NO941905D0 - Process for Preparation of a Proline Boronate Ester - Google Patents

Process for Preparation of a Proline Boronate Ester

Info

Publication number
NO941905D0
NO941905D0 NO941905A NO941905A NO941905D0 NO 941905 D0 NO941905 D0 NO 941905D0 NO 941905 A NO941905 A NO 941905A NO 941905 A NO941905 A NO 941905A NO 941905 D0 NO941905 D0 NO 941905D0
Authority
NO
Norway
Prior art keywords
preparation
boronate ester
proline boronate
proline
ester
Prior art date
Application number
NO941905A
Other languages
Norwegian (no)
Other versions
NO941905L (en
Inventor
Roger Snow
Terence A Kelly
Julian Adams
Simon Coutts
Clark Perry
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of NO941905D0 publication Critical patent/NO941905D0/en
Publication of NO941905L publication Critical patent/NO941905L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
NO941905A 1991-11-22 1994-05-20 Process for Preparation of a Proline Boronate Ester NO941905L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79614891A 1991-11-22 1991-11-22
US93619892A 1992-08-26 1992-08-26
PCT/US1992/009845 WO1993010127A1 (en) 1991-11-22 1992-11-19 Method for making a prolineboronate ester

Publications (2)

Publication Number Publication Date
NO941905D0 true NO941905D0 (en) 1994-05-20
NO941905L NO941905L (en) 1994-07-14

Family

ID=27121696

Family Applications (1)

Application Number Title Priority Date Filing Date
NO941905A NO941905L (en) 1991-11-22 1994-05-20 Process for Preparation of a Proline Boronate Ester

Country Status (17)

Country Link
EP (1) EP0641347A1 (en)
JP (1) JPH07501078A (en)
CN (1) CN1073946A (en)
AU (1) AU661362B2 (en)
CA (1) CA2123128A1 (en)
CZ (1) CZ124494A3 (en)
FI (1) FI942345A0 (en)
HU (1) HUT67937A (en)
IL (1) IL103817A0 (en)
MX (1) MX9206628A (en)
NO (1) NO941905L (en)
NZ (1) NZ245207A (en)
PT (1) PT101079A (en)
SI (1) SI9200332A (en)
SK (1) SK59294A3 (en)
TW (1) TW232697B (en)
WO (1) WO1993010127A1 (en)

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US6825169B1 (en) 1991-10-22 2004-11-30 Trustees Of Tufts College Inhibitors of dipeptidyl-aminopeptidase type IV
US5965532A (en) 1996-06-28 1999-10-12 Trustees Of Tufts College Multivalent compounds for crosslinking receptors and uses thereof
US6100234A (en) * 1997-05-07 2000-08-08 Tufts University Treatment of HIV
US6040145A (en) 1997-05-07 2000-03-21 Tufts University Potentiation of the immune response
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BR9910251A (en) 1998-05-04 2001-01-02 Point Therapeutics Inc Hematopoietic stimulation
ATE231512T1 (en) 1998-06-05 2003-02-15 Point Therapeutics Inc CYCLIC BOROPROLINE COMPOUNDS
US6979697B1 (en) 1998-08-21 2005-12-27 Point Therapeutics, Inc. Regulation of substrate activity
US6890904B1 (en) 1999-05-25 2005-05-10 Point Therapeutics, Inc. Anti-tumor agents
JP2003523396A (en) * 2000-02-25 2003-08-05 ノボ ノルディスク アクティーゼルスカブ Inhibition of beta cell degeneration
WO2003063903A2 (en) * 2002-02-01 2003-08-07 Probiodrug Ag Modulation of t lymphocytes using dp iv inhibitors
US7767828B2 (en) 2003-11-12 2010-08-03 Phenomix Corporation Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US7576121B2 (en) 2003-11-12 2009-08-18 Phenomix Corporation Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US7317109B2 (en) 2003-11-12 2008-01-08 Phenomix Corporation Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
BRPI0416444B8 (en) 2003-11-12 2021-05-25 Chiesi Farm Spa heterocyclic boronic acid compound, pharmaceutical composition, and, pharmaceutical combination comprising the same
AU2004290897B2 (en) 2003-11-17 2009-02-26 Novartis Ag Use of dipeptidyl peptidase IV inhibitors
SI3366283T1 (en) 2004-01-20 2021-12-31 Novartis Ag Direct compression formulation and process
AR049631A1 (en) * 2004-04-27 2006-08-23 Wyeth Corp COUPLING PROCESS FOR THE GENERATION OF PIRROL REACTIVE DERIVATIVES -2- CARBONITRILE N- REPLACED WITH BORO CONTENT TO PRODUCE BIARILOS
DOP2006000008A (en) 2005-01-10 2006-08-31 Arena Pharm Inc COMBINED THERAPY FOR THE TREATMENT OF DIABETES AND RELATED AFFECTIONS AND FOR THE TREATMENT OF AFFECTIONS THAT IMPROVE THROUGH AN INCREASE IN THE BLOOD CONCENTRATION OF GLP-1
AU2006246719A1 (en) 2005-05-19 2006-11-23 Genentech, Inc. Fibroblast activation protein inhibitor compounds and methods
US7825139B2 (en) 2005-05-25 2010-11-02 Forest Laboratories Holdings Limited (BM) Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
CN1331835C (en) * 2005-10-18 2007-08-15 武汉大学 Preparation method of optically active beta-hydroxy ketone
JP5270369B2 (en) 2005-12-19 2013-08-21 タフツ ユニバーシティー/トラスティーズ オブ タフツ カレッジ Soft protease inhibitor and its pro-soft type
CL2007001011A1 (en) 2006-04-11 2008-05-16 Arena Pharm Inc METHOD FOR THE IDENTIFICATION OF GIP SECRETAGOGS, GASTRIC INHIBITOR POLYPEPTIDE; AND USE OF A PROTEIN G COUPLED RECEIVER TO CLASSIFY TEST COMPOUNDS AS GIP SECRETAGOGS.
PE20071221A1 (en) 2006-04-11 2007-12-14 Arena Pharm Inc GPR119 RECEPTOR AGONISTS IN METHODS TO INCREASE BONE MASS AND TO TREAT OSTEOPOROSIS AND OTHER CONDITIONS CHARACTERIZED BY LOW BONE MASS, AND COMBINED THERAPY RELATED TO THESE AGONISTS
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CN103467565A (en) * 2008-06-17 2013-12-25 米伦纽姆医药公司 Boronate ester compounds and pharmaceutical compositions thereof
AR077642A1 (en) 2009-07-09 2011-09-14 Arena Pharm Inc METABOLISM MODULATORS AND THE TREATMENT OF DISORDERS RELATED TO THE SAME
AU2011237775A1 (en) 2010-04-06 2012-11-22 Arena Pharmaceuticals, Inc. Modulators of the GPR119 receptor and the treatment of disorders related thereto
EP3323818A1 (en) 2010-09-22 2018-05-23 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
US20140018371A1 (en) 2011-04-01 2014-01-16 Arena Pharmaceuticals, Inc. Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
WO2012145361A1 (en) 2011-04-19 2012-10-26 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2012145604A1 (en) 2011-04-22 2012-10-26 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2012145603A1 (en) 2011-04-22 2012-10-26 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2012170702A1 (en) 2011-06-08 2012-12-13 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2013055910A1 (en) 2011-10-12 2013-04-18 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2014074668A1 (en) 2012-11-08 2014-05-15 Arena Pharmaceuticals, Inc. Modulators of gpr119 and the treatment of disorders related thereto
US9523687B2 (en) 2014-02-28 2016-12-20 Institut Pasteur Levels of CXCL 10/IP-10 forms and soluble CD26/DPPIV activity as early predictive biomarkers for HIV/SIV associated mucosal inflammation and progression towards AIDS
CR20160577A (en) 2014-05-20 2017-01-06 Millennium Pharm Inc PROTEASOME INHIBITORS CONTAINING BORO TO BE USED AFTER A PRIMARY CANCER THERAPY
EP3267994A4 (en) 2015-03-09 2018-10-31 Intekrin Therapeutics, Inc. Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy
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CN110996951A (en) 2017-04-03 2020-04-10 科赫罗斯生物科学股份有限公司 PPAR gamma agonists for the treatment of progressive supranuclear palsy
CN108047257B (en) * 2017-12-17 2020-03-13 沧州普瑞东方科技有限公司 Preparation process of chiral N-BOC-pyrrolidine-2-boric acid
CN110452258B (en) * 2019-09-03 2021-01-01 上海馨远医药科技有限公司 Preparation method of dipeptide valine boron proline salt

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US4935493A (en) * 1987-10-06 1990-06-19 E. I. Du Pont De Nemours And Company Protease inhibitors
WO1991016339A1 (en) * 1990-04-14 1991-10-31 New England Medical Center Hospitals, Inc. Inhibitors of dipeptidyl-aminopeptidase type iv
GB9017694D0 (en) * 1990-08-13 1990-09-26 Sandoz Ltd Improvements in or relating to organic chemistry

Also Published As

Publication number Publication date
TW232697B (en) 1994-10-21
NO941905L (en) 1994-07-14
SI9200332A (en) 1993-06-30
IL103817A0 (en) 1993-04-04
EP0641347A1 (en) 1995-03-08
AU3136893A (en) 1993-06-15
CZ124494A3 (en) 1995-07-12
FI942345A (en) 1994-05-20
NZ245207A (en) 1994-07-26
JPH07501078A (en) 1995-02-02
WO1993010127A1 (en) 1993-05-27
HUT67937A (en) 1995-05-29
SK59294A3 (en) 1995-02-08
PT101079A (en) 1994-02-28
FI942345A0 (en) 1994-05-20
CA2123128A1 (en) 1993-05-27
AU661362B2 (en) 1995-07-20
CN1073946A (en) 1993-07-07
MX9206628A (en) 1993-05-01
HU9401350D0 (en) 1994-08-29

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