RU2001113688A - Use of paclitaxel stabilized by albumin, for the manufacture of a medicament for the treatment of solid tumors and the drug obtained in this manner - Google Patents

Use of paclitaxel stabilized by albumin, for the manufacture of a medicament for the treatment of solid tumors and the drug obtained in this manner

Info

Publication number
RU2001113688A
RU2001113688A RU2001113688/14A RU2001113688A RU2001113688A RU 2001113688 A RU2001113688 A RU 2001113688A RU 2001113688/14 A RU2001113688/14 A RU 2001113688/14A RU 2001113688 A RU2001113688 A RU 2001113688A RU 2001113688 A RU2001113688 A RU 2001113688A
Authority
RU
Russia
Prior art keywords
medicament
microparticles
albumin
treatment
use
Prior art date
Application number
RU2001113688/14A
Other languages
Russian (ru)
Other versions
RU2270003C2 (en
Inventor
Марко ФАЛЬЧЬЯНИ
Original Assignee
Акс Добфар С.П.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ITMI20001107 priority Critical patent/ITMI20001107A1/en
Priority to ITMI2000A001107 priority
Application filed by Акс Добфар С.П.А. filed Critical Акс Добфар С.П.А.
Publication of RU2001113688A publication Critical patent/RU2001113688A/en
Application granted granted Critical
Publication of RU2270003C2 publication Critical patent/RU2270003C2/en

Links

Claims (4)

1. Применение микрочастиц паклитаксела, стабилизированных альбумином, для изготовления лекарственного средства для лечения солидных опухолей, чувствительных к паклитакселу, в частности, плоскоклеточных карцином; 1. Use of microparticles of Paclitaxel stabilized with albumin for the manufacture of a medicament for the treatment of solid tumors sensitive to Paclitaxel, in particular, squamous cell carcinomas; указанное лекарственное средство включает дисперсию указанных микрочастиц в физиологическом растворе, в котором микрочастицы находятся в концентрации от 2 до 8 мг/мл указанного раствора. said medicament comprises a dispersion of said microparticles in a physiological solution in which the microparticles are in a concentration of from 2 to 8 mg / ml of said solution.
2. Применение микрочастиц по п. 1, отличающееся тем, что концентрация указанных микрочастиц в дисперсии составляет от 3 до 7,5 мг/мл физиологического раствора. 2. Use of microparticles according to Claim. 1, characterized in that the concentration of said microparticles in the dispersion is between 3 and 7.5 mg / ml of saline.
3. Лекарственное средство для лечения солидных опухолей, чувствительных к паклитакселу, отличающееся тем, что оно включает дисперсию микрочастиц паклитаксела, стабилизированных альбумином, в физиологическом растворе, в котором концентрация микрочастиц составляет от 2 до 8 мг/мл указанного раствора. 3. A medicament for the treatment of solid tumors sensitive to Paclitaxel, characterized in that it comprises a dispersion of microparticles of Paclitaxel stabilized with albumin in a physiological solution in which the concentration of the microparticles is between 2 and 8 mg / ml of said solution.
4. Лекарственное средство по п. 3, отличающееся тем, что концентрация микрочастиц составляет от 3 до 7,5 мг/мл раствора. 4. A medicament according to claim. 3, characterized in that the concentration of the microparticles is between 3 and 7.5 mg / ml of solution.
RU2001113688/15A 2000-05-18 2001-05-17 Paclitaxel-base medicinal agent stabilized with albumin for treatment of solid tumor RU2270003C2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ITMI20001107 ITMI20001107A1 (en) 2000-05-18 2000-05-18 Method for the treatment of tumors by solici albumin microparticles incorporating Paclitaxel
ITMI2000A001107 2000-05-18

Publications (2)

Publication Number Publication Date
RU2001113688A true RU2001113688A (en) 2003-03-10
RU2270003C2 RU2270003C2 (en) 2006-02-20

Family

ID=11445079

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2001113688/15A RU2270003C2 (en) 2000-05-18 2001-05-17 Paclitaxel-base medicinal agent stabilized with albumin for treatment of solid tumor

Country Status (23)

Country Link
US (1) US6652884B2 (en)
EP (1) EP1155692B1 (en)
JP (1) JP2001354559A (en)
KR (1) KR20080091747A (en)
CN (1) CN1198609C (en)
AT (1) AT267594T (en)
AU (1) AU781517B2 (en)
BR (1) BR0102040A (en)
CA (1) CA2345482A1 (en)
DE (1) DE60103453T2 (en)
DK (1) DK1155692T3 (en)
ES (1) ES2221874T3 (en)
HK (1) HK1040368A1 (en)
HU (1) HU229909B1 (en)
IL (1) IL142674D0 (en)
IT (1) ITMI20001107A1 (en)
MX (1) MXPA01004980A (en)
NO (1) NO330511B1 (en)
NZ (1) NZ511201A (en)
PT (1) PT1155692E (en)
RU (1) RU2270003C2 (en)
TR (1) TR200101353A3 (en)
ZA (1) ZA200103755B (en)

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US8735394B2 (en) 2005-02-18 2014-05-27 Abraxis Bioscience, Llc Combinations and modes of administration of therapeutic agents and combination therapy
US8034765B2 (en) 2005-08-31 2011-10-11 Abraxis Bioscience, Llc Compositions and methods for preparation of poorly water soluble drugs with increased stability
EP3311805A1 (en) 2005-08-31 2018-04-25 Abraxis BioScience, LLC Compositions comprising poorly water soluble pharmaceutical agents and antimicrobial agents
AU2006324872B2 (en) * 2005-10-21 2012-03-08 Panacea Biotec Limited Pharmaceutical composition comprising at least one anticancer drug and at least one polymer
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CN101605535A (en) 2006-12-14 2009-12-16 阿布拉科斯生物科学有限公司 Breast cancer therapy based on hormone receptor status with nanoparticles comprising taxane
PL2481409T3 (en) 2007-03-07 2018-11-30 Abraxis Bioscience, Llc Nanoparticle comprising rapamycin and albumin as anticancer agent
WO2008137148A2 (en) * 2007-05-03 2008-11-13 Abraxis Bioscience, Llc Methods and compositions for treating pulmonary hypertension
AU2008260447B2 (en) 2007-06-01 2013-10-10 Abraxis Bioscience, Llc Methods and compositions for treating recurrent cancer
AU2009234127B2 (en) * 2008-04-10 2015-04-30 Abraxis Bioscience, Llc Compositions of hydrophobic taxane derivatives and uses thereof
KR101090505B1 (en) * 2008-12-30 2011-12-06 최은아 Composition comprising egg white-chalcanthite for preventing or treating cancer
US20100297243A1 (en) 2009-04-15 2010-11-25 Desai Neil P Prion free nanoparticle compositions and methods of making thereof
CN104784121A (en) 2010-03-26 2015-07-22 阿布拉科斯生物科学有限公司 Methods of treatment of hepatocellular carcinoma
BR112012024442A2 (en) 2010-03-29 2017-03-21 Abraxis Bioscience Llc cancer treatment methods
KR20130088116A (en) 2010-06-04 2013-08-07 아브락시스 바이오사이언스, 엘엘씨 Methods of treatment of pancreatic cancer
KR20190043632A (en) 2011-04-28 2019-04-26 아브락시스 바이오사이언스, 엘엘씨 Intravascular delivery of nanoparticle compositions and uses thereof
DK2790675T3 (en) 2011-12-14 2019-09-09 Abraxis Bioscience Llc Application of polymer excipients for freezing dry or freezing of particles
US9149455B2 (en) 2012-11-09 2015-10-06 Abraxis Bioscience, Llc Methods of treating melanoma
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EP1100494A1 (en) 1998-07-30 2001-05-23 Novopharm Biotech, Inc. Pharmaceutically composition comprising an aqueous solution of paclitaxel and albumin

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