treatment by the proposed method. Pregnancy ended in normal term labor (fetal weight 3600, height 54). The health of the child and mother in the following years is good. She was protected from subsequent pregnancies.

 In total, the proposed method treated 28 women 25 38 years old with the usual miscarriage (in the history of 2-5 self-abortions) of endocrine genesis. During the first months after treatment in the clinic of the institute, 9 (32.1%) became pregnant by the proposed method, during the next 6 months, 6 more women, i.e. in the 1st year after spa treatment, uterine pregnancy occurred in 15 (53.57%) women. In 2 of them, the pregnancy ended with self-abortions in the period up to 12 weeks, in the 1st in the period up to 20 weeks. In the following year, everyone again had a pregnancy that ended in an urgent birth. Over the entire observation period (4 years), there were no cases of ectonic pregnancy, and childbirth in another 6 women ended successfully with the birth of a healthy baby.

Thus, as a result of the application of the proposed method of treatment in women with habitual miscarriage of endocrine genesis, 75% of women regained normal reproductive function, including 53.6%
permission came in the first 12 months after spa treatment.

 The proposed method of treatment can be used in practical health care, ready to use, easy to do. Experience and theoretical data on the problem testify in favor of an earlier application of the method in women with 1-2 self-abortions in the anamnesis.

Claims (1)

 A method of treating habitual miscarriage of pregnancy of endocrine genesis, including exposure to a physical factor, characterized in that the treatment begins with central electroanalgesia with frontal-mastoid electrode arrangement at a pulse frequency of 800-1000 Hz, their duration 0.15-0.2 ms, current 0.2-0.5 mA, lasting from 30 to 60 minutes, increasing each subsequent procedure by 10 minutes, while those who started treatment in the first half of the menstrual cycle carry out 3 procedures daily, and in the second half 5 procedures, after why then it alternates every other day with hydrogen sulfide balneotherapy in the form of hydrogen sulfide common baths and vaginal irrigation, for a course of 13 physiotherapy.