PL2398468T3 - Kompozycje farmaceutyczne zawierające zasadę prasugrelu lub jej farmaceutycznie dopuszczalne kwasowe sole addycyjne i sposoby ich otrzymywania - Google Patents
Kompozycje farmaceutyczne zawierające zasadę prasugrelu lub jej farmaceutycznie dopuszczalne kwasowe sole addycyjne i sposoby ich otrzymywaniaInfo
- Publication number
- PL2398468T3 PL2398468T3 PL10704517T PL10704517T PL2398468T3 PL 2398468 T3 PL2398468 T3 PL 2398468T3 PL 10704517 T PL10704517 T PL 10704517T PL 10704517 T PL10704517 T PL 10704517T PL 2398468 T3 PL2398468 T3 PL 2398468T3
- Authority
- PL
- Poland
- Prior art keywords
- processes
- preparation
- pharmaceutically acceptable
- pharmaceutical compositions
- acid addition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SI200900040 | 2009-02-17 | ||
SI200900155 | 2009-06-02 | ||
SI200900186 | 2009-07-09 | ||
SI200900194 | 2009-07-15 | ||
SI200900309 | 2009-10-20 | ||
SI200900396 | 2009-12-28 | ||
SI201000006 | 2010-01-14 | ||
EP10704517.1A EP2398468B1 (en) | 2009-02-17 | 2010-02-17 | Pharmaceutical compositions comprising prasugrel base or its pharmaceutically acceptable acid addition salts and processes for their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2398468T3 true PL2398468T3 (pl) | 2017-06-30 |
Family
ID=42104454
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL10704517T PL2398468T3 (pl) | 2009-02-17 | 2010-02-17 | Kompozycje farmaceutyczne zawierające zasadę prasugrelu lub jej farmaceutycznie dopuszczalne kwasowe sole addycyjne i sposoby ich otrzymywania |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP2398468B1 (pl) |
EA (1) | EA024980B1 (pl) |
PL (1) | PL2398468T3 (pl) |
SI (1) | SI2398468T1 (pl) |
WO (1) | WO2010094471A1 (pl) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2398468B1 (en) | 2009-02-17 | 2016-11-30 | KRKA, D.D., Novo Mesto | Pharmaceutical compositions comprising prasugrel base or its pharmaceutically acceptable acid addition salts and processes for their preparation |
DE102009036646A1 (de) | 2009-08-07 | 2011-02-10 | Ratiopharm Gmbh | Prasugrel in nicht-kristalliner Form und pharmazeutische Zusammensetzung davon |
JP2013032289A (ja) * | 2009-10-28 | 2013-02-14 | Daiichi Sankyo Co Ltd | ワックス安定製剤 |
WO2011052499A1 (ja) * | 2009-10-28 | 2011-05-05 | 第一三共株式会社 | 貯蔵安定性が改善された医薬組成物 |
EP2360159A1 (de) * | 2010-02-11 | 2011-08-24 | Ratiopharm GmbH | Prasugrel in mikronisierter, kristalliner Form und pharmazeutische Zusammensetzung davon |
KR20140110096A (ko) | 2010-04-08 | 2014-09-16 | 테바 파마슈티컬 인더스트리즈 리미티드 | 프라수그렐 염의 결정형 |
CN102232949A (zh) * | 2010-04-27 | 2011-11-09 | 孙远 | 提高药物溶出度的组合物及其制备方法 |
TR201005900A1 (tr) * | 2010-07-19 | 2012-02-21 | Sanovel İlaç San. Ve Ti̇c. A.Ş. | Geliştirilmiş stabiliteye sahip prasugrel granülleri. |
EP2608773A4 (en) | 2010-08-24 | 2014-03-05 | Univ Rutgers | FORMULATION AND MANUFACTURE OF PHARMACEUTICAL PRODUCTS BY IMPREGNATING ON POROUS SUBSTRATES |
TWI557130B (zh) * | 2011-04-25 | 2016-11-11 | 孫遠 | 提高藥物溶出度的組成物及其製備方法 |
CZ2011872A3 (cs) | 2011-12-22 | 2013-07-03 | Zentiva, K.S. | Farmaceutická formulace prasugrelu hydrobromidu |
US8603537B2 (en) | 2012-04-02 | 2013-12-10 | Egis Pharmaceuticals Plc | Prasugrel containing quickly released stable oral pharmaceutical compositions |
EP2722037A1 (en) * | 2012-10-19 | 2014-04-23 | Sanovel Ilac Sanayi ve Ticaret A.S. | Prasugrel formulations |
CN103893137B (zh) * | 2012-12-27 | 2017-09-29 | 上海创诺制药有限公司 | 一种制备普拉格雷片剂的方法 |
CN104173316B (zh) * | 2013-05-22 | 2018-05-18 | 山东新时代药业有限公司 | 一种氢溴酸普拉格雷的胶囊剂 |
EP2979693A1 (en) * | 2014-08-01 | 2016-02-03 | Zaklady Farmaceutyczne Polpharma SA | Pharmaceutical composition comprising prasugrel or pharmaceutically acceptable salt thereof and process for its preparation |
WO2016122421A1 (en) * | 2015-01-29 | 2016-08-04 | Pharmactive Ilaç Sanayi Ve Ticaret A.Ş. | Stable pharmaceutical compositions containing prasugrel base |
EP3156049A1 (en) * | 2015-10-15 | 2017-04-19 | Alembic Pharmaceuticals Limited | Pharmaceutical composition of prasugrel |
GR1009230B (el) * | 2016-10-12 | 2018-02-22 | Φαρματεν Αβεε | Φαρμακευτικο σκευασμα που περιλαμβανει βεσυλικη πρασουγρελη |
EP3528790A1 (en) | 2016-10-21 | 2019-08-28 | Laboratorios Lesvi S.L. | Pharmaceutical formulations of prasugrel and processes for the preparation thereof |
EP3486233B1 (en) | 2017-03-27 | 2021-01-27 | Fruithy Holdings Limited | Poorly soluble complex or solvate thereof, pharmaceutical composition, and application thereof |
CN111714458A (zh) * | 2019-03-18 | 2020-09-29 | 上海复星星泰医药科技有限公司 | 盐酸普拉格雷的缓释颗粒、含其的制剂及其制备方法 |
WO2021188517A1 (en) * | 2020-03-17 | 2021-09-23 | Rutgers, The State University Of New Jersey | Continuous melt-coating of active pharmaceutical ingredients using surfactants for dissolution enhancement |
WO2024033460A1 (en) * | 2022-08-12 | 2024-02-15 | F. Hoffmann-La Roche Ag | Use of co-processed excipients in continuous manufacturing of solid dosage forms |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW522014B (en) | 1997-02-07 | 2003-03-01 | Sepracor Inc | Lactose-free, non-hygroscopic and anhydrous pharmaceutical unit dosage form containing descarboethoxyloratadine |
US20030013740A1 (en) | 1998-03-27 | 2003-01-16 | Martin P. Redmon | Stable dosage forms of fluoxetine and its enantiomers |
AU782092B2 (en) | 1999-04-06 | 2005-06-30 | Wyeth Llc | Derivatives of venlafaxine and methods of preparing and using the same |
US6448323B1 (en) | 1999-07-09 | 2002-09-10 | Bpsi Holdings, Inc. | Film coatings and film coating compositions based on polyvinyl alcohol |
HU227746B1 (en) | 2000-07-06 | 2012-02-28 | Ube Industries | Hydropyridine derivative acid addition salts, process for their preparation, pharmaceutical compositions containing them and their use |
CA2379887C (en) | 2002-04-09 | 2004-01-20 | Bernard Charles Sherman | Stable tablets comprising simvastatin |
WO2004098713A2 (en) * | 2003-05-05 | 2004-11-18 | Eli Lilly And Company | Treating cardiovascular diseases with a compound of formula (i) (cs 747 - prasugrel; rn 150322-43-4) |
GB0325603D0 (en) | 2003-11-03 | 2003-12-10 | Sandoz Ag | Organic compounds |
CA2607494A1 (en) | 2005-05-10 | 2007-08-02 | Elan Pharma International Limited | Nanoparticulate clopidogrel formulations |
TWI318571B (en) | 2005-06-10 | 2009-12-21 | Lilly Co Eli | Formulation of a thienopyridine platelet aggregation inhibitor |
JP2009504737A (ja) | 2005-08-19 | 2009-02-05 | イーライ リリー アンド カンパニー | 脈管疾患の治療又は予防のためのpar−1/par−4阻害剤の使用 |
JP5535616B2 (ja) | 2006-03-31 | 2014-07-02 | ルビコン リサーチ プライベート リミテッド | 口腔内崩壊錠剤のための直接圧縮性複合材 |
WO2008060934A2 (en) * | 2006-11-14 | 2008-05-22 | Acusphere, Inc. | Formulations of tetrahydropyridine antiplatelet agents for parenteral or oral administration |
TWI428151B (zh) * | 2006-12-07 | 2014-03-01 | Daiichi Sankyo Co Ltd | 含有甘露醇或乳糖之固形製劑 |
KR20090087041A (ko) | 2006-12-07 | 2009-08-14 | 일라이 릴리 앤드 캄파니 | 프라수그렐을 포함하는 물품 |
BRPI0719395C1 (pt) * | 2006-12-07 | 2021-05-25 | Daiichi Sankyo Co Ltd | tablete revestido de filme |
WO2009062044A2 (en) | 2007-11-09 | 2009-05-14 | Dr. Reddy's Laboratories Ltd. | Processes for the preparation of prasugrel, and its salts and polymorphs |
KR20100134557A (ko) | 2008-01-11 | 2010-12-23 | 씨아이피엘에이 엘티디. | 고체 약제학적 투여 제형 |
DE602008002820D1 (de) | 2008-04-25 | 2010-11-11 | Sandoz Ag | Hydrogensulfat von 2-Acetoxy-5-(a-cyclopropylcarbonyl-2-fluorbenzyl)-4,5,6,7-tetrahydrothienoÄ3,2-cÜpyridin und dessen Zubereitung |
US20090281136A1 (en) | 2008-05-08 | 2009-11-12 | Sandeep Mhetre | Prasugrel pharmaceutical formulations |
EP2398468B1 (en) | 2009-02-17 | 2016-11-30 | KRKA, D.D., Novo Mesto | Pharmaceutical compositions comprising prasugrel base or its pharmaceutically acceptable acid addition salts and processes for their preparation |
WO2011004392A1 (en) | 2009-07-06 | 2011-01-13 | Glenmark Generics Limited | Crystalline form of prasugrel hydrobromide, preparation and application thereof |
-
2010
- 2010-02-17 EP EP10704517.1A patent/EP2398468B1/en not_active Revoked
- 2010-02-17 WO PCT/EP2010/000997 patent/WO2010094471A1/en active Application Filing
- 2010-02-17 EA EA201190145A patent/EA024980B1/ru not_active IP Right Cessation
- 2010-02-17 SI SI201031389A patent/SI2398468T1/sl unknown
- 2010-02-17 PL PL10704517T patent/PL2398468T3/pl unknown
Also Published As
Publication number | Publication date |
---|---|
SI2398468T1 (sl) | 2017-03-31 |
WO2010094471A1 (en) | 2010-08-26 |
EP2398468A1 (en) | 2011-12-28 |
EA024980B1 (ru) | 2016-11-30 |
EA201190145A1 (ru) | 2012-02-28 |
EP2398468B1 (en) | 2016-11-30 |
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