PL375693A1 - Estry kwasu aldonowego, sposób ich wytwarzania i sposób wytwarzania substancji farmaceutycznie czynnych sprzężonych za pomocą wolnych grup aminowych z polisacharydami lub pochodnymi polisacharydów - Google Patents

Estry kwasu aldonowego, sposób ich wytwarzania i sposób wytwarzania substancji farmaceutycznie czynnych sprzężonych za pomocą wolnych grup aminowych z polisacharydami lub pochodnymi polisacharydów

Info

Publication number
PL375693A1
PL375693A1 PL03375693A PL37569303A PL375693A1 PL 375693 A1 PL375693 A1 PL 375693A1 PL 03375693 A PL03375693 A PL 03375693A PL 37569303 A PL37569303 A PL 37569303A PL 375693 A1 PL375693 A1 PL 375693A1
Authority
PL
Poland
Prior art keywords
methods
producing
polysaccharides
acid esters
active ingredients
Prior art date
Application number
PL03375693A
Other languages
English (en)
Other versions
PL210453B1 (pl
Inventor
Klaus Sommermeyer
Original Assignee
Supramol Parenteral Colloids Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Supramol Parenteral Colloids Gmbh filed Critical Supramol Parenteral Colloids Gmbh
Publication of PL375693A1 publication Critical patent/PL375693A1/pl
Publication of PL210453B1 publication Critical patent/PL210453B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/02—Esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/16—Ether-esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/18—Oxidised starch
    • C08B31/185—Derivatives of oxidised starch, e.g. crosslinked oxidised starch
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B33/00—Preparation of derivatives of amylose
    • C08B33/02—Esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B35/00—Preparation of derivatives of amylopectin
    • C08B35/02—Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL375693A 2002-12-04 2003-12-03 Ester kwasu aldonowego, substancja stała zawierająca ten ester, roztwór zawierający ten ester, sposób jego wytwarzania, sposób wytwarzania substancji farmaceutycznie czynnych sprzężonych za pomocą wolnych grup aminowych z polisacharydami lub pochodnymi polisacharydów oraz farmaceutyczna substancja czynna PL210453B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10256558A DE10256558A1 (de) 2002-12-04 2002-12-04 Ester von Polysaccharid Aldonsäuren, Verfahren zu ihrer Herstellung und Verwendung zur Kopplung an pharmazeutische Wirkstoffe

Publications (2)

Publication Number Publication Date
PL375693A1 true PL375693A1 (pl) 2005-12-12
PL210453B1 PL210453B1 (pl) 2012-01-31

Family

ID=32403695

Family Applications (1)

Application Number Title Priority Date Filing Date
PL375693A PL210453B1 (pl) 2002-12-04 2003-12-03 Ester kwasu aldonowego, substancja stała zawierająca ten ester, roztwór zawierający ten ester, sposób jego wytwarzania, sposób wytwarzania substancji farmaceutycznie czynnych sprzężonych za pomocą wolnych grup aminowych z polisacharydami lub pochodnymi polisacharydów oraz farmaceutyczna substancja czynna

Country Status (15)

Country Link
US (1) US20060052342A1 (pl)
EP (1) EP1567558A2 (pl)
JP (1) JP4749720B2 (pl)
KR (1) KR101170033B1 (pl)
CN (1) CN100535015C (pl)
AU (1) AU2003288218B2 (pl)
BR (1) BR0316493A (pl)
CA (1) CA2504799A1 (pl)
DE (1) DE10256558A1 (pl)
MX (1) MXPA05005572A (pl)
NO (1) NO20053179L (pl)
PL (1) PL210453B1 (pl)
RU (1) RU2330046C2 (pl)
WO (1) WO2004050710A2 (pl)
ZA (1) ZA200503135B (pl)

Families Citing this family (16)

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DE10112825A1 (de) 2001-03-16 2002-10-02 Fresenius Kabi De Gmbh HESylierung von Wirkstoffen in wässriger Lösung
DE10209822A1 (de) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
DE10209821A1 (de) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung von Proteinen an ein modifiziertes Polysaccharid
KR101045422B1 (ko) 2002-09-11 2011-06-30 프레제니우스 카비 도이치란트 게엠베하 하이드록시알킬 전분 유도체의 제조 방법
US7538092B2 (en) 2002-10-08 2009-05-26 Fresenius Kabi Deutschland Gmbh Pharmaceutically active oligosaccharide conjugates
WO2005014655A2 (en) 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
CN1917905B (zh) * 2004-02-09 2012-01-04 诺松制药股份公司 从多糖和多核苷酸生产缀合物的方法
DE102004009783A1 (de) * 2004-02-28 2005-09-15 Supramol Parenteral Colloids Gmbh Hyperverzweigte Stärkefraktion, Verfahren zu ihrer Herstellung und ihre Konjugate mit pharmazeutischen Wirkstoffen
DE202005021885U1 (de) 2004-03-11 2011-03-03 Fresenius Kabi Deutschland Gmbh Hydroxyalkylstärke-Protein-Konjugate, durch reduktive Aminierung hergestellt
EP2070951A1 (en) * 2007-12-14 2009-06-17 Fresenius Kabi Deutschland GmbH Method for producing a hydroxyalkyl starch derivatives with two linkers
EP2070950A1 (en) 2007-12-14 2009-06-17 Fresenius Kabi Deutschland GmbH Hydroxyalkyl starch derivatives and process for their preparation
AU2009242038B2 (en) 2008-05-02 2013-05-30 Novartis Ag Improved fibronectin-based binding molecules and uses thereof
WO2011051327A2 (en) 2009-10-30 2011-05-05 Novartis Ag Small antibody-like single chain proteins
WO2011051466A1 (en) 2009-11-02 2011-05-05 Novartis Ag Anti-idiotypic fibronectin-based binding molecules and uses thereof
WO2011092233A1 (en) 2010-01-29 2011-08-04 Novartis Ag Yeast mating to produce high-affinity combinations of fibronectin-based binders
WO2013113503A1 (en) 2012-01-31 2013-08-08 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and an oligonucleotide

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US2868781A (en) * 1956-04-23 1959-01-13 Monsanto Chemicals Carbohydrate esters of carboxylic acids and methods of preparing same
US4125492A (en) * 1974-05-31 1978-11-14 Pedro Cuatrecasas Affinity chromatography of vibrio cholerae enterotoxin-ganglioside polysaccharide and the biological effects of ganglioside-containing soluble polymers
EP0019403B1 (en) * 1979-05-10 1985-07-31 American Hospital Supply Corporation Hydroxyalkyl-starch drug carrier
DE3029307A1 (de) * 1980-08-01 1982-03-04 Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG, 6380 Bad Homburg Haemoglobin enthaltendes blutersatzmittel
DE3836600A1 (de) * 1988-10-27 1990-05-03 Wolff Walsrode Ag Kohlensaeureester von polysacchariden und verfahren zu ihrer herstellung
JP2896580B2 (ja) * 1989-08-25 1999-05-31 チッソ株式会社 アミロース―リゾチームハイブリッドと活性化糖およびその製造法
DE4130807A1 (de) * 1991-09-17 1993-03-18 Wolff Walsrode Ag Verfahren zur herstellung von polysaccharidcarbonaten
NZ250048A (en) * 1992-10-28 1994-10-26 Enzyme Bio Systems Ltd Production of maltodextrins by selective hydrolysation of starches by enzymatic methods
DE19628705A1 (de) * 1996-07-08 1998-01-15 Fresenius Ag Neue Sauerstoff-Transport-Mittel, diese enthaltende Hämoglobin-Hydroxyethylstärke-Konjugate, Verfahren zu deren Herstellung, sowie deren Verwendung als Blutersatzstoffe
US5753468A (en) * 1996-08-05 1998-05-19 National Starch And Chemical Investment Holding Corporation Stable high viscosity starch based adhesive and method of preparation
US6011008A (en) * 1997-01-08 2000-01-04 Yissum Research Developement Company Of The Hebrew University Of Jerusalem Conjugates of biologically active substances
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RO122279B1 (ro) * 2001-08-22 2009-03-30 Supramol Parenteral Colloids Gmbh Amilopectină hiperramificată pentru utilizare în tratamentul chirurgical şi terapeutic la mamifere sau pentru metode de diagnostic, în special, pentru utilizare ca expandor de volum al plasmei
US7179617B2 (en) * 2001-10-10 2007-02-20 Neose Technologies, Inc. Factor IX: remolding and glycoconjugation of Factor IX
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US7274854B2 (en) * 2002-06-27 2007-09-25 Pirelli & C. S.P.A. Polyimide optical waveguides and method for the preparation thereof
KR101045422B1 (ko) * 2002-09-11 2011-06-30 프레제니우스 카비 도이치란트 게엠베하 하이드록시알킬 전분 유도체의 제조 방법
DE10302520A1 (de) * 2003-01-23 2004-08-05 Supramol Parenteral Colloids Gmbh Kohlensäurediester von Stärkefraktionen und deren Derivate, Verfahren zu ihrer Herstellung und Verwendung zur Kopplung an pharmazeutische Wirkstoffe
WO2005014655A2 (en) * 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
BRPI0413450A (pt) * 2003-08-08 2006-10-17 Fresenius Kabi De Gmbh conjugados de hidroxialquil amido e g-csf
DE102004009783A1 (de) * 2004-02-28 2005-09-15 Supramol Parenteral Colloids Gmbh Hyperverzweigte Stärkefraktion, Verfahren zu ihrer Herstellung und ihre Konjugate mit pharmazeutischen Wirkstoffen
AR048918A1 (es) * 2004-03-11 2006-06-14 Fresenius Kabi De Gmbh Conjugados de almidon de hidroxietilo y eritropoyetina

Also Published As

Publication number Publication date
US20060052342A1 (en) 2006-03-09
PL210453B1 (pl) 2012-01-31
RU2330046C2 (ru) 2008-07-27
NO20053179L (no) 2005-08-15
BR0316493A (pt) 2005-10-11
JP4749720B2 (ja) 2011-08-17
WO2004050710A3 (de) 2004-09-02
EP1567558A2 (de) 2005-08-31
WO2004050710A2 (de) 2004-06-17
CN100535015C (zh) 2009-09-02
KR101170033B1 (ko) 2012-08-01
KR20050072832A (ko) 2005-07-12
DE10256558A1 (de) 2004-09-16
RU2005120736A (ru) 2006-01-20
AU2003288218A1 (en) 2004-06-23
CN1720264A (zh) 2006-01-11
ZA200503135B (en) 2006-07-26
JP2006509849A (ja) 2006-03-23
MXPA05005572A (es) 2005-11-23
NO20053179D0 (no) 2005-06-28
AU2003288218B2 (en) 2010-05-20
CA2504799A1 (en) 2004-06-17

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