PH18828A - 3a-(substituted-phenyl)-3a,4,7,7a-tetrahydro-4, 7-methano isoindolines - Google Patents

3a-(substituted-phenyl)-3a,4,7,7a-tetrahydro-4, 7-methano isoindolines

Info

Publication number
PH18828A
PH18828A PH29309A PH29309A PH18828A PH 18828 A PH18828 A PH 18828A PH 29309 A PH29309 A PH 29309A PH 29309 A PH29309 A PH 29309A PH 18828 A PH18828 A PH 18828A
Authority
PH
Philippines
Prior art keywords
isoindolines
methano
tetrahydro
phenyl
substituted
Prior art date
Application number
PH29309A
Other languages
English (en)
Inventor
Thomas Charles Mckenzie
William Joseph Fanshawe
Joseph William Epstein
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of PH18828A publication Critical patent/PH18828A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • C07D207/444Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/724,7-Endo-alkylene-iso-indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/724,7-Endo-alkylene-iso-indoles
    • C07D209/764,7-Endo-alkylene-iso-indoles with oxygen atoms in positions 1 and 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PH29309A 1982-07-28 1983-07-27 3a-(substituted-phenyl)-3a,4,7,7a-tetrahydro-4, 7-methano isoindolines PH18828A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40249482A 1982-07-28 1982-07-28

Publications (1)

Publication Number Publication Date
PH18828A true PH18828A (en) 1985-10-07

Family

ID=23592140

Family Applications (1)

Application Number Title Priority Date Filing Date
PH29309A PH18828A (en) 1982-07-28 1983-07-27 3a-(substituted-phenyl)-3a,4,7,7a-tetrahydro-4, 7-methano isoindolines

Country Status (14)

Country Link
EP (1) EP0100426A1 (cs)
JP (1) JPS5933261A (cs)
KR (1) KR840005424A (cs)
AU (1) AU1734183A (cs)
DK (1) DK344083A (cs)
ES (1) ES8504125A1 (cs)
FI (1) FI832716L (cs)
GR (1) GR77560B (cs)
IL (1) IL69150A0 (cs)
NO (1) NO832734L (cs)
PH (1) PH18828A (cs)
PL (1) PL243202A1 (cs)
PT (1) PT77114B (cs)
ZA (1) ZA835505B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007016155A2 (en) 2005-07-27 2007-02-08 Dov Pharmaceutical, Inc. Novel 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders
KR101294014B1 (ko) * 2006-01-06 2013-08-09 선오비온 파마슈티컬스 인코포레이티드 모노아민 재흡수 저해제로서의 시클로알킬아민
JP5749176B2 (ja) * 2008-12-16 2015-07-15 スノビオン プハルマセウトイカルス インコーポレイテッド トリプル再取込み阻害剤及びそれらの使用方法
US20140206740A1 (en) 2011-07-30 2014-07-24 Neurovance, Inc. Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters
CN112673010B (zh) * 2018-10-17 2023-10-27 国立大学法人大阪大学 化合物及其制造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2112548B1 (cs) * 1970-11-09 1976-07-02 Eisai Co Ltd
US3917642A (en) * 1971-11-19 1975-11-04 Cities Service Co Brominated tricyclic imide flame retardants

Also Published As

Publication number Publication date
ES524479A0 (es) 1985-04-01
PT77114B (en) 1986-01-27
FI832716A7 (fi) 1984-01-29
IL69150A0 (en) 1983-11-30
EP0100426A1 (en) 1984-02-15
DK344083A (da) 1984-01-29
PL243202A1 (en) 1985-07-02
KR840005424A (ko) 1984-11-12
GR77560B (cs) 1984-09-24
DK344083D0 (da) 1983-07-27
AU1734183A (en) 1984-02-02
FI832716L (fi) 1984-01-29
FI832716A0 (fi) 1983-07-27
ZA835505B (en) 1984-04-25
PT77114A (en) 1983-08-01
JPS5933261A (ja) 1984-02-23
ES8504125A1 (es) 1985-04-01
NO832734L (no) 1984-01-30

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