PE12812000A1 - Aerosolized active agent delivery modulated flow resistance - Google Patents

Aerosolized active agent delivery modulated flow resistance

Info

Publication number
PE12812000A1
PE12812000A1 PE00099299A PE00099299A PE12812000A1 PE 12812000 A1 PE12812000 A1 PE 12812000A1 PE 00099299 A PE00099299 A PE 00099299A PE 00099299 A PE00099299 A PE 00099299A PE 12812000 A1 PE12812000 A1 PE 12812000A1
Authority
PE
Peru
Prior art keywords
active agent
hormone
flow
aerosolized
resistance
Prior art date
Application number
PE00099299A
Other languages
Spanish (es)
Inventor
Andrew Clark
Carlos Schuler
Steve Paboojian
Original Assignee
Inhale Therapeutic Syst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US10370298P priority Critical
Application filed by Inhale Therapeutic Syst filed Critical Inhale Therapeutic Syst
Publication of PE12812000A1 publication Critical patent/PE12812000A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder

Abstract

SE REFIERE A UNA DISPOSITIVO PARA EL SUMINISTRO DE UNA AGENTE ACTIVO AEROLIZADO A LOS PULMONES QUE COMPRENDE: UN MODULADOR DE RESISTENCIA DE FLUJO DEL AGENTE ACTIVO AEROLIZADO CON EL TIEMPO PARA PRODUCIR UN INDICE DE FLUJO INICIAL INFERIOR A 15 LITROS POR MINUTO Y SE MANTIENE DURANTE MENOS DE 10 SEGUNDOS; Refers to a device for supplying an active agent aerosolized LUNG comprising: a modulating flow resistance of the active agent aerosolized WITH TIME TO PRODUCE A FLOW RATE INITIAL less than 15 liters per minute and is held for less 10 SECONDS; DE MANERA QUE ES INDEPENDIENTE DEL MONITOREO DEL INDICE DE FLUJO Y DE LA INSTRUCCION DEL PACIENTE. SO THAT IS INDEPENDENT OF MONITORING INDEX flow and patient education. SE REFIERE TAMBIEN A UN AGENTE ACTIVO AEROLIZADO SUMINISTRADO EN FORMA NEBULIZADA QUE COMPRENDE: a)UNA SOLUCION, UNA SUSPENSION, UNA PASTA ACUOSA O POLVO SECO DEL AGENTE ACTIVO EN UNA CANTIDAD TERAPEUTICAMENTE ACTIVA; ALSO REFERS TO AN ACTIVE aerosolized agent supplied as NEBULIZED comprising: a) a solution, suspension, PASTA DRY POWDER aqueous solution or active agent a therapeutically effective amount; b)UN PROPULSOR ALTAMENTE VOLATIL DE BAJO PUNTO DE EBULLICION. b) HIGHLY VOLATILE propellant LOW BOILING POINT. EL AGENTE ACTIVO SE SELECCIONA ENTRE INSULINA, CICLOSPORINA, HORMONA PARATIROIDEA, HORMONA FOLICULO ESTIMULANTE, O-1-ANTITRIPSINA, BUDESONIDA, HORMONA DEL CRECIMIENTO, HORMONA LIBERADORA DE LA HORMONA DE CRECIMIENTO, INTERFERON ALFA, INTERFERON BETA, HORMONA LIBERADORA DE LA HORMONA LUTEINIZANTE, CALCITONINA, HEPARINA DE BAJO PESO MOLECULAR, SOMATOSTATINA, ERITROPOYETINA, FACTOR VIII, FACTOR IX, CEREDASA, CEREZINA, ANTICUERPO DE VIRUS SINCITIAL RESPIRATORIO. The active agent is selected from INSULIN, cyclosporine, Parathyroid hormone Follicle Stimulating Hormone, O-1-antitrypsin, budesonide, growth hormone releasing hormone growth hormone, interferon-alpha, interferon beta, releasing hormone luteinizing hormone, calcitonin, low molecular weight heparin, somatostatin, erythropoietin, Factor VIII, Factor IX, ceredase, CEREZINA, aNTIBODY respiratory syncytial virus. SIENDO EL FLUJO DE RESISTENCIA ENTRE 0,4 Y 2 (cm H2O)1/2 /SLM Y EL FLUJO DE RESISTENCIA BAJA ENTRE 0 Y 0,3 (cm H2O)1/2 /SLM RESISTANCE flow being between 0.4 and 2 (cm H2O) 1/2 / SLM and flow LOW RESISTANCE 0 to 0.3 (cm H2O) 1/2 / SLM
PE00099299A 1998-10-09 1999-09-30 Aerosolized active agent delivery modulated flow resistance PE12812000A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US10370298P true 1998-10-09 1998-10-09

Publications (1)

Publication Number Publication Date
PE12812000A1 true PE12812000A1 (en) 2000-11-08

Family

ID=22296604

Family Applications (1)

Application Number Title Priority Date Filing Date
PE00099299A PE12812000A1 (en) 1998-10-09 1999-09-30 Aerosolized active agent delivery modulated flow resistance

Country Status (48)

Country Link
US (1) US8408200B2 (en)
EP (1) EP1119384B1 (en)
JP (2) JP4378057B2 (en)
CN (2) CN101804230B (en)
AP (1) AP1646A (en)
AR (1) AR020760A1 (en)
AT (1) AT297771T (en)
AU (1) AU754724B2 (en)
BG (1) BG105377A (en)
BR (1) BR9914384A (en)
CA (1) CA2346791C (en)
CO (1) CO5060481A1 (en)
CZ (1) CZ20011181A3 (en)
DE (1) DE69925849T2 (en)
DK (1) DK1119384T3 (en)
DZ (1) DZ2906A1 (en)
EA (1) EA003405B1 (en)
EE (1) EE04608B1 (en)
EG (1) EG22111A (en)
ES (1) ES2243094T3 (en)
GE (1) GEP20043259B (en)
GT (1) GT199900174A (en)
HK (1) HK1040645A1 (en)
HR (1) HRP20010253B1 (en)
HU (1) HU225057B1 (en)
ID (1) ID28354A (en)
IL (1) IL142215A (en)
IS (1) IS2289B (en)
LT (2) LT4902B (en)
LV (1) LV12685B (en)
MA (1) MA25865A1 (en)
MY (1) MY129112A (en)
NO (1) NO20011742L (en)
NZ (1) NZ510853A (en)
OA (1) OA11791A (en)
PA (1) PA8484001A1 (en)
PE (1) PE12812000A1 (en)
PL (1) PL193881B1 (en)
PT (1) PT1119384E (en)
RO (1) RO120532B1 (en)
RS (1) RS49848B (en)
SA (1) SA1642B1 (en)
SK (1) SK287044B6 (en)
TN (1) TNSN99188A1 (en)
TR (1) TR200101033T2 (en)
UA (1) UA73924C2 (en)
WO (1) WO2000021594A2 (en)
ZA (1) ZA200102766B (en)

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