PE00832007A1 - (5Z) -5- (6-quinoxalinilmetilideno) -2 - [(2,6-dichlorophenyl) amino] -1,3-thiazol-4 (5H) -one - Google Patents

(5Z) -5- (6-quinoxalinilmetilideno) -2 - [(2,6-dichlorophenyl) amino] -1,3-thiazol-4 (5H) -one

Info

Publication number
PE00832007A1
PE00832007A1 PE0006172006A PE0006172006A PE00832007A1 PE 00832007 A1 PE00832007 A1 PE 00832007A1 PE 0006172006 A PE0006172006 A PE 0006172006A PE 0006172006 A PE0006172006 A PE 0006172006A PE 00832007 A1 PE00832007 A1 PE 00832007A1
Authority
PE
Peru
Prior art keywords
quinoxalinilmetilideno
5z
thiazol
dichlorophenyl
5h
Prior art date
Application number
PE0006172006A
Other languages
Spanish (es)
Inventor
Kevin J Duffy
Duke M Fitch
Beth A Norton
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US68867105P priority Critical
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of PE00832007A1 publication Critical patent/PE00832007A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Abstract

REFERIDA A UN COMPUESTO (5Z)-5-(6-QUINOXALINILMETILIDENO)-2- (2,6-DICLOROFENIL)AMINO -1,3-TIAZOL-4(5H)-ONA, Y/O SUS SALES, HIDRATOS, SOLVATOS. REFERRED TO COMPOUND (5Z) -5- (6-QUINOXALINILMETILIDENO) -2- (2,6-dichlorophenyl) amino -1,3-thiazol-4 (5H) -one, and / or their salts, hydrates, solvates. TAMBIEN ESTA REFERIDA A UNA COMPOSICION FARMACEUTICA YA UN PROCEDIMIENTO DE PREPARACION. ALSO REFERRED TO A pharmaceutical composition and method of preparation. DICHO COMPUESTO ES INHIBIDOR DE LA PROTEINA hYAK3 Y ES UTIL PARA TRATAR O PREVENIR DEFICIENCIAS EN CELULAS ERITROIDES Y HEMATOPOYETICAS TALES COMO ANEMIA, ANEMIA APLASICA, MIELOSUPRESION, CITOPENIA, ENTRE OTRAS Said compound is hYAK3 protein inhibitor and is useful for treating or preventing DEFICIENCIES AND HEMATOPOIETIC erythroid cells such as anemia, aplastic anemia, myelosuppression, cytopenia, AMONG OTHERS
PE0006172006A 2005-06-08 2006-06-06 (5Z) -5- (6-quinoxalinilmetilideno) -2 - [(2,6-dichlorophenyl) amino] -1,3-thiazol-4 (5H) -one PE00832007A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US68867105P true 2005-06-08 2005-06-08

Publications (1)

Publication Number Publication Date
PE00832007A1 true PE00832007A1 (en) 2007-01-27

Family

ID=37532819

Family Applications (1)

Application Number Title Priority Date Filing Date
PE0006172006A PE00832007A1 (en) 2005-06-08 2006-06-06 (5Z) -5- (6-quinoxalinilmetilideno) -2 - [(2,6-dichlorophenyl) amino] -1,3-thiazol-4 (5H) -one

Country Status (21)

Country Link
US (1) US7674792B2 (en)
EP (1) EP1888531A4 (en)
JP (1) JP2008543770A (en)
KR (1) KR20080014017A (en)
CN (1) CN101193863A (en)
AP (1) AP200704241A0 (en)
AR (1) AR054059A1 (en)
AU (1) AU2006258032A1 (en)
BR (1) BRPI0611096A2 (en)
CA (1) CA2611480A1 (en)
EA (1) EA200702457A1 (en)
IL (1) IL187423D0 (en)
MA (1) MA29567B1 (en)
MX (1) MX2007015572A (en)
NO (1) NO20080130L (en)
NZ (1) NZ563421A (en)
PE (1) PE00832007A1 (en)
TW (1) TW200716580A (en)
UY (1) UY29581A1 (en)
WO (1) WO2006135712A2 (en)
ZA (1) ZA200709813B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008543769A (en) * 2005-06-08 2008-12-04 スミスクライン・ビーチャム・コーポレイションSmithkline Beecham Corporation (5z)-5-(6- quinoxalinium Li sulfonyl methylidene) -2 - [(2,4,6-trichlorophenyl) amino] -1,3-thiazol -4 (5h) - On
US20100286041A1 (en) * 2007-03-22 2010-11-11 Smithkline Beecham Corporation (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)amino]-1,3-thiazol-4(5h)-one
EP2164494A4 (en) * 2007-06-01 2010-06-02 Glaxosmithkline Llc Methods of treatment

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Also Published As

Publication number Publication date
EP1888531A4 (en) 2009-06-17
AP200704241A0 (en) 2007-12-31
NZ563421A (en) 2010-07-30
AU2006258032A1 (en) 2006-12-21
JP2008543770A (en) 2008-12-04
EA200702457A1 (en) 2008-04-28
CA2611480A1 (en) 2006-12-21
UY29581A1 (en) 2006-11-30
AR054059A1 (en) 2007-05-30
MX2007015572A (en) 2008-02-25
CN101193863A (en) 2008-06-04
US7674792B2 (en) 2010-03-09
KR20080014017A (en) 2008-02-13
MA29567B1 (en) 2008-06-02
EP1888531A2 (en) 2008-02-20
NO20080130L (en) 2008-01-08
BRPI0611096A2 (en) 2010-12-21
ZA200709813B (en) 2008-09-25
TW200716580A (en) 2007-05-01
US20070179144A1 (en) 2007-08-02
WO2006135712A2 (en) 2006-12-21
WO2006135712A3 (en) 2007-06-28
IL187423D0 (en) 2008-02-09

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