PE03782014A1 - Compuestos y composiciones como inhibidores de la trk - Google Patents

Compuestos y composiciones como inhibidores de la trk

Info

Publication number
PE03782014A1
PE03782014A1 PE2013001975A PE0019752013A PE03782014A1 PE 03782014 A1 PE03782014 A1 PE 03782014A1 PE 2013001975 A PE2013001975 A PE 2013001975A PE 0019752013 A PE0019752013 A PE 0019752013A PE 03782014 A1 PE03782014 A1 PE 03782014A1
Authority
PE
Peru
Prior art keywords
pyrazolo
c6
c1
pyridine
compounds
Prior art date
Application number
PE2013001975A
Other languages
English (en)
Spanish (es)
Inventor
Valentina Molteni
Yi Fan
Jon Loren
Jeffrey M Smith
Brenton T Flatt
Original Assignee
Irm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Priority to US201161446572P priority Critical
Application filed by Irm Llc filed Critical Irm Llc
Publication of PE03782014A1 publication Critical patent/PE03782014A1/es
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45815979&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE03782014(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09Radicals substituted by nitrogen atoms, not forming part of a nitro radical
PE2013001975A 2011-02-25 2012-02-23 Compuestos y composiciones como inhibidores de la trk PE03782014A1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US201161446572P true 2011-02-25 2011-02-25

Publications (1)

Publication Number Publication Date
PE03782014A1 true PE03782014A1 (es) 2014-03-28

Family

ID=45815979

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2013001975A PE03782014A1 (es) 2011-02-25 2012-02-23 Compuestos y composiciones como inhibidores de la trk

Country Status (26)

Country Link
US (1) US9102671B2 (pt)
EP (1) EP2678338B1 (pt)
JP (1) JP5959541B2 (pt)
KR (1) KR20140014184A (pt)
CN (1) CN103492384B (pt)
AP (1) AP201307103A0 (pt)
AU (1) AU2012220572A1 (pt)
BR (1) BR112013021638A2 (pt)
CA (1) CA2828219A1 (pt)
CL (1) CL2013002430A1 (pt)
CO (1) CO6751270A2 (pt)
CR (1) CR20130410A (pt)
CU (1) CU20130115A7 (pt)
DO (1) DOP2013000192A (pt)
EA (1) EA201391230A1 (pt)
ES (1) ES2551592T3 (pt)
GE (1) GEP20156285B (pt)
GT (1) GT201300209A (pt)
IL (1) IL227987D0 (pt)
MA (1) MA34969B1 (pt)
MX (1) MX2013009767A (pt)
PE (1) PE03782014A1 (pt)
SG (1) SG192795A1 (pt)
TN (1) TN2013000348A1 (pt)
WO (1) WO2012116217A1 (pt)
ZA (1) ZA201306221B (pt)

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TWI639605B (zh) 2008-10-22 2018-11-01 亞雷生物製藥股份有限公司 作為TRK激酶抑制劑之經取代吡唑并〔1,5-a〕嘧啶化合物
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CN105524058B (zh) 2014-10-21 2018-03-27 广州艾格生物科技有限公司 吡唑并[1,5‑a]吡啶类化合物及其应用
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CA3049136A1 (en) 2017-01-18 2018-07-26 Array Biopharma Inc. Substituted pyrazolo[1,5-a]pyrazine compounds as ret kinase inhibitors
WO2018136663A1 (en) 2017-01-18 2018-07-26 Array Biopharma, Inc. Ret inhibitors
CA3056754A1 (en) 2017-03-16 2018-09-20 Array Biopharma Inc. Macrocyclic compounds as ros1 kinase inhibitors
TW201922741A (zh) 2017-10-10 2019-06-16 美商亞雷生物製藥股份有限公司 結晶形式
TW201922252A (zh) 2017-10-10 2019-06-16 美商絡速藥業公司 6-(2-羥基-2-甲基丙氧基)-4-(6-(6-((6-甲氧基吡啶-3-基)甲基)-3,6-二氮雜雙環[3.1.1]庚-3-基)吡啶-3-基)吡唑并[1,5-a]吡啶-3-甲腈之調配物
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