PT670898E - Polipeptidos de multiplas mutacoes de interleucina-3 (il-3) - Google Patents

Polipeptidos de multiplas mutacoes de interleucina-3 (il-3)

Info

Publication number
PT670898E
PT670898E PT94902293T PT94902293T PT670898E PT 670898 E PT670898 E PT 670898E PT 94902293 T PT94902293 T PT 94902293T PT 94902293 T PT94902293 T PT 94902293T PT 670898 E PT670898 E PT 670898E
Authority
PT
Portugal
Prior art keywords
hil
muteins
amino acid
relates
present
Prior art date
Application number
PT94902293T
Other languages
English (en)
Inventor
Mark Allen Abrams
Sarah Ruth Braford-Goldberg
Maire Helena Caparon
Alan Michael Easton
Barbara Kure Klein
John Patrick Mckearn
Peter O Olins
John Warren Thomas
S Christopher Bauer
Kumman Paik
Joseph O Polazzi
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of PT670898E publication Critical patent/PT670898E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5403—IL-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/141—Interleukin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT94902293T 1992-11-24 1993-11-22 Polipeptidos de multiplas mutacoes de interleucina-3 (il-3) PT670898E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US98104492A 1992-11-24 1992-11-24

Publications (1)

Publication Number Publication Date
PT670898E true PT670898E (pt) 2004-02-27

Family

ID=25528061

Family Applications (2)

Application Number Title Priority Date Filing Date
PT94901584T PT672145E (pt) 1992-11-24 1993-11-22 Polipeptideos de interleucina-3(il-3) com multiplas mutacoes
PT94902293T PT670898E (pt) 1992-11-24 1993-11-22 Polipeptidos de multiplas mutacoes de interleucina-3 (il-3)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT94901584T PT672145E (pt) 1992-11-24 1993-11-22 Polipeptideos de interleucina-3(il-3) com multiplas mutacoes

Country Status (12)

Country Link
US (11) US5604116A (pt)
EP (4) EP0670898B1 (pt)
JP (3) JPH08503706A (pt)
KR (1) KR100332139B1 (pt)
AT (2) ATE251669T1 (pt)
AU (3) AU690088B2 (pt)
CA (2) CA2150117A1 (pt)
DE (2) DE69332908T2 (pt)
DK (2) DK0672145T3 (pt)
ES (2) ES2211875T3 (pt)
PT (2) PT672145E (pt)
WO (2) WO1994012639A2 (pt)

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US5501962A (en) * 1993-06-21 1996-03-26 G. D. Searle & Co. Interleuken-3 (IL-3) human/murine hybrid polypeptides and recombinant production of the same
US20050059149A1 (en) * 1993-11-22 2005-03-17 Bauer S. Christopher Methods of ex-vivo expansion of hematopoeitic cells using multivariant IL-3 hematopoiesis chimera proteins
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Also Published As

Publication number Publication date
US5817486A (en) 1998-10-06
AU5670994A (en) 1994-06-22
AU690088B2 (en) 1998-04-23
US5604116A (en) 1997-02-18
US20030103936A1 (en) 2003-06-05
JPH08503706A (ja) 1996-04-23
US6479261B1 (en) 2002-11-12
DE69332908D1 (de) 2003-05-28
EP0670898B1 (en) 2003-10-08
ATE251669T1 (de) 2003-10-15
EP1361273A3 (en) 2004-02-11
EP1361273A2 (en) 2003-11-12
CA2150116A1 (en) 1994-06-09
WO1994012639A3 (en) 1994-07-21
DE69333243T2 (de) 2004-08-19
WO1994012638A2 (en) 1994-06-09
EP0672145A1 (en) 1995-09-20
US20040018618A1 (en) 2004-01-29
DK0672145T3 (da) 2003-08-11
US6458931B1 (en) 2002-10-01
AU5612594A (en) 1994-06-22
JPH08503489A (ja) 1996-04-16
US6051217A (en) 2000-04-18
EP1283264A3 (en) 2004-03-10
CA2150117A1 (en) 1994-06-09
US20050244372A1 (en) 2005-11-03
KR100332139B1 (ko) 2002-11-30
WO1994012638A3 (en) 1994-09-01
ES2211875T3 (es) 2004-07-16
AU6078398A (en) 1998-06-18
US5677149A (en) 1997-10-14
ES2198416T3 (es) 2004-02-01
US20030220472A1 (en) 2003-11-27
WO1994012639A2 (en) 1994-06-09
DE69333243D1 (de) 2003-11-13
EP0670898A1 (en) 1995-09-13
EP0672145B1 (en) 2003-04-23
KR950704490A (ko) 1995-11-20
US6440407B1 (en) 2002-08-27
DK0670898T3 (da) 2004-02-09
DE69332908T2 (de) 2003-12-24
EP1283264A2 (en) 2003-02-12
JP2003259886A (ja) 2003-09-16
ATE238421T1 (de) 2003-05-15
PT672145E (pt) 2003-08-29

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