PT2807178T - Polimorfos anidros de nitrato de (2r,3s,4r,5r)-5-(6-(ciclopentilamino)-9h-purin-9-il)-3,4-dihidroxitetrahidrofuran-2-il)}metilo e seus processos de preparação - Google Patents

Polimorfos anidros de nitrato de (2r,3s,4r,5r)-5-(6-(ciclopentilamino)-9h-purin-9-il)-3,4-dihidroxitetrahidrofuran-2-il)}metilo e seus processos de preparação

Info

Publication number
PT2807178T
PT2807178T PT137415022T PT13741502T PT2807178T PT 2807178 T PT2807178 T PT 2807178T PT 137415022 T PT137415022 T PT 137415022T PT 13741502 T PT13741502 T PT 13741502T PT 2807178 T PT2807178 T PT 2807178T
Authority
PT
Portugal
Prior art keywords
dihydroxytetrahydrofuran
cyclopentylamino
purin
processes
preparation
Prior art date
Application number
PT137415022T
Other languages
English (en)
Inventor
K Mcvicar William
Original Assignee
Inotek Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inotek Pharmaceuticals Corp filed Critical Inotek Pharmaceuticals Corp
Publication of PT2807178T publication Critical patent/PT2807178T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
PT137415022T 2012-01-26 2013-01-25 Polimorfos anidros de nitrato de (2r,3s,4r,5r)-5-(6-(ciclopentilamino)-9h-purin-9-il)-3,4-dihidroxitetrahidrofuran-2-il)}metilo e seus processos de preparação PT2807178T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261591037P 2012-01-26 2012-01-26

Publications (1)

Publication Number Publication Date
PT2807178T true PT2807178T (pt) 2017-08-08

Family

ID=48870739

Family Applications (1)

Application Number Title Priority Date Filing Date
PT137415022T PT2807178T (pt) 2012-01-26 2013-01-25 Polimorfos anidros de nitrato de (2r,3s,4r,5r)-5-(6-(ciclopentilamino)-9h-purin-9-il)-3,4-dihidroxitetrahidrofuran-2-il)}metilo e seus processos de preparação

Country Status (25)

Country Link
US (2) US9278991B2 (pt)
EP (2) EP3235825A1 (pt)
JP (2) JP2015508751A (pt)
KR (1) KR20140128974A (pt)
CN (1) CN104093731B (pt)
AU (2) AU2013211957B2 (pt)
BR (1) BR112014018413A8 (pt)
CA (1) CA2861009A1 (pt)
CY (1) CY1119271T1 (pt)
DK (1) DK2807178T3 (pt)
EA (1) EA027109B1 (pt)
ES (1) ES2637332T3 (pt)
HR (1) HRP20171204T1 (pt)
HU (1) HUE035750T2 (pt)
IL (1) IL233812A0 (pt)
IN (1) IN2014DN05987A (pt)
LT (1) LT2807178T (pt)
MX (1) MX2014009086A (pt)
NZ (1) NZ627778A (pt)
PL (1) PL2807178T3 (pt)
PT (1) PT2807178T (pt)
RS (1) RS56150B1 (pt)
SG (2) SG10201701343QA (pt)
SI (1) SI2807178T1 (pt)
WO (1) WO2013112850A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2012010724A (es) 2010-03-26 2012-11-12 Inotek Pharmaceuticals Corp Metodo para reducir la presion intraocular en seres humanos empleando n6-ciclopentiladenosina (cpa), derivados de cpa o profarmacos de los mismos.
BR112014018413A8 (pt) 2012-01-26 2017-07-11 Inotek Pharmaceuticals Corp Polimorfos anidros de nitrato de metila [(2r,3s,4r,5r)-5-(6-(ciclopentilamino)-9h-purin-9-il)-3,4-diidroxitetraidrofuran-2-il)] e processos de preparação do mesmo
SG11201506882YA (en) 2013-03-15 2015-09-29 Inotek Pharmaceuticals Corp Ophthalmic formulations

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Also Published As

Publication number Publication date
CN104093731B (zh) 2017-05-24
LT2807178T (lt) 2017-08-25
AU2017204674A1 (en) 2017-07-27
ES2637332T3 (es) 2017-10-11
EP2807178A4 (en) 2015-09-16
EA027109B1 (ru) 2017-06-30
US9718853B2 (en) 2017-08-01
AU2013211957A1 (en) 2014-08-14
SG10201701343QA (en) 2017-04-27
JP2015508751A (ja) 2015-03-23
JP2018024636A (ja) 2018-02-15
US9278991B2 (en) 2016-03-08
RS56150B1 (sr) 2017-11-30
MX2014009086A (es) 2015-06-05
HRP20171204T1 (hr) 2017-10-06
HUE035750T2 (en) 2018-05-28
CA2861009A1 (en) 2013-08-01
EP2807178B9 (en) 2017-11-29
IL233812A0 (en) 2014-09-30
CN104093731A (zh) 2014-10-08
EP3235825A1 (en) 2017-10-25
SI2807178T1 (sl) 2017-09-29
WO2013112850A1 (en) 2013-08-01
SG11201403979TA (en) 2014-08-28
US20130196940A1 (en) 2013-08-01
AU2013211957B2 (en) 2017-08-10
NZ627778A (en) 2017-01-27
CY1119271T1 (el) 2018-02-14
US20160137686A1 (en) 2016-05-19
PL2807178T3 (pl) 2017-12-29
BR112014018413A8 (pt) 2017-07-11
BR112014018413A2 (pt) 2017-06-20
KR20140128974A (ko) 2014-11-06
EP2807178A1 (en) 2014-12-03
IN2014DN05987A (pt) 2015-06-26
EA201491393A1 (ru) 2015-01-30
DK2807178T3 (en) 2017-09-04
EP2807178B1 (en) 2017-05-17

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