NO996484D0 - Ny fremgangsmåte for fremstilling av paroxetin faststoffdispersjon - Google Patents

Ny fremgangsmåte for fremstilling av paroxetin faststoffdispersjon

Info

Publication number
NO996484D0
NO996484D0 NO996484A NO996484A NO996484D0 NO 996484 D0 NO996484 D0 NO 996484D0 NO 996484 A NO996484 A NO 996484A NO 996484 A NO996484 A NO 996484A NO 996484 D0 NO996484 D0 NO 996484D0
Authority
NO
Norway
Prior art keywords
preparation
solid dispersion
new process
paroxetine
paroxetine solid
Prior art date
Application number
NO996484A
Other languages
English (en)
Other versions
NO996484L (no
Inventor
Philip J Krape
Sou-Chan Chang
Ii William A Hein
Christopher A Teleha
Original Assignee
Endo Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endo Pharmaceuticals Inc filed Critical Endo Pharmaceuticals Inc
Publication of NO996484D0 publication Critical patent/NO996484D0/no
Publication of NO996484L publication Critical patent/NO996484L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
NO996484A 1997-06-30 1999-12-27 Ny fremgangsmÕte for fremstilling av faste paroksetin- dispersjoner NO996484L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/885,068 US5955475A (en) 1997-06-30 1997-06-30 Process for manufacturing paroxetine solid dispersions
PCT/US1998/013350 WO1999000131A1 (en) 1997-06-30 1998-06-26 Novel process for manufacturing paroxetine solid dispersions

Publications (2)

Publication Number Publication Date
NO996484D0 true NO996484D0 (no) 1999-12-27
NO996484L NO996484L (no) 2000-02-25

Family

ID=25386061

Family Applications (1)

Application Number Title Priority Date Filing Date
NO996484A NO996484L (no) 1997-06-30 1999-12-27 Ny fremgangsmÕte for fremstilling av faste paroksetin- dispersjoner

Country Status (23)

Country Link
US (1) US5955475A (no)
EP (1) EP0991408B1 (no)
JP (1) JP2002514227A (no)
KR (1) KR100571044B1 (no)
CN (1) CN1121219C (no)
AP (1) AP9901725A0 (no)
AR (1) AR013131A1 (no)
AT (1) ATE290381T1 (no)
AU (1) AU733194B2 (no)
BR (1) BR9810231A (no)
CA (1) CA2295752C (no)
DE (1) DE69829286T2 (no)
ES (1) ES2239395T3 (no)
HK (1) HK1029529A1 (no)
MA (1) MA24589A1 (no)
NO (1) NO996484L (no)
NZ (1) NZ502062A (no)
OA (1) OA11518A (no)
RU (1) RU2185820C2 (no)
SA (1) SA98190227A (no)
TR (1) TR199903315T2 (no)
WO (1) WO1999000131A1 (no)
ZA (1) ZA985488B (no)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6638948B1 (en) * 1996-09-09 2003-10-28 Pentech Pharmaceuticals, Inc. Amorphous paroxetine composition
TR199903025T2 (xx) * 1997-06-10 2000-07-21 Synthon B.V. 4-Fenilpiperidin bile�imleri.
US6699882B2 (en) 1998-03-24 2004-03-02 Smithkline Beecham P.L.C. Paroxetine compositions
US6168805B1 (en) * 1998-05-07 2001-01-02 Endo Pharmaceuticals, Inc. Aqueous process for manufacturing paroxetine solid dispersions
WO2000054775A1 (de) * 1999-03-12 2000-09-21 Basf Ag Stabile pharmazeutische anwendungsform für paroxetin-anhydrat
DE19930454A1 (de) * 1999-07-02 2001-01-04 Knoll Ag Feste Paroxetin enthaltende Zubereitungen
US6503927B1 (en) * 1999-10-28 2003-01-07 Pentech Pharmaceuticals, Inc. Amorphous paroxetine composition
EP1175205B1 (en) * 1999-11-12 2006-06-14 Abbott Laboratories Solid dispersion comprising ritonavir, fenofibrate or griseofulvin
DE10000792A1 (de) * 2000-01-11 2001-07-19 Bernhard C Lippold Formulierungen von Wirkstoffen in Form einer festen Dispersion
GB0003232D0 (en) * 2000-02-11 2000-04-05 Smithkline Beecham Plc Novel composition
DK1263413T3 (da) * 2000-03-09 2006-09-11 Univ Ohio State Res Found Fremgangsmåde til fremstilling af faste dispersioner
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US6660298B1 (en) * 2000-07-27 2003-12-09 Pentech Pharmaceuticals, Inc. Paroxetine tablets and capsules
US7115279B2 (en) * 2000-08-03 2006-10-03 Curatolo William J Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors
WO2002045509A1 (en) * 2000-12-07 2002-06-13 College Of Pharmacy A novel anti-fertility agent
US6720003B2 (en) * 2001-02-16 2004-04-13 Andrx Corporation Serotonin reuptake inhibitor formulations
US20030032809A1 (en) * 2001-04-25 2003-02-13 Subhash P. Upadhyaya Optimized procedures for the manufacture of paroxetine salts
IL158991A0 (en) * 2001-06-22 2004-05-12 Pfizer Prod Inc Pharmaceutical compositions comprising low-solubility and/or acid sensitive drugs and neutralized acidic polymers
MXPA03011935A (es) * 2001-06-22 2004-03-26 Pfizer Prod Inc Composiciones farmaceuticas que contienen conjuntos de polimero y farmaco.
US20040225128A1 (en) * 2001-08-02 2004-11-11 Callewaert George Leo Paroxetine isethionate salt, process of preparation and use in the treatment of depression
IL162666A0 (en) * 2001-12-28 2005-11-20 Teva Pharma A stable pharmaceutical formulation of paroxetine hydrochloride and a process for preparation thereof
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US20050266082A1 (en) * 2004-05-26 2005-12-01 Patel Satishkumar A Preparation of stable paroxetine HC1 ER tablets using a melt granulation process
WO2006023347A1 (en) * 2004-08-20 2006-03-02 Alpharma, Inc. Paroxetine formulations
KR100691608B1 (ko) * 2005-02-21 2007-03-12 (주)나노하이브리드 염기성 고분자가 첨가된 유리 염기형 약물과 층상형 규산염의 하이브리드 및 그의 제조방법
JP5153629B2 (ja) * 2005-08-02 2013-02-27 ルピン・リミテッド 選択的セロトニン再取り込み阻害剤の新規の制御放出組成物
EP1948646A2 (en) * 2005-11-14 2008-07-30 Auspex Pharmaceuticals Inc. Substituted phenylpiperidines with serotoninergic activity and enhanced therapeutic properties
US20080033050A1 (en) 2006-08-04 2008-02-07 Richards Patricia Allison Tewe Method of treating thermoregulatory disfunction with paroxetine
WO2008067164A2 (en) * 2006-11-15 2008-06-05 Abbott Laboratories Solid pharmaceutical dosage formulations
RU2461382C2 (ru) 2006-12-22 2012-09-20 Юхан Корпорейшн Содержащая ревапразан твердая дисперсия и способ ее получения
US9138430B2 (en) * 2007-12-27 2015-09-22 Mylan Specialty L.P. Formulation and method for the release of paroxetine in the large intestine
JP5700367B2 (ja) * 2010-05-06 2015-04-15 高田製薬株式会社 パロキセチン含有フイルムコ−テイング経口製剤
EP2649989B1 (en) 2012-04-13 2017-10-18 King Saud University Method for preparing a solid dispersion, solid dispersion obtained thereby and use thereof
WO2014009970A2 (en) * 2012-07-09 2014-01-16 Hetero Research Foundation Linagliptin solid dispersion
US9381199B2 (en) 2012-07-09 2016-07-05 Hetero Research Foundation Linagliptin solid dispersion
WO2014013511A2 (en) * 2012-07-20 2014-01-23 Hetero Research Foundation Rufinamide solid dispersion
US9211290B2 (en) * 2012-12-31 2015-12-15 Noven Therapeutics, Llc Solid dispersions of amorphous paroxetine mesylate
WO2018127088A1 (en) * 2017-01-06 2018-07-12 Sunshine Lake Pharma Co., Ltd. Lurasidone solid dispersion and preparation method thereof
RU2698400C1 (ru) * 2018-12-17 2019-08-26 Георгий Сергеевич Немов Способ лечения депрессии у собак и кошек

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5147733B2 (no) * 1974-02-15 1976-12-16
US4933360A (en) * 1983-03-16 1990-06-12 Boehringer Ingelheim Pharmaceuticals, Inc. Novel chlorthalidone process and product
YU43349B (en) * 1983-03-16 1989-06-30 Boehringer Ingelheim Ltd Process for making a watersoluble, pharmaceutically acceptible dispersion of chlortalidone in solid state
ES2058061T3 (es) * 1985-10-25 1994-11-01 Beecham Group Plc Derivado de piperidina, su preparacion y su uso como medicamento.
EP0580860B2 (en) * 1991-04-16 2004-12-15 Nippon Shinyaku Company, Limited Method of manufacturing solid dispersion
AU671811B2 (en) * 1991-12-18 1996-09-12 Warner-Lambert Company A process for the preparation of a solid dispersion
IT1274241B (it) * 1993-12-03 1997-07-15 Smithkline Beecham Farma Complessi agente terapeutico/matrice polimerica dotati di migliorate caratteristiche di sapore e composizioni farmaceutiche che li contengono
GB9325644D0 (en) * 1993-12-15 1994-02-16 Smithkline Beecham Plc Novel formulation
WO1996031197A1 (en) * 1995-04-03 1996-10-10 Abbott Laboratories Homogeneous mixtures of low temperature-melting drugs and additives for controlled release
GB9514842D0 (en) * 1995-07-20 1995-09-20 Smithkline Beecham Plc Novel formulation

Also Published As

Publication number Publication date
US5955475A (en) 1999-09-21
EP0991408A1 (en) 2000-04-12
HK1029529A1 (en) 2001-04-06
CA2295752C (en) 2004-10-26
AP9901725A0 (en) 1999-12-31
MA24589A1 (fr) 1998-12-31
ZA985488B (en) 1999-04-22
RU2185820C2 (ru) 2002-07-27
CN1265593A (zh) 2000-09-06
AU733194B2 (en) 2001-05-10
OA11518A (en) 2004-02-04
AR013131A1 (es) 2000-12-13
NO996484L (no) 2000-02-25
DE69829286T2 (de) 2006-01-12
DE69829286D1 (de) 2005-04-14
CN1121219C (zh) 2003-09-17
WO1999000131A1 (en) 1999-01-07
JP2002514227A (ja) 2002-05-14
ATE290381T1 (de) 2005-03-15
EP0991408B1 (en) 2005-03-09
AU8171798A (en) 1999-01-19
CA2295752A1 (en) 1999-01-07
TR199903315T2 (xx) 2000-09-21
KR100571044B1 (ko) 2006-04-13
NZ502062A (en) 2001-10-26
BR9810231A (pt) 2000-08-08
SA98190227A (ar) 2005-12-03
KR20010020592A (ko) 2001-03-15
ES2239395T3 (es) 2005-09-16
EP0991408A4 (en) 2003-07-09

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application