NO965505L - Nye salter av 2-£(2,6-diklorfenyl)aminer|fenylacetoksyeddiksyre med organiske, basiske kationer - Google Patents

Nye salter av 2-£(2,6-diklorfenyl)aminer|fenylacetoksyeddiksyre med organiske, basiske kationer

Info

Publication number
NO965505L
NO965505L NO965505A NO965505A NO965505L NO 965505 L NO965505 L NO 965505L NO 965505 A NO965505 A NO 965505A NO 965505 A NO965505 A NO 965505A NO 965505 L NO965505 L NO 965505L
Authority
NO
Norway
Prior art keywords
pct
dichlorophenyl
organic basic
amines
acetic acid
Prior art date
Application number
NO965505A
Other languages
English (en)
Other versions
NO965505D0 (no
Inventor
Alfred Sallmann
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO965505L publication Critical patent/NO965505L/no
Publication of NO965505D0 publication Critical patent/NO965505D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/03—Monoamines
    • C07C211/05—Mono-, di- or tri-ethylamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/10—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with one amino group and at least two hydroxy groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Salt av 2-[(2,6-diklorfenyl)amin]fenylacetoksyeddiksyre med en organisk basisk kation med formel I COOCH2COO e R ' d), hvor RI og R2 uavhengig er laverealkyl eller, hvis RI er hydrogen, har H-(Ri)(R2) : betydningen arginin eller lysin eller, hvis RI er metyl, har H-N(Rj)(R2) betydningen N- ,-. metylglukamin. . Forbindelsen har analgesisk aktivitet såvel som antiflammatorisk aktivitet, passenede i behandlingen av tilstander slik som rheumatoid arthritis, ankylosing spondylitis, lum- i bare smerter, vridninger og okulær inflammasjon. Forbindelsen har videre en forbedret stabilitet i vandige oppløsninger sammenlignet med alkalimetallsaltene, f.eks. natrium og kalium.
NO965505A 1994-06-29 1996-12-20 Nye salter av 2-((2,6-diklorfenyl)amin)fenylacetoksyeddiksyre med organiske, basiske kationer NO965505D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94810382 1994-06-29
PCT/IB1995/000524 WO1996000716A1 (en) 1994-06-29 1995-06-28 New salts of 2-[(2,6-dichlorophenyl)amine]phenylacetoxyacetic acid with organic basic cations

Publications (2)

Publication Number Publication Date
NO965505L true NO965505L (no) 1996-12-20
NO965505D0 NO965505D0 (no) 1996-12-20

Family

ID=8218277

Family Applications (1)

Application Number Title Priority Date Filing Date
NO965505A NO965505D0 (no) 1994-06-29 1996-12-20 Nye salter av 2-((2,6-diklorfenyl)amin)fenylacetoksyeddiksyre med organiske, basiske kationer

Country Status (17)

Country Link
US (1) US5708024A (no)
EP (1) EP0767777B1 (no)
JP (1) JPH11505503A (no)
AT (1) ATE178884T1 (no)
AU (1) AU2628895A (no)
CA (1) CA2192682A1 (no)
CZ (1) CZ380596A3 (no)
DE (1) DE69509091T2 (no)
DK (1) DK0767777T3 (no)
ES (1) ES2132672T3 (no)
FI (1) FI965157A0 (no)
GR (1) GR3030625T3 (no)
HU (1) HUT75341A (no)
MX (1) MX9700210A (no)
NO (1) NO965505D0 (no)
PL (1) PL318014A1 (no)
WO (1) WO1996000716A1 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO4960662A1 (es) 1997-08-28 2000-09-25 Novartis Ag Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados
GB0007239D0 (en) * 2000-03-24 2000-05-17 Nycomed Imaging As Use
PE20040844A1 (es) 2002-11-26 2004-12-30 Novartis Ag Acidos fenilaceticos y derivados como inhibidores de la cox-2
KR100749162B1 (ko) 2005-10-24 2007-08-14 주식회사 엔지켐 아세클로페낙 아미노산염의 제조방법
CN105213010A (zh) 2008-01-14 2016-01-06 康文图斯整形外科公司 用于骨折修补的装置和方法
RU2012122654A (ru) * 2009-11-05 2013-12-10 Алкем Лабораториз Лтд. Стабильная фармацевтическая инъекционная композиция ацеклофенака и способ ее получения

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT368129B (de) * 1980-06-03 1982-09-10 Gerot Pharmazeutika Verfahren zur herstellung neuer salze von o-(2,6- dichloranilino)-phenylessigsaeure
AT370721B (de) * 1981-02-24 1983-04-25 Ciba Geigy Ag Verfahren zur herstellung von neuen salzen der 2- (2,6-dichloranilino)-phenylessigsaeure, der
CH651821A5 (en) * 1981-02-18 1985-10-15 Ciba Geigy Ag Salts of a phenylacetic acid, and a process for their preparation
ES520813A0 (es) * 1983-03-21 1984-05-16 Prodes Sa Procedimiento para la obtencion del ester del acido 2-(2,6-diclorofenil)amino bencenoacetico con acido glicolico.
IT1228242B (it) * 1986-11-13 1991-06-05 Ricerfarma Srl Milano Sale del diclofenac con idrossietilpirrolidina e composizioni farmaceutiche che lo contengono
IT1250636B (it) * 1991-07-04 1995-04-21 Ricerche Di Schiena Del Dr Mic Sale del diclofenac, metodo di preparazione e composizioni farmaceutiche che lo contengono.

Also Published As

Publication number Publication date
ATE178884T1 (de) 1999-04-15
MX9700210A (es) 1998-01-31
FI965157A (fi) 1996-12-20
US5708024A (en) 1998-01-13
EP0767777B1 (en) 1999-04-14
EP0767777A1 (en) 1997-04-16
FI965157A0 (fi) 1996-12-20
HU9603590D0 (en) 1997-02-28
ES2132672T3 (es) 1999-08-16
CA2192682A1 (en) 1996-01-11
WO1996000716A1 (en) 1996-01-11
JPH11505503A (ja) 1999-05-21
DK0767777T3 (da) 1999-10-25
GR3030625T3 (en) 1999-10-29
HUT75341A (en) 1997-05-28
DE69509091T2 (de) 1999-09-09
AU2628895A (en) 1996-01-25
DE69509091D1 (de) 1999-05-20
PL318014A1 (en) 1997-05-12
CZ380596A3 (en) 1997-08-13
NO965505D0 (no) 1996-12-20

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