NZ314517A - 1-substituted phenyl-4,5-dihydro-3H-2,3-benzodiazepine derivatives and pharmaceutical compositions thereof - Google Patents
1-substituted phenyl-4,5-dihydro-3H-2,3-benzodiazepine derivatives and pharmaceutical compositions thereofInfo
- Publication number
- NZ314517A NZ314517A NZ314517A NZ31451797A NZ314517A NZ 314517 A NZ314517 A NZ 314517A NZ 314517 A NZ314517 A NZ 314517A NZ 31451797 A NZ31451797 A NZ 31451797A NZ 314517 A NZ314517 A NZ 314517A
- Authority
- NZ
- New Zealand
- Prior art keywords
- dihydro
- pharmaceutical compositions
- substituted phenyl
- benzodiazepine derivatives
- alkyl
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- -1 1-substituted phenyl-4,5-dihydro-3H-2,3-benzodiazepine Chemical class 0.000 title 1
- 229940053197 benzodiazepine derivative antiepileptics Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9600871A HU9600871D0 (en) | 1996-04-04 | 1996-04-04 | New 2,3-benzodiazepine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ314517A true NZ314517A (en) | 2000-03-27 |
Family
ID=89993864
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ314517A NZ314517A (en) | 1996-04-04 | 1997-04-03 | 1-substituted phenyl-4,5-dihydro-3H-2,3-benzodiazepine derivatives and pharmaceutical compositions thereof |
Country Status (11)
| Country | Link |
|---|---|
| KR (1) | KR970069997A (sh) |
| AT (1) | ATE254608T1 (sh) |
| AU (1) | AU720745B2 (sh) |
| BE (1) | BE1010962A4 (sh) |
| DE (1) | DE59711013D1 (sh) |
| ES (1) | ES2127699B1 (sh) |
| IT (1) | IT1290453B1 (sh) |
| NZ (1) | NZ314517A (sh) |
| UA (1) | UA45358C2 (sh) |
| YU (1) | YU13197A (sh) |
| ZA (1) | ZA972746B (sh) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU179018B (en) * | 1978-10-19 | 1982-08-28 | Gyogyszerkutato Intezet | Process for producing new 5h-2,3-benzodiazepine derivatives |
| HU186760B (en) * | 1981-03-12 | 1985-09-30 | Gyogyszerkutato Intezet | Process for preparing 3,4-dihydro-5h-2,3-aenzodiazepine derivatives |
| HU219778B (hu) * | 1990-12-21 | 2001-07-30 | Gyógyszerkutató Intézet Közös Vállalat | Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények |
| HU208429B (en) * | 1991-05-03 | 1993-10-28 | Gyogyszerkutato Intezet | Process for producing 1-/3-chloro-phenyl/-4-methyl-7,8-dimethoxy-5h-2,3-benzodiazepine of high purity |
| EP0771198B1 (en) * | 1994-08-31 | 2002-02-06 | Eli Lilly And Company | Dihydro-2,3-benzodiazepine derivatives |
-
1997
- 1997-04-01 ZA ZA972746A patent/ZA972746B/xx unknown
- 1997-04-03 NZ NZ314517A patent/NZ314517A/xx unknown
- 1997-04-03 UA UA97041584A patent/UA45358C2/uk unknown
- 1997-04-03 BE BE9700308A patent/BE1010962A4/fr not_active IP Right Cessation
- 1997-04-03 KR KR1019970012301A patent/KR970069997A/ko not_active Application Discontinuation
- 1997-04-03 YU YU13197A patent/YU13197A/sh unknown
- 1997-04-04 ES ES009700703A patent/ES2127699B1/es not_active Expired - Fee Related
- 1997-04-04 DE DE59711013T patent/DE59711013D1/de not_active Expired - Fee Related
- 1997-04-04 AT AT97105591T patent/ATE254608T1/de not_active IP Right Cessation
- 1997-04-04 IT IT000776 patent/IT1290453B1/it active IP Right Grant
- 1997-04-04 AU AU17734/97A patent/AU720745B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ES2127699B1 (es) | 2000-01-16 |
| YU13197A (sh) | 1999-09-27 |
| ITMI970776A1 (it) | 1998-10-04 |
| AU1773497A (en) | 1997-10-09 |
| KR970069997A (ko) | 1997-11-07 |
| AU720745B2 (en) | 2000-06-08 |
| ZA972746B (en) | 1998-10-09 |
| UA45358C2 (uk) | 2002-04-15 |
| ATE254608T1 (de) | 2003-12-15 |
| BE1010962A4 (fr) | 1999-03-02 |
| ES2127699A1 (es) | 1999-04-16 |
| IT1290453B1 (it) | 1998-12-03 |
| DE59711013D1 (de) | 2003-12-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL312196A1 (en) | Heterocyclic phenyl compounds as inhibitors of cyclooxygenase-2 | |
| CA2238430A1 (en) | Pyrazole derivatives, method for preparing same, and pharmaceutical compositions containing said derivatives | |
| PL324890A1 (en) | Halogenbenzimidazoles and their application as microbicides | |
| WO2001009103A3 (en) | Imidazole antiproliferative agents | |
| GEP20053421B (en) | Substituted Pyrazoles As P38 Kinase Inhibitors, Method for Their Production and Pharmaceutical Compositions Containing Them | |
| IL133825A0 (en) | Substituted 6-phenylphenanthridines, medicaments containing same and use thereof | |
| IL149370A0 (en) | 5-aryl-1h-1,2,4-triazole compounds as inhibitors of cyclooxygenase-2 and pharmaceutical compositions containing them | |
| IL105909A0 (en) | Fungicidal compositions comprising indole derivatives,certain such novel compounds and their preparation | |
| IL114599A0 (en) | Substituted pyrimidine compounds their preparation and pharmaceutical compositions containing them | |
| EP0938317A4 (en) | COMPOSITIONS AND METHODS FOR REDUCING RESPIRATORY DEPRESSION | |
| ES2136037A1 (es) | Inhibidores de sulfamida-metaloproteasa | |
| NZ334954A (en) | Substituted heterocycles as anti-tumor agents | |
| ES8301967A1 (es) | Procedimiento de preparar compuestos carbostirilicos. | |
| CA2244777A1 (en) | 2,3-benzodiazepine derivatives and their use as ampa-receptor inhibitors | |
| EP1140900A4 (en) | PYRAZOLE COMPOUNDS AND USE OF SUCH COMPOUNDS | |
| MX9707472A (es) | Diaminas radiosensibilizadoras y sus preparaciones farmaceuticas. | |
| TR200003322T2 (tr) | Geniş spektrumlu mantar ilacı olarak kullanılan suda çözülebilen azoller | |
| MX9709451A (es) | Derivados de benzisoxazol e indazol como agentes antipsicoticos. | |
| MD502G2 (ro) | Derivaţi noi ai adenozinei, procedee de preparare a lor, compoziţii farmaceutice ce le conţin | |
| MX9702203A (es) | Derivados de pirazolil-pirazol substituidos, procedimientos para su preparacion y su uso como agentes con accion herbicida. | |
| AU1998995A (en) | Substituted fused and bridged bicyclic compounds as therapeutic agents | |
| DE69330601D1 (de) | Serotoninergische ergolin derivate | |
| HUT77135A (hu) | Eljárás I típusú allergiás betegségek megelőzésére és kezelésére alkalmazható gyógyszerkészítmények előállítására | |
| NZ314517A (en) | 1-substituted phenyl-4,5-dihydro-3H-2,3-benzodiazepine derivatives and pharmaceutical compositions thereof | |
| CA2276463A1 (en) | Substituted 4-benzoyl-pyrazoles |