PL354180A1 - Izomeryczne skondensowane pirolokarbazole i izoindIzomeryczne skondensowane pirolokarbazole i izoindolonyolony - Google Patents
Izomeryczne skondensowane pirolokarbazole i izoindIzomeryczne skondensowane pirolokarbazole i izoindolonyolonyInfo
- Publication number
- PL354180A1 PL354180A1 PL00354180A PL35418000A PL354180A1 PL 354180 A1 PL354180 A1 PL 354180A1 PL 00354180 A PL00354180 A PL 00354180A PL 35418000 A PL35418000 A PL 35418000A PL 354180 A1 PL354180 A1 PL 354180A1
- Authority
- PL
- Poland
- Prior art keywords
- isoindolones
- fused pyrrolocarbazoles
- isomeric fused
- directed
- same
- Prior art date
Links
- XTBAPWCYTNCZTO-UHFFFAOYSA-N isoindol-1-one Chemical class C1=CC=C2C(=O)N=CC2=C1 XTBAPWCYTNCZTO-UHFFFAOYSA-N 0.000 title abstract 2
- QNMMYUBZGLXCCK-UHFFFAOYSA-N pyrrolo[3,2-a]carbazole Chemical class N1=C2C=CC=CC2=C2C1=C1C=CN=C1C=C2 QNMMYUBZGLXCCK-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000009007 Diagnostic Kit Methods 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15036799P | 1999-08-20 | 1999-08-20 | |
US09/640,825 US6399780B1 (en) | 1999-08-20 | 2000-08-17 | Isomeric fused pyrrolocarbazoles and isoindolones |
Publications (1)
Publication Number | Publication Date |
---|---|
PL354180A1 true PL354180A1 (pl) | 2003-12-29 |
Family
ID=26847579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL00354180A PL354180A1 (pl) | 1999-08-20 | 2000-08-18 | Izomeryczne skondensowane pirolokarbazole i izoindIzomeryczne skondensowane pirolokarbazole i izoindolonyolony |
Country Status (26)
Country | Link |
---|---|
US (4) | US6399780B1 (pl) |
EP (1) | EP1206473B1 (pl) |
JP (1) | JP4776842B2 (pl) |
KR (1) | KR100756686B1 (pl) |
CN (1) | CN1370173A (pl) |
AT (1) | ATE280172T1 (pl) |
AU (1) | AU776475C (pl) |
BG (1) | BG65545B1 (pl) |
BR (1) | BR0013811A (pl) |
CA (1) | CA2381885C (pl) |
CZ (1) | CZ2002616A3 (pl) |
DE (1) | DE60015153T2 (pl) |
EA (1) | EA005920B1 (pl) |
ES (1) | ES2230140T3 (pl) |
HK (1) | HK1046904B (pl) |
HU (1) | HUP0202758A3 (pl) |
IL (2) | IL148180A0 (pl) |
IS (1) | IS2186B (pl) |
MX (1) | MXPA02001789A (pl) |
NO (1) | NO323375B1 (pl) |
NZ (1) | NZ517174A (pl) |
PL (1) | PL354180A1 (pl) |
PT (1) | PT1206473E (pl) |
SK (1) | SK286805B6 (pl) |
TR (1) | TR200200474T2 (pl) |
WO (1) | WO2001014380A1 (pl) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6399780B1 (en) * | 1999-08-20 | 2002-06-04 | Cephalon, Inc. | Isomeric fused pyrrolocarbazoles and isoindolones |
US7122679B2 (en) * | 2000-05-09 | 2006-10-17 | Cephalon, Inc. | Multicyclic compounds and the use thereof |
AR035971A1 (es) * | 2001-05-16 | 2004-07-28 | Cephalon Inc | Metodos para el tratamiento y la prevencion del dolor |
ATE404550T1 (de) * | 2001-09-21 | 2008-08-15 | Smithkline Beecham Corp | Chemische verbindungen |
SE0104140D0 (sv) * | 2001-12-07 | 2001-12-07 | Astrazeneca Ab | Novel Compounds |
UA80447C2 (en) * | 2002-10-08 | 2007-09-25 | Methods for treating pain by administering nerve growth factor antagonist and opioid analgesic | |
AU2003304238A1 (en) * | 2002-10-08 | 2005-01-13 | Rinat Neuroscience Corp. | Methods for treating post-surgical pain by administering an anti-nerve growth factor antagonist antibody and compositions containing the same |
AU2003285864C1 (en) | 2002-10-08 | 2010-07-01 | Rinat Neuroscience Corp. | Methods for treating post-surgical pain by administering a nerve growth factor antagonist and compositions containing the same |
US7569364B2 (en) * | 2002-12-24 | 2009-08-04 | Pfizer Inc. | Anti-NGF antibodies and methods using same |
EP2270048B1 (en) | 2002-12-24 | 2015-11-11 | Rinat Neuroscience Corp. | Anti-NGF antibodies and methods using same |
US9498530B2 (en) | 2002-12-24 | 2016-11-22 | Rinat Neuroscience Corp. | Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same |
PL379983A1 (pl) | 2003-02-19 | 2006-11-27 | Rinat Neuroscience Corp. | Sposoby leczenia bólu polegające na podaniu antagonisty czynnika wzrostu nerwów i niesteroidowego leku przeciwzapalnego oraz zawierające je kompozycje |
US7169802B2 (en) | 2003-12-23 | 2007-01-30 | Cephalon, Inc. | Fused pyrrolocarbazoles |
KR101637908B1 (ko) * | 2004-04-07 | 2016-07-11 | 리나트 뉴로사이언스 코프. | 신경성장인자 길항제의 투여에 의한 골암 통증의 치료방법 |
US20060058250A1 (en) * | 2004-09-10 | 2006-03-16 | Cephalon, Inc. | Methods of treating proliferative skin diseases using carbazole derivatives |
WO2006034121A1 (en) * | 2004-09-17 | 2006-03-30 | Henry Ford Health System | Methods and compositions for use of angiogenesis inhibitors in the prevention and/or control of epilepsy |
ME02645B (me) | 2005-02-04 | 2012-04-30 | Astrazeneca Ab | Derivati pirazolil-aminopiridina korisni kao inhibitori kinaze |
BRPI0608160A2 (pt) * | 2005-02-16 | 2010-11-09 | Astrazeneca Ab | anticorpo isolado, célula hospedeira, método de inibir o crescimento de células psma+, e, uso de um anticorpo anti-psma defucosilado |
ES2308731T3 (es) * | 2005-02-16 | 2008-12-01 | Astrazeneca Ab | Compuestos quimicos. |
WO2006123113A2 (en) * | 2005-05-16 | 2006-11-23 | Astrazeneca Ab | Pyrazolylaminopyrimidine derivatives useful as tyrosine kinase inhibitors |
EP2388259A1 (en) * | 2005-10-28 | 2011-11-23 | AstraZeneca AB | 4- (3-aminopyrazole) pyrimidine derivatives for use as tyrosine kinase inhibitors in the treatment of cancer |
MX2008013400A (es) | 2006-04-19 | 2008-11-10 | Astellas Pharma Inc | Derivado de azolcarboxamida. |
US20080021013A1 (en) * | 2006-07-21 | 2008-01-24 | Cephalon, Inc. | JAK inhibitors for treatment of myeloproliferative disorders |
US20090326229A1 (en) * | 2006-08-02 | 2009-12-31 | Takeda Phamaceutical Company Limited | Alpha-carboline derivatives and methods for preparation thereof |
EP2081892A4 (en) * | 2006-11-17 | 2014-03-05 | Donald F Weaver | COMPOUNDS AND METHOD FOR THE TREATMENT OF PROTEIN DISAPPEARANCE |
US8889271B2 (en) | 2006-11-26 | 2014-11-18 | Duksan High Metal Co., Ltd. | Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same |
US20100204246A1 (en) * | 2007-04-18 | 2010-08-12 | Astrazeneca Ab | 5-aminopyrazol-3-yl-3h-imidazo (4,5-b) pyridine derivatives and their use for the treatment of cancer |
US20100204231A1 (en) * | 2007-05-04 | 2010-08-12 | Astrazeneca Ab | Amino-thiazolyl-pyrimidine derivatives and their use for the treatment of cancer |
UA99459C2 (en) * | 2007-05-04 | 2012-08-27 | Астразенека Аб | 9-(pyrazol-3-yl)- 9h-purine-2-amine and 3-(pyraz0l-3-yl)-3h-imidazo[4,5-b]pyridin-5-amine derivatives and their use for the treatment of cancer |
JP5321467B2 (ja) | 2007-10-24 | 2013-10-23 | アステラス製薬株式会社 | アゾールカルボキサミド化合物又はその塩 |
WO2009088054A1 (ja) | 2008-01-11 | 2009-07-16 | Astellas Pharma Inc. | 精巣の疼痛又は不快感行動及び頻尿併発モデル動物 |
TW201006830A (en) * | 2008-06-11 | 2010-02-16 | Astrazeneca Ab | Chemical compounds |
MX2011003447A (es) * | 2008-09-30 | 2011-07-29 | Astrazeneca Ab | Inhibidores heterociclicos de jak quinasa. |
AR074374A1 (es) | 2008-11-19 | 2011-01-12 | Cephalon Inc | Formas de un compuesto de pirrolocarbazol fusionado, composiciones que las comprenden y su uso en el tratamiento de la angiogénesis y los tumores sólidos. |
JP5390693B2 (ja) * | 2009-03-30 | 2014-01-15 | ドゥクサン ハイ メタル カンパニー リミテッド | 有機電子素子及びその化合物、端末 |
PL3333188T3 (pl) | 2010-08-19 | 2022-05-09 | Zoetis Belgium S.A. | Przeciwciała anty-ngf i ich zastosowanie |
KR101497122B1 (ko) * | 2011-08-09 | 2015-03-06 | 덕산네오룩스 주식회사 | 2개 이상의 오원자 헤테로고리를 포함하는 화합물 및 이를 이용한 유기전기소자, 그 단말 |
TWI585088B (zh) | 2012-06-04 | 2017-06-01 | 第一三共股份有限公司 | 作爲激酶抑制劑之咪唑并[1,2-b]嗒衍生物 |
AU2013271564A1 (en) | 2012-06-06 | 2014-12-04 | Zoetis Services Llc | Caninized anti-NGF antibodies and methods thereof |
KR101478884B1 (ko) | 2012-12-24 | 2015-01-05 | 충남대학교산학협력단 | 비스인돌일말레이미드계 화합물 및 이의 제조방법 |
RU2020115534A (ru) | 2017-11-23 | 2021-11-08 | Биомед Икс Гмбх | ИНГИБИТОРЫ ТРОПОМИОЗИН-РЕЦЕПТОРНОЙ КИНАЗЫ A (TrkA) И ИХ ПРИМЕНЕНИЕ ДЛЯ ЛЕЧЕНИЯ БОЛИ И РАКА |
CA3093772C (en) | 2018-03-12 | 2024-04-16 | Zoetis Services Llc | Anti-ngf antibodies and methods thereof |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816450A (en) | 1986-09-15 | 1989-03-28 | Duke University | Inhibition of protein kinase C by long-chain bases |
US4735939A (en) | 1987-02-27 | 1988-04-05 | The Dow Chemical Company | Insecticidal activity of staurosporine |
US4923986A (en) | 1987-03-09 | 1990-05-08 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of physiologically active substance K-252 |
JPH07113027B2 (ja) | 1987-12-24 | 1995-12-06 | 協和醗酵工業株式会社 | K−252誘導体 |
FR2631199B1 (fr) | 1988-05-09 | 1991-03-15 | Centre Nat Rech Scient | Reacteur a plasma |
US5621101A (en) | 1992-07-24 | 1997-04-15 | Cephalon, Inc. | Protein kinase inhibitors for treatment of neurological disorders |
CA2163904C (en) | 1993-05-28 | 2000-01-25 | Craig A. Dionne | Use of indolocarbazole derivatives to treat a pathological condition of the prostate |
US5624949A (en) | 1993-12-07 | 1997-04-29 | Eli Lilly And Company | Protein kinase C inhibitors |
US5545636A (en) | 1993-12-23 | 1996-08-13 | Eli Lilly And Company | Protein kinase C inhibitors |
ATE456367T1 (de) | 1993-12-23 | 2010-02-15 | Lilly Co Eli | Proteinkinase c inhibitoren |
GB9416467D0 (en) * | 1994-08-13 | 1994-10-05 | Wellcome Found | Compounds for use in medicine |
US5705511A (en) * | 1994-10-14 | 1998-01-06 | Cephalon, Inc. | Fused pyrrolocarbazoles |
US5475110A (en) * | 1994-10-14 | 1995-12-12 | Cephalon, Inc. | Fused Pyrrolocarbazoles |
US5591855A (en) * | 1994-10-14 | 1997-01-07 | Cephalon, Inc. | Fused pyrrolocarbazoles |
US5594009A (en) * | 1994-10-14 | 1997-01-14 | Cephalon, Inc. | Fused pyrrolocarbazoles |
IL124417A (en) | 1995-11-20 | 2002-11-10 | Lilly Co Eli | Dietary salt of -13 [(dimethyl amino) methyl] - 10, 11, 14, 15 - tetra hydro- 4, 9:16, 21 - our image - H13, H1 - Divenzo {E, K} pyrrole [H-4, 3] [1, 4, 13] Oxadiazacyclohexadecin - 1, 3 (H2) - Discussion, preparation and pharmacological preparations for the inhibition of protein kinase C containing it |
US5808060A (en) * | 1995-12-11 | 1998-09-15 | Cephalon, Inc. | Fused isoindolones |
US5616724A (en) | 1996-02-21 | 1997-04-01 | Cephalon, Inc. | Fused pyrrolo[2,3-c]carbazole-6-ones |
DK0971717T3 (da) | 1996-08-22 | 2002-03-25 | Bristol Myers Squibb Co | Cytotoksiske aminosukker- og relaterede sukkerderivater af indolopyrrolocarbazoler |
US6399780B1 (en) * | 1999-08-20 | 2002-06-04 | Cephalon, Inc. | Isomeric fused pyrrolocarbazoles and isoindolones |
-
2000
- 2000-08-17 US US09/640,825 patent/US6399780B1/en not_active Expired - Lifetime
- 2000-08-18 ES ES00954136T patent/ES2230140T3/es not_active Expired - Lifetime
- 2000-08-18 IL IL14818000A patent/IL148180A0/xx active IP Right Grant
- 2000-08-18 HU HU0202758A patent/HUP0202758A3/hu unknown
- 2000-08-18 WO PCT/US2000/022724 patent/WO2001014380A1/en active IP Right Grant
- 2000-08-18 TR TR2002/00474T patent/TR200200474T2/xx unknown
- 2000-08-18 AU AU66471/00A patent/AU776475C/en not_active Ceased
- 2000-08-18 EA EA200200271A patent/EA005920B1/ru not_active IP Right Cessation
- 2000-08-18 CN CN00811850A patent/CN1370173A/zh active Pending
- 2000-08-18 CZ CZ2002616A patent/CZ2002616A3/cs unknown
- 2000-08-18 EP EP00954136A patent/EP1206473B1/en not_active Expired - Lifetime
- 2000-08-18 KR KR1020027002117A patent/KR100756686B1/ko not_active IP Right Cessation
- 2000-08-18 CA CA002381885A patent/CA2381885C/en not_active Expired - Fee Related
- 2000-08-18 JP JP2001518711A patent/JP4776842B2/ja not_active Expired - Fee Related
- 2000-08-18 BR BR0013811-8A patent/BR0013811A/pt not_active Application Discontinuation
- 2000-08-18 DE DE60015153T patent/DE60015153T2/de not_active Expired - Lifetime
- 2000-08-18 PT PT00954136T patent/PT1206473E/pt unknown
- 2000-08-18 PL PL00354180A patent/PL354180A1/pl unknown
- 2000-08-18 SK SK246-2002A patent/SK286805B6/sk not_active IP Right Cessation
- 2000-08-18 MX MXPA02001789A patent/MXPA02001789A/es active IP Right Grant
- 2000-08-18 AT AT00954136T patent/ATE280172T1/de active
- 2000-08-18 NZ NZ517174A patent/NZ517174A/en unknown
-
2002
- 2002-02-01 US US10/062,159 patent/US6635669B2/en not_active Expired - Lifetime
- 2002-02-12 IS IS6266A patent/IS2186B/is unknown
- 2002-02-14 IL IL148180A patent/IL148180A/en not_active IP Right Cessation
- 2002-02-19 NO NO20020809A patent/NO323375B1/no not_active IP Right Cessation
- 2002-02-21 BG BG106423A patent/BG65545B1/bg unknown
- 2002-11-20 HK HK02108409.6A patent/HK1046904B/zh not_active IP Right Cessation
-
2003
- 2003-04-24 US US10/422,164 patent/US6872746B2/en not_active Expired - Fee Related
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2005
- 2005-01-05 US US11/029,330 patent/US7291732B2/en not_active Expired - Fee Related
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