PE20050146A1 - Forma de dosificacion transdermica resistente a la manipulacion - Google Patents

Forma de dosificacion transdermica resistente a la manipulacion

Info

Publication number
PE20050146A1
PE20050146A1 PE2004000434A PE2004000434A PE20050146A1 PE 20050146 A1 PE20050146 A1 PE 20050146A1 PE 2004000434 A PE2004000434 A PE 2004000434A PE 2004000434 A PE2004000434 A PE 2004000434A PE 20050146 A1 PE20050146 A1 PE 20050146A1
Authority
PE
Peru
Prior art keywords
dosage form
active
agent
adverse
component
Prior art date
Application number
PE2004000434A
Other languages
English (en)
Inventor
Stephen A Howard
Bruce Reidenberg
Original Assignee
Purdue Pharma Lp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33436723&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20050146(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Purdue Pharma Lp filed Critical Purdue Pharma Lp
Publication of PE20050146A1 publication Critical patent/PE20050146A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE REFIERE A UNA FORMA DE DOSIFICACION TRANSDERMICA QUE COMPRENDE: a) UN COMPONENTE ACTIVO CON UN MATERIAL POLIMERICO DONDE EL AGENTE ACTIVO SE DISPERSA EN FORMA HOMOGENEA EN DICHO MATERIAL, ADEMAS POSEE UNA SUPERFICIE PROXIMA Y UNA DISTAL; b) UN AGENTE ADVERSO QUE SE ENCUENTRA UBICADO DISTALMENTE DEL COMPONENTE ACTIVO. LA FORMA DE DOSIFICACION COMPRENDE UNA BARRERA INTERPUESTA ENTRE LA SUPERFICIE DISTAL DEL COMPONENTE ACTIVO Y EL COMPONENTE ADVERSO DONDE LA BARRERA ES IMPERMEABLE AL ESPARCIMIENTO DEL AGENTE ACTIVO Y ADVERSO. TAMBIEN SE REFIERE A UN COMPONENTE ADHESIVO QUE CONECTA AMBOS COMPONENTES; UNA CAPA PROTECTORA SELECCIONADA DE UNA PELICULA POLIMERICA CONTINUA O SUPERPUESTA DONDE EL AGENTE ADVERSO SE INTERPONE ENTRE LA BARRERA Y LA CAPA PROTECTORA. LA FORMA DE DOSIFICACION COMPRENDE UNA PLURALIDAD DE CANALES QUE PASAN ENTRE LAS SUPERFICIES PROXIMAL Y DISTAL DEL COMPONENTE ACTIVO. EL AGENTE ACTIVO SE SELECCIONA DE UN AGONISTA OPIOIDE TAL COMO ALFENTANIL, ALILPRODINA, CODEINA, METADONA, MORFINA, ENTRE OTROS Y EL AGENTE ADVERSO ES UN ANTAGONISTA OPIOIDE SELECCIONADO DE NALOXONA, NALORFINA, CICLAZACINA, ENTRE OTROS
PE2004000434A 2003-04-30 2004-04-30 Forma de dosificacion transdermica resistente a la manipulacion PE20050146A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46724303P 2003-04-30 2003-04-30
US46723503P 2003-04-30 2003-04-30

Publications (1)

Publication Number Publication Date
PE20050146A1 true PE20050146A1 (es) 2005-03-26

Family

ID=33436723

Family Applications (2)

Application Number Title Priority Date Filing Date
PE2004000434A PE20050146A1 (es) 2003-04-30 2004-04-30 Forma de dosificacion transdermica resistente a la manipulacion
PE2008000867A PE20081297A1 (es) 2003-04-30 2004-04-30 Forma de dosificacion transdermica resistente a la manipulacion

Family Applications After (1)

Application Number Title Priority Date Filing Date
PE2008000867A PE20081297A1 (es) 2003-04-30 2004-04-30 Forma de dosificacion transdermica resistente a la manipulacion

Country Status (22)

Country Link
US (1) US8778382B2 (es)
EP (3) EP1641441B1 (es)
JP (1) JP5048324B2 (es)
KR (1) KR101159828B1 (es)
AR (1) AR047936A1 (es)
AU (1) AU2004235794B8 (es)
BR (1) BRPI0409945A (es)
CA (1) CA2522529C (es)
CL (1) CL2004000927A1 (es)
EA (1) EA009623B1 (es)
EC (1) ECSP056191A (es)
IS (1) IS2935B (es)
ME (1) ME00276B (es)
MX (1) MXPA05011703A (es)
MY (1) MY141815A (es)
NO (1) NO332157B1 (es)
NZ (1) NZ542969A (es)
PE (2) PE20050146A1 (es)
RS (1) RS20050812A (es)
TW (1) TWI350186B (es)
UA (1) UA82880C2 (es)
WO (1) WO2004098567A2 (es)

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