PT98640A - Processo para a peparacao de tetrahidrobenz-{cd}indoles 6-substituidos - Google Patents
Processo para a peparacao de tetrahidrobenz-{cd}indoles 6-substituidosInfo
- Publication number
- PT98640A PT98640A PT98640A PT9864091A PT98640A PT 98640 A PT98640 A PT 98640A PT 98640 A PT98640 A PT 98640A PT 9864091 A PT9864091 A PT 9864091A PT 98640 A PT98640 A PT 98640A
- Authority
- PT
- Portugal
- Prior art keywords
- indoles
- peparation
- tetrahydrobenz
- substituted
- substituted tetrahydrobenz
- Prior art date
Links
- 150000002475 indoles Chemical class 0.000 title 1
- -1 4-amino-6-substituted-tetrahydrobenz [cd] indoles Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Otolaryngology (AREA)
- Urology & Nephrology (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56799090A | 1990-08-15 | 1990-08-15 | |
US07/725,175 US5229409A (en) | 1990-08-15 | 1991-07-03 | 6-substituted-tetrahydrobenz[cd]indoles |
Publications (2)
Publication Number | Publication Date |
---|---|
PT98640A true PT98640A (pt) | 1992-06-30 |
PT98640B PT98640B (pt) | 1999-01-29 |
Family
ID=27074632
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT98640A PT98640B (pt) | 1990-08-15 | 1991-08-12 | Processo para a peparacao de tetrahidrobenz-{cd}indoles 6-substituidos |
Country Status (25)
Country | Link |
---|---|
US (1) | US5229409A (pt) |
EP (1) | EP0471576B1 (pt) |
JP (1) | JP3034085B2 (pt) |
KR (1) | KR100221159B1 (pt) |
CN (1) | CN1031999C (pt) |
AT (1) | ATE234285T1 (pt) |
AU (1) | AU648575B2 (pt) |
BR (1) | BR9103481A (pt) |
CA (1) | CA2049212C (pt) |
CZ (1) | CZ280605B6 (pt) |
DE (1) | DE69133212T2 (pt) |
DK (1) | DK0471576T3 (pt) |
ES (1) | ES2194007T3 (pt) |
FI (1) | FI102677B1 (pt) |
HU (1) | HU220757B1 (pt) |
IE (1) | IE912878A1 (pt) |
IL (1) | IL99148A (pt) |
MX (1) | MX9100646A (pt) |
MY (1) | MY106764A (pt) |
NO (1) | NO176020C (pt) |
NZ (1) | NZ239333A (pt) |
PT (1) | PT98640B (pt) |
RU (1) | RU2073672C1 (pt) |
TW (1) | TW197422B (pt) |
YU (1) | YU48058B (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5204340A (en) * | 1989-04-11 | 1993-04-20 | Eli Lilly And Company | Tetrahydrobenz(c,d)indole serotonin agonists |
TW219933B (pt) * | 1990-02-26 | 1994-02-01 | Lilly Co Eli | |
US5340838A (en) * | 1990-05-04 | 1994-08-23 | Eli Lilly And Company | Method of inhibiting gastric acid secretion with 2-phenylcyclopropylamines |
US5089517A (en) * | 1990-08-03 | 1992-02-18 | The Board Of Trustees Of The Leland Stanford Junior University | Neuroprotection by indolactam v and derivatives thereof |
US5229410A (en) * | 1990-08-15 | 1993-07-20 | Eli Lilly And Company | 6-substituted-hexahydrobenz[cd]indoles |
NZ314570A (en) * | 1993-06-10 | 2000-11-24 | Lilly Co Eli | Treatment of emesis using tetrahydrobenz[cd]indole-6-carboxamides |
US5385928A (en) * | 1994-05-18 | 1995-01-31 | Eli Lilly And Company | Tetrahydrobenz [CD] indazoles, compositions and use |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE517732C (de) * | 1927-10-27 | 1931-02-09 | Then Rudolf | Faerbekufe mit einem drehbaren, trommelartigen Rahmen fuer die auf aus-wechselbaren Faerbestoecken aufgehaengten Waren, insbesondere Struempfe |
US3194811A (en) * | 1963-09-05 | 1965-07-13 | Merck & Co Inc | Aroyl-benzindolyl acids |
BE755270A (fr) * | 1969-08-27 | 1971-02-25 | Sandoz Sa | Nouveaux derives du benzo(cd)indole, leur preparation et medicaments contenant ces derives |
BE757879A (fr) * | 1969-10-24 | 1971-04-22 | Sandoz Sa | Derives du benzo(cd)indole, leur preparation et medicaments contenant ces derives |
FI206974A (pt) * | 1973-07-16 | 1975-01-17 | Sandoz Ag | |
US4110339A (en) * | 1977-11-25 | 1978-08-29 | Eli Lilly And Company | 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole |
ZA795239B (en) * | 1978-10-12 | 1980-11-26 | Glaxo Group Ltd | Heterocyclic compounds |
US4282240A (en) * | 1979-11-23 | 1981-08-04 | Merck & Co., Inc. | Amino substituted tetrahydrobenzindoles |
FR2510111A1 (fr) * | 1981-07-24 | 1983-01-28 | Roussel Uclaf | Nouveaux derives du piperidin-3-yl indole, leurs sels, leur procede de preparation, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant |
FR2522658A1 (fr) * | 1982-03-05 | 1983-09-09 | Roussel Uclaf | Application a titre de medicaments de derives du trans 4-amino benz (c,d) indol-5-ol ainsi que de leurs sels, compositions les renfermant, nouveaux derives et leur procede de preparation |
DE3346573A1 (de) * | 1983-12-23 | 1985-07-04 | Troponwerke GmbH & Co KG, 5000 Köln | 1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung |
IL74222A (en) * | 1984-02-06 | 1988-07-31 | Lilly Co Eli | 6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them |
US4983622A (en) * | 1984-02-06 | 1991-01-08 | Eli Lilly And Company | 6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles |
US4576959A (en) * | 1984-02-06 | 1986-03-18 | Eli Lilly And Company | 6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles |
CA1266482A1 (en) * | 1984-05-24 | 1990-03-06 | Carl Kaiser | 6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines |
DE3525564A1 (de) * | 1985-07-15 | 1987-02-05 | Schering Ag | Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel |
US4745126A (en) * | 1987-03-12 | 1988-05-17 | Eli Lilly And Company | Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides |
DE3809155A1 (de) * | 1988-03-18 | 1989-09-28 | Bayer Ag | 1,3,4,5-tetrahydrobenz-(c,d)-indole |
US5204340A (en) * | 1989-04-11 | 1993-04-20 | Eli Lilly And Company | Tetrahydrobenz(c,d)indole serotonin agonists |
JPH07103105B2 (ja) * | 1989-05-12 | 1995-11-08 | 杏林製薬株式会社 | インドール誘導体及びその製造方法 |
US5039820A (en) * | 1990-02-26 | 1991-08-13 | Eli Lilly And Company | 4-amino-6-iodo-hexahydrobenz(cd)indoles |
US5096908A (en) * | 1990-05-04 | 1992-03-17 | Eli Lilly And Company | Method of inhibiting gastric acid secretion |
-
1991
- 1991-07-03 US US07/725,175 patent/US5229409A/en not_active Expired - Lifetime
- 1991-08-09 NZ NZ239333A patent/NZ239333A/xx not_active IP Right Cessation
- 1991-08-09 IL IL9914891A patent/IL99148A/en not_active IP Right Cessation
- 1991-08-12 PT PT98640A patent/PT98640B/pt not_active IP Right Cessation
- 1991-08-12 CZ CS912494A patent/CZ280605B6/cs not_active IP Right Cessation
- 1991-08-13 MY MYPI91001471A patent/MY106764A/en unknown
- 1991-08-13 MX MX9100646A patent/MX9100646A/es not_active IP Right Cessation
- 1991-08-13 FI FI913835A patent/FI102677B1/fi not_active IP Right Cessation
- 1991-08-13 TW TW080106390A patent/TW197422B/zh active
- 1991-08-13 KR KR1019910013967A patent/KR100221159B1/ko not_active IP Right Cessation
- 1991-08-13 AU AU82406/91A patent/AU648575B2/en not_active Ceased
- 1991-08-13 NO NO913159A patent/NO176020C/no unknown
- 1991-08-14 EP EP91307531A patent/EP0471576B1/en not_active Expired - Lifetime
- 1991-08-14 YU YU140491A patent/YU48058B/sh unknown
- 1991-08-14 ES ES91307531T patent/ES2194007T3/es not_active Expired - Lifetime
- 1991-08-14 JP JP3204237A patent/JP3034085B2/ja not_active Expired - Fee Related
- 1991-08-14 IE IE287891A patent/IE912878A1/en not_active Application Discontinuation
- 1991-08-14 CN CN91105624A patent/CN1031999C/zh not_active Expired - Fee Related
- 1991-08-14 DK DK91307531T patent/DK0471576T3/da active
- 1991-08-14 AT AT91307531T patent/ATE234285T1/de not_active IP Right Cessation
- 1991-08-14 HU HU9102706A patent/HU220757B1/hu not_active IP Right Cessation
- 1991-08-14 BR BR919103481A patent/BR9103481A/pt not_active Application Discontinuation
- 1991-08-14 CA CA002049212A patent/CA2049212C/en not_active Expired - Fee Related
- 1991-08-14 DE DE69133212T patent/DE69133212T2/de not_active Expired - Fee Related
-
1992
- 1992-09-30 RU SU925052704A patent/RU2073672C1/ru active
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB1A | Laying open of patent application |
Effective date: 19920225 |
|
FG3A | Patent granted, date of granting |
Effective date: 19981020 |
|
MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20070420 |