RU2008103370A - Маркеры фиброза - Google Patents
Маркеры фиброза Download PDFInfo
- Publication number
- RU2008103370A RU2008103370A RU2008103370/15A RU2008103370A RU2008103370A RU 2008103370 A RU2008103370 A RU 2008103370A RU 2008103370/15 A RU2008103370/15 A RU 2008103370/15A RU 2008103370 A RU2008103370 A RU 2008103370A RU 2008103370 A RU2008103370 A RU 2008103370A
- Authority
- RU
- Russia
- Prior art keywords
- use according
- markers
- kit
- combination
- biological sample
- Prior art date
Links
- 206010016654 Fibrosis Diseases 0.000 title claims abstract 5
- 230000004761 fibrosis Effects 0.000 title claims abstract 5
- 239000012472 biological sample Substances 0.000 claims abstract 8
- 230000003176 fibrotic effect Effects 0.000 claims abstract 8
- 239000000523 sample Substances 0.000 claims abstract 6
- 101150031810 AGP1 gene Proteins 0.000 claims abstract 5
- 102100022463 Alpha-1-acid glycoprotein 1 Human genes 0.000 claims abstract 5
- 101100165241 Arabidopsis thaliana BCP1 gene Proteins 0.000 claims abstract 5
- 101100244969 Arabidopsis thaliana PRL1 gene Proteins 0.000 claims abstract 5
- 102100039558 Galectin-3 Human genes 0.000 claims abstract 5
- 101100454448 Homo sapiens LGALS3 gene Proteins 0.000 claims abstract 5
- 101150051246 MAC2 gene Proteins 0.000 claims abstract 5
- 101150110809 ORM1 gene Proteins 0.000 claims abstract 5
- 102000018614 Uromodulin Human genes 0.000 claims abstract 5
- 108010027007 Uromodulin Proteins 0.000 claims abstract 5
- 102000005572 Cathepsin A Human genes 0.000 claims abstract 4
- 108010059081 Cathepsin A Proteins 0.000 claims abstract 4
- 238000000034 method Methods 0.000 claims abstract 4
- 238000003018 immunoassay Methods 0.000 claims abstract 3
- 210000004185 liver Anatomy 0.000 claims abstract 3
- 239000003550 marker Substances 0.000 claims abstract 3
- 210000002700 urine Anatomy 0.000 claims abstract 3
- 241000124008 Mammalia Species 0.000 claims abstract 2
- 238000005481 NMR spectroscopy Methods 0.000 claims abstract 2
- 239000008280 blood Substances 0.000 claims abstract 2
- 210000004369 blood Anatomy 0.000 claims abstract 2
- 210000001185 bone marrow Anatomy 0.000 claims abstract 2
- 238000004587 chromatography analysis Methods 0.000 claims abstract 2
- 208000019425 cirrhosis of liver Diseases 0.000 claims abstract 2
- 238000004737 colorimetric analysis Methods 0.000 claims abstract 2
- 238000001962 electrophoresis Methods 0.000 claims abstract 2
- 210000002216 heart Anatomy 0.000 claims abstract 2
- 238000000338 in vitro Methods 0.000 claims abstract 2
- 210000003734 kidney Anatomy 0.000 claims abstract 2
- 210000004072 lung Anatomy 0.000 claims abstract 2
- 210000000056 organ Anatomy 0.000 claims abstract 2
- 210000000496 pancreas Anatomy 0.000 claims abstract 2
- 210000002381 plasma Anatomy 0.000 claims abstract 2
- 238000002798 spectrophotometry method Methods 0.000 claims abstract 2
- 238000002965 ELISA Methods 0.000 claims 2
- 239000000872 buffer Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 238000003317 immunochromatography Methods 0.000 claims 1
- 230000000155 isotopic effect Effects 0.000 claims 1
- 102000005600 Cathepsins Human genes 0.000 abstract 1
- 108010084457 Cathepsins Proteins 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/08—Hepato-biliairy disorders other than hepatitis
- G01N2800/085—Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200501611A ES2288358B1 (es) | 2005-07-01 | 2005-07-01 | Marcadores de fibrosis. |
ESP200501611 | 2005-07-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
RU2008103370A true RU2008103370A (ru) | 2009-08-10 |
Family
ID=37604101
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2008103370/15A RU2008103370A (ru) | 2005-07-01 | 2006-06-22 | Маркеры фиброза |
Country Status (11)
Country | Link |
---|---|
US (1) | US20090117591A1 (pt) |
EP (1) | EP1918715A1 (pt) |
JP (1) | JP2009500597A (pt) |
CN (1) | CN101356439A (pt) |
AU (1) | AU2006264946A1 (pt) |
BR (1) | BRPI0613169A2 (pt) |
CA (1) | CA2613833A1 (pt) |
ES (1) | ES2288358B1 (pt) |
MX (1) | MX2008000059A (pt) |
RU (1) | RU2008103370A (pt) |
WO (1) | WO2007003670A1 (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8426142B2 (en) | 2008-06-02 | 2013-04-23 | Eisai R&D Management Co., Ltd. | IgA nephropathy testing method and test kit |
WO2010079253A2 (es) | 2009-01-09 | 2010-07-15 | Proyecto De Biomedicina Cima, S.L. | Biomarcadores para el diagnóstico de fibrosis |
JP5887141B2 (ja) * | 2009-02-26 | 2016-03-16 | ユニバーシティ ダンガース | 肝線維症または肝硬変の向上した診断方法 |
JP5031928B2 (ja) * | 2009-07-14 | 2012-09-26 | 独立行政法人産業技術総合研究所 | 糖タンパク質の測定方法、肝疾患の検査方法、糖タンパク質定量用試薬および肝疾患病態指標糖鎖マーカー糖タンパク質 |
EP2950098A1 (en) | 2009-07-14 | 2015-12-02 | National Institute of Advanced Industrial Science and Technology | Glycan markers as measure of disease state of hepatic diseases |
EP2630499A2 (en) * | 2010-10-21 | 2013-08-28 | Vertex Pharmaceuticals Incorporated | Biomarkers for hcv infected patients |
CA2831827A1 (en) | 2011-04-05 | 2012-10-11 | Academisch Ziekenhuis Leiden H.O.D.N. Lumc | Compounds and methods for altering activin receptor-like kinase signalling |
CN102645540A (zh) * | 2012-04-01 | 2012-08-22 | 安徽四正医药科技有限公司 | 一种用于诊断肝纤维化和早期肝硬化的血液标志物 |
CN105980861B (zh) * | 2013-12-10 | 2018-08-24 | 加利福尼亚大学董事会 | 肝病的区分性诊断 |
WO2016054155A1 (en) * | 2014-09-30 | 2016-04-07 | Primegen Biotech, Llc. | Treatment of fibrosis using deep tissue heating and stem cell therapy |
JP6799226B2 (ja) * | 2015-07-24 | 2020-12-16 | 公立大学法人名古屋市立大学 | 骨髄線維症の状態の診断を補助する方法、予後の予測を補助する方法、及び治療効果のモニター方法、並びにそれらの方法に用いるマーカー及び装置 |
CN114280300B (zh) * | 2021-12-28 | 2023-04-25 | 四川大学华西医院 | 尿液蛋白在诊断代谢性肝病中的应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4894442A (en) * | 1985-04-12 | 1990-01-16 | Kuraray Co., Ltd. | Monoclonal antibodies that bind to alpha-acid glycoprotein |
DE3832432A1 (de) * | 1988-09-23 | 1990-03-29 | Max Planck Gesellschaft | Verfahren zum nachweis der funktionsfaehigkeit der nierentubuli |
US5604105B1 (en) * | 1990-10-12 | 1999-08-24 | Spectral Diagnostics Inc | Method and device for diagnosingand distinguishing chest pain in early onset thereof |
AU673810B2 (en) * | 1991-10-16 | 1996-11-28 | Chiron Corporation | Secreted Mac-2-binding glycoprotein |
US6242246B1 (en) * | 1997-12-15 | 2001-06-05 | Somalogic, Inc. | Nucleic acid ligand diagnostic Biochip |
AU2002305394A1 (en) * | 2001-05-04 | 2002-11-18 | Biosite, Inc. | Diagnostic markers of acute coronary syndromes and methods of use thereof |
-
2005
- 2005-07-01 ES ES200501611A patent/ES2288358B1/es not_active Expired - Fee Related
-
2006
- 2006-06-22 BR BRPI0613169-7A patent/BRPI0613169A2/pt not_active IP Right Cessation
- 2006-06-22 RU RU2008103370/15A patent/RU2008103370A/ru not_active Application Discontinuation
- 2006-06-22 CN CNA2006800313387A patent/CN101356439A/zh active Pending
- 2006-06-22 CA CA002613833A patent/CA2613833A1/en not_active Abandoned
- 2006-06-22 AU AU2006264946A patent/AU2006264946A1/en not_active Abandoned
- 2006-06-22 MX MX2008000059A patent/MX2008000059A/es not_active Application Discontinuation
- 2006-06-22 JP JP2008518876A patent/JP2009500597A/ja not_active Withdrawn
- 2006-06-22 WO PCT/ES2006/000367 patent/WO2007003670A1/es active Application Filing
- 2006-06-22 EP EP06794042A patent/EP1918715A1/en not_active Withdrawn
- 2006-06-22 US US11/988,092 patent/US20090117591A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2613833A1 (en) | 2007-01-11 |
US20090117591A1 (en) | 2009-05-07 |
BRPI0613169A2 (pt) | 2010-12-21 |
WO2007003670A1 (es) | 2007-01-11 |
AU2006264946A1 (en) | 2007-01-11 |
MX2008000059A (es) | 2008-03-19 |
CN101356439A (zh) | 2009-01-28 |
ES2288358A1 (es) | 2008-01-01 |
ES2288358B1 (es) | 2008-11-16 |
WO2007003670A8 (es) | 2008-01-17 |
EP1918715A1 (en) | 2008-05-07 |
JP2009500597A (ja) | 2009-01-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20100623 |