NO941905D0 - Process for Preparation of a Proline Boronate Ester - Google Patents
Process for Preparation of a Proline Boronate EsterInfo
- Publication number
- NO941905D0 NO941905D0 NO941905A NO941905A NO941905D0 NO 941905 D0 NO941905 D0 NO 941905D0 NO 941905 A NO941905 A NO 941905A NO 941905 A NO941905 A NO 941905A NO 941905 D0 NO941905 D0 NO 941905D0
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- boronate ester
- proline boronate
- proline
- ester
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79614891A | 1991-11-22 | 1991-11-22 | |
US93619892A | 1992-08-26 | 1992-08-26 | |
PCT/US1992/009845 WO1993010127A1 (en) | 1991-11-22 | 1992-11-19 | Method for making a prolineboronate ester |
Publications (2)
Publication Number | Publication Date |
---|---|
NO941905D0 true NO941905D0 (en) | 1994-05-20 |
NO941905L NO941905L (en) | 1994-07-14 |
Family
ID=27121696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO941905A NO941905L (en) | 1991-11-22 | 1994-05-20 | Process for Preparation of a Proline Boronate Ester |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0641347A1 (en) |
JP (1) | JPH07501078A (en) |
CN (1) | CN1073946A (en) |
AU (1) | AU661362B2 (en) |
CA (1) | CA2123128A1 (en) |
CZ (1) | CZ124494A3 (en) |
FI (1) | FI942345A0 (en) |
HU (1) | HUT67937A (en) |
IL (1) | IL103817A0 (en) |
MX (1) | MX9206628A (en) |
NO (1) | NO941905L (en) |
NZ (1) | NZ245207A (en) |
PT (1) | PT101079A (en) |
SI (1) | SI9200332A (en) |
SK (1) | SK59294A3 (en) |
TW (1) | TW232697B (en) |
WO (1) | WO1993010127A1 (en) |
Families Citing this family (44)
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---|---|---|---|---|
US6825169B1 (en) | 1991-10-22 | 2004-11-30 | Trustees Of Tufts College | Inhibitors of dipeptidyl-aminopeptidase type IV |
US5965532A (en) | 1996-06-28 | 1999-10-12 | Trustees Of Tufts College | Multivalent compounds for crosslinking receptors and uses thereof |
US6100234A (en) * | 1997-05-07 | 2000-08-08 | Tufts University | Treatment of HIV |
US6040145A (en) | 1997-05-07 | 2000-03-21 | Tufts University | Potentiation of the immune response |
CA2304206A1 (en) | 1997-09-29 | 1999-04-08 | Point Therapeutics, Inc. | Stimulation of hematopoietic cells in vitro |
BR9910251A (en) | 1998-05-04 | 2001-01-02 | Point Therapeutics Inc | Hematopoietic stimulation |
ATE231512T1 (en) | 1998-06-05 | 2003-02-15 | Point Therapeutics Inc | CYCLIC BOROPROLINE COMPOUNDS |
US6979697B1 (en) | 1998-08-21 | 2005-12-27 | Point Therapeutics, Inc. | Regulation of substrate activity |
US6890904B1 (en) | 1999-05-25 | 2005-05-10 | Point Therapeutics, Inc. | Anti-tumor agents |
JP2003523396A (en) * | 2000-02-25 | 2003-08-05 | ノボ ノルディスク アクティーゼルスカブ | Inhibition of beta cell degeneration |
WO2003063903A2 (en) * | 2002-02-01 | 2003-08-07 | Probiodrug Ag | Modulation of t lymphocytes using dp iv inhibitors |
US7767828B2 (en) | 2003-11-12 | 2010-08-03 | Phenomix Corporation | Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
US7576121B2 (en) | 2003-11-12 | 2009-08-18 | Phenomix Corporation | Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
US7317109B2 (en) | 2003-11-12 | 2008-01-08 | Phenomix Corporation | Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
BRPI0416444B8 (en) | 2003-11-12 | 2021-05-25 | Chiesi Farm Spa | heterocyclic boronic acid compound, pharmaceutical composition, and, pharmaceutical combination comprising the same |
AU2004290897B2 (en) | 2003-11-17 | 2009-02-26 | Novartis Ag | Use of dipeptidyl peptidase IV inhibitors |
SI3366283T1 (en) | 2004-01-20 | 2021-12-31 | Novartis Ag | Direct compression formulation and process |
AR049631A1 (en) * | 2004-04-27 | 2006-08-23 | Wyeth Corp | COUPLING PROCESS FOR THE GENERATION OF PIRROL REACTIVE DERIVATIVES -2- CARBONITRILE N- REPLACED WITH BORO CONTENT TO PRODUCE BIARILOS |
DOP2006000008A (en) | 2005-01-10 | 2006-08-31 | Arena Pharm Inc | COMBINED THERAPY FOR THE TREATMENT OF DIABETES AND RELATED AFFECTIONS AND FOR THE TREATMENT OF AFFECTIONS THAT IMPROVE THROUGH AN INCREASE IN THE BLOOD CONCENTRATION OF GLP-1 |
AU2006246719A1 (en) | 2005-05-19 | 2006-11-23 | Genentech, Inc. | Fibroblast activation protein inhibitor compounds and methods |
US7825139B2 (en) | 2005-05-25 | 2010-11-02 | Forest Laboratories Holdings Limited (BM) | Compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
CN1331835C (en) * | 2005-10-18 | 2007-08-15 | 武汉大学 | Preparation method of optically active beta-hydroxy ketone |
JP5270369B2 (en) | 2005-12-19 | 2013-08-21 | タフツ ユニバーシティー/トラスティーズ オブ タフツ カレッジ | Soft protease inhibitor and its pro-soft type |
CL2007001011A1 (en) | 2006-04-11 | 2008-05-16 | Arena Pharm Inc | METHOD FOR THE IDENTIFICATION OF GIP SECRETAGOGS, GASTRIC INHIBITOR POLYPEPTIDE; AND USE OF A PROTEIN G COUPLED RECEIVER TO CLASSIFY TEST COMPOUNDS AS GIP SECRETAGOGS. |
PE20071221A1 (en) | 2006-04-11 | 2007-12-14 | Arena Pharm Inc | GPR119 RECEPTOR AGONISTS IN METHODS TO INCREASE BONE MASS AND TO TREAT OSTEOPOROSIS AND OTHER CONDITIONS CHARACTERIZED BY LOW BONE MASS, AND COMBINED THERAPY RELATED TO THESE AGONISTS |
EP2146210A1 (en) | 2008-04-07 | 2010-01-20 | Arena Pharmaceuticals, Inc. | Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditions modulated by PYY |
CN103467565A (en) * | 2008-06-17 | 2013-12-25 | 米伦纽姆医药公司 | Boronate ester compounds and pharmaceutical compositions thereof |
AR077642A1 (en) | 2009-07-09 | 2011-09-14 | Arena Pharm Inc | METABOLISM MODULATORS AND THE TREATMENT OF DISORDERS RELATED TO THE SAME |
AU2011237775A1 (en) | 2010-04-06 | 2012-11-22 | Arena Pharmaceuticals, Inc. | Modulators of the GPR119 receptor and the treatment of disorders related thereto |
EP3323818A1 (en) | 2010-09-22 | 2018-05-23 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
US20140018371A1 (en) | 2011-04-01 | 2014-01-16 | Arena Pharmaceuticals, Inc. | Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto |
WO2012145361A1 (en) | 2011-04-19 | 2012-10-26 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
WO2012145604A1 (en) | 2011-04-22 | 2012-10-26 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
WO2012145603A1 (en) | 2011-04-22 | 2012-10-26 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
WO2012170702A1 (en) | 2011-06-08 | 2012-12-13 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
WO2013055910A1 (en) | 2011-10-12 | 2013-04-18 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
WO2014074668A1 (en) | 2012-11-08 | 2014-05-15 | Arena Pharmaceuticals, Inc. | Modulators of gpr119 and the treatment of disorders related thereto |
US9523687B2 (en) | 2014-02-28 | 2016-12-20 | Institut Pasteur | Levels of CXCL 10/IP-10 forms and soluble CD26/DPPIV activity as early predictive biomarkers for HIV/SIV associated mucosal inflammation and progression towards AIDS |
CR20160577A (en) | 2014-05-20 | 2017-01-06 | Millennium Pharm Inc | PROTEASOME INHIBITORS CONTAINING BORO TO BE USED AFTER A PRIMARY CANCER THERAPY |
EP3267994A4 (en) | 2015-03-09 | 2018-10-31 | Intekrin Therapeutics, Inc. | Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy |
WO2018162722A1 (en) | 2017-03-09 | 2018-09-13 | Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke | Dpp-4 inhibitors for use in treating bone fractures |
CN110996951A (en) | 2017-04-03 | 2020-04-10 | 科赫罗斯生物科学股份有限公司 | PPAR gamma agonists for the treatment of progressive supranuclear palsy |
CN108047257B (en) * | 2017-12-17 | 2020-03-13 | 沧州普瑞东方科技有限公司 | Preparation process of chiral N-BOC-pyrrolidine-2-boric acid |
CN110452258B (en) * | 2019-09-03 | 2021-01-01 | 上海馨远医药科技有限公司 | Preparation method of dipeptide valine boron proline salt |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4935493A (en) * | 1987-10-06 | 1990-06-19 | E. I. Du Pont De Nemours And Company | Protease inhibitors |
WO1991016339A1 (en) * | 1990-04-14 | 1991-10-31 | New England Medical Center Hospitals, Inc. | Inhibitors of dipeptidyl-aminopeptidase type iv |
GB9017694D0 (en) * | 1990-08-13 | 1990-09-26 | Sandoz Ltd | Improvements in or relating to organic chemistry |
-
1992
- 1992-11-18 MX MX9206628A patent/MX9206628A/en unknown
- 1992-11-19 PT PT101079A patent/PT101079A/en not_active Application Discontinuation
- 1992-11-19 AU AU31368/93A patent/AU661362B2/en not_active Expired - Fee Related
- 1992-11-19 SK SK592-94A patent/SK59294A3/en unknown
- 1992-11-19 SI SI19929200332A patent/SI9200332A/en unknown
- 1992-11-19 HU HU9401350A patent/HUT67937A/en unknown
- 1992-11-19 WO PCT/US1992/009845 patent/WO1993010127A1/en not_active Application Discontinuation
- 1992-11-19 JP JP5509442A patent/JPH07501078A/en active Pending
- 1992-11-19 CA CA002123128A patent/CA2123128A1/en not_active Abandoned
- 1992-11-19 CZ CZ941244A patent/CZ124494A3/en unknown
- 1992-11-19 EP EP92925238A patent/EP0641347A1/en not_active Withdrawn
- 1992-11-20 TW TW081109304A patent/TW232697B/zh active
- 1992-11-20 IL IL103817A patent/IL103817A0/en unknown
- 1992-11-20 NZ NZ24520792A patent/NZ245207A/en unknown
- 1992-11-23 CN CN92113215A patent/CN1073946A/en active Pending
-
1994
- 1994-05-20 FI FI942345A patent/FI942345A0/en not_active Application Discontinuation
- 1994-05-20 NO NO941905A patent/NO941905L/en unknown
Also Published As
Publication number | Publication date |
---|---|
TW232697B (en) | 1994-10-21 |
NO941905L (en) | 1994-07-14 |
SI9200332A (en) | 1993-06-30 |
IL103817A0 (en) | 1993-04-04 |
EP0641347A1 (en) | 1995-03-08 |
AU3136893A (en) | 1993-06-15 |
CZ124494A3 (en) | 1995-07-12 |
FI942345A (en) | 1994-05-20 |
NZ245207A (en) | 1994-07-26 |
JPH07501078A (en) | 1995-02-02 |
WO1993010127A1 (en) | 1993-05-27 |
HUT67937A (en) | 1995-05-29 |
SK59294A3 (en) | 1995-02-08 |
PT101079A (en) | 1994-02-28 |
FI942345A0 (en) | 1994-05-20 |
CA2123128A1 (en) | 1993-05-27 |
AU661362B2 (en) | 1995-07-20 |
CN1073946A (en) | 1993-07-07 |
MX9206628A (en) | 1993-05-01 |
HU9401350D0 (en) | 1994-08-29 |
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