NO982417L - Vektorer og fremgangsmÕter for genoverf°ring til celler - Google Patents
Vektorer og fremgangsmÕter for genoverf°ring til cellerInfo
- Publication number
- NO982417L NO982417L NO982417A NO982417A NO982417L NO 982417 L NO982417 L NO 982417L NO 982417 A NO982417 A NO 982417A NO 982417 A NO982417 A NO 982417A NO 982417 L NO982417 L NO 982417L
- Authority
- NO
- Norway
- Prior art keywords
- coat protein
- cells
- vector
- methods
- chimeric
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10345—Special targeting system for viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/40—Vectors comprising a peptide as targeting moiety, e.g. a synthetic peptide, from undefined source
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/40—Vectors comprising a peptide as targeting moiety, e.g. a synthetic peptide, from undefined source
- C12N2810/405—Vectors comprising RGD peptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/563,368 US5965541A (en) | 1995-11-28 | 1995-11-28 | Vectors and methods for gene transfer to cells |
US08/701,124 US5846782A (en) | 1995-11-28 | 1996-08-21 | Targeting adenovirus with use of constrained peptide motifs |
US08/700,846 US5962311A (en) | 1994-09-08 | 1996-08-21 | Short-shafted adenoviral fiber and its use |
PCT/US1996/019150 WO1997020051A2 (fr) | 1995-11-28 | 1996-11-27 | Vecteurs et procedes permettant de transferer des genes dans des cellules |
Publications (2)
Publication Number | Publication Date |
---|---|
NO982417D0 NO982417D0 (no) | 1998-05-27 |
NO982417L true NO982417L (no) | 1998-07-06 |
Family
ID=27415918
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO982417A NO982417L (no) | 1995-11-28 | 1998-05-27 | Vektorer og fremgangsmÕter for genoverf°ring til celler |
Country Status (17)
Country | Link |
---|---|
EP (3) | EP1616961A1 (fr) |
JP (1) | JP3420586B2 (fr) |
AT (1) | ATE382694T1 (fr) |
AU (1) | AU724189B2 (fr) |
BG (1) | BG102554A (fr) |
BR (1) | BR9612685A (fr) |
CA (1) | CA2236912C (fr) |
CZ (1) | CZ162398A3 (fr) |
EA (1) | EA199800475A1 (fr) |
EE (1) | EE9800160A (fr) |
IL (1) | IL124654A0 (fr) |
IS (1) | IS4754A (fr) |
NO (1) | NO982417L (fr) |
NZ (1) | NZ323834A (fr) |
PL (1) | PL327038A1 (fr) |
SK (1) | SK72298A3 (fr) |
WO (1) | WO1997020051A2 (fr) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5846782A (en) | 1995-11-28 | 1998-12-08 | Genvec, Inc. | Targeting adenovirus with use of constrained peptide motifs |
US6465253B1 (en) | 1994-09-08 | 2002-10-15 | Genvec, Inc. | Vectors and methods for gene transfer to cells |
US5962311A (en) * | 1994-09-08 | 1999-10-05 | Genvec, Inc. | Short-shafted adenoviral fiber and its use |
US5770442A (en) * | 1995-02-21 | 1998-06-23 | Cornell Research Foundation, Inc. | Chimeric adenoviral fiber protein and methods of using same |
FR2761689B1 (fr) * | 1997-04-02 | 1999-06-25 | Transgene Sa | Fibre adenovirale modifiee et adenovirus cibles |
DE69828193T2 (de) | 1997-10-31 | 2005-12-01 | The Board Of Regents Of The University Of Oklahoma, Norman | Hyaluronan synthase gen und seine verwendung |
AU2321999A (en) * | 1998-01-16 | 1999-08-02 | Genzyme Corporation | Adenoviral vectors with modified capsid proteins |
US20030017138A1 (en) * | 1998-07-08 | 2003-01-23 | Menzo Havenga | Chimeric adenoviruses |
IL141500A0 (en) | 1998-08-27 | 2002-03-10 | Aventis Pharma Sa | Targeted adenovirus vectors for delivery of heterologous genes |
EP1020529B1 (fr) * | 1998-11-20 | 2005-06-01 | Crucell Holland B.V. | Vecteurs d'apport de gènes munis d'un tropisme pour les cellules des muscles lisses et/ou les cellules endothéliales |
IL133032A (en) * | 1998-11-20 | 2007-06-03 | Introgene Bv | Adenoviral gene delivery vectors provided with a tissue tropism for smooth muscle cells and /or endothelial cells |
CA2364499C (fr) * | 1999-03-04 | 2008-12-23 | Introgene B.V. | Transduction de cellules ressemblant a des fibroblastes ou a des macrophages et moyens a cet effet |
CA2378324A1 (fr) * | 1999-07-06 | 2001-01-11 | Leif Lindholm | Adenovirus recombinant |
US6955808B2 (en) * | 1999-09-24 | 2005-10-18 | Uab Research Foundation | Capsid-modified recombinant adenovirus and methods of use |
CA2407518A1 (fr) * | 2000-04-26 | 2001-11-01 | Crucell Holland B.V. | Vecteurs d'adenovirus a fibres sans spicule, et leurs utilisations |
EP1285079A2 (fr) * | 2000-05-31 | 2003-02-26 | University of Saskatchewan | Adenovirus bovin modifie avec modification du tropisme |
US6579522B1 (en) * | 2000-06-27 | 2003-06-17 | Genvec, Inc. | Replication deficient adenoviral TNF vector |
GB0017720D0 (en) | 2000-07-19 | 2000-09-06 | Got A Gene Ab | Modified virus |
US6573092B1 (en) | 2000-10-10 | 2003-06-03 | Genvec, Inc. | Method of preparing a eukaryotic viral vector |
US20030086903A1 (en) | 2001-11-02 | 2003-05-08 | Genvec, Inc. | Therapeutic regimen for treating cancer |
US20040166091A1 (en) | 2003-02-24 | 2004-08-26 | Genvec, Inc. | Materials and methods for treating disorders of the ear |
AU2004238979B2 (en) | 2003-05-14 | 2008-12-18 | Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa | Broadening adenovirus tropism |
EP2168603A1 (fr) | 2003-11-14 | 2010-03-31 | GenVec, Inc. | Posologie thérapeutique pour le traitement du cancer |
JP2007228802A (ja) * | 2004-03-31 | 2007-09-13 | Dnavec Research Inc | 標的細胞への遺伝子の導入方法 |
EP1737885A2 (fr) | 2004-04-12 | 2007-01-03 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Méthode pour utiliser les vecteurs adénovirals amener une réponse immunitaire |
CA2567741A1 (fr) | 2004-05-25 | 2006-03-30 | Chimeracore, Inc. | Systeme d'administration de medicaments a base de nanoparticules a autoassemblage |
CA2620495A1 (fr) | 2005-08-31 | 2007-03-08 | Genvec, Inc. | Vaccins contre la malaria a base de vecteurs adenoviraux |
CA2629163C (fr) | 2005-11-10 | 2017-03-21 | Genvec, Inc. | Vaccin contre la fievre aphteuse a base de vecteur adenoviral |
DE602007005366D1 (de) | 2006-04-07 | 2010-04-29 | Chimeros Inc | Zusammensetzungen und verfahren zur behandlung von b-zellen-malignomen |
WO2010120874A2 (fr) | 2009-04-14 | 2010-10-21 | Chimeros, Inc. | Agents thérapeutiques chimériques, compositions, et leurs procédés d'utilisation |
WO2011047316A1 (fr) | 2009-10-16 | 2011-04-21 | The United States Of America, As Represented By The Secretary Department Of Health And Human Services | Séquences d'acides nucléiques codant pour des protéines mosaïques extensibles du vih |
CA2779632C (fr) | 2009-11-09 | 2019-08-20 | Jason Gall | Adenovirus simien et procedes d'utilisation |
WO2011057254A2 (fr) | 2009-11-09 | 2011-05-12 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Vaccins à base de vecteur adénoviral simien |
WO2012021730A2 (fr) | 2010-08-11 | 2012-02-16 | Genvec, Inc. | Vaccin contre le virus syncytial respiratoire (vsr) |
WO2012083297A2 (fr) | 2010-12-17 | 2012-06-21 | Genvec, Inc. | Vecteurs adénoviraux avec régions d'hexon modifiées |
EP2654786B1 (fr) | 2010-12-20 | 2019-02-20 | GenVec, Inc. | Vaccin contre la dengue à base d'un vecteur adénoviral |
CA2847888A1 (fr) | 2011-09-09 | 2013-03-14 | Biomed Realty, L.P. | Procedes et compositions de regulation d'un assemblage de proteines virales |
WO2013154744A1 (fr) * | 2012-04-13 | 2013-10-17 | Cornell University | Mise au point d'un vaccin conjugué hautement efficace de deuxième génération à base de nicotine destiné à traiter la dépendance à la nicotine |
EP2855669B1 (fr) | 2012-05-29 | 2018-10-10 | GenVec, Inc. | Vecteurs adénoviraux de sérotype 28 modifiés |
PT2880160T (pt) * | 2012-08-03 | 2018-12-17 | Cedars Sinai Medical Center | Isolamento de mutantes que aumentam o tráfego de proteínas para administração de fármacos |
AU2014236207B2 (en) | 2013-03-14 | 2019-05-23 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions |
TWI710635B (zh) | 2014-10-09 | 2020-11-21 | 美商珍維克公司 | 編碼人類無調同源物-1(hath1)之腺病毒載體 |
ES2933174T3 (es) | 2016-02-23 | 2023-02-02 | Salk Inst For Biological Studi | Expresión génica exógena en adenovirus terapéutico para mínimo impacto sobre la cinética viral |
EP3390428B1 (fr) | 2016-02-23 | 2019-09-25 | Salk Institute for Biological Studies | Dosage à haut débit pour mesurer la cinétique de réplication d'un adénovirus |
US11155832B2 (en) | 2016-09-30 | 2021-10-26 | Genvec, Inc. | Adenovectors for delivery of therapeutic genetic material into T cells |
CN110062630A (zh) | 2016-12-12 | 2019-07-26 | 萨克生物研究学院 | 肿瘤靶向合成腺病毒及其用途 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9223084D0 (en) * | 1992-11-04 | 1992-12-16 | Imp Cancer Res Tech | Compounds to target cells |
US5543328A (en) * | 1993-08-13 | 1996-08-06 | Genetic Therapy, Inc. | Adenoviruses having modified fiber proteins |
US5559099A (en) * | 1994-09-08 | 1996-09-24 | Genvec, Inc. | Penton base protein and methods of using same |
US5770442A (en) * | 1995-02-21 | 1998-06-23 | Cornell Research Foundation, Inc. | Chimeric adenoviral fiber protein and methods of using same |
-
1996
- 1996-11-27 BR BR9612685A patent/BR9612685A/pt not_active Application Discontinuation
- 1996-11-27 EE EE9800160A patent/EE9800160A/xx unknown
- 1996-11-27 NZ NZ323834A patent/NZ323834A/xx unknown
- 1996-11-27 SK SK722-98A patent/SK72298A3/sk unknown
- 1996-11-27 EP EP05021223A patent/EP1616961A1/fr not_active Withdrawn
- 1996-11-27 PL PL96327038A patent/PL327038A1/xx unknown
- 1996-11-27 IL IL12465496A patent/IL124654A0/xx unknown
- 1996-11-27 WO PCT/US1996/019150 patent/WO1997020051A2/fr active IP Right Grant
- 1996-11-27 JP JP52072097A patent/JP3420586B2/ja not_active Expired - Fee Related
- 1996-11-27 EA EA199800475A patent/EA199800475A1/ru unknown
- 1996-11-27 CZ CZ981623A patent/CZ162398A3/cs unknown
- 1996-11-27 AU AU10868/97A patent/AU724189B2/en not_active Ceased
- 1996-11-27 AT AT96940927T patent/ATE382694T1/de not_active IP Right Cessation
- 1996-11-27 EP EP96940927A patent/EP0863987B1/fr not_active Expired - Lifetime
- 1996-11-27 EP EP04028530A patent/EP1518933A1/fr not_active Withdrawn
- 1996-11-27 CA CA002236912A patent/CA2236912C/fr not_active Expired - Fee Related
-
1998
- 1998-05-25 IS IS4754A patent/IS4754A/is unknown
- 1998-05-27 NO NO982417A patent/NO982417L/no not_active Application Discontinuation
- 1998-06-18 BG BG102554A patent/BG102554A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EA199800475A1 (ru) | 1998-12-24 |
SK72298A3 (en) | 1998-12-02 |
WO1997020051A2 (fr) | 1997-06-05 |
IL124654A0 (en) | 1998-12-06 |
BR9612685A (pt) | 1999-07-20 |
CA2236912C (fr) | 2006-04-25 |
NO982417D0 (no) | 1998-05-27 |
ATE382694T1 (de) | 2008-01-15 |
JP3420586B2 (ja) | 2003-06-23 |
JPH11501219A (ja) | 1999-02-02 |
NZ323834A (en) | 2000-01-28 |
AU724189B2 (en) | 2000-09-14 |
EP0863987A2 (fr) | 1998-09-16 |
AU1086897A (en) | 1997-06-19 |
MX9804203A (es) | 1998-10-31 |
EP0863987B1 (fr) | 2008-01-02 |
EE9800160A (et) | 1998-12-15 |
EP1616961A1 (fr) | 2006-01-18 |
IS4754A (is) | 1998-05-25 |
CZ162398A3 (cs) | 1998-10-14 |
BG102554A (en) | 1999-04-30 |
CA2236912A1 (fr) | 1997-06-05 |
EP1518933A1 (fr) | 2005-03-30 |
WO1997020051A3 (fr) | 1997-08-28 |
PL327038A1 (en) | 1998-11-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |