PE20051162A1 - Metodo de reduccion de impurezas en el escitalopram - Google Patents
Metodo de reduccion de impurezas en el escitalopramInfo
- Publication number
- PE20051162A1 PE20051162A1 PE2005000241A PE2005000241A PE20051162A1 PE 20051162 A1 PE20051162 A1 PE 20051162A1 PE 2005000241 A PE2005000241 A PE 2005000241A PE 2005000241 A PE2005000241 A PE 2005000241A PE 20051162 A1 PE20051162 A1 PE 20051162A1
- Authority
- PE
- Peru
- Prior art keywords
- particle size
- escitalopram
- mean
- refers
- sccitalopram
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
SE REFIERE A PARTICULAS CRISTALINAS DE OXALATO DE ESCITALOPRAM, EL CUAL LA RELACION ENTRE LA MEDIA DEL TAMANO DE PARTICULA Y EL TAMANO DE LA PARTICULA EN EL 95% DEL QUINTILO ES INFERIOR A 0.42 Y LA MEDIA ES DE POR LO MENOS 20um. LA DISTRIBUCION DEL TAMANO DE PARTICULA ES BIMODAL O POLIMODAL. DICHA PARTICULA SE OBTIENE DE: A) TRATAR UNA SOLUCION DE ESCITALOPRAM CON UNO O MAS HIDROXILOS QUE CONTIENEN IMPUREZAS CON UN DEPURADOR DE HIDROXILO; B) SEPARAR EL ESCITALOPRAM DE LOS PRODUCTOS RESULTANTES; C) TRANFERIR EN SU SAL DE OXALATO Y LLEVAR A UN SISTEMA DE SOLVENTES APROPIADOS PARA LA CRISTALIZACION; D) ENFRIAR GRADUALMENTE EN UN PERFIL DE ENFRIAMIENTO CONTROLADO. SE REFIERE TAMBIEN A UNA COMPOSICION FARMACEUTICA, SIENDO UTILES EN LA MANUFACTURA DE TABLETAS DIRECTAMENTE COMPRIMIDAS
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200400382 | 2004-03-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20051162A1 true PE20051162A1 (es) | 2006-01-16 |
Family
ID=36607154
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2005000241A PE20051162A1 (es) | 2004-03-05 | 2005-03-02 | Metodo de reduccion de impurezas en el escitalopram |
Country Status (9)
Country | Link |
---|---|
KR (1) | KR20060126587A (es) |
CN (3) | CN1925844A (es) |
AR (1) | AR047749A1 (es) |
IL (1) | IL177504A0 (es) |
MY (1) | MY142756A (es) |
PE (1) | PE20051162A1 (es) |
SG (1) | SG159504A1 (es) |
TW (1) | TW200605916A (es) |
ZA (1) | ZA200607382B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114763343A (zh) * | 2021-01-14 | 2022-07-19 | 浙江华海药业股份有限公司 | 一种西酞普兰或s-西酞普兰的纯化方法 |
CN113663356B (zh) * | 2021-08-23 | 2022-09-23 | 广西埃索凯新材料科技有限公司 | 一种应用于硫酸锰生产的结晶除杂监控系统 |
-
2005
- 2005-02-17 TW TW094104639A patent/TW200605916A/zh unknown
- 2005-02-21 SG SG201000567-6A patent/SG159504A1/en unknown
- 2005-02-21 ZA ZA200607382A patent/ZA200607382B/en unknown
- 2005-02-21 CN CNA2005800069400A patent/CN1925844A/zh active Pending
- 2005-02-21 KR KR1020067017907A patent/KR20060126587A/ko not_active Application Discontinuation
- 2005-02-21 CN CNA2009100028561A patent/CN101492436A/zh active Pending
- 2005-02-21 CN CNA2009100028557A patent/CN101492435A/zh active Pending
- 2005-02-24 AR ARP050100683A patent/AR047749A1/es not_active Application Discontinuation
- 2005-03-02 PE PE2005000241A patent/PE20051162A1/es not_active Application Discontinuation
- 2005-03-03 MY MYPI20050870A patent/MY142756A/en unknown
-
2006
- 2006-08-15 IL IL177504A patent/IL177504A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20060126587A (ko) | 2006-12-07 |
ZA200607382B (en) | 2008-05-28 |
SG159504A1 (en) | 2010-03-30 |
IL177504A0 (en) | 2006-12-10 |
TW200605916A (en) | 2006-02-16 |
CN101492435A (zh) | 2009-07-29 |
CN1925844A (zh) | 2007-03-07 |
CN101492436A (zh) | 2009-07-29 |
AR047749A1 (es) | 2006-02-15 |
MY142756A (en) | 2010-12-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant, registration | ||
FD | Application declared void or lapsed |