PH25941A - Yeast production of hepatitis B surface antigen - Google Patents

Yeast production of hepatitis B surface antigen

Info

Publication number
PH25941A
PH25941A PH34520A PH34520A PH25941A PH 25941 A PH25941 A PH 25941A PH 34520 A PH34520 A PH 34520A PH 34520 A PH34520 A PH 34520A PH 25941 A PH25941 A PH 25941A
Authority
PH
Philippines
Prior art keywords
hepatitis
surface antigen
regulatory regions
yeast production
carbon sources
Prior art date
Application number
PH34520A
Other languages
English (en)
Inventor
Juerg Friedrich Tschopp
Michael Miller Harpold
James Michael Cregg
Richard Gordon Buckholz
Original Assignee
Phillips Petroleum Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phillips Petroleum Co filed Critical Phillips Petroleum Co
Publication of PH25941A publication Critical patent/PH25941A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
PH34520A 1985-11-26 1986-11-24 Yeast production of hepatitis B surface antigen PH25941A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/801,713 US4895800A (en) 1985-11-26 1985-11-26 Yeast production of hepatitis B surface antigen

Publications (1)

Publication Number Publication Date
PH25941A true PH25941A (en) 1991-12-19

Family

ID=25181867

Family Applications (2)

Application Number Title Priority Date Filing Date
PH34520A PH25941A (en) 1985-11-26 1986-11-24 Yeast production of hepatitis B surface antigen
PH36040A PH25539A (en) 1985-11-26 1987-11-06 Process for preparing hepatitis b-surface antigen

Family Applications After (1)

Application Number Title Priority Date Filing Date
PH36040A PH25539A (en) 1985-11-26 1987-11-06 Process for preparing hepatitis b-surface antigen

Country Status (28)

Country Link
US (1) US4895800A (ko)
EP (1) EP0226846B1 (ko)
JP (1) JPH0763372B2 (ko)
KR (1) KR920004050B1 (ko)
CN (1) CN86107885A (ko)
AT (1) ATE92527T1 (ko)
AU (1) AU583683B2 (ko)
CA (1) CA1285895C (ko)
CS (1) CS276453B6 (ko)
DD (1) DD252614A5 (ko)
DE (1) DE3688831T2 (ko)
DK (1) DK565186A (ko)
EG (1) EG17949A (ko)
ES (1) ES2058055T3 (ko)
FI (1) FI95929C (ko)
HU (1) HUT43112A (ko)
IE (1) IE64519B1 (ko)
IL (1) IL80754A (ko)
IN (1) IN166428B (ko)
MX (1) MX4334A (ko)
NO (1) NO176025C (ko)
NZ (1) NZ218286A (ko)
PH (2) PH25941A (ko)
PL (1) PL152882B1 (ko)
PT (1) PT83819B (ko)
TW (1) TW215457B (ko)
YU (1) YU46031B (ko)
ZA (1) ZA868601B (ko)

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US5026828A (en) * 1987-02-27 1991-06-25 Merck & Co., Inc. Method of purifying recombinant pres-1/S-2/S/S hepatitis B antigen from yeast
EP0280470B1 (en) * 1987-02-27 1993-07-07 Merck & Co. Inc. Method of purifying recombinant pres-1/s-2/s hepatitis b antigen from yeast
ATE93891T1 (de) * 1987-03-09 1993-09-15 Merck & Co Inc Reinigung von rekombiniertem hepatitis-boberfl|chen-antigen.
WO1988010300A1 (en) * 1987-06-22 1988-12-29 Medico Labs Ag Heterologous viral peptide particle immunogens
EP0314240A3 (en) * 1987-10-26 1990-03-28 Merck & Co. Inc. Process for purifying recombinant hepatitis antigens
US5011915A (en) * 1987-10-26 1991-04-30 Merck & Co., Inc. Process for purifying recombinant hepatitis antigens
US5004688A (en) * 1988-04-15 1991-04-02 Phillips Petroleum Company Purification of hepatitis proteins
IL89991A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of hepatitis b pres2 protein in methylotrophic yeasts
IL89993A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of the hiv 24kda gag protein in methylotrophic yeasts
IL89989A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of human interleukin-2 in methylotrophic yeasts
IL89992A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of human serum albumin in methylotrophic yeasts
IL90021A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Process for the production of interferon
IL90161A0 (en) * 1988-05-13 1989-12-15 Phillips Petroleum Co Expression of hepatitis b s and pres2 proteins in methylotrophic yeasts
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US6197548B1 (en) 1990-04-02 2001-03-06 Medeva Pharma Limited Transformed Pichia expressing the pertactin antigen
WO1992004363A1 (en) * 1990-09-04 1992-03-19 The Salk Institute Biotechnology/Industrial Associates, Inc. Production of insulin-like growth factor-1 in methylotrophic yeast cells
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
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EP0491077A1 (en) * 1990-12-19 1992-06-24 Medeva Holdings B.V. A composition used as a therapeutic agent against chronic viral hepatic diseases
WO1992013951A1 (en) * 1991-02-04 1992-08-20 The Salk Institute Biotechnology/Industrial Associates, Inc. Production of human serum albumin in methylotrophic yeast cells
CA2063890C (en) * 1991-03-27 2007-03-13 Masami Miura Mutant aox2 promoter, microorganism carrying same, method of preparation thereof and production of heterologous protein using such microorganism
JPH06506117A (ja) * 1991-04-01 1994-07-14 メルク　エンド　カンパニー　インコーポレーテッド ピキア（Ｐｉｃｈｉａ）蛋白質分解活性に影響する遺伝子およびその使用
CA2058820C (en) * 1991-04-25 2003-07-15 Kotikanyad Sreekrishna Expression cassettes and vectors for the secretion of human serum albumin in pichia pastoris cells
US5330901A (en) * 1991-04-26 1994-07-19 Research Corporation Technologies, Inc. Expression of human serum albumin in Pichia pastoris
US5850025A (en) * 1991-09-19 1998-12-15 Sibia Neurosciences, Inc. Protection of plants against plant pathogens
EP0642355B1 (en) 1992-05-23 1998-07-15 SMITHKLINE BEECHAM BIOLOGICALS s.a. Combined vaccines comprising hepatitis b surface antigen and other antigens
ES2108278T3 (es) 1992-06-25 1997-12-16 Smithkline Beecham Biolog Composicion de vacuna con coadyuvantes.
JPH06209763A (ja) * 1993-01-13 1994-08-02 Green Cross Corp:The 変異株
CA2202351A1 (en) * 1994-10-18 1996-04-25 George Phillip Vlasuk Nematode-extracted serine protease inhibitors and anticoagulant proteins
US5945275A (en) * 1994-10-18 1999-08-31 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5872098A (en) * 1995-06-05 1999-02-16 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5866543A (en) * 1995-06-05 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5866542A (en) * 1994-10-18 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
DE69535317T2 (de) * 1994-10-18 2007-06-21 Dendreon Corp., Seattle Aus nematoden extrahierte serinprotease-inhibitoren und die koagulation hemmende proteine
US5863894A (en) * 1995-06-05 1999-01-26 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5955349A (en) * 1996-08-26 1999-09-21 Zymogenetics, Inc. Compositions and methods for producing heterologous polypeptides in Pichia methanolica
US5716808A (en) * 1995-11-09 1998-02-10 Zymogenetics, Inc. Genetic engineering of pichia methanolica
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UA79735C2 (uk) 2000-08-10 2007-07-25 Глаксосмітклайн Байолоджікалз С.А. Очищення антигенів вірусу гепатиту b (hbv) для використання у вакцинах
ATE494367T1 (de) * 2002-12-18 2011-01-15 Hoffmann La Roche Rekombinante desoxyribonuclease i aus rinder- pankreas mit hoher spezifischer aktivität
DE60319333D1 (de) * 2002-12-20 2008-04-10 Roche Diagnostics Gmbh Hitzelabile Desoxyribonuklease I-Varianten
EP1460425A1 (en) * 2003-03-17 2004-09-22 Boehringer Mannheim Gmbh Deglycosylated enzymes for conjugates
JP4411192B2 (ja) * 2003-12-05 2010-02-10 エフ．ホフマン−ラ ロシュ アーゲー 組換えで発現されるカルボキシペプチダーゼｂおよびその精製
PL1926749T3 (pl) * 2005-09-14 2011-12-30 Sanofi Aventis Deutschland Cięcie prekursorów insuliny przez wariant trypsyny
BRPI0708865A8 (pt) 2006-03-14 2019-01-22 Univ Oregon Health & Science métodos para produzir uma resposta imune à tuberculose
EP2066344B2 (en) 2006-09-07 2016-06-29 GlaxoSmithKline Biologicals S.A. Inactivated Poliovirus combination vaccine
JP4216875B2 (ja) * 2006-09-29 2009-01-28 株式会社東芝 メタノール応答性プロモーター、プロモーターと外来遺伝子を発現可能な様式で連結した融合遺伝子、ベクター、形質転換体、およびタンパク質の生産方法
AU2008221383B2 (en) 2007-02-28 2012-09-13 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Brachyury polypeptides and methods for use
UY31064A1 (es) 2007-05-02 2009-01-05 Glaxosmithkline Biolog Sa Vacuna
US9415006B2 (en) 2008-05-23 2016-08-16 The Regents Of The University Of Michigan Immunogenic compositions comprising nanoemulsion and hepatitis B virus immunogen and methods of using the same
US9005631B2 (en) 2008-08-04 2015-04-14 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Membrane proximal region of HIV gp41 anchored to the lipid layer of a virus-like particle vaccine
WO2010099472A2 (en) 2009-02-27 2010-09-02 The U.S.A. Of America, As Represented By The Secretary, Department Of Health And Human Services Spanx-b polypeptides and their use
WO2011047340A1 (en) 2009-10-16 2011-04-21 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Insertion of foreign genes in rubella virus and their stable expression in a live, attenuated viral vaccine
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WO2013152352A1 (en) 2012-04-06 2013-10-10 The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic Live, attenuated rubella vector to express vaccine antigens
ES2752190T3 (es) 2012-09-14 2020-04-03 Us Health Proteína Brachyury, vectores adenovirales que codifican proteína Brachyury y su uso
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CA2994694A1 (en) 2015-08-03 2017-02-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Brachyury deletion mutants, non-yeast vectors encoding brachyury deletion mutants, and their use

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KR850001534A (ko) * 1983-08-22 1985-03-30 제임스 에프. 나우톤 형질전환된 효모로 부터 유도된 면역원성 HBsAg
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Also Published As

Publication number Publication date
PH25539A (en) 1991-07-24
EP0226846B1 (en) 1993-08-04
ES2058055T3 (es) 1994-11-01
MX4334A (es) 1993-12-01
JPH0763372B2 (ja) 1995-07-12
AU6538486A (en) 1987-05-28
PT83819A (en) 1986-12-01
DE3688831D1 (de) 1993-09-09
EG17949A (en) 1991-03-30
NO864704D0 (no) 1986-11-25
FI864791A (fi) 1987-05-27
ZA868601B (en) 1987-06-24
CN86107885A (zh) 1987-09-23
IN166428B (ko) 1990-05-05
DK565186A (da) 1987-05-27
DK565186D0 (da) 1986-11-25
DE3688831T2 (de) 1993-11-25
JPS62190085A (ja) 1987-08-20
FI95929C (fi) 1996-04-10
KR920004050B1 (ko) 1992-05-23
YU46031B (sh) 1992-12-21
NZ218286A (en) 1991-07-26
TW215457B (ko) 1993-11-01
AU583683B2 (en) 1989-05-04
IE863021L (en) 1987-05-26
CS276453B6 (en) 1992-06-17
DD252614A5 (de) 1987-12-23
IL80754A (en) 1993-03-15
US4895800A (en) 1990-01-23
IE64519B1 (en) 1995-08-09
CA1285895C (en) 1991-07-09
NO176025C (no) 1995-01-18
NO176025B (no) 1994-10-10
EP0226846A1 (en) 1987-07-01
FI864791A0 (fi) 1986-11-25
PT83819B (pt) 1988-10-14
IL80754A0 (en) 1987-02-27
ATE92527T1 (de) 1993-08-15
CS864186A3 (en) 1992-01-15
HUT43112A (en) 1987-09-28
YU201386A (en) 1988-10-31
KR870005099A (ko) 1987-06-04
PL262598A1 (en) 1987-09-21
PL152882B1 (en) 1991-02-28
FI95929B (fi) 1995-12-29

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