RU2017127972A3 - - Google Patents
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- RU2017127972A3 RU2017127972A3 RU2017127972A RU2017127972A RU2017127972A3 RU 2017127972 A3 RU2017127972 A3 RU 2017127972A3 RU 2017127972 A RU2017127972 A RU 2017127972A RU 2017127972 A RU2017127972 A RU 2017127972A RU 2017127972 A3 RU2017127972 A3 RU 2017127972A3
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/005—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1058—Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
- C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Ecology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562120312P | 2015-02-24 | 2015-02-24 | |
| US62/120,312 | 2015-02-24 | ||
| US201562249907P | 2015-11-02 | 2015-11-02 | |
| US62/249,907 | 2015-11-02 | ||
| PCT/US2016/019242 WO2016138071A1 (en) | 2015-02-24 | 2016-02-24 | Conditionally active biological proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2017127972A RU2017127972A (ru) | 2019-03-25 |
| RU2017127972A3 true RU2017127972A3 (ru) | 2019-08-09 |
| RU2733658C2 RU2733658C2 (ru) | 2020-10-06 |
Family
ID=56789902
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2017127972A RU2733658C2 (ru) | 2015-02-24 | 2016-02-24 | Условно активные биологические белки |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US10563194B2 (ru) |
| EP (1) | EP3262217A4 (ru) |
| JP (3) | JP7025214B2 (ru) |
| KR (3) | KR102286801B1 (ru) |
| CN (1) | CN107580603A (ru) |
| AU (3) | AU2016222830B2 (ru) |
| CA (2) | CA2977687C (ru) |
| MX (2) | MX2017010795A (ru) |
| RU (1) | RU2733658C2 (ru) |
| SG (2) | SG11201705988UA (ru) |
| WO (1) | WO2016138071A1 (ru) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ721309A (en) | 2013-12-17 | 2019-11-29 | Genentech Inc | Anti-cd3 antibodies and methods of use |
| DK3143138T3 (da) * | 2014-05-13 | 2022-04-25 | Bioatla Inc | Betinget aktive biologiske proteiner |
| EP3186284B1 (en) | 2014-08-28 | 2022-04-06 | BioAtla, Inc. | Conditionally active chimeric antigen receptors for modified t-cells |
| KR20230044567A (ko) * | 2016-05-13 | 2023-04-04 | 바이오아트라, 인코퍼레이티드 | 항 ror2 항체, 항체 단편 및 이의 면역접합체와 이것들의 용도 |
| AU2017320874B2 (en) * | 2016-08-31 | 2024-03-07 | Bioatla, Llc | Conditionally active polypeptides and methods of generating them |
| KR20190074300A (ko) | 2016-11-15 | 2019-06-27 | 제넨테크, 인크. | 항-cd20/항-cd3 이중특이적 항체에 의한 치료를 위한 투약 |
| CN110382543B (zh) * | 2017-01-03 | 2023-12-26 | 生物蛋白有限公司 | 用于治疗衰老细胞的蛋白治疗剂 |
| WO2018189611A1 (en) * | 2017-04-12 | 2018-10-18 | Pfizer Inc. | Antibodies having conditional affinity and methods of use thereof |
| MX2020013243A (es) | 2018-06-05 | 2021-05-12 | Bioatla Inc | Anticuerpos anti-il-22, fragmentos de anticuerpo, sus inmunoconjugados y usos de los mismos. |
| CA3103414A1 (en) * | 2018-06-14 | 2019-12-19 | Bioatla, Inc. | Multi-specific antibody constructs |
| CN111505288B (zh) * | 2020-05-15 | 2022-03-01 | 重庆医科大学 | 一种新的抑郁症生物标志物及其应用 |
| CN114259460B (zh) * | 2020-09-16 | 2024-03-15 | 苏州大学 | 基于免疫佐剂的水凝胶组合物及其应用 |
| CN118076632A (zh) * | 2021-10-19 | 2024-05-24 | 生物蛋白有限公司 | 用于神经退化性疾病的条件活性蛋白质 |
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-
2016
- 2016-02-24 CA CA2977687A patent/CA2977687C/en active Active
- 2016-02-24 KR KR1020177023331A patent/KR102286801B1/ko active IP Right Grant
- 2016-02-24 AU AU2016222830A patent/AU2016222830B2/en active Active
- 2016-02-24 WO PCT/US2016/019242 patent/WO2016138071A1/en active Application Filing
- 2016-02-24 CN CN201680012058.5A patent/CN107580603A/zh active Pending
- 2016-02-24 CA CA3225013A patent/CA3225013A1/en active Pending
- 2016-02-24 US US15/546,883 patent/US10563194B2/en active Active
- 2016-02-24 MX MX2017010795A patent/MX2017010795A/es active IP Right Grant
- 2016-02-24 JP JP2017562970A patent/JP7025214B2/ja active Active
- 2016-02-24 RU RU2017127972A patent/RU2733658C2/ru active
- 2016-02-24 SG SG11201705988UA patent/SG11201705988UA/en unknown
- 2016-02-24 KR KR1020237022948A patent/KR20230109773A/ko not_active Application Discontinuation
- 2016-02-24 SG SG10202108814VA patent/SG10202108814VA/en unknown
- 2016-02-24 EP EP16756238.8A patent/EP3262217A4/en active Pending
- 2016-02-24 KR KR1020217024058A patent/KR20210096326A/ko not_active IP Right Cessation
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2017
- 2017-08-22 MX MX2020011052A patent/MX2020011052A/es unknown
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2020
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2021
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2022
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2023
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2024
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|---|---|
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| CA3225013A1 (en) | 2016-09-01 |
| US20190024078A1 (en) | 2019-01-24 |
| EP3262217A4 (en) | 2018-07-18 |
| RU2733658C2 (ru) | 2020-10-06 |
| AU2024203877A1 (en) | 2024-06-27 |
| US20220127595A1 (en) | 2022-04-28 |
| JP2022031720A (ja) | 2022-02-22 |
| SG10202108814VA (en) | 2021-09-29 |
| EP3262217A1 (en) | 2018-01-03 |
| CN107580603A (zh) | 2018-01-12 |
| JP2023182651A (ja) | 2023-12-26 |
| CA2977687A1 (en) | 2016-09-01 |
| MX2017010795A (es) | 2018-04-11 |
| AU2016222830A1 (en) | 2017-08-10 |
| AU2021203506A1 (en) | 2021-06-17 |
| JP7025214B2 (ja) | 2022-02-24 |
| AU2016222830B2 (en) | 2021-02-25 |
| US20200199578A1 (en) | 2020-06-25 |
| JP2018513206A (ja) | 2018-05-24 |
| RU2017127972A (ru) | 2019-03-25 |
| KR20170117089A (ko) | 2017-10-20 |
| CA2977687C (en) | 2024-02-13 |
| AU2021203506B2 (en) | 2024-06-27 |
| KR20230109773A (ko) | 2023-07-20 |
| KR20210096326A (ko) | 2021-08-04 |
| WO2016138071A1 (en) | 2016-09-01 |
| SG11201705988UA (en) | 2017-08-30 |
| KR102286801B1 (ko) | 2021-08-09 |
| MX2020011052A (es) | 2020-11-06 |
| US11254932B2 (en) | 2022-02-22 |