PT1319007E - Compostos de succinimida heterociclicos fundidos e seus analogos enquanto moduladores da funcao dos receptores hormonais nucleares - Google Patents

Compostos de succinimida heterociclicos fundidos e seus analogos enquanto moduladores da funcao dos receptores hormonais nucleares

Info

Publication number
PT1319007E
PT1319007E PT01948503T PT01948503T PT1319007E PT 1319007 E PT1319007 E PT 1319007E PT 01948503 T PT01948503 T PT 01948503T PT 01948503 T PT01948503 T PT 01948503T PT 1319007 E PT1319007 E PT 1319007E
Authority
PT
Portugal
Prior art keywords
analogs
fused heterocyclic
succinimide compounds
compounds
function modulators
Prior art date
Application number
PT01948503T
Other languages
English (en)
Inventor
Mark E Salvati
Balog James Aaron
Dacia A Pickering
Giese Soeren
Fura Aberra
Li Wenying
Ramesh N Patel
Ronald L Hanson
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of PT1319007E publication Critical patent/PT1319007E/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P5/00—Drugs for disorders of the endocrine system
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
PT01948503T 2000-09-19 2001-06-20 Compostos de succinimida heterociclicos fundidos e seus analogos enquanto moduladores da funcao dos receptores hormonais nucleares PT1319007E (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23351900P 2000-09-19 2000-09-19
US28473001P 2001-04-18 2001-04-18
US28443801P 2001-04-18 2001-04-18

Publications (1)

Publication Number Publication Date
PT1319007E true PT1319007E (pt) 2006-05-31

Family

ID=27398441

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01948503T PT1319007E (pt) 2000-09-19 2001-06-20 Compostos de succinimida heterociclicos fundidos e seus analogos enquanto moduladores da funcao dos receptores hormonais nucleares

Country Status (36)

Country Link
US (1) US20040176324A1 (pt)
EP (1) EP1319007B9 (pt)
JP (1) JP4966477B2 (pt)
KR (1) KR100765670B1 (pt)
CN (2) CN1307181C (pt)
AR (1) AR035340A1 (pt)
AT (1) ATE318822T1 (pt)
AU (2) AU6994301A (pt)
BG (1) BG107675A (pt)
BR (1) BR0113980A (pt)
CA (1) CA2423071A1 (pt)
CZ (1) CZ2003780A3 (pt)
DE (1) DE60117551T2 (pt)
DK (1) DK1319007T3 (pt)
EE (1) EE200300108A (pt)
ES (1) ES2260244T3 (pt)
GE (1) GEP20074144B (pt)
HK (1) HK1054230B (pt)
HR (1) HRP20030305B9 (pt)
HU (1) HUP0400455A3 (pt)
IL (1) IL155019A0 (pt)
IS (1) IS6750A (pt)
MX (1) MXPA03002412A (pt)
MY (1) MY138531A (pt)
NO (1) NO329931B1 (pt)
NZ (1) NZ524803A (pt)
PE (1) PE20020729A1 (pt)
PL (1) PL361707A1 (pt)
PT (1) PT1319007E (pt)
SK (1) SK4982003A3 (pt)
TW (1) TWI305208B (pt)
UA (1) UA78686C2 (pt)
UY (1) UY26808A1 (pt)
WO (1) WO2002024702A1 (pt)
YU (1) YU20003A (pt)
ZA (1) ZA200302963B (pt)

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AR035340A1 (es) 2004-05-12
HRP20030305B1 (en) 2007-12-31
CN1995039A (zh) 2007-07-11
US20040176324A1 (en) 2004-09-09
NZ524803A (en) 2004-09-24
BG107675A (bg) 2003-12-31
KR20030028847A (ko) 2003-04-10
WO2002024702A1 (en) 2002-03-28
CN1608069A (zh) 2005-04-20
EP1319007A1 (en) 2003-06-18
ZA200302963B (en) 2004-07-15
EP1319007B9 (en) 2007-10-10
HK1054230A1 (en) 2003-11-21
HRP20030305A2 (en) 2005-04-30
UY26808A1 (es) 2002-01-31
YU20003A (sh) 2006-03-03
MY138531A (en) 2009-06-30
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