PE10982007A1 - inmugenica composition containing as adjuvants one saponin and polysaccharide - Google Patents

inmugenica composition containing as adjuvants one saponin and polysaccharide

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Publication number
PE10982007A1
PE10982007A1 PE2006001600A PE0016002006A PE10982007A1 PE 10982007 A1 PE10982007 A1 PE 10982007A1 PE 2006001600 A PE2006001600 A PE 2006001600A PE 0016002006 A PE0016002006 A PE 0016002006A PE 10982007 A1 PE10982007 A1 PE 10982007A1
Authority
PE
Peru
Prior art keywords
saponin
inmugenica
polysaccharide
adjuvants
composition containing
Prior art date
Application number
PE2006001600A
Other languages
Spanish (es)
Inventor
Pierre Vandepapeliere
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Priority to GBGB0525321.6A priority Critical patent/GB0525321D0/en
Priority to GB0609902A priority patent/GB0609902D0/en
Priority to GBGB0620336.8A priority patent/GB0620336D0/en
Priority to GB0620337A priority patent/GB0620337D0/en
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Priority claimed from PE0016712006A external-priority patent/PE10582007A1/en
Priority claimed from PE2006001670A external-priority patent/PE00602008A1/en
Publication of PE10982007A1 publication Critical patent/PE10982007A1/en
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37876836&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE10982007(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/002Protozoa antigens
    • A61K39/015Hemosporidia antigens, e.g. Plasmodium antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/104Pseudomonadales, e.g. Pseudomonas
    • A61K39/1045Moraxella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
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    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
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    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
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    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
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    • A61K2039/6068Other bacterial proteins, e.g. OMP
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    • A61K2039/70Multivalent vaccine
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Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: A) UN ANTIGENO O PREPARACION ANTIGENICA SELECCIONADO DE PREFERENCIA VIRUS DE LA GRIPE Y HPV QUE CONTIENE ENTRE 2,5 Y 7,5ug POR CEPA; Refers to a pharmaceutical composition comprising: a) an antigen or preparation ANTIGENIC preferably selected FLU VIRUS AND HPV containing between 2.5 and 7,5ug CEPA; B) UNA SAPONINA INMUNOLOGICAMENTE ACTIVA DERIVADA DE LA CORTEZA DE QUILLLAJA SAPONARIA MOLINA PRESENTADA EN FORMA DE LIPOSOMA EN UNA CANTIDAD DE 10ug; B) a saponin immunologically DERIVED FROM ACTIVE QUILLLAJA SAPONARIA MOLINA BARK in the form of liposome in an amount of 10ug; C) UN LIPOPOLISACARIDO TAL COMO LIPIDO A EN UNA CANTIDAD DE 1-30 ug. C) a lipopolysaccharide such as lipid A in an amount of 1-30 ug. ADICIONALMENTE PUEDE CONTENER UN ESTEROL TAL COMO COLESTEROL. IN ADDITION MAY CONTAIN a sterol such as cholesterol. DICHA COMPOSICION PROPORCIONA BUENAS PROPIEDADES ADYUVANTES CON COMBINACIONES DE LIPOPOLISACARIDO Y SAPONINA COMO INMUNOESTIMULANTES EN UNA COMPOSICION ADYUVANTE Said composition provides good adjuvant properties with combinations of lipopolysaccharide and saponin as immunostimulants in an adjuvant composition
PE2006001600A 2005-12-13 2006-12-13 inmugenica composition containing as adjuvants one saponin and polysaccharide PE10982007A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
GBGB0525321.6A GB0525321D0 (en) 2005-12-13 2005-12-13 Novel compositions
GB0609902A GB0609902D0 (en) 2006-05-18 2006-05-18 Novel composition
GBGB0620336.8A GB0620336D0 (en) 2006-10-12 2006-10-12 Vaccine
GB0620337A GB0620337D0 (en) 2006-10-12 2006-10-12 Vaccine

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PE0016712006A PE10582007A1 (en) 2005-12-22 2006-12-20 Streptococcus pneumoniae vaccine
PE0016692006A PE13052007A1 (en) 2005-12-22 2006-12-20 Immunological composition saccharide conjugated s. pneumoniae
PE2006001670A PE00602008A1 (en) 2005-12-22 2006-12-20 multivalent immunogenic composition containing a capsular saccharide conjugated to a carrier protein

Publications (1)

Publication Number Publication Date
PE10982007A1 true PE10982007A1 (en) 2007-11-07

Family

ID=37876836

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2006001600A PE10982007A1 (en) 2005-12-13 2006-12-13 inmugenica composition containing as adjuvants one saponin and polysaccharide

Country Status (28)

Country Link
US (3) US20080279926A1 (en)
EP (6) EP2364721B1 (en)
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