PL366933A1 - Zastosowanie pochodnych fenylu, fenolu i benzoilu, podstawionych trifluoroacetyloalkilem do leczenia i/lub zapobiegania przed otyłością oraz chorobami towarzyszącymi i/lub będącymi jej następstwem - Google Patents
Zastosowanie pochodnych fenylu, fenolu i benzoilu, podstawionych trifluoroacetyloalkilem do leczenia i/lub zapobiegania przed otyłością oraz chorobami towarzyszącymi i/lub będącymi jej następstwemInfo
- Publication number
- PL366933A1 PL366933A1 PL02366933A PL36693302A PL366933A1 PL 366933 A1 PL366933 A1 PL 366933A1 PL 02366933 A PL02366933 A PL 02366933A PL 36693302 A PL36693302 A PL 36693302A PL 366933 A1 PL366933 A1 PL 366933A1
- Authority
- PL
- Poland
- Prior art keywords
- derivatives
- diseases
- substituted phenyl
- obesity
- treatment
- Prior art date
Links
- 125000003236 benzoyl group Chemical class [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 title abstract 3
- 208000008589 Obesity Diseases 0.000 title abstract 2
- 235000020824 obesity Nutrition 0.000 title abstract 2
- 208000037921 secondary disease Diseases 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 150000002989 phenols Chemical class 0.000 title 1
- 125000001997 phenyl group Chemical class [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title 1
- 238000011321 prophylaxis Methods 0.000 title 1
- 125000004044 trifluoroacetyl group Chemical group FC(C(=O)*)(F)F 0.000 title 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 trifluoroacetyl-substituted phenyl Chemical group 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 102000004882 Lipase Human genes 0.000 abstract 1
- 108090001060 Lipase Proteins 0.000 abstract 1
- 239000004367 Lipase Substances 0.000 abstract 1
- 208000001145 Metabolic Syndrome Diseases 0.000 abstract 1
- 102000019280 Pancreatic lipases Human genes 0.000 abstract 1
- 108050006759 Pancreatic lipases Proteins 0.000 abstract 1
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 229940040461 lipase Drugs 0.000 abstract 1
- 235000019421 lipase Nutrition 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229940116369 pancreatic lipase Drugs 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10135027A DE10135027A1 (de) | 2001-07-18 | 2001-07-18 | Verwendung Trifluoracetylalkyl-substituierter Phenyl-, Phenol- und Benzoylderivate in der Behandlung und/oder Prophylaxe von Obestias und deren Begleit- und/oder Folgeerkrankungen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL366933A1 true PL366933A1 (pl) | 2005-02-07 |
| PL216996B1 PL216996B1 (pl) | 2014-06-30 |
Family
ID=7692273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL366933A PL216996B1 (pl) | 2001-07-18 | 2002-07-12 | Zastosowanie pochodnych fenylu, fenolu i benzoilu, podstawionych trifluoroacetyloalkilem do wytwarzania preparatów farmaceutycznych do leczenia i/lub zapobiegania przed otyłością oraz zespołem metabolicznym, związki stanowiące powyższe pochodne, związki te do stosowania jako środki lecznicze oraz sposób ich wytwarzania |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6930207B2 (pl) |
| EP (1) | EP1420771B9 (pl) |
| JP (1) | JP4511172B2 (pl) |
| CN (1) | CN1596106B (pl) |
| AT (1) | ATE338542T1 (pl) |
| AU (1) | AU2002328884B8 (pl) |
| BR (1) | BR0211196A (pl) |
| CA (1) | CA2455483C (pl) |
| DE (2) | DE10135027A1 (pl) |
| MX (1) | MXPA04000325A (pl) |
| PL (1) | PL216996B1 (pl) |
| WO (1) | WO2003007923A2 (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102151262A (zh) * | 2001-06-12 | 2011-08-17 | 维尔斯达医疗公司 | 用于治疗代谢失调的化合物 |
| CN1750758B (zh) * | 2003-02-13 | 2012-06-20 | 维尔斯达医疗公司 | 用于治疗代谢紊乱的化合物 |
| RU2403237C2 (ru) * | 2004-05-14 | 2010-11-10 | Эмисфире Текнолоджис, Инк. | Составы и смеси для доставки активных агентов |
| KR100733516B1 (ko) | 2005-09-29 | 2007-06-29 | 노키아 코포레이션 | 네트워크 기반 서비스들을 중개하는 네트워크 서비스 제공장치, 휴대용 전자 장치, 시스템 및 방법 |
| CA2658887C (en) * | 2006-07-28 | 2016-08-23 | University Of Connecticut | Fatty acid amide hydrolase inhibitors |
| CN101594858A (zh) * | 2007-01-29 | 2009-12-02 | 亚瑞特医疗公司 | 用于治疗代谢综合症和相关病症的可溶性环氧化物水解酶抑制剂 |
| EP2139836A1 (en) * | 2007-04-05 | 2010-01-06 | The Royal Institution for the Advancement of Learning/McGill University | Perfluoroketone compounds and uses thereof |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3046300A (en) * | 1960-10-21 | 1962-07-24 | Merck & Co Inc | alpha-trifluoromethyloxyphenylalanines |
| ZA714221B (en) * | 1970-07-10 | 1972-03-29 | Astra Ab | Insecticides |
| US4051223A (en) * | 1975-11-10 | 1977-09-27 | General Mills Chemicals, Inc. | Process for the recovery of magnesium |
| DE2918775A1 (de) * | 1979-05-10 | 1980-11-20 | Merck Patent Gmbh | Diketone, verfahren zu ihrer herstellung und ihre verwendung als komponenten fluessigkristalliner dielektrika |
| US4408077A (en) * | 1981-11-13 | 1983-10-04 | Ayerst, Mckeena & Harrison, Inc. | 6-(Lower alkoxy)-5-(trifluoromethyl)-1-naphthalenecarboxaldehydes |
| WO1987002367A2 (en) * | 1985-10-18 | 1987-04-23 | The Upjohn Company | Cyclic hydrocarbons with an aminoalkyl sidechain |
| DE3872234T2 (de) * | 1987-04-16 | 1993-01-07 | Upjohn Co | Zyklische kohlenwasserstoffe mit aminoalkyl-seitenkette. |
| FR2614725B1 (fr) * | 1987-04-28 | 1992-10-30 | Rhone Poulenc Chimie | Procede d'elimination de la radioactivite d'effluents par extraction liquide-liquide |
| FR2623798B1 (fr) * | 1987-11-26 | 1990-05-04 | Lucien Laboratoires | Derives de trifluoromethyl-1 tetralines, leur preparation et leur application pour la synthese de composes presentant des proprietes therapeutiques |
| US4962024A (en) * | 1988-08-11 | 1990-10-09 | Becton, Dickinson And Company | Signal enhancement in assay for an enzyme |
| FR2701259B1 (fr) * | 1993-02-08 | 1995-03-24 | Rhone Poulenc Agrochimie | Procédé pour la préparation de dérivés phénylbenzamides fongicides agricoles. |
| CA2277954A1 (en) * | 1993-11-30 | 1995-06-08 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation |
| DE19649093A1 (de) * | 1996-11-27 | 1998-05-28 | Bayer Ag | Mikrobizide Mittel auf Basis von Thiophen-2-carbonsäure-Derivaten |
| WO1999015129A2 (en) * | 1997-09-23 | 1999-04-01 | Bristol-Myers Squibb Company | SELECTIVE cPLA2 INHIBITORS |
| GB9900416D0 (en) * | 1999-01-08 | 1999-02-24 | Alizyme Therapeutics Ltd | Inhibitors |
| GB9910378D0 (en) * | 1999-05-05 | 1999-06-30 | Smithkline Beecham Plc | Novel compounds |
| DE60001623T2 (de) * | 1999-12-03 | 2003-12-18 | Pfizer Products Inc., Groton | Sulfamoylheteroarylpyrazolverbindungen zur Verwendung als analgetisches/entzündungshemmendes Mittel |
| MXPA02005539A (es) * | 1999-12-03 | 2002-09-02 | Pfizer Prod Inc | Derivados de heterociclo-alquilsulfonil-pirazol como agentes anti-inflamatorios/analgesicos. |
| TR200001872A2 (tr) * | 2000-06-26 | 2002-01-21 | Fako �La�Lari A.� | 4-[5-(4-Metilfenil-3-(triflorometil)-1H-pirazol-1-il] benzensulfonamit' in yeni kristal biçimi "Biçim I" ve bu ürünün üretilmesine ilişkin yöntem. |
| US20020103192A1 (en) * | 2000-10-26 | 2002-08-01 | Curtin Michael L. | Inhibitors of histone deacetylase |
-
2001
- 2001-07-18 DE DE10135027A patent/DE10135027A1/de not_active Withdrawn
-
2002
- 2002-07-12 DE DE50208081T patent/DE50208081D1/de not_active Expired - Lifetime
- 2002-07-12 CN CN028142950A patent/CN1596106B/zh not_active Expired - Fee Related
- 2002-07-12 CA CA2455483A patent/CA2455483C/en not_active Expired - Fee Related
- 2002-07-12 WO PCT/EP2002/007782 patent/WO2003007923A2/de not_active Ceased
- 2002-07-12 BR BR0211196-9A patent/BR0211196A/pt active Search and Examination
- 2002-07-12 JP JP2003513532A patent/JP4511172B2/ja not_active Expired - Fee Related
- 2002-07-12 MX MXPA04000325A patent/MXPA04000325A/es active IP Right Grant
- 2002-07-12 AU AU2002328884A patent/AU2002328884B8/en not_active Ceased
- 2002-07-12 AT AT02764680T patent/ATE338542T1/de not_active IP Right Cessation
- 2002-07-12 PL PL366933A patent/PL216996B1/pl unknown
- 2002-07-12 EP EP02764680A patent/EP1420771B9/de not_active Expired - Lifetime
-
2004
- 2004-01-16 US US10/758,240 patent/US6930207B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE338542T1 (de) | 2006-09-15 |
| WO2003007923A2 (de) | 2003-01-30 |
| US20040214901A1 (en) | 2004-10-28 |
| BR0211196A (pt) | 2004-10-26 |
| EP1420771B9 (de) | 2007-10-17 |
| WO2003007923A3 (de) | 2004-01-08 |
| CN1596106B (zh) | 2011-05-11 |
| CA2455483A1 (en) | 2003-01-30 |
| PL216996B1 (pl) | 2014-06-30 |
| CA2455483C (en) | 2012-01-24 |
| EP1420771B1 (de) | 2006-09-06 |
| HK1073245A1 (en) | 2005-09-30 |
| DE50208081D1 (de) | 2006-10-19 |
| JP4511172B2 (ja) | 2010-07-28 |
| AU2002328884B2 (en) | 2008-02-07 |
| DE10135027A1 (de) | 2003-02-06 |
| US6930207B2 (en) | 2005-08-16 |
| JP2005500329A (ja) | 2005-01-06 |
| AU2002328884B8 (en) | 2008-06-26 |
| MXPA04000325A (es) | 2005-03-07 |
| CN1596106A (zh) | 2005-03-16 |
| EP1420771A2 (de) | 2004-05-26 |
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| PL366933A1 (pl) | Zastosowanie pochodnych fenylu, fenolu i benzoilu, podstawionych trifluoroacetyloalkilem do leczenia i/lub zapobiegania przed otyłością oraz chorobami towarzyszącymi i/lub będącymi jej następstwem | |
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