PE128899A1 - Ureas n,n'-sustituidas y el empleo de las mismas como medicamento - Google Patents

Ureas n,n'-sustituidas y el empleo de las mismas como medicamento

Info

Publication number
PE128899A1
PE128899A1 PE00104498A PE00104498A PE128899A1 PE 128899 A1 PE128899 A1 PE 128899A1 PE 00104498 A PE00104498 A PE 00104498A PE 00104498 A PE00104498 A PE 00104498A PE 128899 A1 PE128899 A1 PE 128899A1
Authority
PE
Peru
Prior art keywords
substituted
ureas
same
medicinal product
piridyl
Prior art date
Application number
PE00104498A
Other languages
English (en)
Inventor
Bernd Buchmann
Hartwig Hennekes
Claudia Giesen
Luisella Toschi
Werner Skuballa
Iris Pribilla
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of PE128899A1 publication Critical patent/PE128899A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE REFIERE A UREA N,N`-SUSTITUIDA DE FORMULA I, DONDE A ES ALCANODIILO C1-C10, DE PREFERENCIA METILENO, O, CO, S, SO, SO2, NH; X ES ALQUILO C1-C18, CICLOALQUILO C3-C10, ARALQUILO C4-C14; Y ES ALQUILO C1-C12, HALOGENO, H; A ESTA EN POSICION ORTO RESPECTO DE Y. SON COMPUESTOS PREFERIDOS 4,4'-METILENBIS[1-FENIL-3-(3-PIRIDILMETIL)-URETANO], 4,4-OXIBIS-[1-FENIL-3-(3-PIRIDILMETIL)-URETANO], ENTRE OTROS. LA UREA N,N'-SUSTITUIDA DE FORMULA I INHIBE LA ACCION DE LA INTERLEUCINA 4 Y PUEDE SER UTIL PARA EL TRATAMIENTO DE ALERGIAS, TRASPLANTES, LEUCEMIA Y TUMORES SOLIDOS Y EXPRESIVOS DEL RECEPTOR DE IL-4, ENFERMEDADES PARASITARIAS, LEPRA, INFECCIONES POR HONGOS, INFLAMACIONES Y ESCLERODERMIA
PE00104498A 1997-11-05 1998-11-04 Ureas n,n'-sustituidas y el empleo de las mismas como medicamento PE128899A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1997149979 DE19749979C2 (de) 1997-11-05 1997-11-05 Arzneimittel, enthaltend N,N'-substituierte Harnstoffe und deren Derivate

Publications (1)

Publication Number Publication Date
PE128899A1 true PE128899A1 (es) 2000-01-22

Family

ID=7848395

Family Applications (1)

Application Number Title Priority Date Filing Date
PE00104498A PE128899A1 (es) 1997-11-05 1998-11-04 Ureas n,n'-sustituidas y el empleo de las mismas como medicamento

Country Status (4)

Country Link
AR (1) AR010955A1 (es)
DE (1) DE19749979C2 (es)
PE (1) PE128899A1 (es)
ZA (1) ZA9810080B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6469753B1 (en) 1996-05-03 2002-10-22 Starsight Telecast, Inc. Information system
US6376524B1 (en) * 2000-06-21 2002-04-23 Sunesis Pharmaceuticals, Inc. Triphenyl compounds as interleukin-4 antagonists
EP3109233A1 (en) * 2015-06-22 2016-12-28 The Procter and Gamble Company Urea gellants

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2155856A1 (en) * 1971-10-11 1973-05-25 Leurquin Lab N-2 pyridylureas - with antiinflammatory and analgesic activity
BE792312A (fr) * 1971-12-06 1973-03-30 Quimco Gmbh Procede de preparation et de purification de thiocarbamates d'ammonium secondaire, disubstitues sur l'atome carbamique d'azote
GB1378481A (en) * 1971-12-06 1974-12-27 Quimco Gmbh Preparation of substituted ureas
US4940811A (en) * 1986-12-09 1990-07-10 Ciba-Geigy Corporation N,N-disubstituted ureas and processes for their manufacture
JP2764724B2 (ja) * 1988-04-08 1998-06-11 協同油脂 株式会社 高温で長寿命を有するグリース組成物
AT396363B (de) * 1991-01-18 1993-08-25 Chemie Linz Gmbh Verfahren zur herstellung n-mono- oder n,n-disubstituierter harnstoffe
JP2912713B2 (ja) * 1991-01-30 1999-06-28 エヌティエヌ株式会社 高温耐久性グリース組成物
DE4127562A1 (de) * 1991-08-21 1993-02-25 Chemie Linz Deutschland Verfahren zur herstellung n-mono- oder n,n-disubstituierter harnstoffe
JP3519417B2 (ja) * 1991-10-04 2004-04-12 協同油脂株式会社 高温・高速・高荷重印加用の低起動トルク性に優れる軸受用グリース組成物
JP3150787B2 (ja) * 1992-09-07 2001-03-26 株式会社日本礦油 回転機軸受用グリース組成物
JPH06240058A (ja) * 1993-02-17 1994-08-30 New Japan Chem Co Ltd ポリオレフィン用結晶核剤及びポリオレフィン系樹脂組成物
JPH07164756A (ja) * 1993-12-15 1995-06-27 Nippon Paper Ind Co Ltd 感熱記録体
WO1995033458A1 (en) * 1994-06-02 1995-12-14 Smithkline Beecham Corporation Anti-inflammatory compounds

Also Published As

Publication number Publication date
DE19749979A1 (de) 1999-05-06
ZA9810080B (en) 1999-04-05
DE19749979C2 (de) 2000-01-13
AR010955A1 (es) 2000-07-12

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal